In vivo expression of therapeutic human genes for dopamine production in the caudales of MPTP-treated monkeys using an AAV vector

Gene Therapy

Volumn 5, Issue 6, 1998, Pages 820-827

  During, M J ^a   Samulski, R J ^b   Elsworth, J D ^c   Kaplitt, M G ^d   Leone, P ^e   Xiao, X ^f   Li, J ^g   Freese, A ^h   Taylor, J R ⁱ   Roth, R H ^j   Sladek Jr, J R ^a   O'Malley, K L ^b   De Jr, Redmond ^c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c Departments of Psychiatry and Human Behavior   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e The Neiv York HospitalCornell University Medical College   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^h WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ YALE UNIVERSITY   (United States)

^j THOMAS JEFFERSON UNIVERSITY   (United States)

more..

Author keywords

AAV; Brain; Dopamine; Monkey; Parkinson; Tyrosine hydroxylase

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; AROMATIC LEVO AMINO ACID DECARBOXYLASE; BETA GALACTOSIDASE; DOPAMINE; NEUROTOXIN; TYROSINE 3 MONOOXYGENASE; VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CAUDATE NUCLEUS; DOPAMINE METABOLISM; EMBRYO; GENE THERAPY; HUMAN; HUMAN CELL; KIDNEY CELL; MONKEY; NONHUMAN; PARKINSONISM; PRIORITY JOURNAL; STEREOTAXIC SURGERY; TOXICITY;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; AROMATIC-L-AMINO-ACID DECARBOXYLASES; CERCOPITHECUS AETHIOPS; DEPENDOVIRUS; DOPAMINE; DOPAMINE AGENTS; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; PARKINSON DISEASE; TRIGEMINAL CAUDAL NUCLEUS; TYROSINE 3-MONOOXYGENASE;

ADENO-ASSOCIATED VIRUS; ANIMALIA; DNA VIRUSES; PARKINSONIA; PRIMATES;

EID: 0031875751     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300650     Document Type: Article

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