Importance of post-transcriptional regulation of chemokine genes by oxidative stress

Biochemical Journal

Volumn 360, Issue 2, 2001, Pages 321-333

  Josse, C ^a   Boelaert, J R ^a   Best Belpomme, M ^a   Piette, J ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Free radicals; Monocytes macrophages; MRNA; Transcription factors

Indexed keywords

ENZYMES; GENES; PROTEINS; RNA; VIRUSES;

NUCLEAR TRANSLOCATION;

BIOCHEMISTRY;

ALOXISTATIN; CHEMOKINE; CYTOKINE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LACTONE DERIVATIVE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; CYTOKINE PRODUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LYMPHOCYTE; MONOCYTE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS; TRANSCRIPTION REGULATION;

CELL-FREE SYSTEM; CHEMOKINE CCL2; CHEMOKINES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; INTERLEUKIN-8; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; U937 CELLS;

EID: 0035629777     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3600321     Document Type: Article

References (52)

1. Antioxidants, redox-regulated transcription factors, and inflammation
2. Cell and tissue responses to oxidative damage
3. Tissue destruction by neutrophils
4. Redox regulation of transcriptional activators
5. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1
6. Phosphorylation meets ubiquitination: The control of NF-κB activity
7. NF-κB and the innate immune response
8. The NF-κB/|κB system in acute inflammation
9. |κB kinase: Beginning, not the end
10. The crystal structure of the |κBα/NF-κB complex reveals mechanisms of NF-κB inactivation
11. The |κB kinase (IKK) and NF-κB: Key elements of proinflammatory signalling
12. A cytokine-responsive |κB kinase that activates the transcription factor NF-κB
13. |κB kinase-β: NF-κB activation and complex formation with |κB kinase-α and NIK
14. The IKK complex: An integrator of all signals that activate NF-κB?
15. Activation of the NF-κB transcription factor in a T-lymphocytic cell line by hypochlorous acid
16. Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of |κBα in NF-κB activation by an oxidative stress
17. Activators and target genes of Rel/NF-κB transcription factors
18. The biology of chemokines and their receptors
19. RelB, a new Rel family transcription activator that can interact with p50-NF-κB
20. Cytokine induction of monocyte chemoattractant protein-1 gene expression in human endothelial cells depends on the cooperative action of NF-κB and AP-1
21. C/EBP, NF-κB, and c-Ets family members and transcriptional regulation of the cell-specific and inducible macrophage inflammatory protein 1α immediate-early gene
22. 2 and tumor necrosis factor-α induce differential binding of the redox-responsive transcription factors AP-1 and NF-κB to the interleukin-8 promoter in endothelial and epithelial cells
23. 2 and tumor necrosis factor-α in endothelial and epithelial cells
24. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
25. Post-transcriptional regulation of gro-α, -β, -γ, and IL-8 mRNAs by IL-1 β
26. Molecular cloning and posttranscriptional regulation of macrophage inflammatory protein-1α in alveolar macrophages
27. Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade
28. Stress-activated protein kinases (JNK and p38/HOG) are essential for vascular endothelial growth factor mRNA stability
29. Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways
30. Combinations of ERK and p38 MAPK inhibitors ablate tumor necrosis factor-α (TNF-α) mRNA induction
31. Chemokines: A new classification system and their role in immunity
32. Chemokines
33. Chemokines in inflammation and immunity
34. Transcriptional and post-transcriptional regulation of interleukin-8
35. Stimulus-specific regulation of chemokine expression involves differential activation of the redox-responsive transcription factors AP-1 and NF-κB
36. Differential desensitization of lipopolysaccharide-inducible chemokine gene expression in human monocytes and macrophages
37. Regulation of macrophage inflammatory protein-1α mRNA by oxidative stress
38. Regulation of interleukin 8 gene expression by oxidant stress
39. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
40. Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators
41. Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation
42. Identification of a GA-rich sequence as a protein-binding site in the 3′-untranslated region of chicken elastin mRNA with a potential role in the developmental regulation of elastin mRNA stability
43. Developmental regulation of RNA transcript destabilisation by A + U-rich elements is AUF1-dependent
44. Protein kinase regulates tumor necrosis factor mRNA stability in virus-stimulated astrocytes
45. Interactions of CCCH zinc-finger proteins with mRNA. Binding of tristetraproline-related zinc finger proteins to AU rich elements and destabilization of mRNA
46. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
47. Hypoxic stabilisation of vascular endothelial growth factor mRNA by the RNA-binding protein HuR
48. RNA stabilisation by the AU-rich element binding protein, HuR, an ELAV protein
49. HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation
50. The 3′ untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR
51. An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro
52. Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1