Identification of replication-competent strains of simian immunodeficiency virus lacking multiple attachment sites for N-linked carbohydrates in variable regions 1 and 2 of the surface envelope protein

Journal of Virology

Volumn 72, Issue 7, 1998, Pages 5399-5407

  Reitter, Julie N ^a   Desrosiers, Ronald C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; VIRUS DNA; VIRUS ENVELOPE PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; DNA SEQUENCE; HUMAN IMMUNODEFICIENCY VIRUS; HUMORAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; PROTEIN STRUCTURE; SIMIAN IMMUNODEFICIENCY VIRUS; SITE DIRECTED MUTAGENESIS; VIRUS MUTANT; VIRUS REPLICATION;

EID: 0031748799     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.7.5399-5407.1998     Document Type: Article

References (32)

1. Ahuja, S. K., and P. M. Murphy. 1996. Molecular piracy of mammalian interleukin-8 receptor type B by herpesvirus saimiri. J. Biol. Chem. 268: 20691-20694.
2. Alexander, L., Z. Du, M. Rosenzweig, J. U. Jung, and R. C. Desrosiers. 1997. A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation, J. Virol. 71:6094-6099.
3. Almond, N., A. Jenkins, A. B. Heath, and P. Kitchin. 1993. Sequence variation in the env gene of simian immunodeficiency virus recovered from immunized macaques is predominantly in the V1 region. J. Gen. Virol. 74: 865-871.
4. Back, N. K. T., L. Smit, J.-J. De Jong, W. Keulen, M. Schutten, J. Goudsmit, and M. Tersmette. 1994. An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization. Virology 199:431-438.
5. Bernstein, H. B., S. P. Tucker, E. Hunter, J. S. Schutzbach, and R. W. Compans. 1994. Human immunodeficiency virus type 1 envelope glycoprotein is modified by O-linked oligosaccharides. J. Virol. 68:463-468.
6. Bolmstedt, A., A. Hemming, P. Flodby, P. Berntsson, B. Travis, J. P. C. Lin, J. Ledbetter, T. Tsu, H. Wigzell, S.-L. Hu, and S. Olofsson. 1991. Effects of mutations in glycosylation sites and disulphide bonds on processing, CD4-binding and fusion activity of human immunodeficiency virus envelope glycoproteins. J. Gen. Virol. 72:1269-1277.
7. Burns, D. P. W., and R. C. Desrosiers. 1991. Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys. J. Virol. 65:1843-1854.
8. Chackerian, B., L. M. Rudensey, and J. Overbaugh. 1997. Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus that evolve in the host alter recognition by neutralizing antibodies. J. Virol. 71:7719-7727.
9. Du, Z., D. A. Regier, and R. C. Desrosiers. 1995. An improved recombinant PCR mutagenesis procedure that uses alkaline denatured plasmid template. BioTechniques 18:376-378.
10. Fennie, C., and L. A. Lasky. 1989. Model for intracellular folding of the human immunodeficiency virus type 1 gp120. J. Virol. 63:639-646.
11. Fenouillet, E., J. C. Gluckman, and E. Bahraoui. 1990. Role of N-linked glycans of envelope glycoproteins in infectivity of human immunodeficiency virus type 1. J. Virol. 64:2841-2848.
12. Fischer, P. B., G. B. Karlsson, T. D. Butters, R. A. Dwek, and F. M. Platt. 1996. N-Butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with changes in antibody recognition of the V1/V2 region of gp120. J. Virol. 70:7143-7152.
13. Fischer, P. B., G. B. Karlsson, R. A. Dwek, and F. M. Platt. 1996. N-Butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with impaired gp12U shedding and gp41 exposure. J. Virol. 70: 7153-7160.
14. Gruters, R. A., J. J. Neefjes, M. Tersmette, R. E. Y. de Goede, A. Tulp, H. G. Huisman, F. Miedema, and H. L. Ploegh. 1987. Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase. Nature 330:74-77.
15. Ilyinskii, P. O., and R. C. Desrosiers. 1996. Efficient transcription and replication of simian immunodeficiency virus in the absence of NF-κB and Sp1 binding elements. J. Virol. 70:3118-3126.
16. Kornfeld, R., and S. Kornfeld. 1985. Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem 54:631-664.
17. Lee, W.-R., W.-J. Syu, B. Du, M. Matsuda, S. Tan, A. Wolf, M. Essex, and T.-H. Lee. 1992. Nonrandom distribution of gp120 N-linked glycosylation sites important for infectivity of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 89:2213-2217.
18. Leonard, C. K., M. W. Spellman, L. Riddle, R. J. Harris, J. N. Thomas, and T. J. Gregory. 1990. Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells. J. Biol. Chem. 265:10373-10382.
19. Levesque, J.-P., P. Sanilvestri, A. Hatzfeld, and J. Hatzfeld. 1991. DNA transfection in Cos cells. BioTechniques 11:313-318.
20. Li, Y., L. Luo, N. Rasool, and C. Y. Kang. 1993. Glycosylation is necessary for the correct folding of human immunodeficiency virus gp120 in CD4 binding. J. Virol. 67:584-588.
21. Mori, K., D. J. Ringler, T. Kodama, and R. C. Desrosiers. 1992. Complex determinants of macrophage tropism in env of simian immunodeficiency virus. J. Virol. 66:2067-2075.
22. Morikawa, Y., J. P. Moore, A. J. Wilkinson, and I. M. Jones. 1991. Reduction in CD4 binding affinity associated with removal of a single glycosylation site in the external glycoprotein of HIV-2. Virology 180:853-856.
23. Morrison, H. G., F. Kirchhoff, and R. C. Desrosiers. 1993. Evidence for the cooperation of gp120 amino acids 322 and 448 in SIVmac entry. Virology 195:167-174.
24. Myers, G., B. Foley, J. W. Mellors, B. Korber, K.-T. Jeang, and S. Wain-Hobson. 1996. A compilation and analysis of nucleic acid and amino acid sequences. Los Alamos National Laboratory, Los Alamos, N.M.
25. Naidu, Y. M., H. W. Kestler, III, Y. Li, C. V. Butler, D. P. Silva, D. K. Schmidt, C. D. Troup, P. K. Sehgal, P. Sonigo, M. D. Daniel, and R. C. Desrosiers. 1988. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac. J. Virol. 62:4691-4696.
26. Ng, D. T. W., S. W. Hiebert, and R. A. Lamb. 1990. Different roles of individual N-linked oligosaccharide chains in folding, assembly, and transport of the simian virus 5 hemagglutinin-neuraminidase. Mol. Cell. Biol. 10: 1989-2001.
27. Pal, R., G. M. Hoke, and M. G. Sarngadharan. 1989. Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 86:3384-3388.
28. Pinter, A., and W. J. Honnen. 1988. O-linked glycosylation of retroviral envelope gene products. J. Virol. 62:1016-1021.
29. Regier, D. A., and R. C. Desrosiers. 1990. The complete nucleotide sequence of a pathogenic molecular clone of simian immunodeficiency virus. AIDS Res. Hum. Retroviruses 6:1221-1231.
30. Walker, B. D., M. Kowalski, W. C. Goh, K. Kozarsky, M. Krieger, C. Rosen, L. Rohrschneider, W. A. Haseltine, and J. Sodroski. 1987. Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine. Proc. Natl. Acad. Sci. USA 84:8120-8124.
31. Wang, W.-K., M. Essex, and T.-H. Lee. 1996. Single amino acid substitution in constant region 1 or 4 of gp120 causes the phenotype of a human immunodeficiency virus type 1 variant with mutations in hypervariable regions 1 and 2 to revert. J. Virol. 70:607-611.
32. Willey, R. L., D. H. Smith, L. A. Lasky, T. S. Theodore, P. L. Earl, B. Moss, D. J. Capon, and M. A. Martin. 1988. In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J. Virol. 62:139-147.