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Volumn 15, Issue SUPPL. 5, 2001, Pages

The HIV vaccine pipeline, from preclinical to phase III

(2)  Schultz, A M a   Bradac, J A a  

a NONE   (United States)

Author keywords

AIDS vaccine; HIV; HIV protein immunogens; Nucleic acid immunization; Vaccine vectors

Indexed keywords

ALVAC B; ALVAC E; EPIMMUNE; EUROVAC; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NUCLEIC ACID; NYVAC; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS VECTOR;

EID: 0035659831     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200100005-00018     Document Type: Review
Times cited : (30)

References (86)
  • 1
  • 5
    • 0026647845 scopus 로고
    • Neutralization of multiple laboratory and clinical isolates of human immunodeficiency virus type 1 (HIV-1) by antisera raised against gp120 from the MN isolate of HIV-1
    • (1992) J Virol , vol.66 , pp. 4464-4469
    • Berman, P.W.1    Matthews, T.J.2    Riddle, L.3
  • 6
    • 0005000433 scopus 로고
    • HIV-1 neutralization: The consequences of viral adaptation to growth on transformed T cells
    • (1995) AIDS , vol.9 , Issue.SUPPL. A
    • Moore, J.P.1    Ho, D.D.2
  • 7
    • 19144365910 scopus 로고    scopus 로고
    • Immunization with envelope subunit vaccine products elicits neutralizing antibodies against laboratory-adapted but not primary isolates of human immunodeficiency virus type 1
    • (1996) J Infect Dis , vol.173 , pp. 340-348
    • Mascola, J.R.1    Snyder, S.W.2    Weislow, O.S.3
  • 9
    • 0034663142 scopus 로고    scopus 로고
    • Evaluation of immune responses induced by HIV-1 gp120 in rhesus macaques: Effect of vaccination on challenge with pathogenic strains of homologous and heterologous simian human immunodeficiency viruses
    • (2000) Virology , vol.274 , pp. 149-164
    • Kumar, A.1    Lifson, J.D.2    Silverstein, P.S.3
  • 11
    • 0032949148 scopus 로고    scopus 로고
    • Comparison of the antibody repertoire generated in healthy volunteers following immunization with a monomeric recombinant gp120 construct derived from a CCR5/CXCR4-using human immunodeficiency virus type 1 isolate with sera from naturally infected individuals
    • J Virol , vol.73 , pp. 1740-1745
    • Beddows, S.1    Lister, S.2    Cheingsong, R.3
  • 12
    • 0034967872 scopus 로고    scopus 로고
    • Induction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques
    • (2001) J Virol , vol.75 , pp. 5879-5890
    • Montefiori, D.C.1    Safrit, J.T.2    Lydy, S.L.3
  • 14
    • 0035124098 scopus 로고    scopus 로고
    • Polyvalent envelope glycoprotein vaccine elicits a broader neutralizing antibody response but is unable to provide sterilizing protection against heterologous simian/human immunodeficiency virus infection in pigtailed macaques
    • (2001) J Virol , vol.75 , pp. 2224-2234
    • Cho, M.W.1    Kim, Y.B.2    Lee, M.K.3
  • 16
    • 0028355456 scopus 로고
    • Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities
    • (1994) J Virol , vol.68 , pp. 3015-3026
    • Earl, P.L.1    Broder, C.C.2    Long, D.3
  • 18
    • 0033985999 scopus 로고    scopus 로고
    • A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure
    • (2000) J Virol , vol.74 , pp. 627-643
    • Binley, J.M.1    Sanders, R.W.2    Clas, B.3
  • 19
    • 0034004321 scopus 로고    scopus 로고
    • Modifications that stabilize human immunodeficiency virus envelope glycoprotein trimers in solution
    • (2000) J Virol , vol.74 , pp. 4746-4754
    • Yang, X.1    Florin, L.2    Farzan, M.3
  • 20
    • 0035155850 scopus 로고    scopus 로고
    • Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers
    • (2001) J Virol , vol.75 , pp. 1165-1171
    • Yang, X.1    Wyatt, R.2    Sodroski, J.3
  • 21
    • 0031694872 scopus 로고    scopus 로고
    • Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins
    • (1998) J Virol , vol.72 , pp. 7992-8001
    • Rossio, J.L.1    Esser, M.T.2    Suryanarayana, K.3
  • 22
    • 0030895045 scopus 로고    scopus 로고
    • Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light
    • (1997) Transfusion , vol.37 , pp. 423-435
    • Lin, L.1    Cook, D.N.2    Wiesehahn, G.P.3
  • 23
    • 0031748799 scopus 로고    scopus 로고
    • Identification of replication-competent strains of simian immunodeficiency virus lacking multiple attachment sites for N-linked carbohydrates in variable regions 1 and 2 of the surface envelope protein
    • (1998) J Virol , vol.72 , pp. 5399-5407
    • Reitter, J.N.1    Desrosiers, R.C.2
  • 24
    • 0031666180 scopus 로고    scopus 로고
    • An envelope modification that renders a primary, neutralization-resistant clade B human immunodeficiency virus type 1 isolate highly susceptible to neutralization by sera from other clades
    • (1998) J Virol , vol.72 , pp. 7840-7845
    • Stamatatos, L.1    Cheng-Mayer, C.2
  • 25
    • 0035148591 scopus 로고    scopus 로고
    • DNA vaccination with the human immunodeficiency virus type 1 SF162deltaV2 envelope elicits immune responses that offer partial protection from simian/human immunodeficiency virus infection to CD8(+) T-cell-depleted rhesus macaques
    • (2001) J Virol , vol.75 , pp. 1547-1550
    • Cherpelis, S.1    Shrivastava, I.2    Gettie, A.3
  • 26
    • 0035000679 scopus 로고    scopus 로고
    • The ability of an oligomeric human immunodeficiency virus type 1 (HIV-1) envelope antigen to elicit neutralizing antibodies against primary HIV-1 isolates is improved following partial deletion of the second hypervariable region
    • (2001) J Virol , vol.75 , pp. 5526-5540
    • Barnett, S.W.1    Lu, S.2    Srivastava, I.3
  • 27
    • 0027256814 scopus 로고
    • Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding
    • (1993) J Virol , vol.67 , pp. 3978-3988
    • Thali, M.1    Moore, J.P.2    Furman, C.3
  • 29
    • 0029927680 scopus 로고    scopus 로고
    • Covalently crosslinked complexes of human immuno-deficiency virus type 1 (HIV-1) gp120 and CD4 receptor elicit a neutralizing immune response that includes antibodies selective for primary virus isolates
    • (1996) Virology , vol.218 , pp. 258-263
    • Devico, A.1    Silver, A.2    Thronton, A.M.3
  • 30
    • 0034467954 scopus 로고    scopus 로고
    • Expression and characterization of a single-chain polypeptide analogue of the human immunodeficiency virus type 1 gp120-CD4 receptor complex
    • (2000) J Virol , vol.74 , pp. 11427-11436
    • Fouts, T.R.1    Tuskan, R.2    Godfrey, K.3
  • 31
    • 0031985314 scopus 로고    scopus 로고
    • Spontaneous mutations in the env gene of the human immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype
    • (1998) J Virol , vol.72 , pp. 512-519
    • Dumonceaux, J.1    Nisole, S.2    Chanel, C.3
  • 41
    • 0032866049 scopus 로고    scopus 로고
    • Role of immune responses against the envelope and the core antigens of simian immunodeficiency virus SIVmne in protection against homologous cloned and uncloned virus challenge in macaques
    • (1999) J Virol , vol.73 , pp. 8201-8215
    • Polacino, P.S.1    Stallard, V.2    Klaniecki, J.E.3
  • 44
    • 0018246525 scopus 로고
    • The smallpox vaccination strain MVA: Marker, genetic structure, experience gained with the parenteral vaccination and behaviour in organisms with a debilitated defence mechanism
    • (1978) Zentbl Bacteriol Hyg B , vol.167 , pp. 375-390
    • Mayr, A.1    Stickl, H.2    Muller, H.K.3
  • 45
    • 0033995525 scopus 로고    scopus 로고
    • Recombinant modified vaccinia virus Ankara expressing the surface gp120 of simian immunodeficiency virus (SIV) primes for a rapid neutralizing antibody response to SIV infection in macaques
    • (2000) J Virol , vol.74 , pp. 2960-2965
    • Ourmanov, I.1    Bilska, M.2    Hirsch, V.M.3    Montefiori, D.C.4
  • 46
    • 0034093217 scopus 로고    scopus 로고
    • Comparative efficacy of recombinant modified vaccinia virus Ankara expressing simian immunodeficiency virus (SIV) Gag-Pol and/or Env in macaques challenged with pathogenic SIV
    • (2000) J Virol , vol.74 , pp. 2740-2751
    • Ourmanov, I.1    Brown, C.R.2    Moss, B.3
  • 47
    • 0034088113 scopus 로고    scopus 로고
    • Immunization with a modified vaccinia virus expressing simian immunodeficiency virus (SIV) Gag-Pol primes for an anamnestic Gag-specific cytotoxic T-lymphocyte response and is associated with reduction of viremia after SIV challenge
    • (2000) J Virol , vol.74 , pp. 2502-2509
    • Seth, A.1    Ourmanov, I.2    Schmitz, J.E.3
  • 49
    • 18344405225 scopus 로고    scopus 로고
    • Recombinant vaccine-induced protection against the highly pathogenic simian immunodeficiency virus SIV(mac251): Dependence on route of challenge exposure
    • (1998) J Virol , vol.72 , pp. 4170-4182
    • Benson, J.1    Chougnet, C.2    Robert-Guroff, M.3
  • 51
    • 0033988633 scopus 로고    scopus 로고
    • Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles
    • (2000) J Virol , vol.74 , pp. 371-378
    • Davis, N.L.1    Caley, I.J.2    Brown, K.W.3
  • 52
    • 0034467969 scopus 로고    scopus 로고
    • Infection of human dendritic cells by a Sindbis virus replicon vector is determined by a single amino acid substitution in the E2 glycoprotein
    • (2000) J Virol , vol.74 , pp. 11849-11857
    • Gardner, J.P.1    Frolov, I.2    Perri, S.3
  • 59
    • 0034090316 scopus 로고    scopus 로고
    • Expression of human immunodeficiency virus type 1 Gag protein precursor and envelope proteins from a vesicular stomatitis virus recombinant: High-level production of virus-like particles containing HIV envelope
    • (2000) Virology , vol.268 , pp. 112-121
    • Haglund, K.1    Forman, J.2    Krausslich, H.G.3    Rose, J.K.4
  • 60
    • 0034467097 scopus 로고    scopus 로고
    • Glycoprotein exchange vectors based on vesicular stomatitis virus allow effective boosting and generation of neutralizing antibodies to a primary isolate of human immunodeficiency virus type 1
    • (2000) J Virol , vol.74 , pp. 10903-10910
    • Rose, N.F.1    Roberts, A.2    Buonocore, L.3    Rose, J.K.4
  • 61
    • 0035043384 scopus 로고    scopus 로고
    • Rabies virus-based vectors expressing human immunodeficiency virus type 1 (HIV-1) envelope protein induce a strong, cross-reactive cytotoxic T-lymphocyte response against envelope proteins from different HIV-1 isolates
    • (2001) J Virol , vol.75 , pp. 4430-4434
    • McGettigan, J.P.1    Foley, H.D.2    Belyakov, I.M.3
  • 63
    • 0033803502 scopus 로고    scopus 로고
    • Recombinant yellow fever viruses are effective therapeutic vaccines for treatment of murine experimental solid tumors and pulmonary metastases
    • (2000) J Virol , vol.74 , pp. 9197-9205
    • McAllister, A.1    Arbetman, A.E.2    Mandl, S.3
  • 66
    • 0031725117 scopus 로고    scopus 로고
    • Chimeric influenza virus replicating predominantly in the murine upper respiratory tract induces local immune responses against human immunodeficiency virus type 1 in the genital tract
    • (1998) J Infect Dis , vol.178 , pp. 1359-1368
    • Ferko, B.1    Katinger, D.2    Grassauer, A.3
  • 71
    • 0035120341 scopus 로고    scopus 로고
    • Systemic immunity and mucosal immunity are induced against human immunodeficiency virus gag protein in mice by a new hyperattenuated strain of Listeria monocytogenes
    • (2001) J Virol , vol.75 , pp. 2786-2791
    • Rayevskaya, M.V.1    Frankel, F.R.2
  • 72
    • 0033563267 scopus 로고    scopus 로고
    • Selection of HIV-specific immunogenic epitopes by screening random peptide libraries with HIV-1-positive sera
    • (1999) J Immunol , vol.162 , pp. 6155-6161
    • Scala, G.1    Chen, X.2    Liu, W.3
  • 76
    • 0034703836 scopus 로고    scopus 로고
    • Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine
    • (2000) Vaccine , vol.19 , pp. 764-778
    • Roy, M.J.1    Wu, M.S.2    Barr, L.J.3
  • 78
    • 0033868431 scopus 로고    scopus 로고
    • Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection
    • (2000) J Virol , vol.74 , pp. 7485-7495
    • Egan, M.A.1    Charini, W.A.2    Kuroda, M.J.3
  • 81
    • 0033019064 scopus 로고    scopus 로고
    • HIV-1 vaccine-induced immune responses which correlate with protection from SHIV infection: Compiled preclinical efficacy data from trials with ten different HIV-1 vaccine candidates
    • (1999) Immunol Lett , vol.66 , pp. 189-195
    • Heeney, J.1    Akerblom, L.2    Barnett, S.3
  • 83
    • 0033826855 scopus 로고    scopus 로고
    • Design and construction of an experimental HIV-1 vaccine for a year-2000 clinical trial in Kenya
    • (2000) Nat Med , vol.6 , pp. 951-955
    • Hanke, T.1    McMichael, A.J.2
  • 84
    • 0034667917 scopus 로고    scopus 로고
    • HIV gag mRNA transfection of dendritic cells (DC) delivers encoded antigen to MHC class I and II molecules, causes DC maturation, and induces a potent human in vitro primary immune response
    • (2000) J Immunol , vol.165 , pp. 4710-4717
    • Weissman, D.1    Ni, H.2    Scales, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.