Progressive multifocal leukoencephalopathy

Seminars in Neurology

Volumn 19, Issue 2, 1999, Pages 193-200

  Berger, Joseph R ^a,c   Major, Eugene O ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Highly active antiretroviral therapy; JC virus; Progressive multifocal leukoencephalopathy

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; DEMYELINATING DISEASE; HISTOPATHOLOGY; HUMAN; JC VIRUS; LYMPHOCYTE COUNT; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; POPULATION RESEARCH; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; REVIEW; SEROEPIDEMIOLOGY; SURVIVAL;

EID: 0032833054     PISSN: 02718235     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1040837     Document Type: Review

References (89)

1. Hallervorden J. Eigennartige und nicht rubriziebare Prozesse.In: Bumke O, ed. Handbuch der Geiteskranheiten. Vol. 2. Die Anatomie der Psychosen. Berlin: Springer, 1930:1063-1107
2. Åstrorn KE, Mancall EL, Richardson EP Jr. Progressive multifocal leukoencephalopathy. Brain 1958;81:93-127
3. Cavanaugh JB, Greenbaum D, Marshall A, et al. Cerebral demyelination associated with disorders of reticuloendothelial system. Lancet 1959;2:524-529
4. ZuRhein GM. Polyoma-like virions in a human demyelinating disease. Acta Neuropathol 1967;8:57-68
5. ZuRhein GM. Association of papovavirions with a human demyelinating disease (progressive multifocal leukoencephalopathy). Prog Med Virol 1969;11:185-247
6. Padgett BL, ZuRhein G, Walker D, et al. Cultivation of papovalike virus from human brain with progressive multifocal leukoencephalopathy. Lancet 1971;1:1257-1260
7. London WT, Houff SA, Madden DL. et al. Brain tumors in owl monkeys inoculated with a human polyomavirus (JC virus). Science 1978;201:1246-1249
8. London WT, Houff SA, McKeever PE. et al. Viral-induced astrocytomas in squirrel monkeys. Prog Clin Biol Res 1982;105:227-237
9. Major EO, Vacante DA, Traub TG, et al. Owl monkey astrocytoma cells in culture spontaneously produce infectious JC Virus which demonstrates altered biological properties. J Virol 1987;53:306-311
10. Padgett BL, Walker DL, ZuRhein GM, et al. Differential neurooncogenicity of strains of JC virus, a human polyoma virus, in newborn Syrian hamsters. Cancer Res 1977;37:718-720
11. Walker DL, Padgett BL, ZuRhein GM, et al. Human papovavirus (JC): Induction of brain tumors in hamsters. Science 1973;181: 674-676
12. Stoner GL, Ryschkewitsch CF, Walker DL, et al. JC papovavirus large tumor (T)-antigen expression in brain tissue of acquired immune deficiency syndrome (AIDS) and non-AIDS patients with progressive multifocal leukoencephalopathy. Proc Natl Acad Sci USA 1986;23:2271-2275
13. Jobes DV, Chima SV, Ryschkewitsch CF, et al. Phylogenetic analysis of 22 complete genomes of the human polyomavirus JC virus. J Gen Virol 1998;79:2491-2498
14. Atwood W, Amemiya K, Traub R, et al. Interactions of the human polyomavirus, JCV, with human B lymphocytes. Virology 1992; 190:716-723
15. Liu CK, Wei G, Atwood WJ. Infection of glial cells by the human polyomavirus JC is mediated by an N-linked glycoprotein containing terminal α(2-6)-linked sialic acids. J Virol 1998;72: 4643-4649
16. Frisque RJ, Martin JD, Padgett BL, et al. Infectivity of the DNA from four isolates of JCV. J Virol 1979;32:476-482
17. Frisque R, Bream G, Cannella M. Human polyomavirus JC virus genome. J Virol 1984;51:458-469
18. Khalili E, Rappaport J, Khoury G. Nuclear factors in human brain cells bind specifically to the JCV regulatory region. EMBO J 1988;7:1205-1210
19. Vacante DA, Traub R, Major EO. Extension of JC virus host range to monkey cells by insertion of a simian virus 40 enhancer into the JC virus regulatory region. Virology 1988;170:353-361
20. Dorries K. Progressive multifocal leukoencephalopathy: Analysis of JC virus DNA from brain and kidney tissue. Virus Res 1984;1:25-38
21. Martin JD, King DM, Slauch JM, et al. Differences in regulatory sequences of naturally occurring JC virus variants. J Virol 1985; 53:306-311
22. Feigenbaum L, Khalili K, Major EO, et al. Regulation of the host range of human papovavirus JCV Proc Natl Acad Sci USA 1987;84:3695-3698
23. Major EO, Amemiya EE, Tornatore CS, et al. Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JV virus-induced demyelinating disease of the human brain. Clin Microbiol 1992;5:49-73
24. Rhiza HJ, Bornkamm G, ZurHausen H. Seroepidemiological studies and serologic response to viral infection. Med Microbiol Immunol 1978;165:73-92
25. Walker DL, Padgett BL. The epidemiology of human polyomaviruses. In Sever JL, Madden D, eds. Polyomaviruses and human neurological disease. New York: Alan R. Liss, 1983:99-106
26. Monaco MCG, Jensen PN, Hou J, et al. Detection of JC virus DNA in human tonsil tissue: Evidence for site of initial viral infection. J Virol 1998;72:9918-9923
27. Tornatore C, Berger JR, Houff SA, et al. Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathy. Ann Neurol 1992; 31:454-462
28. White FA, Ishaq M, Stoner GL, et al. JC virus DNA is present in many human brain samples from patients without progressive multifocal leukoencephalopathy. J Virol 1992;66:5726-5734
29. Buckle GJ, Godec MS, Rubi JU, et al. Lack of JC viral genomic sequences in multiple sclerosis brain tissue by polymerase chain reaction. Ann Neurol 1992;32(6):829-831
30. Perrons C, Fox J, Lucas S, et al. Detection of polyomaviral DNA in clinical samples from immunocompromised patients: Correlation with clinical disease. J Infect 1996;32:205-209
31. Major EO, Amemiya K, Elder G, et al. Glial cells of the human developing brain and B cells of the immune system share a common DNA binding factor for recognition of the regulatory sequences of the human polyomavirus, JCV. J Neurosci Res 1990;27:461-471
32. Atwood WJ, Amemiya K, Traub R, et al. Interaction of the human polyomavirus. JCV, with human B-lymphocytes. Virology 1992;190:716-723
33. Sumner C, Shinohara T, Durham L, et al. Expression of multiple classes of the nuclear factor-1 family in the developing human brain: differential expression of two classes of NF-1 genes. J Neurovirol 1996;2:87-100
34. Shinohara T, Nagashima K, Major EO. Propagation of the human polyomavirus, JCV, in human neuroblastoma cell lines. Virology 1997;228:269-277
35. Raj GV, Khalili K. Transcriptional regulation: Lessons from the human neurotropic polyomavirus, JCV. Virology 1995;213(2): 283-291
36. Willoughby E, Price RW, Padgett BL, et al. Progressive multifocalleukoencephalopathy (PML): In vitro cellmediated immune responses to mitogens and JC virus. Neurology 1980;30: 256-262
37. Brooks BR, Walker DL. Progressive multifocal leukoencephalopathy. Neurol Clin 1984;2:299-313
38. Berger JR, Pall L, Lanska D, et al. Progressive multifocal leukoencephalopathy in patients with HIV infection. J Neurovirol 1998;4:59-68
39. Katz DA, Berger JR, Hamilton B, et al. Progressive multifocal leukoencephalopathy complicating Wiskott-Aldrich syndrome. Arch Neurol 1994;51:422-426
40. Miller J, Barrett R, Britton C. Progressive multifocal leukoencephalopathy in a male homosexual with T-cell immune deficiency. N Engl J Med 1982;307:1436-1438
41. Krupp LB, Lipton RB, Swerdlow ML, et al. Progressive multifocal leukoencephalopathy: Clinical and radiographic features. Ann Neurol 1985;17:344-349
42. Berger JR, Kaszovitz B, Post JD, et al. Progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection: A review of the literature and report of 16 cases. Ann Intern Med 1987;107:78-87
43. Gillespie SM, Chang Y, Lemp G, et al. Progressive multifocal leukoencephalopathy in persons infected with human immunodeficiency virus, San Francisco, 1981-1989. Ann Neurol 1991;30:597-604
44. Holman RC, Janssen RS, Buehler JW, et al. Epidemiology of progressive multifocal leukoencephalopathy in the United States: Analysis of national mortality and AIDS surveillance data. Neurology 1991;41:1733-1736
45. Messite J, Stellman SD. Accuracy of death certificate completion. JAMA 1996;275:794-796
46. Lang W, Miklossy J, Deruaz JP, et al. Neuropathology of the acquired immune deficiency syndrome (AIDS): A report of 135 consecutive autopsy cases from Switzerland. Acta Neuropathol 1989;77:379-390
47. Kure K, Llena JF, Lyman WD, et al. Human immunodeficiency virus1 infection of the nervous system: An autopsy study of 268 adult, pediatric and fetal brains. Hum Pathol 1991:22:700-710
48. Kuchelmeister K, Gullotta F. Bergmann M, et al. Progressive multifocal leukoencephalopathy (PML) in the acquired immunodeficiency syndrome (AIDS). A neuropathological autopsy study of 21 cases. Path Res Pract 1993;189:163-173
49. Whiteman M, Post MJD, Berger JR, et al. PML in 47 HIV+ patients. Radiology 1993;187:233-240
50. Bacellar H, Munoz A, Miller EN, et al. Temporal trends in the incidence of HIV-1 -related neurologic disease: Multi-center AIDS Cohort Study, 1985-1992. Neurology 1994 44:1892-1900
51. Houff SA, Major EO, Katz D, et al. Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy. N Engl J Med 1983;318:301-305
52. Power C, Kong PA, Crawford TO, et al. Cerebral white matter changes in acquired immunodeficiency syndrome dementia: Alteration of the blood-brain-barrier. Ann Neurol 1993;34: 339-350
53. Hofman FM, Dohadwala MM, Wright AD, et al. Exogenous tat protein activates central nervous system-derived endothelial cells. J Neuroimmunol 1994;54:19-28
54. Sasseville VG, Newman WA, Lackner AA, et al. Elevated vascular cell adhesion molecule-1 in AIDS encephalitis induced by simian immunodeficiency virus. Am J Pathol 1992;141:1021-1030
55. Tada H, Rappaport J, Lashgari M, et al. Trans-activation of the JC virus late promoter by the Tat protein of the type 1 human immunodeficiency virus in glial cells. Proc Natl Acad Sci USA 1990;87:3479-3483
56. Sweeney BJ, Manji H, Miller RF, et al. Cortical and subcortical JC virus infection: two unusual cases of AIDS associated progressive multifocal leukoencephalopathy. J Neurol Neurosurg Psychiatry 1994;57:994-997
57. Wong MC, Suite ND, Labar DR. Seizures in human immunodeficiency virus infection. Arch Neurol 1990;47:640-642
58. Omerud LD, Rhodes RH, Gross SA, et al. Opthalmologic manifestations of acquired immune deficiency syndrome-associated progressive multifocal leukoencephalopathy. Ophthalmology 1996;103:899-906
59. Fong IW, Toma E. The natural history of progressive multifocal leukoencephalopathy in patients with AIDS Canadian PML Study Group. Clin Infect Dis 1995;20:1305-1310
60. von Einsiedel RW, Fife TD, Aksamit AJ, et al. Progressive multifocal leukoencephalopathy in AIDS: A clinicopathological study and review of the literature. J Neurol 1993;240:391-406
61. Marshall DW, Brey RL, Cahill WT, et al. Spectrum of cerebrospinal fluid findings in various stages of human immunodeficiency virus infection. Arch Neurol 1988;45:954-958
62. Katz RL, Alappattu C, Glass JP, et al. Cerebrospinal fluid manifestations of the neurologic complications of human immunodeficiency virus infection. Acta Cytol 1989;33:233-244
63. Elovaara I, Iivanainen M, Valle S-L, et al. CSF protein and cellular profiles in various stages of HIV infection related to neurological manifestations. J Neurol Sci 1987;78:331-342
64. Weber T, Turner RW, Frye S, et al. Progressive multifocal leukoencephalopathy diagnosed by amplification of JC virus-specific DNA from cerebrospinal fluid. AIDS 1994;8:49-57
65. Fong IW, Britton CV, Luinstra KK, et al. Diagnostic value of detecting JC virus DNA in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy. J Clin Microbiol 1995;33:484-486
66. McGuire D, Barhite S, Hollander H, et al. JC virus DNA in cerebrospinal fluid of human immunodeficiency virus-infected patients: Predictive value for progressive multifocal leukoencephalopathy. Ann Neurol 1995;37:395-399
67. Major EO, Curfman BL. Viral-induced demyelination leading to progressive multifocal leukoencephalopathy: The involvement of both immune and nervous system target cells. In: Remington J, Peterson PK, eds. Defense of the brain. Cambridge, MA: Blackwell Science, 1997:305-321
68. Richardson EP Jr. Progressive multifocal leukoencephalopathy. In: Vinken PJ, Bruyn GW, eds. Handbook of clinical neurology. Vol. 9. Multiple sclerosis and other demyelinating diseases. New York: Elsevier, 1970:485-499
69. Mazlo M, Herndon RM. Progressive multifocal leukoencephalopathy: Ultrastructural findings in two brain biopsies. Neuropathol Appl Neurobiol 1977;3:323-339
70. Mazlo M, Tariska I. Are astrocytes infected in progressive multifocal leukoencephalopathy. Acta Neuropathol (Berl.) 1982;56: 45-51
71. Berger JR, Levy RM, Flomenhoft D, et al. Predictive factors for prolonged survival in acquired immunodeficiency syndrome-associated progressive multifocal leukoencephalopathy. Ann Neurol 1998;44:341-349
72. Taoufik Y, Gasnault J, Karaterki A, et al. Prognostic value of JC virus load in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy. J Infect Dis 1998;178;1816-1820
73. Koralnik IJ, Boden D, Mai VX, et al. JC virus DNA load in patients with and without progressive multifocal leukoencephalopathy. Neurology 1999;52:253-260
74. Yiannoutsos C, Major EO, Curfman B, et al. Relation of JC virus DNA in the CSF to survival in AIDS patients with biopsy proven progressive multifocal leukoecephalopathy. Ann Neurol (in press)
75. Bauer WR, Turel AP Jr, Johnson KP. Progressive multifocal leukoencephalopathy and cytarabine: Remission with treatment. JAMA 1973;226:174-176
76. Singer EJ, Stoner GL, Singer P, et al. AIDS presenting as progressive multifocal leukoencephalopathy with clinical response to zidovudine. Acta Neurol Scand 1994;90:443-447
77. Conway B, Halliday WC, Brunham RE. Human immunodeficiency virus-associated progressive multifocal leukoencephalopathy: apparent response to 3′-azido-3′-deoxythymidine. Rev Infect Dis 1990;12:479-482
78. Martin-Suarez I, Aguayo Canela M, Merino Munoz D, et al. Prolonged survival in patients with progressive multifocal leukoencephalopathy associated with AIDS treated with high doses of zidovudine [letter]. Rev Clin Esp 1994;194:136-138
79. Fiala M, Cone LA, Cohen N, et al. Responses of neurologic complications of AIDS to 3′-azido-3′-deoxythymidine and 9-(1,3-dihydroxy-2-propoxymethyl) luanine. I. Clinical features. Rev Infect Dis 1988;10:250-256
80. Albrecht H, Hoffmann C, Degen O, et al. Highly active antiretroviral therapy significantly improves the prognosis of patients with HIV-associated progressive multifocal leukoencephalopathy. AIDS 1998;9:1149-1154
81. Conomy JP, Beard NS, Matsumoto H, et al. Cytarabine treatment of progressive multifocal leukoencephalopathy. JAMA 1974; 229:1313-1316
82. Buckman R, Wiltshaw E. Progressive multifocal leukoencephalopathy successfully treated with cytosine arabinoside. Br J Haematol 1976;34:153-1554
83. Peters ACB, Versteeg J, Bots GTA, et al. Progressive multi-focal leukoencephalopathy: Immunofluorescent demonstration of SV40 antigen in CSF cells and response to cytarabine therapy. Arch Neurol 1980;37: 497-501
84. O'Riordan T, Daly PA, Hutchinson M, et al. Progressive multifocal leukoencephalopathy - remission with cytarabine. J Infect Dis 1990;20:51-54
85. Portegies P, Algra PR, Hollar CEM, et al. Response to cytarabine in progressive multifocal leukoencephalopathy in AIDS. Lancet 1991;337:680-681
86. Hou J, Major EO. The efficacy of nucleoside analogs against JC virus multiplication in a persistently infected human fetal brain cells line. J Neurovirol 1998;4:451-456
87. Hall CD, Dafni U, Simpson D, et al. Failure of cytosine arabinoside therapy for human immunodeficiency virus-1 associated progressive multifocal leukoen-cephalopathy: ACTG 243. N Engl J Med 1998;338:1345-1351
88. Huang SS, Skolasky RL, Dal Pan GJ, et al. Survival prolongation in HIV-associated progressive multifocal leukoencephalopathy treated with alpha-interferon: an observational study. J Neurovirol 1998;4:324-332
89. Kerr DA, Chang CF, Gordon J, Bjornsti MA, Khalili K. Inhibition of human neurotropic virus (JCV) DNA replication in glial cells by camptothecin. Virology 1993;196:612-618.