메뉴 건너뛰기




Volumn 185, Issue 7, 1997, Pages 1231-1239

Intracellular antimicrobial activity in the absence of interferon-γ: Effect of interleukin-12 in experimental visceral Leishmaniasis in interferon-γ gene-disrupted mice

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

EID: 0030895747     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.7.1231     Document Type: Article
Times cited : (148)

References (45)
  • 1
    • 0024805717 scopus 로고
    • Experimental visceral leishmaniasis: Role of endogenous IFN-γ in host defense and tissue granulomatous response
    • Squires, K.E., R.D. Schreiber, M.J. McElrath, B.Y. Rubin, S.L. Anderson, and H.W. Murray. 1989. Experimental visceral leishmaniasis: role of endogenous IFN-γ in host defense and tissue granulomatous response. J. Immunol. 143:4244-4249.
    • (1989) J. Immunol. , vol.143 , pp. 4244-4249
    • Squires, K.E.1    Schreiber, R.D.2    McElrath, M.J.3    Rubin, B.Y.4    Anderson, S.L.5    Murray, H.W.6
  • 2
    • 0025266647 scopus 로고
    • Effect of continuous administration of interferon-γ in experimental visceral leishmaniasis
    • Murray, H.W. 1990. Effect of continuous administration of interferon-γ in experimental visceral leishmaniasis. J. Infect. Dis. 161:992-994.
    • (1990) J. Infect. Dis. , vol.161 , pp. 992-994
    • Murray, H.W.1
  • 4
    • 0027485028 scopus 로고
    • Response to influenza infection in mice with a targeted disruption in the interferon-γ gene
    • Graham, M.B., D.K. Dalton, D. Giltinan, V.L. Braciale, T.A. Stewart, and T.J. Braciale. 1993. Response to influenza infection in mice with a targeted disruption in the interferon-γ gene. J. Exp. Med. 178:1725-1732.
    • (1993) J. Exp. Med. , vol.178 , pp. 1725-1732
    • Graham, M.B.1    Dalton, D.K.2    Giltinan, D.3    Braciale, V.L.4    Stewart, T.A.5    Braciale, T.J.6
  • 6
    • 0028670487 scopus 로고
    • Interferon-γ-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major
    • Wang, Z., S. Zheng, D. Corry, D.K. Dalton, R.A. Seder, S.L. Reiner, and R.M. Locksley. 1994. Interferon-γ-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major. Proc. Natl. Acad. Sci. USA. 91:12932-12936.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12932-12936
    • Wang, Z.1    Zheng, S.2    Corry, D.3    Dalton, D.K.4    Seder, R.A.5    Reiner, S.L.6    Locksley, R.M.7
  • 7
    • 0028326103 scopus 로고
    • + effector cells default to the Th2 pathway in interferon-γ-deficient mice infected with Leishmania major
    • + effector cells default to the Th2 pathway in interferon-γ-deficient mice infected with Leishmania major. J. Exp. Med. 179:1367-1371.
    • (1994) J. Exp. Med. , vol.179 , pp. 1367-1371
    • Wang, Z.1    Reiner, S.L.2    Sheng, S.3    Dalton, D.K.4    Locksley, R.M.5
  • 8
    • 0028356910 scopus 로고
    • Anti-immunoglobulin E treatment decreases worm burden and egg production in Schistosoma mansoni-infected normal and interferon-γ knockout mice
    • Amiri, P., M. Haak-Frendscho, K. Robbins, J.H. McKerrow, T. Stewart, and P. Jardieu. 1994. Anti-immunoglobulin E treatment decreases worm burden and egg production in Schistosoma mansoni-infected normal and interferon-γ knockout mice. J. Exp. Med. 180:43-51.
    • (1994) J. Exp. Med. , vol.180 , pp. 43-51
    • Amiri, P.1    Haak-Frendscho, M.2    Robbins, K.3    McKerrow, J.H.4    Stewart, T.5    Jardieu, P.6
  • 10
    • 0028950126 scopus 로고
    • Interleukin-12 is effective treatment for an established systemic intracellular infection: Experimental visceral leishmaniasis
    • Murray, H.W., and J. Hariprashad. 1995. Interleukin-12 is effective treatment for an established systemic intracellular infection: experimental visceral leishmaniasis. J. Exp. Med. 181: 387-391.
    • (1995) J. Exp. Med. , vol.181 , pp. 387-391
    • Murray, H.W.1    Hariprashad, J.2
  • 11
    • 0023145125 scopus 로고
    • Experimental visceral leishnianiasis: Production of interleukin 2 and interferon-γ, tissue immune reaction, and response to treatment with interleukin 2 and interferon-γ
    • Murray, H.W., J.J. Stern, K. Welte, B.Y. Rubin, S.M. Carriero, and C.F. Nathan. 1987. Experimental visceral leishnianiasis: production of interleukin 2 and interferon-γ, tissue immune reaction, and response to treatment with interleukin 2 and interferon-γ. J. Immunol. 138:2290-2297.
    • (1987) J. Immunol. , vol.138 , pp. 2290-2297
    • Murray, H.W.1    Stern, J.J.2    Welte, K.3    Rubin, B.Y.4    Carriero, S.M.5    Nathan, C.F.6
  • 12
    • 0028940930 scopus 로고
    • Effect of granulocyte-macrophage colony-stimulating factor in experimental visceral leishmaniasis
    • Murray, H.W., J.S. Cervia, J. Hariprashad, A.P. Taylor, M.Y. Stoeckle, and H. Hockman. 1995. Effect of granulocyte-macrophage colony-stimulating factor in experimental visceral leishmaniasis. J. Clin. Invest. 95:1183-1192.
    • (1995) J. Clin. Invest. , vol.95 , pp. 1183-1192
    • Murray, H.W.1    Cervia, J.S.2    Hariprashad, J.3    Taylor, A.P.4    Stoeckle, M.Y.5    Hockman, H.6
  • 14
    • 0028129526 scopus 로고
    • Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major
    • Stenger, S., H. Thuring, M. Rolinghoff, and C. Bogdan. 1994. Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J. Exp. Med. 180:783-793.
    • (1994) J. Exp. Med. , vol.180 , pp. 783-793
    • Stenger, S.1    Thuring, H.2    Rolinghoff, M.3    Bogdan, C.4
  • 16
    • 0028936417 scopus 로고
    • Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuherculosis
    • Chan, J., K. Tanaka, D. Carroll, J. Flynn, and B.R. Bloom. 1995. Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuherculosis. Infect. Immun. 63:730-740.
    • (1995) Infect. Immun. , vol.63 , pp. 730-740
    • Chan, J.1    Tanaka, K.2    Carroll, D.3    Flynn, J.4    Bloom, B.R.5
  • 17
    • 0023678603 scopus 로고
    • Dynamics of granuloma fomiation in experimental visceral leishmaniasis
    • McElrath, M.J., H.W. Murray, and Z.A. Cohn. 1988. Dynamics of granuloma fomiation in experimental visceral leishmaniasis. J. Exp. Med. 167:1927-1937.
    • (1988) J. Exp. Med. , vol.167 , pp. 1927-1937
    • McElrath, M.J.1    Murray, H.W.2    Cohn, Z.A.3
  • 18
    • 0027164877 scopus 로고
    • Role and effect of IL-2 in experimental visceral leishmaniasis
    • Murray, H.W., G.D. Miralles, M.Y. Stoeckle, and D.F. McDermott. 1993. Role and effect of IL-2 in experimental visceral leishmaniasis. J. Immunol. 151:929-938.
    • (1993) J. Immunol. , vol.151 , pp. 929-938
    • Murray, H.W.1    Miralles, G.D.2    Stoeckle, M.Y.3    McDermott, D.F.4
  • 19
    • 0027264849 scopus 로고
    • Interleukin-12 is required for the T-lymphocyte-independent induction of interferon-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts
    • Gazzinelli, R., S. Hieny, T.A. Wynn, S. Wolf, and A. Sher. 1993. Interleukin-12 is required for the T-lymphocyte-independent induction of interferon-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc. Natl. Acad. Sci. USA. 90:6115-6119.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6115-6119
    • Gazzinelli, R.1    Hieny, S.2    Wynn, T.A.3    Wolf, S.4    Sher, A.5
  • 20
    • 0028231754 scopus 로고
    • Endogenous interleukin-12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology
    • Wynn, T.A., I. Eltoum, I. Oswald, A.W. Cheever, and A. Sher. 1994. Endogenous interleukin-12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J. Exp. Med. 179:1551-1561.
    • (1994) J. Exp. Med. , vol.179 , pp. 1551-1561
    • Wynn, T.A.1    Eltoum, I.2    Oswald, I.3    Cheever, A.W.4    Sher, A.5
  • 21
    • 0027491655 scopus 로고
    • + T cells to enhance priming for interferon-γ production and diminishes interleukin 4 inhibition of such priming
    • + T cells to enhance priming for interferon-γ production and diminishes interleukin 4 inhibition of such priming. Proc. Natl. Acad. Sci. USA. 90:10188-10192.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10188-10192
    • Seder, R.A.1    Gazzinelli, R.2    Sher, A.3    Paul, W.E.4
  • 22
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridges innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridges innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251-162.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-1162
    • Trinchieri, G.1
  • 24
    • 0028012527 scopus 로고
    • Interleukin-12
    • Brunda, M.J. 1994. Interleukin-12. J. Leuk. Biol. 55:280-288.
    • (1994) J. Leuk. Biol. , vol.55 , pp. 280-288
    • Brunda, M.J.1
  • 25
    • 0027199734 scopus 로고
    • + natural killer cells stimulated with interleukin-2, interleukin-7, and interleukin-12
    • + natural killer cells stimulated with interleukin-2, interleukin-7, and interleukin-12. Eur. J. Immunol. 23:1831-1838.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1831-1838
    • Naume, B.1    Johnsen, A.C.2    Espevik, T.3    Sondam, A.4
  • 26
    • 0025300228 scopus 로고
    • Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine
    • Liew, F.Y., S. Millott, C. Parkinson, R.M. Palmer, and S. Moncada. 1990. Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine. J. Immunol. 144:4794-4797.
    • (1990) J. Immunol. , vol.144 , pp. 4794-4797
    • Liew, F.Y.1    Millott, S.2    Parkinson, C.3    Palmer, R.M.4    Moncada, S.5
  • 27
    • 0025191159 scopus 로고
    • Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism
    • Green, S.J., M.S. Meltzer, J.B. Hibbs, and C.A. Nacy. 1990. Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism. J. Immunol. 144:278-283.
    • (1990) J. Immunol. , vol.144 , pp. 278-283
    • Green, S.J.1    Meltzer, M.S.2    Hibbs, J.B.3    Nacy, C.A.4
  • 28
    • 0028142783 scopus 로고
    • Role of gamma interferon and tumor necrosis factor alpha during T-cell-independent and -dependent phases of Mycobacterium avium infection
    • Appelberg, R., A.G. Castro, J. Pedrosa, R.A. Silva, I.M. Orme, and P. Minoprio. 1994. Role of gamma interferon and tumor necrosis factor alpha during T-cell-independent and -dependent phases of Mycobacterium avium infection. Infect. Immun. 62:3962-3971.
    • (1994) Infect. Immun. , vol.62 , pp. 3962-3971
    • Appelberg, R.1    Castro, A.G.2    Pedrosa, J.3    Silva, R.A.4    Orme, I.M.5    Minoprio, P.6
  • 29
    • 0027931611 scopus 로고
    • Selective Mycobacterium avium - Induced production of nitric oxide by human monocyte-derived macrophages
    • Dumarey, C.H., V. Labrousse, N. Rastogi, B.B. Vargaftig, and M. Bachelet. 1994. Selective Mycobacterium avium - induced production of nitric oxide by human monocyte-derived macrophages. J. Leuk. Biol. 56:36-40.
    • (1994) J. Leuk. Biol. , vol.56 , pp. 36-40
    • Dumarey, C.H.1    Labrousse, V.2    Rastogi, N.3    Vargaftig, B.B.4    Bachelet, M.5
  • 30
    • 0025940127 scopus 로고
    • Role of inorganic nitrogen oxides and tumor necrosis factor-alpha in killing Leishmania donovani amastigotes in gamma-interferon lipopolysaccharide-activated macrophages from Lshs and Lshr congenic mouse strains
    • Roach, T.I., A.F. Kiderlen, and J.M. Blackwell. 1991. Role of inorganic nitrogen oxides and tumor necrosis factor-alpha in killing Leishmania donovani amastigotes in gamma-interferon lipopolysaccharide-activated macrophages from Lshs and Lshr congenic mouse strains. Infect. Immun. 59:3935-3944.
    • (1991) Infect. Immun. , vol.59 , pp. 3935-3944
    • Roach, T.I.1    Kiderlen, A.F.2    Blackwell, J.M.3
  • 31
    • 0028266398 scopus 로고
    • Depletion of gamma interferon and tumor necrosis factor-alpha in mice with Rickettsia conorii-infected endothelium: Impairment of rickettsicidal nitric oxide production resulting in fatal, overwhelming rickettsial disease
    • Feng, H., V.L. Popov, and D.H. Walker. 1994. Depletion of gamma interferon and tumor necrosis factor-alpha in mice with Rickettsia conorii-infected endothelium: impairment of rickettsicidal nitric oxide production resulting in fatal, overwhelming rickettsial disease. Infect. Immun. 62:1952-1960.
    • (1994) Infect. Immun. , vol.62 , pp. 1952-1960
    • Feng, H.1    Popov, V.L.2    Walker, D.H.3
  • 32
    • 0018704363 scopus 로고
    • Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates
    • Murray, H.W., C.W. Juangbhanich, C.F. Nathan, and Z.A. Cohn. 1979. Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates. J. Exp. Med. 150: 950-964.
    • (1979) J. Exp. Med. , vol.150 , pp. 950-964
    • Murray, H.W.1    Juangbhanich, C.W.2    Nathan, C.F.3    Cohn, Z.A.4
  • 34
    • 0019978017 scopus 로고
    • Cell-mediated immune response in experimental visceral leishmaniasis. II. Oxygen-independent killing of intracellular Leishmania donovani
    • Murray, H.W. 1982. Cell-mediated immune response in experimental visceral leishmaniasis. II. Oxygen-independent killing of intracellular Leishmania donovani. J. Immunol. 129: 351-357.
    • (1982) J. Immunol. , vol.129 , pp. 351-357
    • Murray, H.W.1
  • 35
    • 0026549480 scopus 로고
    • Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages
    • Chan, J., Y. Xing, R.S. Magliosso, and B.R. Bloom. 1992. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J. Exp. Med. 175:1111-1122.
    • (1992) J. Exp. Med. , vol.175 , pp. 1111-1122
    • Chan, J.1    Xing, Y.2    Magliosso, R.S.3    Bloom, B.R.4
  • 36
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan, C. 1992. Nitric oxide as a secretory product of mammalian cells. FASEB J. 6:3051-3064.
    • (1992) FASEB J. , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 37
    • 0025847642 scopus 로고
    • Tumor necrosis factor-alpha: Central regulatory cytokine in the induction of macrophage antimicrobial activities
    • Nacy, C.A. A.I. Meierovics, M. Belosevic, and S.J. Green. 1991. Tumor necrosis factor-alpha: central regulatory cytokine in the induction of macrophage antimicrobial activities. Pathobiology. 59:182-184.
    • (1991) Pathobiology , vol.59 , pp. 182-184
    • Nacy, C.A.1    Meierovics, A.I.2    Belosevic, M.3    Green, S.J.4
  • 39
    • 0025309606 scopus 로고
    • TNF-α mediates host protection against cutaneous leishmaniasis
    • Liew, F.Y., C. Parkinson, S. Millott, A. Severn, and M. Carrier. 1990. TNF-α mediates host protection against cutaneous leishmaniasis. Immunology. 69:570-573.
    • (1990) Immunology , vol.69 , pp. 570-573
    • Liew, F.Y.1    Parkinson, C.2    Millott, S.3    Severn, A.4    Carrier, M.5
  • 40
    • 0029078676 scopus 로고
    • IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection
    • Flynn, J.L., M.M. Goldstein, K.J. Triebold, J. Sypek, S. Wolf, and B. Bloom. 1995. IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection. J. Immunol. 155:2515-2524.
    • (1995) J. Immunol. , vol.155 , pp. 2515-2524
    • Flynn, J.L.1    Goldstein, M.M.2    Triebold, K.J.3    Sypek, J.4    Wolf, S.5    Bloom, B.6
  • 41
    • 0030294163 scopus 로고    scopus 로고
    • In the absence of endogenous IFN-γ, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection
    • Scharton-Kersten, T.M., T.A. Wynn, E.Y. Denkers, S. Bala, E. Grunvald, S. Heiny, R.T. Gazzinelli, and A. Sher. 1996. In the absence of endogenous IFN-γ, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection. J. Immunol. 157:4045-4054.
    • (1996) J. Immunol. , vol.157 , pp. 4045-4054
    • Scharton-Kersten, T.M.1    Wynn, T.A.2    Denkers, E.Y.3    Bala, S.4    Grunvald, E.5    Heiny, S.6    Gazzinelli, R.T.7    Sher, A.8
  • 44
    • 0027511113 scopus 로고
    • Neutralization of gamma interferon and tumor necrosis factor-alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francisella tularensis infection in Mycobacterium bovis BCG-treated mice
    • Green, S.J., C.A. Nacy, R.D. Schrieiber, D.L. Granger, R.M. Crawford, M.S. Meltzer, and A.H. Fortier. 1993. Neutralization of gamma interferon and tumor necrosis factor-alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francisella tularensis infection in Mycobacterium bovis BCG-treated mice. Infect. Immun. 61:689-698.
    • (1993) Infect. Immun. , vol.61 , pp. 689-698
    • Green, S.J.1    Nacy, C.A.2    Schrieiber, R.D.3    Granger, D.L.4    Crawford, R.M.5    Meltzer, M.S.6    Fortier, A.H.7
  • 45
    • 0029133459 scopus 로고
    • Specific immunity to Listeria monocytogenes in the absence of IFNγ
    • Harty, J.T., and M.J. Bevan. 1995. Specific immunity to Listeria monocytogenes in the absence of IFNγ. Immunity. 3:109-117.
    • (1995) Immunity , vol.3 , pp. 109-117
    • Harty, J.T.1    Bevan, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.