Genetically modified anthrax lethal toxin safely delivers whole HIV protein antigens into the cytosol to induce T cell immunity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 14, 2000, Pages 8027-8032

  Lu, Yichen ^a   Friedman, Rachel ^b   Kushner, Nicholas ^a   Doling, Amy ^b   Thomas, Lawrence ^c   Touzjian, Neal ^a   Starnbach, Michael ^b   Lieberman, Judy ^b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c AVANT Immunotherapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXIN; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

ARTICLE; BACILLUS ANTHRACIS; CELLULAR IMMUNITY; CYTOTOXIC T LYMPHOCYTE; HELPER CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VACCINATION;

AIDS VACCINES; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; BACTERIAL TOXINS; CD8-POSITIVE T-LYMPHOCYTES; CYTOSOL; CYTOTOXICITY TESTS, IMMUNOLOGIC; CYTOTOXICITY, IMMUNOLOGIC; DRUG CARRIERS; HIV ANTIGENS; MACROPHAGES; MICE; MICE, INBRED BALB C; PROTEIN ENGINEERING; RABBITS; RECOMBINANT FUSION PROTEINS; VACCINATION;

ANIMALIA; ANTHRAX; BACILLUS ANTHRACIS; BACILLUS ANTHRAX; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0034608874     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.14.8027     Document Type: Article

References (27)