Tissue granuloma structure-function in experimental visceral leishmaniasis

International Journal of Experimental Pathology

Volumn 82, Issue 5, 2001, Pages 249-267

  Murray, Henry W ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Box 136 ^*  (United States)

Author keywords

Cytokines; Granuloma; Leishmania donovani; Leishmaniasis; Monocytes; T cells

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; TUMOR NECROSIS FACTOR;

ARTICLE; CELL ACTIVATION; CELL STIMULATION; DISEASE ASSOCIATION; GRANULOMA; HYPERTROPHY; IMMUNE RESPONSE; IMMUNITY; KNOCKOUT MOUSE; MACROPHAGE; NONHUMAN; PARASITE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; T LYMPHOCYTE; VISCERAL LEISHMANIASIS;

ANIMALS; CYTOKINES; GRANULOMA; INTERCELLULAR ADHESION MOLECULE-1; KUPFFER CELLS; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; LIVER DISEASES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; T-LYMPHOCYTES; TH1 CELLS;

EID: 0035570473     PISSN: 09599673     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2613.2001.00199.x     Document Type: Article

References (72)

1. Chemokines. Leucocyte recruitment and activation cytokines
2. The granulomatous inflammatory response
3. Granulomas and cytokines
4. IL-13 in Iranian patients with visceral leishmaniaisis: Relationship to other Th2 and Th1 cytokines
5. Leishmaniasis
6. Is CTLA-4 a master switch for peripheral T cell tolerance?
7. Effector role of blood monocytes in experimental visceral leishmaniasis
8. Cyclophosphamide affects the dynamics of granuloma formation in experimental visceral leishmaniasis
9. Leishmania donovani infection initiates T cell-independent chemokine responses which are subsequently amplified in a T cell-dependent manner
10. Recombinant interleukin-1α augments granuloma formation but not parasite clearance in mice infected with Leishmania donovani
11. Visceral leishmanaisis (kala-azar) in Iran: A pathologic and electron microscopic study
12. Granulomatous inflammation and transmission of infectious disease
13. A novel nonclassic B2-microglobulin-restricted mechanism influencing early lymphocyte accumulation and subsequent resistance to tuberculosis in the lung
14. NOS2-derived nitric oxide regulates the size, quantity and quality of granuloma formation in Mycobacterium avium-infected mice without affecting bacterial loads
15. Liver morphology and function in visceral leishmaniasis
16. An in vivo analysis of cytokine production during Leishmania donovani infection in scid mice
17. Neutralization of IL-12 demonstrates the existence of discrete organ-specific phases in the control of Leishmania donovani
18. Immunopathology of schistosomiasis. A cautionary tale of mice and men
19. In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD41 T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-α
20. TGF- mediates CTLA-4 suppression of cellular immunity in murine kalaazar
21. A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells
22. Pathologic changes in murine leishmaniasis (Leishmania donovani) with special reference to the dynamics of granuloma formation in the liver
23. Inflammatory cytokine production by immunological and foreign body multinucleated giant cells
24. NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease
25. Experimental visceral leishmaniasis: Sequential events of granuloma formation at subcutaneous inoculation site
26. Chemokines - Chemotactic cytokines that mediate inflammation
27. Characterization of tumor necrosis factor- deficient mice
28. Chemokine: The times are a-changin'
29. Dynamics of granuloma formation in experimental visceral leishmaniasis
30. Cytokines in the induction and expression of T-cell-mediate granuloma formation and protection in the murine model of listeriosis
31. Regional differences in the cellular immune response to experimental cutaneous or visceral infection with Leishmania donovani
32. Induction of Th1 and Th2 cell-associated cytokines in experimental visceral leishmaniasis
33. Hepatic fibrin-ring granulomas in visceral leishmaniasis
34. Blockade of CTLA-4 enhances host resistance to the intracellular pathogen, Leishmania donovani
35. Experimental visceral leishmaniasis. Production of interleukin 2 and gamma interferon, tissue immune reaction, and response to treatment with interleukin 2 and gamma interferon
36. Effect of continuous administration of interferon-gamma in experimental visceral leishmaniasis
37. Acquired resistance and granuloma formation in experimental visceral leishmaniasis: Differential T cell and lymphokine roles in initial vs. established immunity
38. Role and effect of interleukin-2 in experimental visceral leishmaniasis
39. Interleukin 12 is effective treatment for an established systemic intracellular infection. Experimental visceral leishmaniasis
40. Intracellular antimicrobial response of the T cell-deficient host to cytokine therapy. Effect of interferon-gamma in experimental visceral leishmaniasis in nude mice
41. Effect of granulocyte-macrophage colony-stimulating factor in experimental visceral leishmaniasis
42. Models of relapse of experimental visceral leishmaniasis
43. Endogenous IL-12 regulates acquired resistance in experimental visceral leishmaniasis
44. Behavior of visceral Leishmania donovani in an experimentally-induced Th2 cell-associated response model
45. Granulomatous inflammation: Host antimicrobial defense in the tissues in visceral leishmaniasis
46. Macrophage microbicidal mechanisms in vivo. Reactive nitrogen vs. oxygen intermediates in the killing of intracellular visceral Leishmania donovani
47. Treatment of visceral leishmaniasis (kalaazar). A decade of progress and future approaches
48. Mononuclear cell recruitment, granuloma assembly, and response to treatment in experimental visceral leishmaniasis. Intracellular adhesion molecule 1-dependent and -independent regulation
49. Role of endogenous gamma interferon and macrophage microbicidal mechanisms in host response to chemotherapy in experimental visceral leishmaniasis
50. Visceral leishmaniasis in mice devoid of tumor necrosis factor and response to treatment
51. Interleukin 12 regulates the response to chemotherapy in experimental visceral leishmaniasis
52. Clinical and experimental advances in treatment in visceral. Leishmaniasis
53. Studies on Mediterranean leishmanaisis. II. An outbreak of visceral leishmaniasis in northern Italy
54. Studies on Mediterranean leishmaniasis. II. Asymptomatic cases of visceral leishmaniasis
55. The regulation of immunity to Leishmania major
56. r congenic mouse strains
57. IL-12 gene-deficient C57BL/6 mice are susceptible to Leishmania donovani but have diminished hepatic pathology
58. Restraining mycobacteria. Role of granulomas in mycobacterial infections
59. The granulomatous inflammatory response
60. Type 1/type 2 immunity in infectious diseases
61. Experimental visceral leishmaniasis. Role of endogenous interferon-gamma in host defense and tissue granulomatous response
62. Role of L3T4+ and Lyt-2+ cells in experimental visceral leishmaniasis
63. Immune-inflammatory mechanisms in IFN- γ-mediated anti-tumor activity
64. Adhesion molecules in lesions of American cutaneous leishmaniasis
65. Intracellular antimicrobial activity in the absence of interferon-γ. Effect of interleukin 12 in experimental visceral leishmanaisis in interferon-γ gene-disrupted mice
66. The role and effect of tumor necrosis factor-alpha in experimental visceral leishmaniasis
67. Morphology of spleen and lymph nodes in fatal visceral leishmaniais
68. A functional classifiction of granulomatous inflammation
69. Granulomatous inflammation - A review
70. Early histopathology of experimental infection with Leishmania donovani in hamsters
71. Local suppression of IFN-γ in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi
72. The importance of TGF- in murine visceral leishmaniasis