Predictive markers of AIDS dementia complex: CD4 cell count and cerebrospinal fluid concentrations of β2-microglobulin and neopterin

Journal of Infectious Diseases

Volumn 174, Issue 2, 1996, Pages 294-298

  Brew, Bruce James ^a   Dunbar, Nicola ^b   Pemberton, Louise ^b   Kaldor, John ^b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; CD4 ANTIGEN; NEOPTERIN;

ADULT; ARTICLE; CEREBROSPINAL FLUID LEVEL; CLINICAL ARTICLE; CLINICAL TRIAL; FOLLOW UP; HIGH RISK PATIENT; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; PRACTICE GUIDELINE; PREDICTION; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0029892999     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/174.2.294     Document Type: Article

References (18)

1. Report of a Working Group of the American Academy of Neurology AIDS Task Force. Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus type 1 (HIV-1) infection. Neurology 1991;41:778-85.
2. Sidtis JJ, Gatsonis C, Price RW, et al. Zidovudine treatment of the AIDS dementia complex: results of a placebo controlled trial. Ann Neurol 1993;33:343-49.
3. McArthur JC, Hoover DR, Bacellar H, et al. Dementia in AIDS patients: incidence and risk factors. Neurology 1993;43:2245-52.
4. Price RW, Brew BJ. The AIDS dementia complex. J Infect Dis 1988;158:1079-83.
5. Portegies P. HIV-1, the brain and combination therapy. Lancet 1996;346:1244-5.
6. 2 microglobulin in patients infected with human immunodeficiency virus. Neurology 1989;39:830-4.
7. 2-microglobulin levels in blood and cerebrospinal fluid occur early in HIV 1 infection. AIDS 1989;3:277-83.
8. 2-microglobulin in patients with AIDS dementia complex: an expanded series including response to zidovudine treatment. AIDS 1992;6:461-5.
9. Brew BJ, Bhalla RB, Fleisher M, et al. Cerebrospinal fluid neopterin in human immunodeficiency virus type-1 infection. Ann Neural 1990;28:556-60.
10. Fuchs D, Chiodi F, Albert J, et al. Neopterin concentrations in cerebrospinal fluid and serum of individuals infected with HIV-1. AIDS 1989;3:285-8.
11. 2-microglobulin in HIV-1 dementia. Neurology 1992;42:1707-12.
12. + T cell count, in vitro T helper cell function, and spinal fluid IgG parameters in 163 neurologically normal adults infected with the human immunodeficiency virus type 1. J Infect Dis 1991;163:971-5.
13. Price RW, Sidtis JJ. Evaluation of the AIDS dementia complex in clinical trials. J AIDS 1990;3(suppl):S51-60.
14. Glass JD, Wesselingh SL, Seines OA, McArthur JC. Clinical-neuropathologic correlation in HIV-associated dementia. Neurology 1993;43:2230-7.
15. Brew BJ, Rosenblum M, Cronin K, Price RW. The AIDS dementia complex and human immunodeficiency virus type 1 brain infection: clinical-virological correlations. Ann Neurol 1995;38:563-70.
16. Epstein LG, Gendelman HE. Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms. Ann Neurol 1993;33:429-36.
17. Kure K, Weidenheim KM, Lyman WD, Dickson DW. Morphology and distribution of HIV-1 gp41-positive microglia in subacute AIDS encephalitis. Acta Neuropathol 1990;80:393-400.
18. Harouse JM, Wroblewska Z, Laughlin M, et al. Human choroid plexus cells can be latently infected with human immunodeficiency virus. Ann Neurol 1989;25:406-11.