Cycloguanil and its parent compound proguanil demonstrate distinct activities against Plasmodium falciparum malaria parasites transformed with human dihydrofolate reductase

Molecular Pharmacology

Volumn 54, Issue 6, 1998, Pages 1140-1147

  Fidock, David A ^a,b   Nomura, Takashi ^a   Wellems, Thomas E ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4,6 DIAMINO 1,2 DIHYDRO 2,2 DIMETHYL 1 [3 (2,4,5 TRICHLOROPHENOXY)PROPOXY] 1,3,5 TRIAZINE; CHLOROQUINE; CYCLOGUANIL; DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE INHIBITOR; FANSIDAR; METHOTREXATE; N [3 (2,4,5 TRICHLOROPHENOXY)PROPOXY] N' ISOPROPYLIMIDOCARBONIMIDIC DIAMIDE; PROGUANIL; PYRIMETHAMINE;

ANTIPROTOZOAL ACTIVITY; ARTICLE; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

EID: 0032407858     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.54.6.1140     Document Type: Article

References (14)

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