메뉴 건너뛰기




Volumn 38, Issue 2, 1999, Pages 267-271

Pregnenolone sulfate and dehydroepiandrosterone sulfate inhibit GABA-gated chloride currents in Xenopus oocytes expressing picrotoxin-insensitive GABA(A) receptors

Author keywords

GABA; Neurosteroids; Picrotoxin; Pregnenolone sulfate

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; NEUROSTEROID; PICROTOXIN; PICROTOXININ; PRASTERONE SULFATE; PREGNENOLONE SULFATE; RECEPTOR SUBUNIT;

EID: 0033008802     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(98)00172-5     Document Type: Article
Times cited : (54)

References (18)
  • 2
    • 0024513369 scopus 로고
    • Complex interactions between pregnenolone sulfate and the t-butyl-bicyclophosphorothionate-labeled chloride ionophore in rat brain
    • Gee, K.W., Joy, D.S., Belelli, D., 1989. Complex interactions between pregnenolone sulfate and the t-butyl-bicyclophosphorothionate-labeled chloride ionophore in rat brain. Brain Res. 482, 169-173.
    • (1989) Brain Res. , vol.482 , pp. 169-173
    • Gee, K.W.1    Joy, D.S.2    Belelli, D.3
  • 7
    • 0025091447 scopus 로고
    • The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor
    • Majewska, M.D., Demirgoren, S., Spivak, C.E., London, E.D., 1990. The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor. Brain Res. 526, 143-146.
    • (1990) Brain Res. , vol.526 , pp. 143-146
    • Majewska, M.D.1    Demirgoren, S.2    Spivak, C.E.3    London, E.D.4
  • 8
    • 0023940075 scopus 로고
    • Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons
    • Majewska, M.D., Mienville, J.-M., Vicini, S., 1988. Neurosteroid pregnenolone sulfate antagonizes electrophysiological responses to GABA in neurons. Neurosci. Lett. 90, 279-284.
    • (1988) Neurosci. Lett. , vol.90 , pp. 279-284
    • Majewska, M.D.1    Mienville, J.-M.2    Vicini, S.3
  • 9
    • 0023114555 scopus 로고
    • Pregnenolone sulfate: An endogenous antagonist of the γ-aminobutyric acid receptor complex in brain
    • Majewska, M.D., Schwartz, R.D., 1987. Pregnenolone sulfate: an endogenous antagonist of the γ-aminobutyric acid receptor complex in brain. Brain Res. 404, 355-360.
    • (1987) Brain Res. , vol.404 , pp. 355-360
    • Majewska, M.D.1    Schwartz, R.D.2
  • 10
    • 0024343524 scopus 로고
    • A receptor-mediated currents via a reduction of channel opening frequency
    • A receptor-mediated currents via a reduction of channel opening frequency. Brain Res. 489, 190-194.
    • (1989) Brain Res. , vol.489 , pp. 190-194
    • Mienville, J.-M.1    Vicini, S.2
  • 11
    • 0032474840 scopus 로고    scopus 로고
    • A receptor pharmacology of enantiomers of dehydroepiandrosterone sulfate, pregnenolone sulfate and (3α,5β)-3-hydroxypregnan-20-one sulfate
    • A receptor pharmacology of enantiomers of dehydroepiandrosterone sulfate, pregnenolone sulfate and (3α,5β)-3-hydroxypregnan-20-one sulfate. J. Med. Chem. 41, 2604-2613.
    • (1998) J. Med. Chem. , vol.41 , pp. 2604-2613
    • Nilsson, K.R.1    Zorumski, C.F.2    Covey, D.E.3
  • 12
    • 0016806065 scopus 로고
    • Structure-activity relationships in steroidal anaesthetics
    • Phillips, G.H., 1975. Structure-activity relationships in steroidal anaesthetics. J. Steroid Biochem. 6, 607-613.
    • (1975) J. Steroid Biochem. , vol.6 , pp. 607-613
    • Phillips, G.H.1
  • 13
    • 0030854871 scopus 로고    scopus 로고
    • A receptor complex reveals that it may act via the picrotoxin site
    • A receptor complex reveals that it may act via the picrotoxin site. J. Pharmacol. Exp. Ther. 282, 827-833.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 827-833
    • Sousa, A.1    Ticku, M.K.2
  • 14
    • 0028204425 scopus 로고
    • A receptors in ventral midbrain neurons by a neurosteroid dehydroepiandrosterone sulfate
    • A receptors in ventral midbrain neurons by a neurosteroid dehydroepiandrosterone sulfate. Synapse 16, 113-122.
    • (1994) Synapse , vol.16 , pp. 113-122
    • Spivak, C.E.1
  • 18
    • 0031921429 scopus 로고    scopus 로고
    • Enantioselective modulation of GABAergic synaptic transmission by steroids and benz[e]indenes in hippocampal microcultures
    • Zorumski, C.F., Mennerick, S.J., Covey, D.F., 1998. Enantioselective modulation of GABAergic synaptic transmission by steroids and benz[e]indenes in hippocampal microcultures. Synapse 29, 162-171.
    • (1998) Synapse , vol.29 , pp. 162-171
    • Zorumski, C.F.1    Mennerick, S.J.2    Covey, D.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.