Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light

Transfusion

Volumn 37, Issue 4, 1997, Pages 423-435

  Lin, L ^a   Cook, D N ^a   Wiesehahn, G P ^a   Alfonso, R ^a   Behrman, B ^a   Cimino, G D ^a   Corten, L ^a   Damonte, P B ^a   Dikeman, R ^a   Dupuis, K ^a   Fang, Y M ^a   Hanson, C V ^a   Hearst, J E ^a   Lin, C Y ^a   Londe, H F ^a   Metchette, K ^a   Nerio, A T ^a   Pu, J T ^a   Reames, A A ^a   Rheinschmidt, M ^a   Tessman, J ^a   Isaacs, S T ^a   Wollowitz, S ^a   Corash, L ^a   more..

^a CERUS CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PSORALEN;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; BLOOD TRANSFUSION REACTION; HEPATITIS B VIRUS; INFECTIOUS COMPLICATION; KLEBSIELLA PNEUMONIAE; NONHUMAN; PHOTOCHEMISTRY; RAT; STAPHYLOCOCCUS EPIDERMIDIS; THROMBOCYTE FUNCTION; THROMBOCYTE TRANSFUSION; ULTRAVIOLET A RADIATION; ULTRAVIOLET IRRADIATION; VIRUS INFECTION;

EID: 0030895045     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1537-2995.1997.37497265344.x     Document Type: Article

References (40)

1. Dodd RY. Adverse consequences of blood transfusion: quantitative risk estimates. In: Nance ST, ed. Blood supply: risks, perceptions and prospects for the future. Bethesda: American Association of Blood Banks, 1994:1-24.
2. Lackritz EM, Satten GA, Aberle-Grasse J, et al. Estimated risk of transmission of the human immunodeficiency virus by screened blood in the United States. N Engl J Med 1995;333:1721-5.
3. Goldman M, Blajchman MA. Blood product-associated bacterial sepsis. Transfus Med Rev 1991;5:73-83.
4. Morrow JF, Braine HG, Kickler TS, et al. Septic reactions to platelet transfusions. A persistent problem. JAMA 1991;266:555-8.
5. Blajchman MA, Ali AM. Bacteria in the blood supply: an overlooked issue in transfusion medicine. In: Nance ST, ed. Blood safety: current challenges. Bethesda: American Association of Blood Banks, 1992:213-28.
6. Chiu EKW, Yuen KY, Lie AKW, et al. A prospective study of symptomatic bacteremia following platelet transfusion and of its management. Transfusion 1994;34:950-4.
7. Wallace EL, Churchill WH, Surgenor DM, et al. Collection and transfusion of blood and blood components in the United States, 1992. Transfusion 1995;35:802-12.
8. Cimino GD, Gamper HB, Isaacs ST, Hearst JE. Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry. Annu Rev Biochem 1985;54:1151-93.
9. Lin L, Wiesehahn GP, Morel PA, Corash L. Use of 8-methoxypsoralen and long-wavelength ultraviolet radiation for decontamination of platelet concentrates. Blood 1989;74:517-25.
10. Wollowitz S, Isaacs ST, Rapoport H, Spielmann HP, inventors; Cerus Corporation, assignee. Compounds for the photodecontamination of pathogens in blood. US patent 5,399,719. 1995 March 21.
11. Gulliksson H, Eriksson L, Högman CF, Payrat IM. Buffy-coat-derived platelet concentrates prepared from half-strength cit-rate CPD and CPD whole-blood units. Comparison between three additive solutions: in vitro studies. Vox Sang 1995;68:152-9.
12. Popovic M, Sarin PS, Robert-Gurroff M, et al. Isolation and transmission of human retrovirus (human t-cell leukemia virus). Science 1983;219:856-9.
13. Hanson CV, Crawford-Miksza L, Sheppard HW. Application of a rapid microplaque assay for determination of human immunodeficiency virus neutralizing antibody titers. J Clin Microbiol 1990;28:2030-4.
14. Butera ST, Perez VL, Wu BY, et al. Oscillation of the human immunodeficiency virus surface receptor is regulated by the state of viral activation in a CD4+ cell model of chronic infection. J Virol 1991;65:4645-53.
15. Sambrook J, Fritsch EF, Maniatis T, eds. Molecular cloning: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
16. Reed LJ, Muench H. A simple method of estimating fifty percent endpoints. Am J Hygiene 1938;27:493-7.
17. Kunicki TJ, Tuccelli M, Becker GA, Aster RH. A study of variables affecting the quality of platelets stored at "room temperature." Transfusion 1975;15:414-21.
18. DiMinno G, Silver MJ, Murphy S. Stored human platelets retain full aggregation potential in response to pairs of aggregating agents. Blood 1982;59:563-8.
19. Ingerman-Wojenski CM, Silver MJ. A quick method for screening platelet dysfunctions using the whole blood lumi-aggregometer. Thromb Haemost 1984;52:154-6.
20. Handin RI, Fortier NL, Valeri CR. Platelet response to hypotonic stress after storage at 4C or 22C. Transfusion 1970;10:305-9.
21. Holme S, Vaidja K, Murphy S. Platelet storage at 22°C: effect of type of agitation on morphology, viability, and function in vitro. Blood 1978;52:425-35.
22. McEver RP, Martin MN. A monoclonal antibody to a membrane glycoprotein binds only to activated platelets. J Biol Chem 1984;259:9799-804.
23. Stenberg PE, McEver RP, Shuman MA, et al. A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J Cell Biol 1985;101:880-6.
24. Lin L, Londe H, Janda JM, et al. Photochemical inactivation of pathogenic bacteria in human platelet concentrates. Blood 1994;83:2698-706.
25. Murphy EA, Francis ME. The estimation of blood platelet survival. II. The multiple hit model. Thromb Diath Haemorrh 1971;25:53-80.
26. Ganem D, Varmus HE. The molecular biology of the hepatitis B viruses. Annu Rev Biochem 1987;56:651-93.
27. Choo QL, Kuo G, Weiner AJ, et al. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989;244:359-62.
28. Lee TH, Stromberg RR, Henrard D, Busch MP. Effect of platelet-associated virus on assays of HIV-1 in plasma. Science 1993;262:1585-6.
29. Wagner SJ, Robinette D, Storry J, et al. Differential sensitivities of viruses in red cell suspensions to methylene blue photosensitization. Transfusion 1994;34:521-6.
30. Ben-Hur E, Horowitz B. Advances in photochemical approaches for blood sterilization. Photochem Photobiol 1995;62:383-8.
31. Goodrich RP, Yerram NR, Tay-Goodrich BH, et al. Selective inactivation of viruses in the presence of human platelets: UV sensitization with psoralen derivatives. Proc Natl Acad Sci U S A 1994;91:5552-6.
32. Lin L, Cook D, Londe H, et al. Use of variable length amplicons to determine the efficiency of viral inactivation by psoralen mediated photochemistry (abstract). Blood 1993;82(Suppl 1):401a.
33. Anderson KC, Lew MA, Gorgone BC, et al. Transfusion-related sepsis after prolonged platelet storage. Am J Med 1986;81:405-11.
34. Londe H, Alfonso R, Janda M, et al. Photochemical inactivation of bacteria in platelet concentrates (abstract). Vox Sang 1994;67(Suppl 2):21.
35. Lin L, Dikeman R, Corten L, et al. Photochemical inactivation of pathogenic bacteria in platelet concentrates using a novel psoralen (abstract). Transfusion 1994;34(Suppl):43S.
36. Nikaido H, Vaara M. Molecular basis of bacterial outer membrane permeability. Microbiol Rev 1985;49:1-32.
37. Murphy S, Rebulla P, Bertolini F, et al. In vitro assessment of the quality of stored platelet concentrates. The BEST (Biomedical Excellence for Safer Transfusion) Task Force of the International Society of Blood Transfusion. Transfus Med Rev 1994;8:29-36.
38. Rinder HM, Murphy M, Mitchell JG, et al. Progressive platelet activation with storage: evidence for shortened survival of activated platelets after transfusion. Transfusion 1991;31:409-14.
39. Triulzi DJ, Houston A, Kiss JE, Winkelstein A. The p-selectin epitope recognized by anti-CD62 on activated platelets does not correlate with platelet recovery (abstract). Transfusion 1994;34(Suppl):77S.
40. Goodrich RP, Yerram NR, Crandall SL, Soroemimo-Coker SO. In vivo survival of platelets subjected to virus inactivation protocols using psoralen and coumarin photosensitizers (abstract). Blood 1995;86(Suppl 1):354a.