Transcriptional regulation of human polyomavirus JC: Evidence for a functional interaction between RelA (p65) and the Y-box-binding protein, YB- 1

Journal of Virology

Volumn 70, Issue 9, 1996, Pages 5944-5953

  Raj, Ganesh V ^a   Safak, Mahmut ^a   Macdonald, Gene H ^b   Khalili, Kamel ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN;

ACUTE PHASE RESPONSE; ARTICLE; BINDING AFFINITY; DNA BINDING; GENETIC REGULATION; NONHUMAN; POLYOMA VIRUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; TRANSCRIPTION REGULATION; VIRUS CELL INTERACTION; VIRUS GENOME;

EID: 0029813733     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.9.5944-5953.1996     Document Type: Article

References (52)

1. E: identification of a novel activator domain located upstream from the 98 bp enhancer promoter region. Nucleic Acids Res. 18:7417-7423.
2. Askamit, A., and J. Proper. 1988. JC virus replicates in primary adult astrocytes in culture. Ann. Neurol. 24:471.
3. Astrom, K. E., E. L. Mancall, and E. P. Richardson. 1958. Progressive multifocal leukoencephalopathy. Brain 81:93-127.
4. Baeuerle, P. A., and T. Henkel. 1994. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12:141-179.
5. Beg, A. A., and A. S. Baldwin, Jr. 1993. The I kappa B proteins: multifunctional regulators of rel/NF-kappa B transcription factors. Genes Dev. 7:2064-2070.
6. Bressler, P., K. Brown, W. Timmer, V. Bours, U. Siebenlist, and A. S. Fauci. 1993. Mutational analysis of the p50 subunit of NF-κB and inhibition of NF-κ B activity by trans-dominant p50 mutants. J. Virol. 67:288-293.
7. Chen, N. N., C. F. Chang, G. L. Gallia, D. A. Kerr, E. M. Johnson, C. P. Krachmarov, S. M. Barr, R. J. Frisque, B. Bollas, and K. Khalili. 1995. Cooperative action of cellular proteins YB-1 and Purα with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control element. Proc. Natl. Acad. Sci. USA 92:1087-1091.
8. Coleman, T. A., C. Kunsch, M. Maher, S. M. Ruben, and C. A. Rosen. 1993. Acquisition of NF-κB1-selective DNA binding by substitution of four amino acid residues from NF-κB1 into Re1A. Mol. Cell. Biol. 13:3850-3859.
9. Didier, D., J. Schiffenbauer, S. Woulfe, M. Zacheis, and B. Schwartz. 1988. Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box. Proc. Natl. Acad. Sci. USA 85: 7322-7326.
10. Diehl, J. A., W. Tong, G. Sun, and M. Hannink. 1995. Tumor necrosis factor-alpha-dependent activation of a ReIA homodimer in astrocytes-increased phosphorylation of ReIA and mad-3 precede activation of Re1A. J. Biol. Chem. 270:2703-2707.
11. Dignam, J. D., R. M. Lebowitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
12. Dobrzanski, P., R. P. Ryseck, and R. Bravo. 1994. Differential interactions of rel-NF-κB complexes with 1κBa determine pools of constitutive and inducible NF-κB activity. EMBO J. 13:4608-4616.
13. Evdokimova, V. M., C.-L. Wei, A. S. Sitikov, P. N. Simenenko, O. A. Lazarev, K. S. Vasilenko, V. A. Ustinov, J. W. B. Hershey, and L. P. Ovchinnikov. 1995. The major protein of messenger ribonucleoprotein particles in somatic cells is a member of the Y-box binding transcription factor family. J. Biol. Chem. 270:3186-3192.
14. Frisque, R. J., and F. A. White. 1992. The molecular biology of JC virus, causative agent of progressive multifocal leukoencephalopathy, p. 25-158. In R. P. Roos (ed.), Molecular Neurovirology. Humana Press, Towana, N.J.
15. Fujita, T., G. P. Nolan, S. Ghosh, and D. Baltimore. 1992. Independent modes of transcriptional activation by the p50 and p65 subunits of NF-κB. Genes Dev. 6:775-787.
16. Ganchi, P. A., S. Sun, W. C. Greene, and D. W. Ballard. 1993. A novel NF-κB complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization. Mol. Cell. Biol. 13:7826-7835.
17. Gilmore, T. D., and P. J. Morin. 1993. The IκB proteins: members of a multifunctional family. Trends Genet. 9:427-433.
18. Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044-1051.
19. Graham, F. L., and A. J. van der Eb. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52:456-467.
20. Grimm, S., and P. A. Baeuerle. 1993. The inducible transcription factor NF-κB structure-function relationship of its protein subunits. Biochemistry 290:297-308.
21. Kerr, D., C.-F. Chang, N. N. Chen, G. Gallia, G. Raj, B. Schwartz, and K. Khalili. 1994. Transcription of a human neurotropic virus promoter in glial cells: effect of YB-1 on expression of JC viral late gene. J. Virol. 68:7637-7643.
22. Kerr, L. D., L. J. Ransone, P. Wamsley, M. J. Schmitt, T. G. Boyer, Q. Zhou, A. J. Berk, and I. Verma. 1993. Association between protooncoprotein rel and TATA-binding protein mediates transcriptional activation by NF-κB. Nature (London) 365:412-419.
23. Kolluri, R., T. Torrey, and A. Kinniburgh. 1992. A CT promoter element binding protein: definition of a double stranded and a novel single stranded DNA binding motif. Nucleic Acids Res. 20:111-116.
24. Kunsch, C., S. M. Ruben, and C. A. Rosen. 1992. Selection of optimal κB/Rel DNA-binding motifs: interaction of both subunits of NF-κB with DNA is required for transcriptional activation. Mol. Cell. Biol. 12:4412-4421.
25. LeClair, K. P., M. A. Blanar, and P. A. Sharp. 1992. The p50 subunit of NF-κB associates with the NF-IL6 transcription factor. Proc. Natl. Acad. Sci. USA 89:8145-8149.
26. Lernbecher, T., U. Muller, and T. Wirth. 1993. Distinct NF-κB/rel transcription factors are responsible for tissue-specific and inducible gene activation. Nature (London) 365:767-770.
27. Major, E. O., K. Amemiya, C. S. Tornatore, S. A. Houff, and J. R. Berger. 1992. Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy. the JC virus-induced demyelinating disease of the human brain. Clin. Microbiol. Rev. 5:49-73.
28. Mayreddy, R. P. R., et al. Unpublished data.
29. Murakami, T., H. Hirai, T. Suzuki, J.-I. Fujisawa, and M. Yoshida. 1995. HTLV-1 Tax enhances NF-κB2 expression and hinds to the products p52 and p100, but does not suppress the inhibitory function of p100, Virology 206:1066-1074.
30. Padgett, B. L., D. L. Walker, G. M. Zu Rhein, R. J. Eckroade, and B. H. Dessel. 1971. Cultivation of a papova-like virus from human brain with progressive multifocal leukoencephalopathy. Lancet i:1257-1260.
31. Perkins, N. D., R. M. Schmid, C. S. Duckett, K. Leung, N. R. Rice, and G. J. Nabel. 1992. Distinct combinations of NF-κB subunits determine the specificity of transcriptional activation. Proc. Natl. Acad. Sci. USA 89:1529-1533.
32. Raj, G. V., and K. Khalili. 1994. A novel rapidly inducible GGA/C-binding factor, GBP-i. regulates transcription from the JC virus promoter. Mol. Cell. Biol. 14:7770-7781.
33. Raj, G. V., et al. Unpublished data.
34. Ranganathan, P., and K. Khalili. 1993. The transcriptional enhancer element, κB, regulates promoter activity of the human neurotropic virus, JCV, in cells derived from the CNS. Nucleic Acids Res. 21:1959-1964.
35. Ray, A., and K. E. Prefontaine. 1994. Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor. Proc. Natl. Acad. Sci. USA 91:752-756.
36. Ruben, S. M., J. F. Klement, T. A. Coleman, M. Maher, C.-H. Chen, and C. A. Rosen. 1992. I-rel: a novel rel-related protein that inhibits NF-κB transcriptional activity. Genes Dev. 6:745-760.
37. Schmid, R. M., S. Liptay, J. C. Betts, and G. J. Nabel. 1994. Structural and functional analysis of NF-kappa B. Determinants of DNA binding specificity and protein interaction. J. Biol. Chem. 269:32162-32167.
38. Schmid, R. M., N. D. Perkins, C. S. Duckett, P. C. Andrews, and G. J. Nabel. 1991. Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65. Nature (London) 352:733-756.
39. Schmitz, M. L., and P. A. Baeuerle. 1991. The p65 subunit is responsible for the strong transcription activating potential of NF-κB. EMBO J. 10:3805-3817.
40. Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffner. 1989 Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res. 17:6419.
41. Sher, A., R. T. Gazzinelli, I. P. Oswald, M. Clerici, M. Kullberg, E. J. Pearce, J. A. Berzofsky, T. R. Mosmann, S. L. James, H. L. Morse, and G. M. Shearer. 1992. Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infections. Immunol. Rev. 127: 183-219.
42. Siebenlist, U., G. Franzoso, and K. Brown. 1994. Structure, regulation, and function of NF-κB. Annu. Rev. Cell Biol. 10:405-456.
43. Stein, B., A. S. Baldwin, Jr., D. W. Ballard, W. C. Greene, P. Angel, and P. Herrlich. 1993. Cross-coupling of the NF-κB p65 and Fos/Jun transcription factors produces potentiated biological function. EMBO J. 12:3879-3891.
44. Stein, B., P. C. Cogswell, and A. S. Baldwin, Jr. 1993. Functional and physical associations between NF-κB and C/EBP family members: a Rel domain-bZIP interaction. Mol. Cell. Biol. 13:3964-3974.
45. Thanos, D., and T. Maniatis. 1995. NF-κB: a lesson in family values. Cell 80:529-532.
46. Ting, J. P., A. Painter, N. J. Zeleznik-Le, G. MacDonald, T. M. Moore, A. Brown, and B. D. Schwartz. 1994. YB-1 DNA-binding protein represses Interferon gamma activation of class II major histocompatibility complex genes. J. Exp. Med. 179:1605-1611.
47. Tornatore, C., A. Nath, K. Amemiya, and E. O. Major. 1991. Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by cytokines tumor necrosis factor alpha and interleukin-1β. J. Virol. 65:6094-6100.
48. Walker, D. L., and B. L. Padgett. 1983. The epidemiology of human papovaviruses, p. 99-106. In J. L. Sever and D. L. Madden (ed.), Polyomaviruses and human neurological diseases. Alan R. Liss. Inc., New York.
49. Wolffe, A. 1994. Structural and functional properties of the evolutionarily ancient Y-box family of nucleic acid binding proteins. Bioessays 16:245-251.
50. Wolffe, A., S. Tafuri, M. Ranjan, and M. Familari. 1992. The Y-box factors: a family of nucleic acid binding proteins conserved from Escherichia coli to man. New Biol. 4:290-298.
51. Xu, X., C. Prorock, H. Ishikawa, E. Maldonado, Y. Ito, and C. Gelinas. 1993. Functional interaction of the v-rel and c-rel oncoproteins with the TATA-binding protein and association with transcription factor IIb. Mol. Cell. Biol. 13:6733-6741.
52. Zhang, J., C. C. Chang, L. Lombardi, and R. Dalla-Favera. 1994. Rearranged NFKB2 gene in the HUT78 T-lymphoma cell line codes for a constitutively nuclear factor lacking transcriptional repressor functions. Oncogene 9:1931-1937.