Glial cells as targets of viral infection in the human central nervous system

Progress in Brain Research

Volumn 132, Issue , 2001, Pages 721-735

  Schweighardt, Becky ^a   Atwood, Walter J ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RECEPTOR;

ASTROCYTE; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; DEMENTIA; GENE EXPRESSION; GLIA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MICROGLIA; OLIGODENDROGLIA; PAPOVAVIRUS; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; REVIEW; VIROGENESIS; VIRUS INFECTION; VIRUS INFECTIVITY; VIRUS INHIBITION; VIRUS LATENCY; VIRUS PATHOGENESIS;

EID: 0035783750     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(01)32113-1     Document Type: Article

References (139)

1. Albright, A.V., Strizki, J., Harouse, J.M., Lavi, E., O'Connor, M. and Gonzalez-Scarano, F. (1996) HIV-1 infection of cultured human adult oligodendrocytes. Virology, 217(1): 211-219.
2. Alkhatib, F., Combadiere, C., Broder, C., Feng, Y., Kennedy, P.E., Murphy, P.M. and Berger, E.A. (1996) CC CKR5: A RANTES, MIP-1 alpha, MIP-1 beta receptor as a fusion cofactor for macrophage-tropic HIV-1. Science, 272: 1955-1958.
3. Amemiya, K., Traub, R., Durham, L. and Major, E.O. (1989) Interaction of a nuclear factor-1-like protein with the regulatory region of the human polyomavirus JC virus. J. Biol. Chem., 264:7025-7032.
4. Amemiya, K., Traub, R., Durham, L. and Major, E.O. (1992) Adjacent nuclear factor-1 and activator protein binding sites in the enhancer of the neurotropic JC virus. A common characteristic of many brain-specific genes. J. Biol. Chem., 267: 14204-14211.
5. Amemiya, K., Durham, L. and Major, E.O. (1994) Overexpression and reactivation of binding activity of the recombinant CTF/NF-1 transcription factor. Protein Expr. Purif., 5: 57-64.
6. An, S.F., Groves, M., Giometto, B., Beckett, A.A.J. and Scaravelli, F. (1999a) Detection and localisation of HIV-1 DNA and RNA in fixed adult AIDS brain by polymerase chain reaction/in situ hybridization technique. Acta Neuropathol., 98: 481-487.
7. An, S.F., Groves, M., Gray, F. and Scaravilli, F. (1999b) Early entry and widespread cellular involvement of HIV-1 DNA in brains of HIV-1 positive asymptomatic individuals. J. Neuropathol. Exp. Neurol., 58: 1156-1162.
8. Anderson, H.A., Chen, Y. and Norkin, L.C. (1996) Bound Simian Virus 40 translocates to caveolin enriched membrane domains, and its entry is inhibited by drugs that selectively disrupt caveolae. Mol. Biol. Cell, 7: 1825-1834.
9. Anderson, H.A., Chen, Y. and Norkin, L.C. (1998) MHC class I molecules are enriched in caveolae but do not enter with simian virus 40. J. Gen. Virol., 79: 1469-1477.
10. Atwood, W.J. and Norkin, L.C. (1989) Class I major histocompatibility proteins as cell surface receptors for simian virus 40. J. Virol., 63: 4474-4477.
11. Atwood, W.J., Amemiya, K., Traub, R., Harms, J. and Major, E.O. (1992) Interaction of the human polyomavirus. JCV, with human B-lymphocytes. Virology, 190: 716-723.
12. Atwood, W.J., Berger, J.R., Kaderman, R., Tornatore, C.S. and Major, E.O. (1993) Human immunodeficiency virus type 1 infection of the brain. Clin. Microbiol. Rev., 6: 339-366.
13. Bagasra, O., Lavi, E., Bobroski, L., Khalili, K., Pestaner, J.P. and Pomerantz, R.J. (1996) Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: Identification by the combination of in situ PCR and immunohistochemistry. AIDS, 10: 573-585.
14. Basak, S., Turner, H. and Compans, R.W. (1992) Expression of SV40 receptors on apical surfaces of polarized epithelial cells. Virology, 190: 393-402.
15. Bass, D.M. and Greenberg, H.B. (1992) Strategies for the identification of icosahedral virus receptors. J. Clin. Invest., 89: 3-9.
16. Bass, D.M., Mackow, E. and Greenberg, H.B. (1991) Identification and partial characterization of rhesus rotavirus binding glycoprotein on murine enterocytes. Virology, 183: 602-610.
17. Bauer, P.H., Bronson, R.T., Fung, S.C., Freund, R., Stehle, T., Harrison, S.C. and Benjamin, T.L. (1995) Genetic and structural analysis of a virulence determinant in polyomavirus VP1. J. Virol., 69: 7925-7931.
18. Bauer, P.H., Cui, C., Stehle, T., Harrison, S.C., DeCaprio, J.A. and Benjamin, T.L. (1999) Discrimination between sialic acid containing receptors and pseudoreceptors regulates polyomavirus spread in the mouse. J. Virol., 73: 5826-5832.
19. Bell, J.E. (1998) The neuropathology of adult HIV infection. Rev. Neurol., 154(12): 816-829.
20. Berger, J.R. and Major, E.O. (1999) Progressive multifocal leukoencephalopathy. Semin. Neurol., 19: 193-200.
21. Bolen, J.B. and Consigli, R.A. (1979) Differential adsorption of polyoma virions and capsids to mouse kidney cells and guinea pig erythrocytes. J. Virol., 32: 679-683.
22. Brack-Wemer, R. (1999) Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis. AIDS, 13: 1-22.
23. Brannagan, T.H., Nuovo, G.J., Hays, A.P. and Latov, N. (1997) Human immunodeficiency virus infection of dorsal root ganglion neurons detected by polymerase chain reaction in situ hybridization. Ann. Neurol., 42: 368-372.
24. Breau, W.C., Atwood, W.J. and Norkin, L.C. (1992) Class I major histocompatibility proteins are an essential component of the simian virus 40 receptor. J. Virol., 66: 2037-2045.
25. Brew, B.J., Dunbar, N., Pemberton, L. and Kaldor, J. (1996) Predictive markers of AIDS dementia complex: CD4 cell count and cerebrospinal fluid concentrations of beta 2-microglobulin and neopterin. J. Infect. Dis., 174: 294-298.
26. Brodt, H.R., Kamps, B.S., Gute, P., Knupp, B., Staszewski, S. and Helm, E.B. (1997) Changing incidence of AIDS-defining illnesses in the era of antiretroviral combination therapy. AIDS, 11: 1731-1738.
27. Budka, H. (1991) Neuropathology of human immunodeficiency virus infection. Brain Pathol., 1: 163-175.
28. Chan, D.C. and Kim, P.S. (1998) HIV entry and its inhibition. Cell, 93: 681-684.
29. Chen, M.H. and Benjamin, T. (1997) Roles of N-glycans with alpha 2,6 as well as alpha 2,3 linked sialic acid in infection by polyoma virus. Virology, 233: 440-442.
30. Conant, K., Garzino-Demo, A., Nath, A., McArthur, J.C., Halliday, W., Power, C., Gallo, R.C. and Major, E.O. (1998) Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia. Proc. Natl. Acad. Sci. USA, 95: 3117-3121.
31. Conant, K., Tornatore, C.S., Atwood, W.J., Meyers, K., Traub, R. and Major, E.O. (1994) In vivo and in vitro infection of the astrocyte by HIV-1. Adv. Neuroimmunol., 4: 1-3.
32. Davis, L., Hjelle, B., Miller, V., Palmer, D., Llewellyn, A., Merlin, T., Young, S., Mills, R., Wachsman, W. and Wiley, C. (1992) Early viral brain invasion in iatrogenic human immunodeficiency virus. Neurology, 42: 1736-1739.
33. Dawson, V.L., Dawson, T.M., Bartley, D.A., Uhl, G.R. and Snyder, S.H. (1993) Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J. Neurosci., 13: 2651-2661.
34. Deng, H., Liu, R., Ellmeier, W., Choe, S., Unatmaz, D., Burkhart, M., DiMarzio, P., Marmon, S., Sutton, R.E., Hill, C.M., Davis, C.B., Peiper, S.C., Schall, T.J., Littman, D.R. and Landau, N.R. (1996) Identification of a major co-receptor for primary isolates of HIV-1. Nature, 381: 661-666.
35. Doranz, B.J., Rucker, J., Yi, Y., Smith, R.J., Samson, M., Peiper, S.C., Parmentier, M., Collman, R.G. and Doms, R.W. (1996) A dual tropic primary HIV-1 isolate that used fusin and the beta-chemokine receptors CCR5, CCR3 and CKR-2b as fusion cofactors. Cell, 85: 1149-1158.
36. Dore, G.J., Correll, P.K., Li, Y., Kaldor, J.M., Cooper, D.A. and BJ, B. (1999) Changes to AIDS dementia complex in the era of highly active antiretroviral therapy. AIDS, 13: 1249-1253.
37. Dubensky, T.W., Freund, R., Dawe, C.J. and Benjamin, T.L. (1991) Polyomavirus replication in mice: Influences of VP1 type and route of innoculation. J. Virol., 65: 342-349.
38. Dubois, V., Lafon, M.E., Ragnaud, J.M., Pellegrin, J.L., Damasio, F., Baudouin, C., Michaud, V. and Fleury, H.J.A. (1996) Detection of JC virus DNA in the peripheral blood leukocytes of HIV-infected patients. AIDS, 10: 353-358.
39. Dubois, V., Dutronc, H., Lafon, M.-E., Poinsot, V., Pellegrin, J.-L., Ragnaud, J.-M., Ferrer, A.-M. and Fleury, H.J.A. (1997) Latency and reactivation of JC Virus in peripheral blood of human immunodeficiency virus type-1 infected patients. J. Clin. Microbiol., 35: 2288-2292.
40. Dubois, V., Moret, H., Lafon, M.E., Janvresse, C.B., Dussaix, E., Icart, J., Karaterki, A., Ruffault, A., Taoufik, Y., Vignoli, C. and Ingrand, D. (1998) Prevalence of JC virus viraemia in HIV-infected patients with or without neurological disorders: A prospective study. J. Neurovirol., 4: 539-544.
41. Elliot, B.C., Aromin, I., Flanigan, T.P. and Mileno, M. (1996) Prolonged remission of AIDS associated progressive multifocal leukoencephalopathy with combined antiretroviral therapy. XI International Conference on AIDS, Vancouver, Abstract Th.B. 183.
42. Elsner, C. and Dorries, K. (1992) Evidence of human polyomavirus BK and JC infection in normal brain tissue. Virology, 191: 72-80.
43. Epstein, L. and Gendelman, H. (1993) Human immunodeficiency virus type 1 infection of the nervous system: Pathogenetic mechanisms. Ann. Neurol., 33: 429-436.
44. Esiri, M., Morris, C. and Millard, P. (1991) Fate of oligodendrocytes in HIV-1 infection. AIDS, 5: 1081-1121.
45. Everall, I., Luthert, P. and Lantos, P. (1991) Neuronal loss in the frontal cortex in HIV infection. Lancet, 337: 1119-1121.
46. Feigenbaum, L., Khalili, K., Major, E. and Khoury, G. (1987) Regulation of the host range of human papovavirus JCV. Proc. Natl. Acad. Sci. USA, 84: 3695-3698.
47. Freund, R., Calderone, A., Dawe, C.J. and Benjamin, T.L. (1991a) Polyomavirus tumor induction in mice, effects of polymorphisms of VP1 and large T antigen. J. Virol., 65: 335-341.
48. Freund, R., Garcea, R.L., Sahli, R. and Benjamin, T.L. (1991b) A single amino acid substitution in polyomavirus VP1 correlates with plaque size and hemagglutination behavior. J. Virol., 65: 350-355.
49. Fried, H., Cahan, L. and Paulson, J. (1981) Polyoma virus recognizes specific sialyloligosaccharide receptors on host cells. Virology, 109: 188-192.
50. Gabuzda, D., Ho, D., de la Monte, S., Hirsch, M., Rota, T. and Sobel, R. (1986) Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS. Ann. Neurol., 20: 289-295.
51. Gelbard, H.A., James, H.J., Sharer, L.R., Perry, S.W., Kazee, A.M., Saito, Y., Blumberg, B.M. and Epstein, L.G. (1995) Apoptotic neurons in brains from paediatric patients with HIV-1 encephalitis and progressive encephalopathy. Neuropathol. Appl. Neurobiol., 21: 208-217.
52. Griffith, G.R. and Consigli, R.A. (1986) Cross-linking of a polyoma attachment protein to its mouse kidney cell receptor. J. Virol., 58: 773-781.
53. Hao, H.N. and Lyman, W.D. (1999) HIV infection of fetal human astrocytes: The potential role of a receptor-mediated endocytic pathway. Brain Res., 823: 24-32.
54. Haun, G., Keppler, O.T., Bock, C.T., Herrmann, M., Zentgraf, H. and Pawlita, M. (1993) The cell surface receptor is a major determinant restricting the host range of the B-lymphotropic papovavirus. J. Virol., 67: 7482-7492.
55. He, J., Chen, Y., Farzan, M., Choe, H., Ohagen, A., Gartner, S., Busciglio, J., Yang, X., Hofmann, W., Newman, W., Mackay, C.R., Sodroski, J. and Gabuzda, D. (1997) CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature, 385: 645-649.
56. Henson, J.W. (1994) Regulation of the glial-specific JC virus early promoter by the transcription factor Sp 1. J. Biol. Chem., 269: 1046-1050.
57. Herrmann, M., Oppenlander, M. and Pawlita, M. (1995) Fast and high affinity binding of B-lymphotropic papovavirus to human B-lymphoma cell lines. J. Virol., 69: 6797-6804.
58. Herrmann, M., Wilhelm von der Leith, C., Stehling, P., Reutter, W. and Pawlita, M. (1997) Consequences of subtle sialic acid modification on the murine polyomavirus receptor. J. Virol., 71: 5922-5931.
59. Hesselgesser, J. and Horuk, R. (1999) Chemokine and chemokine receptor expression in the central nervous system. J. Neurovirol., 5: 13-26.
60. Hofling, K., Brossmer, R., Klenk, H. and Herrler, G. (1996) Transfer of an esterase-resistant receptor analog to the surface of influenza C virions results in reduced infectivity due to aggregate formation. Virology, 218: 127-133.
61. Houff, S.A., Major, E.O., Katz, D.A., Kufta, C.V., Sever, J.L., Pittaluga, S., Roberts, J.R., Girt, J., Saini, N. and Lux, W. (1988) Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy. New Engl. J. Med., 318: 301-305.
62. Houff, S.A., Katz, D., Kufta, C.V. and Major, E.O. (1989) A rapid method for in situ hybridization for viral DNA in brain biopsies from patients with AIDS. AIDS, 3: 843-845.
63. Itoh, S. (1995) Analysis of the cellular tropism of human polyoma JC virus (JCV). Hokkaido Igaku Zasshi, 70: 765-774.
64. Ito, T., Suzuki, Y., Mitnaul, L., Vines, A., Kida, H. and Kawaoka, Y. (1997) Receptor specificity of influenza A viruses correlates with the agglutination of erythrocytes from different animal species. Virology, 227: 493-499.
65. Johnson, R.T. (1998) Viral Infections of the Nervous System, 2nd Ed. Lippincott-Raven, Philadelphia.
66. Jordan, C.A., Watkins, B.A., Kufta, C. and Dubois-Dalcq, M. (1991) Infection of brain microglial cells by human immunodeficiency virus type 1. J. Virol., 65: 736-742.
67. Keppler, O.T., Herrmann, M., Oppenlander, M., Meschede, W. and Pawlita, M. (1994) Regulation of susceptibility and cell surface receptor for the B-lymphotropic papovavirus by N glycosylation. J. Virol., 68: 6933-6939.
68. Keppler, O.T., Stehling, P., Herrmann, M., Kayser, H., Grunow, D., Reutter, W. and Pawlita, M. (1995) Biosynthetic modulation of sialic acid-dependent virus-receptor interactions of two primate polyoma viruses. J. Biol. Chem., 270: 1308-1314.
69. Kerza-Kwiatecki, A.P. and Amini, S. (1999) CNS as an HIV-1 reservoir; BBB and drug delivery. J. Neurovirol., 5: 113-114.
70. Khalili, K., Rappaport, J. and Khoury, G. (1988) Nuclear factors in human brain cells bind specifically to the JCV regulatory region. EMBO J., 7: 1205-1210.
71. Khalili, K., Krynska, B., Del Valle, L., Katsetos, C.D. and Croul, S. (1999) Medulloblastomas and the human neurotropic polyomavirus JC virus. Lancet, 3: 1152-1153.
72. Koenig, S., Gendelman, H., Orenstein, J., Dal Canto, M., Pezeshkpour, G., Yungbluth, M., Janotta, F., Aksamit, A., Martin, M. and Fauci, A. (1986) Detection of AIDS virus in macrophages in brain tissue from AIDS patients. Science, 233: 1089-1093.
73. Kolson, D.L., Lavi, E. and Gonzalez-Scarano, F. (1998) The effects of human immunodeficiency virus in the central nervous system. Adv. Virus Res., 50: 1-700.
74. Kreutzberg, G.W. (1997) Cellular pathology of the central nervous system. Greenfield's Neuropathol., 2: 85-151.
75. Krynska, B., Del Valle, L., Croul, S., Gordon, J., Katsetos, C.C., Carbone, M., Giordano, A., and Khalili, K. (1999a) Detection of human neurotropic JC virus DNA sequence and expression of the viral oncogenic protein in pediatric medulloblastomas. Proc. Natl. Acad. Sci. USA, 28: 11519-11524.
76. Krynska, B., Otte, J., Franks, R., Khalili, K. and Croul, S. (1999b) Human ubiquitous JCV (CY) T-antigen gene induces brain tumors in experimental animals. Oncogene, 7: 39-46.
77. Kwong, P.D., Wyatt, R., Robinson, J., Sweet, R.W., Sodroski, J. and Hendrickson, W.A. (1998) Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature, 393: 648-659.
78. Laghi, L., Randolf, A.E., Chauhan, D.P., Marra, G., Major, E.O., Neel, J.V. and Boland, C.R. (1999) JC virus DNA is present in the mucosa of the human colon and in colorectal cancers. Proc. Natl. Acad. Sci. USA, 96: 7484-7489.
79. Lipton, S.A. (1994) HIV-related neuronal injury. Mol. Neurobiol., 8: 181-196.
80. Lisignoli, G., Monaco, M.C.G., Facchini, A., Toneguzzi, S., Cattini, L., Hilbert, D.M., Lavaroni, S., Belvedere, O. and Degrassi, A. (1997) In vitro cultured stromal cells from human tonsils display a distinct phenotype and induce B cell adhesion and proliferation. Eur. J. Immunol., 26: 17-27.
81. Littman, D.R. (1998) Chemokine receptors: Keys to AIDS pathogenesis. Cell, 93: 677-680.
82. Liu, C.K., Hope, A.P. and Atwood, W.J. (1998a) The human polyomavirus, JCV, does not share receptor specificity with SV40 on human glial cells. J. Neurovirol., 4: 49-58.
83. Liu, C.K., Wei, G. and Atwood, W.J. (1998b) Infection of glial cells by the human polyomavirus JC is mediated by an N-linked glycoprotein containing terminal alpha 2-6 linked sialic acids. J. Virol., 72: 4643-4649.
84. Ma, M., Geiger, J.D. and Nath, A. (1994) Characterization of a novel binding site for the human immunodeficiency virus type 1 envelope protein gp120 on human fetal astrocytes. J. Virol., 68: 6824-6828.
85. Mackay, R.L. and Consigli, R.A. (1976) Early events in polyoma virus infection: Attachment, penetration, and nuclear entry. J. Virol., 19: 620-636.
86. Major, E.O., Miller, A.E., Mourrain, P., Traub, R.G., de Widt, E. and Sever, J. (1985) Establishment of a line of human fetal glial cells that supports JC virus multiplication. Proc. Natl. Acad. Sci. USA, 82: 1257-1261.
87. Major, E.O., Amemiya, K., Tornatore, C.S., Houff, S.A. and Berger, J.R. (1992) Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain. Clin. Microbiol. Rev., 5: 49-73.
88. Mantyjarvi, R., Arstila, P. and Meurman, O. (1972) Hemagglutination by BK virus, a tentative new member of the papovavirus. Infect. Immun., 6: 824-828.
89. Markowitz, R.B., Eaton, B.A., Kubik, M.F., Latorra, D., MacGregor, J.A. and Dynan, W.S. (1991) BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions. J. Virol., 65: 4515-4519.
90. Markowitz, R.B., Thompson, H.C., Mueller, J.F., Cohen, J.A. and Dynan, W.S. (1993) Incidence of BK virus and JC virus viruria in human immunodeficiency virus infected and uninfected subjects. J. Infect. Dis., 167: 13-20.
91. Marsh, M. and Helenius, A. (1989) Virus entry into animal cells. Adv. Virus Res., 36: 107-151.
92. Masliah, E., Ge, N., Morey, M., DeTeresa, R., Terry, R. and Wiley, C. (1992) Spectrum of human immunodeficiency virus associated neocortical damage. Ann. Neurol., 32: 321-329.
93. McArthur, J.C., McClernon, D.R., Cronin, M.F., Nance-Sproson, T.E., Saab, A.J., St Clair, M. and Lanier, E.R. (1997) Relationship between human immunodeficiency virus-associated dementia and viral load in cerebrospinal fluid and brain. Ann. Neurol., 42: 689-698.
94. Mei, Y.F. and Wadell, G. (1995) Molecular determinants of adenovirus tropism. Curr. Top. Microbiol. Immunol., 199: 213-228.
95. Mendelsohn, C.L., Wimmer, E. and Racaniello, V.R. (1989) Cellular receptor for poliovirus: Molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. Cell, 56: 855-865.
96. Mezes, B. and Amati, P. (1994) Mutations of polyomavirus VP1 allow in vitro growth in undifferentiated cells and modify in vivo tissue replication specificity. J. Virol., 68: 1196-1199.
97. Monaco, M.G.C., Atwood, W.J., Gravell, M., Tornatore, C.S. and Major, E.O. (1996) JCV infection of hematopoietic progenitor cells, primary B lymphocytes, and tonsillar stromal cells: Implication for viral latency. J. Virol., 70: 7004-7012.
98. Monaco, M.C., Jensen, P.N., Hou, J., Durham, L.C. and Major, E.O. (1998) Detection of JC virus DNA in human tonsil tissue: Evidence for site of initial viral infection. J. Virol., 72: 9918-9923.
99. Mori, M., Kurata, H., Tajima, M. and Shimada, H. (1991) JC virus detection by in situ hybridization in brain tissue from elderly patients. Ann. Neurol., 29: 428-432.
100. Nath, A., Hartloper, V., Furer, M. and Fowke, K.R. (1995) Infection of human fetal astrocytes with HIV-1: Viral tropism and the role of cell to cell contact in viral transmission. J. Neuropathol. Exp. Neurol., 54: 320-330.
101. Norkin, L.C. (1982) Papovaviral persistent infections. Microbiol. Rev., 46: 384-425.
102. Norkin, L.C., Steinberg, V.I. and Kosz-Vnenchak, M. (1985) Human glioblastomas persistently infected with SV40 carry non-defective viral genomes. J. Virol., 53: 658-666.
103. Nuovo, G.J. and Alfieri, M.L. (1996) AIDS dementia is associated with massive, activated HIV-1 infection and concomitant expression of several cytokines. Mol. Med., 2: 358-366.
104. Nuovo, G.J., Gallery, F., MacConnell, P. and Braun, A. (1994) In situ detection of polymerase chain reaction-amplified HIV-1 nucleic acids and tumor necrosis factor-alpha RNA in the central nervous system. Am. J. Pathol., 144: 659-666.
105. Peuchen, S., Bolanos, J.P., Heales, S.J.R., Almeida, A., Duchen, M.R. and Clark, J.B. (1997) Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system. Prog. Neurobiol., 52: 261-281.
106. Pho, M.T., Ashok, A. and Atwood, W.J. (2000) JC Virus enters human glial cells by clathrin dependent receptor mediated endocytosis. J. Virol., 74(5): 2288-2292.
107. Power, C., Kong, P., Crawford, T.O., Wesselingh, S., Glass, J.D., McArthur, J.C. and Trapp, B.D. (1993) Cerebral white matter changes in acquired immunodeficiency syndrome. Ann. Neurol., 34: 339-350.
108. Quinlivan, E.B., Norris, M., Bouldin, T.W., Suzuki, K., Meeker, R., Smith, M.S., Hall, C. and Kenney, S. (1992) Subclinical central nervous system infection with JC virus in patients with AIDS. J. Infect. Dis., 166: 80-85.
109. Racaniello, V.R. (1990) Cell receptors for picornaviruses. Curr. Top. Microbiol. Immunol., 161: 1-22.
110. Raj, G.V. and Khalili, K. (1994) Identification and characterization of a novel GGA/C-binding protein, GPB-i, that is rapidly inducible by cytokines. Mol. Cell Biol., 14: 7770-7781.
111. Raj, G.V. and Khalili, K. (1995) Transcriptional regulation: Lessons from the human neurotropic polyomavirus, JCV. Virology, 213: 283-291.
112. Raj, G.V., Safak, M., MacDonald, G.H. and Khalili, K. (1996) Transcriptional regulation of human polyomavirus, JC: Evidence for a functional interaction between RelA (p65) and the Y-box binding protein, YB-1. J. Virol., 70: 5944-5953.
113. Ranki, A., Nyberg, M. and Ovod, V. (1995) Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia. AIDS, 9: 1001-1008.
114. Rencic, A., Gordon, J., Otte, J., Curtis, M., Kovatich, A., Zoltick, P., Khalili, K. and Andrews, D. (1996) Detection of JC virus DNA sequence and expression of the viral oncoprotein, tumor antigen, in brain of immunocompetent patient with oligoastrocytoma. Proc. Natl. Acad. Sci. USA, 93: 7352-7357.
115. Ricci, L., Maione, R., Passananti, C., Felsani, A. and Amati, P. (1992) Mutations in the VP1 coding region of polyomavirus determine. J. Virol., 66: 7153-7158.
116. Rizzuto, C.D., Wyatt, R., Hernandez-Ramos, N., Sun, Y., Kwong, P.D., Hendrickson, W.A. and Sodroski, J. (1998) A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding. Science, 280: 1949-1953.
117. Sabri, F., Tresoldi, E., Di Stefano, M., Polo, S., Monaco, M.C., Verani, A., Fiore, J.R., Lusso, P., Major, E., Chiodi, F. and Scarlatti, G. (1999) Nonproductive human immunodeficiency virus type 1 infection of human fetal astrocytes: Independence from CD4 and major chemokine receptors. Virology, 264: 370-384.
118. Safak, M., Gallia, G.L. and Khalili, K. (1999) Reciprocal interaction between two cellular proteins, Puralpha and YB-1, modulates transcriptional activity of JCVCY in glial cells. Mol. Cell Biol., 19: 2712-2723.
119. Sahli, R., Freund, R., Dubensky, T., Garcea, R., Bronson, R. and Benjamin, T. (1993) Defect in entry and altered pathogenicity of a polyoma virus mutant blocked in VP2 myristylation. Virology, 192: 142-153.
120. Shieh, J.T.C., Albright, A.V., Sharron, M., Gartner, S., Strizki, J., Doms, R.W. and Gonzalez-Scarano, F. (1998) Chemokine receptor utilization by human immunodeficiency virus type 1 isolates that replicate in microglia. J. Virol., 72: 4243-4249.
121. Soontornniyomkij, V., Nieto-Rodriguez, J.A., Martinez, A.J., Kingsley, L.A., Achim, C.L. and Wiley, C.A. (1998) Brain HIV burden and length of survival after AIDS diagnosis. Clin. Neuropathol., 17: 95-99.
122. Stang, E., Kartenbeck, J. and Parton, R.G. (1997) Major histocompatibility complex class I molecules mediate association of SV40 with caveolae. Mol. Biol. Cell, 8: 47-57.
123. Stehle, T., Yan, Y., Benjamin, T.L. and Harrison, S.C. (1994) Structure of murine polyomavirus complexed with an oligosaccharide receptor fragment. Nature, 369: 160-163.
124. Sumner, C., Shinohara, T., Durham, L., Traub, R., Major, E. and Amemiya, K. (1996) Expression of multiple classes of the nuclear factor-1 family in the developing human brain: Differential expression of two classes of NF-1 genes. J. Neurovirol., 2: 87-100.
125. Tomassini, J.E., Graham, D., DeWitt, C.M., Lineberger, D.W., Rodkey, J.A. and Colonno, R.J. (1989) cDNA cloning reveals that the major group rhinovirus receptor on HeLa cells in intercellular adhesion molecule 1. Proc. Natl. Acad. Sci. USA, 86: 4907-4911.
126. Tornatore, C.S., Nath, A., Amemiya, K. and Major, E.O. (1991) Persistent human immunodeficiency virus type 1 infection in human glial cells reactivated by T cell factors or by the cytokines tumor necrosis factor alpha and interleukin 1 beta. J. Virol., 65: 6094-6100.
127. Tornatore, C., Nath, A., Amemiya, K. and Major, E.O. (1993) Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-1 beta. J. Virol., 65: 6094-6100.
128. Tornatore, C., Amemiya, K., Atwood, W., Conant, K., Major, E.O. and Berger, J. (1994a) JC virus - Current concepts and controversies in the molecular virology and pathogenesis of progressive multifocal leukoencephalopathy. Rev. Med. Virol., 4: 197-219.
129. Tornatore, C., Chandra, R., Berger, J.R. and Major, E.O. (1994b) HIV-1 infection of subcortical astrocytes in the pediatric central nervous. Neurology, 44: 481-487.
130. Tornatore, C., Meyers, K., Atwood, W., Conant, K. and Major, E. (1994c) Temporal patterns of human immunodeficiency virus type 1 transcripts in human fetal astrocytes. J. Virol., 68: 93-102.
131. Vago, L., Cinque, P., Sala, E., Nebuloni, M., Caldarelli, R., Racca, R., Ferrante, P., Trabattoni, G. and Costanzi, G. (1996) JCV-DNA and BKV-DNA in the CNS tissue and CSF of AIDS patients and normal subjects. Study of 41 cases and review of the literature. J. Acquired Immune Defic. Syndr. Hum. Retrovirol., 12: 139-146.
132. Walker, D.L. and Frisque, R.J. (1986) The biology and molecular biology of JC virus. In: N.P. Salzman (Ed.), The Papovaviridae. Plenum Press, New York, pp. 327-377.
133. Watkins, B.A., Dorn, H.H., Kelly, W.B., Armstrong, R.C., Potts, B.J., Michaels, F., Kufta, C.V. and Dubois-Dalcq, M. (1990) Specific tropism of HIV-1 for microglial cells in primary human brain cultures. Science, 249: 549-552.
134. Wei, G., Liu, C.K. and Atwood, W.J. (2000) JC virus binds to primary human glial cells, tonsillar stromal cells, and B-lymphocytes, but not to T-lymphocytes. J. Neurovirol., 6: 127-136.
135. Weiss, R.A. and Tailor, C.S. (1995) Retrovirus receptors. Cell, 82: 531-533.
136. Wiley, C., Schrier, R., Nelson, J., Lampert, P. and Oldstone, M. (1986) Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency patients. Proc. Natl. Acad. Sci. USA, 83: 7089-7093.
137. Willoughby, R.E., Yolken, R.H. and Schnaar, R.L. (1990) Rotaviruses specifically bind to the neutral glycosphingolipid asialo-GM1. J. Virol., 64: 4830-4835.
138. Wyatt, R., Kwong, P.D., Desjardins, E., Sweet, R., Robinson, J., Hendrickson, W.A. and Sodroski, J. (1998) The antigenic structure of HIV gp120 envelope protein. Nature, 393: 705-711.
139. Yu, N., Billaud, J.N. and Phillips, T.R. (1998) Effects of feline immunodeficiency virus on astrocyte glutamate uptake: Implications for lentivirus-induced central nervous system diseases. Proc. Natl. Acad. Sci. USA, 95: 2624-2629.