Leishmania donovani infection initiates T cell-independent chemokine responses, which are subsequently amplified in a T cell-dependent manner

European Journal of Immunology

Volumn 29, Issue 1, 1999, Pages 203-214

  Cotterell, Sara E J ^a   Engwerda, Christian R ^a   Kaye, Paul M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Chemokine; Infectious immunity parasites; Inflammation; Rodent

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 4; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; LEISHMANIA DONOVANI; LEISHMANIASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHEMOKINE CCL2; CHEMOKINES; CHEMOKINES, CXC; FEMALE; GENE EXPRESSION REGULATION; GRANULOMA; INTERFERON TYPE II; INTERLEUKIN-4; KINETICS; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; LIVER; LIVER DISEASES; MACROPHAGE INFLAMMATORY PROTEIN-1; MICE; MICE, INBRED BALB C; MICE, SCID; MODELS, BIOLOGICAL; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 0032920816     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199901)29:01<203::AID-IMMU203>3.0.CO;2-B     Document Type: Article

References (54)

1. Murray, H. W., Squires, K. E., Miralles, C. D., Stoekle, M. Y., Granger, A. M., Granelli-Piperno, S. and Bodgan, C., Acquired Resistance and Granuloma Formation in Experimental Visceral Leishmaniasis. J. Immunol. 1992. 148: 1858-1863.
2. McElrath, M. J., Murray, H. W. and Cohn, Z. A., The Dynamics of Granuloma Formation in Experimental Visceral Leishmaniasis. J. Exp. Med. 1988. 167: 1927-1937.
3. Murray, H. W., Miralles, G. D., Stoekle, M. Y. and Dermott, D. F., Role and Effect of IL-2 in Experimental Visceral Leishmaniasis. J. Immunol. 1993. 151: 929-938.
4. Murray, H. W., Endogenous Interleukin-12 Regulates Acquired Resistance in Experimental Visceral Leishmaniasis. J. Inf. Diseases 1997. 175: 1477-1479.
5. Tumang, M. C. T., Keogh, C., Moldawer, L. L., Helfgott, D. C., Teitelbaum, R., Hariprashad, J., Murray, H. W., Role and Effect of TNF-α in Experimental Visceral Leishmaniasis. J. Immunol. 1994. 153: 768-775.
6. Squires, K. E., Schreiber, R. D., McElrath, M. J., Rubin, B. Y., Anderson, S. L. and Murray, H. W., Experimental Visceral Leishmaniasis: Role of Endogenous IFN-γ in Host Defence and Tissue Granulomatous Response. J. Immunol. 1989. 143: 4244-4249.
7. Kaye, P. M., Leishmaniasis: immunology, persistence and antigen presentation. Baillieres Clin. Infect. Dis. 1994. 1: 351-366.
8. + Cells In Experimental Visceral Leishmaniasis. J. Immunol. 1990. 140: 3971-3977.
9. Bosma, G. C., Custer, R. P. and Bosma, M. J., A severe combined immunodeficiency in the mouse. Nature 1993. 301: 515-526.
10. Engwerda, C. R., Smelt, S. C. and Kaye, P. M., An In Vivo Analysis of Cytokine Production during Leishmania donovani Infection in scid Mice. Exp. Parasitol. 1996. 84: 195-202.
11. Taub, D. D. and Oppenhiem, J. J., Chemokines, inflammation and the immune system. Ther. Immunol. 1994. 1: 229-246.
12. Rollins, B. J., Chemokines. Blood 1997. 90: 909-928.
13. Oppenhiem, J. J., Zachariae, C. O. C., Mukaida, N. and Matsushima, K., Properties of the novel proinflammatory supergene "intercrine" cytokine family. Annu. Rev. Immunol. 1991. 9: 617-648.
14. Uguccioni, M., D'Apuzzo, M., Loetscher, M., Dewald, B. and Baggiolini, M., Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1α and MIP-1β on human monocytes. Eur. J. Immunol. 1995. 25: 64-68.
15. Roth, S. J., Woldemar-Carr, M. and Springer, T. A., C-C chemokines, but not the C-X-C chemokines interleukin-8 and interferon-γ inducible protein-10, stimulate transendothelial chemotaxis of T lymphocytes. Eur. J. Immunol. 1995. 25: 3482-3488.
16. Carr, M. W., Roth, S. J., Luther, E., Rose, S. S. and Springer, T. A., Monocyte Chemoattractant Protein 1 acts as a T-lymphocyte chemoattractant. Proc. Natl. Acad. SCI. USA 1994. 91: 3652-3656.
17. Gao, J.-L., Wynn, T. A., Chung, Y., Lee, E. J., Broxmeyer, H. E., Cooper, S., Tiffany, H. L., Westphal, H., Kwon-Chung, J. and Murphy, P. M., Impaired Host Defense, Haematopoiesis, Granulomatous Inflammation and Type 1-Type2 Cytokine Balance in Mice Lacking CC Chemokine Receptor 1. J. Exp. Med. 1997. 185: 1959-1968.
18. Tessier, P. A., Naccache, P. H., Clark-Lewis, I., Gladue, R. P., Neote, K. S. and McColl, S. R., Chemokine Networks In Vivo. Involvement of C-X-C and C-C Chemokines in Neutrophil Extravasation in Response to TNF-α. J. Immunol. 1997. 159: 3595-3602.
19. Huffnagle, G. B., Streiter, R. M., Standiford, T. J., McDonald, R. A., Burdick, M. D., Kunkel, S. L. and Toews, G. B., The Role of Monocyte Chemotactic Protein-1 (MCP-1) in the Recruitment of Monocytes and CD4+ T Cells During a Pulmonary Cryptococcus neoformans Infection. J. Immunol. 1995. 155: 4790-4797.
20. Doyle, H. A. and Murphy, J. W., MIP1α contributes to the anticryptococcal delayed-type hypersensitivity reaction and protection against Cryptococcus neoformans. J. Leuk. Biol. 1997. 61: 147-155.
21. Siveke, J. T. and Hamann, A., T Helper 1 and T Helper 2 Cells Respond Differentially to Chemokines. J. Immunol. 1998. 160: 550-554.
22. Bonecchi, R., Bianchi, G., Bordignon, P. P., D'Ambrosio, D., Lang, R., Alessandro Borsatti, Sozzani, S., Allavena, P., Gray, P. A., Mantovani, A. and Sinigaglia, F., Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s. J. Exp. Med. 1998. 187: 129-134.
23. Dewald, B., Moser, B., Barella, L., Schumacher, C., Baggiolini, M. and Clark-Lewis, I., IP-10, a γ-interferon-inducible protein related to interleukin-8, lacks neutrophil activating properties. Immunol. Lett. 1992. 32: 81-84.
24. Taub, D. D., Lloyd, A. R., Conlon, K., Wang, J. M., Ortaldo, J. R., Harada, A., Matsushima, K., Kelvin, D. J. and Oppenhiem, J. J., Recombinant Human Interferon-inducible Protein 10 Is a Chemoattractant for Human Monocytes and T Lymphocytes and Promotes T cell Adhesion to Endothelial Cells. J. Exp. Med. 1993. 177: 1809-1814.
25. Taub, D. D., Longo, D. L. and Murphy, W. J., Human Interferon-Inducible Protein-10 Induces Mononuclear Cell Infiltration in Mice and Promotes the Migration of Human T Lymphocytes Into the Peripheral Tissues of Human Peripheral Blood Lymphocytes-SCID Mice. Blood 1996. 87: 1423-1431.
26. Chensue, S. W., Warmington, K. S., Ruth, J. H., Sanghi, P. S., Lincoln, P. and Kunkel, S. L., Role of Monocyte Chemoattractant Protein-1 (MCP-1) in Th1 (Mycobacterial) and Th2 (Schistosomal) Antigen-Induced Granuloma Formation Relationship to Local Inflammation, Th Cell Expression, and IL12 Production. J. Immunol. 1996. 157: 4602-4608.
27. Standiford, T. J., Kunkel, S. T., Greenburger, M. J., Laichalk, L. L. and Streiter, R. M., Expression and regulation of chemokines in bacterial pneumonia. J. Leuk. Biol. 1996. 59: 24-28.
28. Seebach, J., Bartholdi, D., Frei, K., Spanaus, K.-S., Ferrero, E., Widmer, U., Isenmann, S., Streiter, R. M., Schwab, M., Pfister, H.-W. and Fontana, A., Experimental Listeria Meningocephalitis. Macrophage Inflammatory Protein-1α and -2 Are Produced Intrathecally and Mediate Chemotactic Activity in Cerebrospinal Fluid and Infected Mice. J. Immunol. 1995. 155: 4367-4375.
29. Carrera, L., Gazzinelli, R. T., Badolato, R., Hieny, S., Muller, W., Kuhn, R. and Sacks, D. L., Leishmania Promastigotes Selectively Inhibit Interleukin 12 Induction in Bone Marrow-derived Macrophages from Susceptible and Resistant Mice. J. Exp. Med. 1996. 183: 515-526.
30. Racoosin, E. L. and Beverley, S. M., Leishmania major: Promastigotes Induce Expression of a Subset of Chemokine Genes in Murine Macrophages. Exp. Parasitol. 1997. 85: 283-295.
31. Ritter, U., Moll, H., Laskay, T., Brocker, E.-B., Velazco, O., Becker, I. and Gillitzer, R., Differential Expression of Chemokines in Patients with Localized and Diffuse Cutaneous American Leishmaniasis. J. Infect. Dis. 1996. 173: 699-709.
32. + T cells Induces Monocyte Chemoattractant Protein-1 in Early Listeriosis. J. Immunol. 1997. 159: 7-10.
33. + T cells which are NK1.1 . Eur. J. Immunol. 1995. 25: 3298-3307.
34. Chace, J. H., Cowdery, J. S. and Field, E. E., Effect of Anti-CD4 on CD4 subsets I. Anti-CD4 Preferentially Deletes Resting, Naive CD4 Cells and Spares Activated CD4 Cells. J. Immunol. 1994. 152: 405-412.
35. Mosser, D. M. and Rosenthal, L. A., Divergent Strategies used by the promastigote and amastigote forms of Leishmania to invade mammalian cells. Baillieres Clin. Infect. Dis. 1994. 1: 191-212.
36. Perera, P.-Y., Vogel, S. N., Detore, G. R., Haziot, A. and Goyert, S. M., CD14-Dependent and CD14-Independent Signalling Pathways in Murine Macrophages for Normal and CD-14 Knockout Mice Stimulated with Lipopolysaccharide or Taxol. J. Immunol. 1997. 158: 4422-4429.
37. Badolato, R., Sacks, D. L., Savola, D. and Musso, T., Leishmania major: Infection of Human Monocytes Induces Expression of IL-8 and MCAF. Exp. Para. 1996. 82: 21-26.
38. + T Cells during Initiation of Infection. J. Exp. Med. 1994. 179: 456-477.
39. Gorak, P. M. A., Engwerda, C. R. and Kaye, P. M., Dendritic cells, but not macrophages, produce IL-12 immediately following Leishmania donovani infection. J. Immunol. 1997. 159: 4460-4466.
40. Mohamadzadeh, M., Poltorak, A. N., Bergstresser, P. R., Beutler, B. and Takashima, A., Dendritic Cells produce Macrophage Inflammatory Protein-1γ, a New Member of the CC Chemokine Family. J. Immunol. 1996. 156: 3102-3106.
41. Adema, G. J., Hartgers, F., Verstaten, R., de Vries, E., Marland, G., Menon, S., Foster, J., Xu, Y., Nooyen, P., McClanahan, T., Bacon, K. B. and Figdor, C. G., A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature 1997. 387: 713-717.
42. + T Lymphocytes in IFN-γ Production and Protective Immunity Induced by an Attenuated Toxoplasma gondii Vaccine. J. Immunol. 1991. 146: 286-292.
43. Ohteki, T. and MacDonald, H. R., Major histocompatibility complex class I related molecules control the development of CD4+ 8- and CD4- 8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice. J. Exp. Med. 1994. 180: 699-704.
44. Gatass, C. R., King, L. B., Luster, A. D. and Ashwell, J. D., Constitutive Expression of Interferon γ-inducible Protein 10 in Lymphoid Organs and Inducible Expression in T cells and Thymocytes. J. Exp. Med. 1994. 179: 1373-1378.
45. Zipfel, P. F., Bialonski, A. and Skerka, C., Induction of Members of the IL-8/NAP-1 Gene Family in Human T Lymphocytes is Suppressed by Cyclosporin A. Biochem. Biophys. Res. Comm. 1991. 181: 179-183.
46. Narumi, S., Wyner, L. M., Stoler, M. H., Tannenbaim, C. S. and Hamilton, T. A., Tissue-specific expression of murine IP-10 mRNA following systemic treatment with interferon γ. J. Leuk. Biol. 1992. 52: 27-33.
47. Amichay, D., Gazzinelli, R. T., Karupiah, G., Moench, T. R., Sher, A. and Farber, J. M., Genes for Chemokines MuMig and Crg-2 Are Induced in Protozoan and Viral Infections in Response to IFN-γ with Patterns of Tissue Expression That Suggest Nonredundant Roles In Vivo. J. Immunol. 1996. 157: 4511-4520.
48. Smelt, S. C., Engwerda, C. R., McCrossen, M. and Kaye, P. M., Destruction of Follicular Dendritic Cells During Chronic Visceral Leishmaniasis. J. Immunol. 1997. 158: 3813-3821.
49. Culley, F. J., Harris, R. A., Kaye, P. M., McAdam, K. P. and Raynes, J. G., C-reactive protein binds to a novel ligand on Leishmania donovani and increases uptake into human macrophages. J. Immunol. 1996. 156: 4691-4696.
50. Stauber, L. A., Host resistance to the Khartoum strain of Leishmania donovani. Rice Inst. Pam. 1958. 45: 80-86.
51. Svetic, A., Finkelman, F. D., Jian, Y. C., Dieffenbach, C. W., Scott, D. E., Mccarthy, K. F., Steinberg, A. D. and Gause, W. C., Cytokine Gene Expression after in vivo Primary Immunisation with Goat Antibody to Mouse IgD Antibody. J. Immunol. 1991. 147: 2391-2397.
52. Thoades, E. R., Cooper, A. M. and Orme, I. M., Chemokine Response in Mice Infected with Mycobacterium tuberculosis. Infect. Immun. 1995. 63: 3871-3877.
53. Sonouchi, K., Hamilton, T. A., Tannenbaum, C. S., Tubbs, R. R., Bukowski, R. and Finke, J., Chemokine Gene Expression in the Murine Renal Cell Carcinoma, RENCA, following treatment In Vivo with Interferon-α and Interleukin-2. Am. J. Path. 1994. 144: 747-755.
54. Murphy, M. L., Engwerda, C. R., Gorak, P. A. and Kaye, P. M., B7-1 Blockade Enhances T Cell Responses to Leishmania donovani. J. Immunol. 1997. 159: 4460-4466.