The role of chemokines in allergic contact dermatitis

Archives of Dermatological Research

Volumn 293, Issue 11, 2002, Pages 552-559

  Sebastiani, Silvia ^a   Albanesi, Cristina ^a   De Pità, Ornella ^a   Puddu, Pietro ^a   Cavani, Andrea ^a   Girolomoni, Giampiero ^a  

^a LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

Author keywords

Cell mediated immunity; Chemokines; Leukocyte traffic; Skin

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CCR8; GAMMA INTERFERON; HAPTEN; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL FUNCTION; CELL MATURATION; CELL MIGRATION; CELL SECRETION; CELL SURFACE; CONTROLLED STUDY; DENDRITIC CELL; DISEASE ASSOCIATION; DISEASE MODEL; ENDOTHELIUM CELL; FIBROBLAST; HUMAN; HUMAN TISSUE; KERATINOCYTE; LEUKOCYTE; LYMPH NODE; MAST CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN TARGETING; REGULATORY MECHANISM; SENSITIZATION; SKIN; SKIN ALLERGY; SKIN CELL; SKIN INFLAMMATION; T LYMPHOCYTE; TREATMENT PLANNING;

EID: 0035714198     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-001-0276-9     Document Type: Article

References (65)

1. The role of chemokine receptors in primary, effector, and memory immune responses
2. Chemokines: Immunology's high impact factors
3. Chemokines: A new classification system and their role in immunity
4. A new class of membrane-bound chemokine with a CX3C motif
5. Chemokines as regulators of T cell differentiation
6. Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells
7. The biology of chemokines and their receptors
8. Human G protein-coupled receptor GPR9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis
9. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells
10. CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells
11. The orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin associated chemokine CCL27 (CTACK/ALP/ILC)
12. Lymphocyte traffic control by chemokines
13. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes
14. Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo
15. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1 s) and Th2 s
16. Selective up-regulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2 Th cells
17. + T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responses
18. + T lymphocytes with regulatory activity
19. Two subsets of memory T lymphocytes with distinct homing potential and effector function
20. Inflammatory skin diseases, T cells, and immune surveillance
21. CC-chemokine receptor 6 is expressed in diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3α
22. C-C chemokine receptor 6 is essential for arrest of a subset of memory T cells on activated dermal microvascular endothelial cells under physiologic flow conditions in vitro
23. Interleukin-8 immunoreactivity in the skin of healthy subjects and patients with palmoplantar pustulosis and psoriasis
24. Macrophage inflammatory protein 3α is involved in the constitutive trafficking of epidermal Langerhans cells
25. Up-regulation of macrophage inflammatory protein 3α/CCL20 and CC chemokine receptor 6 in psoriasis
26. Macrophage inflammatory protein 3α is expressed at inflamed epithelial cell surfaces and is the most potent chemokine known in attracting Langerhans cell precursors
27. Inducible expression of a CC chemokine liver- and activation-regulated chemokine (LARC)/macrophage inflammatory protein (MIP)-3α/CCL20 by epidermal keratinocytes and its role in atopic dermatitis
28. + lymphocytes into lesional atopic dermatitis skin
29. A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases
30. Interleukin-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: Synergistic or antagonist effects with interferon-γ and tumor necrosis factor-α
31. Interleukin 17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-γ- and interleukin 4-induced activation of human keratinocytes
32. IL-4 enhances keratinocyte expression of CXCR3 agonistic chemokines
33. Dysregulated activation of activator protein 1 in keratinocytes of atopic dermatitis patients with enhanced expression of granulocyte/macrophage-colony stimulating factor
34. Keratinocytes from patients with atopic dermatitis and psoriasis show a different chemokine production profile in response to T cell-derived cytokines
35. The role of chemokines in cutaneous allergic inflammation
36. IL-4 induces eotaxin: A possible mechanism of selective eosinophils recruitment in helminth infection and atopy
37. Detection of mRNA for eotaxin-2 and eotaxin-3 in human dermal fibroblasts and their distinct activation profile on human eosinophils
38. Detection of MCP-4 in dermal fibroblast and its activation of the respiratory burst in human eosinophils
39. Mast cell-T cell interactions
40. Distinct patterns and kinetics of chemokine production regulate dendritic cell function
41. Quantitative analysis of chemokine expression by dendritic cell subsets in vitro and in vivo
42. T-cell function and migration. Two sides of the same coin
43. Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses
44. Differential regulation of chemokine receptors during dendritic cell maturation: A model for their trafficking properties
45. Essential role of lymph nodes in contact hypersensitivity revealed in lymphotoxin-α-deficient mice
46. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
47. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization
48. + T lymphocytes primed by immunostimulating Langerhans cells
49. + T cell-mediated contact hypersensitivity
50. + type 1 cytotoxic T cells both play a crucial role in the full development of contact hypersensitivity
51. + T cell subsets against keratinocytes
52. T cell-mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis
53. Effector and regulatory T cells in allergic contact dermatitis
54. Reversal of established delayed type hypersensitivity reactions following therapy with IL-4 or antigen-specific Th2 cells
55. Signal transducer and activator of transcription 6 is essential in the induction of contact hypersensitivity
56. Differential and sequential expression of multiple chemokines during elicitation of allergic contact hypersensitivity
57. Keratinocyte-derived monocyte chemoattractant protein 1 (MCP-1): Analysis in a transgenic model demonstrates MCP-1 can recruit dendritic and Langerhans cells to skin
58. Modulation of leukocyte adhesion molecule, a T-cell chemotaxin (IL-8) and a regulatory cytokine (TNFα) in allergic contact dermatitis (rhus dermatitis)
59. Early local generation of C5a initiates the elicitation of contact sensitivity by leading to early T cell recruitment
60. Mast cells control neutrophil recruitment during T cell-mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2
61. The CXCR3 activating chemokines IP-10, Mig, and IP-9 are expressed in allergic but not in irritant patch test reactions
62. + T cells during the elicitation phase of contact hypersensitivity
63. Evidence for functional relevance of CTLA-4 in ultraviolet-radiation-induced tolerance
64. CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses
65. Chemokines IL-8, Gro-α, MCP-1, IP-10, and MIG are sequentially and differentially expressed during phase-specific infiltration of leukocyte subset in human wound healing