Biospecific interaction analysis: A tool for drug discovery and development

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice

Volumn 1, Issue 2, 2001, Pages 119-135

  Gambari, Roberto ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; DRUG DELIVERY SYSTEM; DRUG DESIGN; HUMAN; INSTRUMENTATION; METHODOLOGY; PHARMACEUTICS; PROTEIN ANALYSIS; REVIEW; STATISTICS; SURFACE PLASMON RESONANCE;

ANIMALS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HUMANS; PROTEIN INTERACTION MAPPING; SURFACE PLASMON RESONANCE; TECHNOLOGY, PHARMACEUTICAL;

EID: 0035552385     PISSN: 11752203     EISSN: None     Source Type: Journal    
DOI: 10.2165/00129785-200101020-00005     Document Type: Review

References (157)

1. 1. D.J. Reen 1994 Enzyme-linked immunosorbent assay (ELISA) Methods Mol Biol 32 461 6 7951745 1:CAS:528:DyaK2cXmsFSnsro%3D Reen DJ. Enzyme-linked immunosorbent assay (ELISA). Methods Mol Biol 1994; 32: 461–6
2. 2. K. Padget A.D. Pearson C.A. Austin 2000 Quantitation of DNA topoisomerase II alpha and beta in human leukaemia cells by immunoblotting Leukemia 14 11 1997 2005 11069037 1:CAS:528:DC%2BD3cXosVeisrY%3D 10.1038/sj.leu.2401928 Padget K, Pearson AD, Austin CA. Quantitation of DNA topoisomerase II alpha and beta in human leukaemia cells by immunoblotting. Leukemia 2000; 14(11): 1997–2005
3. 3. J. Carey 1991 Gel retardation Methods Enzymology 208 103 17 1:CAS:528:DyaK38XisV2mtrw%3D 10.1016/0076-6879(91)08010-F Carey J. Gel retardation. Methods Enzymology 1991; 208: 103–17
4. 4. G. Feriotto A. Ciucci C. Mischiati 1994 Binding of Epstein-Barr virus nuclear antigen 1 to DNA: inhibition by distamycin and two novel distamycin analogues Eur J Pharmacol 267 143 9 8050475 1:CAS:528:DyaK2cXkvF2it7w%3D 10.1016/0922-4106(94)90165-1 Feriotto G, Ciucci A, Mischiati C, et al. Binding of Epstein-Barr virus nuclear antigen 1 to DNA: inhibition by distamycin and two novel distamycin analogues. Eur J Pharmacol 1994; 267: 143–9
5. 5. G. Feriotto C. Mischiati R. Gambari 1994 Sequence-specific recognition of the HIV-1 long terminal repeat by distamycin: a DNase I footprinting study Biochem J 299 451 8 8172606 1:CAS:528:DyaK2cXitlGmsLs%3D Feriotto G, Mischiati C, Gambari R. Sequence-specific recognition of the HIV-1 long terminal repeat by distamycin: a DNase I footprinting study. Biochem J 1994; 299: 451–8
6. 6. C. Mischiati M. Borgatti N. Bianchi 1999 Interaction of the human NF-kappaB p52 transcription factor with DNA-PNA hybrids mimicking the NF-kappaB binding sites of the human immunodeficiency virus type 1 promoter J Biol Chem 274 46 33114 22 10551882 1:CAS:528:DyaK1MXntlynsr4%3D 10.1074/jbc.274.46.33114 Mischiati C, Borgatti M, Bianchi N, et al. Interaction of the human NF-kappaB p52 transcription factor with DNA-PNA hybrids mimicking the NF-kappaB binding sites of the human immunodeficiency virus type 1 promoter. J Biol Chem 1999; 274(46): 33114–22
7. 7. M.P. Byfield R.A. Abuknesha 1994 Biochemical aspects of biosensors Biosensors Electronics 9 373 400 1:CAS:528:DyaK2cXlvF2rs78%3D 10.1016/0956-5663(94)80038-3 Byfield MP, Abuknesha RA. Biochemical aspects of biosensors. Biosensors Electronics 1994; 9; 373–400
8. 8. G.A. Evtugyn H.C. Budnikov N. Kolskaya 1998 Sensitivity and selectivity of electrochemical enzyme sensors for inhibitor determination Talanta 46 465 84 18967167 1:CAS:528:DyaK1cXks1Knur4%3D 10.1016/S0039-9140(97)00313-5 Evtugyn GA, Budnikov HC, Kolskaya N. Sensitivity and selectivity of electrochemical enzyme sensors for inhibitor determination. Talanta 1998; 46: 465–84
9. 9. G. Marko-Varga J. Emneus L. Gorton 1995 Development of enzyme-based amperometric sensors for the determination of phenolic compounds Trends Anal Chem 14 319 28 1:CAS:528:DyaK2MXnt1ansrs%3D Marko-Varga G, Emneus J, Gorton L. Development of enzyme-based amperometric sensors for the determination of phenolic compounds. Trends Anal Chem 1995; 14: 319–28
10. 10. J.M. Emon Van V. Lopez-Avila 1992 Immunochemical methods for environmental analysis Anal Chem 64 79 88 10.1021/ac00026a715 VanEmon JM, Lopez-Avila V. Immunochemical methods for environmental analysis. Anal Chem 1992; 64: 79–88
11. 11. I. Karube 1990 Microbial sensor J Biotechnol 15 255 66 1367462 1:CAS:528:DyaK3cXls1yhtL8%3D 10.1016/0168-1656(90)90031-6 Karube I. Microbial sensor. J Biotechnol 1990; 15: 255–66
12. 12. J. Davies 1994 Surface Plasmon resonance — the technique and its applications to biomaterial processes Nanobiology 3 5 16 1:CAS:528:DyaK2cXlvF2rtr4%3D Davies J. Surface Plasmon resonance — the technique and its applications to biomaterial processes. Nanobiology 1994; 3: 5–16
13. 13. U. Jonsson L. Fagerstam B. Ivarsson 1991 Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology Bio-Techniques 11 620 7 1:STN:280:DyaK383gslGntA%3D%3D Jonsson U, Fagerstam L, Ivarsson B, et al. Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology. Bio-Techniques 1991; 11: 620–7
14. 14. B. Johnsson S. Lofas G. Lindquist 1991 Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors Anal Biochem 198 2 268 77 1724720 1:CAS:528:DyaK3MXmslCrsb4%3D 10.1016/0003-2697(91)90424-R Johnsson B, Lofas S, Lindquist G. Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors. Anal Biochem 1991; 198(2): 268–77
15. 15. R. Karlsson H. Roos L. Fagerstam 1994 Kinetic and concentration analysis using BIA technology Methods 6 99 110 1:CAS:528:DyaK2cXmt1Gls74%3D 10.1006/meth.1994.1013 Karlsson R, Roos H, Fagerstam L, et al. Kinetic and concentration analysis using BIA technology. Methods 1994; 6: 99–110
16. 16. U. Jonsson L. Fagerstam S. Lofas 1993 Introducing a biosensor based technology for real-time biospecific interaction analysis Ann Biol Clin (Paris) 51 1 19 26 1:STN:280:DyaK3szjt1aksA%3D%3D Jonsson U, Fagerstam L, Lofas S, et al. Introducing a biosensor based technology for real-time biospecific interaction analysis. Ann Biol Clin (Paris) 1993; 51(1): 19–26
17. 17. M. Malmqvist 1993 Biospecific interactions analysis using biosensor technology Nature 361 186 7 7678451 1:STN:280:DyaK3s7jtlehtA%3D%3D 10.1038/361186a0 Malmqvist M. Biospecific interactions analysis using biosensor technology. Nature 1993; 361: 186–7
18. 18. P. Nilsson B. Persson M. Uhlén 1995 Real-time monitoring of DNA manipulations using biosensor technology Anal Biochem 224 400 8 7710099 1:CAS:528:DyaK2MXjtFOrtr0%3D 10.1006/abio.1995.1057 Nilsson P, Persson B, Uhlén M, et al. Real-time monitoring of DNA manipulations using biosensor technology. Anal Biochem 1995; 224: 400–8
19. 19. C.M. Niemeyer L. Boldt B. Ceyhan 1999 DNA-Directed immobilization: efficient, reversible, and site-selective surface binding of proteins by means of covalent DNA-streptavidin conjugates Anal Biochem 268 1 54 63 10036162 1:CAS:528:DyaK1MXht1Oqs70%3D 10.1006/abio.1998.3017 Niemeyer CM, Boldt L, Ceyhan B, et al. DNA-Directed immobilization: efficient, reversible, and site-selective surface binding of proteins by means of covalent DNA-streptavidin conjugates. Anal Biochem 1999; 268(1): 54–63
20. 20. G. Feriotto M. Lucci N. Bianchi 1999 Detection of the ΔF (F508del) mutation of the cystic fibrosis gene by surface plasmon resonance and biosensor technology Human Mutation 13 390 400 10338094 1:CAS:528:DyaK1MXjsFegurc%3D 10.1002/(SICI)1098-1004(1999)13:5<390::AID-HUMU8>3.0.CO;2-1 Feriotto G, Lucci M, Bianchi N, et al. Detection of the ΔF (F508del) mutation of the cystic fibrosis gene by surface plasmon resonance and biosensor technology. Human Mutation 1999; 13: 390–400
21. 21. N. Bianchi C. Rutigliano M. Passadore 1997 Targeting of the HIV-1 long terminal repeat with chromomycin potentiates the inhibitory effects of a triplex-forming oligonucleotide on Sp1-DNA interactions and in vitro transcription Biochem J 326 919 27 9307046 1:CAS:528:DyaK2sXmsVKju7k%3D Bianchi N, Rutigliano C, Passadore M, et al. Targeting of the HIV-1 long terminal repeat with chromomycin potentiates the inhibitory effects of a triplex-forming oligonucleotide on Sp1-DNA interactions and in vitro transcription. Biochem J 1997; 326: 919–27
22. 22. M. Malmqvist 1996 Epitope mapping by label-free biomolecular interaction analysis Methods 9 3 525 32 8812708 1:CAS:528:DyaK28XksVGht7s%3D 10.1006/meth.1996.0060 Malmqvist M. Epitope mapping by label-free biomolecular interaction analysis. Methods 1996; 9(3): 525–32
23. 23. K. Alfthan 1998 Surface plasmon resonance biosensors as a tool in antibody engineering Biosens Bioelectron 13 6 653 63 9828359 1:CAS:528:DyaK1cXnt1Kqtbw%3D 10.1016/S0956-5663(98)00020-7 Alfthan K. Surface plasmon resonance biosensors as a tool in antibody engineering. Biosens Bioelectron 1998; 13(6): 653–63
24. 24. I.D. Parsons B. Persson A. Mekhalfia 1995 Probing the molecular mechanism of action of co-repressor in the E. coli methionine repressor-operator complex using surface plasmon resonance (SPR) Nucleic Acids Res 23 2 211 6 7862523 1:CAS:528:DyaK2MXjvFems7k%3D 10.1093/nar/23.2.211 Parsons ID, Persson B, Mekhalfia A, et al. Probing the molecular mechanism of action of co-repressor in the E. coli methionine repressor-operator complex using surface plasmon resonance (SPR). Nucleic Acids Res 1995; 23(2): 211–6
25. 25. M. Raghavan P.J. Bjorkman 1995 BIAcore: a microchip-based system for analyzing the formation of macromolecular complexes Structure 3 4 331 3 7613863 1:CAS:528:DyaK2MXltFGjurc%3D 10.1016/S0969-2126(01)00164-2 Raghavan M, Bjorkman PJ. BIAcore: a microchip-based system for analyzing the formation of macromolecular complexes. Structure 1995; 3(4): 331–3
26. 26. M. Fivash E.M. Towler R.J. Fisher 1998 BIAcore for macromolecular interaction Curr Opin Biotechnol 9 1 97 101 9503595 1:CAS:528:DyaK1cXhs1yhsLY%3D 10.1016/S0958-1669(98)80091-8 Fivash M, Towler EM, Fisher RJ. BIAcore for macromolecular interaction. Curr Opin Biotechnol 1998; 9(1): 97–101
27. 27. M. Malmqvist 1999 BIACORE: an affinity biosensor system for characterization of biomolecular interactions Biochem Soc Trans 7 2 335 40 Malmqvist M. BIACORE: an affinity biosensor system for characterization of biomolecular interactions. Biochem Soc Trans 1999; 7(2): 335–40
28. 28. D.G. Myszka R.L. Rich 2000 Implementating surface plasmon resonance biosensors in drug discovery Pharmaceutical Sci Technol Today 9 3310 7 Myszka DG, Rich RL. Implementating surface plasmon resonance biosensors in drug discovery. Pharmaceutical Sci Technol Today 2000; 9: 3310–7
29. 29. N. J. Mol de E. Plomp M.J. Fischer 2000 Kinetic analysis of the mass transport limited interaction between the tyrosine kinase lck SH2 domain and a phosphorylated peptide studied by a new cuvette-based surface plasmon resonance instrument Anal Biochem 279 1 61 70 10683231 10.1006/abio.1999.4464 1:CAS:528:DC%2BD3cXht1SgsrY%3D de Mol NJ, Plomp E, Fischer MJ, et al. Kinetic analysis of the mass transport limited interaction between the tyrosine kinase lck SH2 domain and a phosphorylated peptide studied by a new cuvette-based surface plasmon resonance instrument. Anal Biochem 2000; 279(1): 61–70
30. 30. P.E. Buckle R.D. Davies T. Kinning 1993 The resonant mirror: a novel optical biosensor for direct sensing of biomolecular interactions part II: applications Biosensors Bioelectronics 8 365 70 10.1016/0956-5663(93)80074-Y Buckle PE, Davies RD, Kinning T, et al. The resonant mirror: a novel optical biosensor for direct sensing of biomolecular interactions part II: applications. Biosensors Bioelectronics 1993; 8: 365–70
31. 31. R. Cush J.M. Cronin W.J. Stewart 1993 The resonant mirror: a novel optical biosensor for direct sensing of biomolecular interactions part I: principle of operation and associated instrumentation Biosensors Bioelectronics 8 347 64 1:CAS:528:DyaK2cXis1CqsrY%3D 10.1016/0956-5663(93)80073-X Cush R, Cronin JM, Stewart WJ, et al. The resonant mirror: a novel optical biosensor for direct sensing of biomolecular interactions part I: principle of operation and associated instrumentation. Biosensors Bioelectronics 1993; 8: 347–64
32. 32. H.J. Watts D. Yeung H. Parkes 1995 Real-time detection and quantification of DNA hybridization by an optical biosensor Anal Chem 67 4283 9 8633773 1:CAS:528:DyaK2MXovFSkt7w%3D 10.1021/ac00119a013 Watts HJ, Yeung D, Parkes H. Real-time detection and quantification of DNA hybridization by an optical biosensor. Anal Chem 1995; 67: 4283–9
33. 33. P.A. Lowe T.J.H. Clark R.J. Davies 1998 New approaches for the analysis of molecular recognition using the IAsys evanescent wave biosensor J Mol Recognit 11 194 9 10076839 1:CAS:528:DyaK1MXhsFemsrY%3D 10.1002/(SICI)1099-1352(199812)11:1/6<194::AID-JMR422>3.0.CO;2-T Lowe PA, Clark TJH, Davies RJ, et al. New approaches for the analysis of molecular recognition using the IAsys evanescent wave biosensor. J Mol Recognit 1998; 11: 194–9
34. 34. P.R. Edwards C.H. Maule R.J. Leatherbarrow 1998 Second-order kinetic analysis of IAsys biosensor data: its use and applicability Anal Biochem 263 1 12 9750135 1:CAS:528:DyaK1cXmtlygtrc%3D 10.1006/abio.1998.2814 Edwards PR, Maule CH, Leatherbarrow RJ, et al. Second-order kinetic analysis of IAsys biosensor data: its use and applicability. Anal Biochem 1998; 263: 1–12
35. 35. D.J. Newman H. Thakkar L.P. Tang 1999 The use of optical sensors to understand cellular interactions with renal cells Ren Fail 21 349 57 10416213 1:CAS:528:DyaK1MXkvVOqsb8%3D 10.3109/08860229909085098 Newman DJ, Thakkar H, Tang LP, et al. The use of optical sensors to understand cellular interactions with renal cells. Ren Fail 1999; 21: 349–57
36. 36. V.V. Koval O.V. Gnedenko Y.D. Ivanov 1999 Real-time oligonucleotide hybridization kinetics monitored by resonant mirror technique IUMBM Life 48 317 20 1:CAS:528:DyaK1MXnt1GktL4%3D Koval VV, Gnedenko OV, Ivanov YD, et al. Real-time oligonucleotide hybridization kinetics monitored by resonant mirror technique. IUMBM Life 1999; 48: 317–20
37. 37. J. Melendez R. Carr D.U. Bartholomew 1997 Development of a surface plasmon resonance sensor for commercial applications Sensors Actuators-B 39 375 9 10.1016/S0925-4005(97)80237-7 Melendez J, Carr R, Bartholomew DU, et al. Development of a surface plasmon resonance sensor for commercial applications. Sensors Actuators-B 1997; 39: 375–9
38. 38. J.L. Elkind D.I. Stimpson A. Anita 1999 Integrated analytical sensors: the use of the TISPR-1 as a biosensor Sensors and Actuators-B 54 182 90 10.1016/S0925-4005(98)00336-0 Elkind JL, Stimpson DI, Anita A, et al. Integrated analytical sensors: the use of the TISPR-1 as a biosensor. Sensors and Actuators-B 1999; 54: 182–90
39. 39. R.G. Woodbury C. Wendin J. Clendenning 1998 Construction of surface plasmon resonance biosensors using a gold-binding polypeptide and a miniature integrated sensor Biosensors Bioelectronics 13 1117 26 9842707 1:CAS:528:DyaK1cXnsFSktLk%3D 10.1016/S0956-5663(98)00060-8 Woodbury RG, Wendin C, Clendenning J, et al. Construction of surface plasmon resonance biosensors using a gold-binding polypeptide and a miniature integrated sensor. Biosensors Bioelectronics 1998; 13: 1117–26
40. 40. K. Senzaki M. Ogawa T. Yagi 1999 Proteins of the CNR family are Multiple receptors for reelin Cell 99 635 47 10612399 1:CAS:528:DC%2BD3cXitVKl 10.1016/S0092-8674(00)81552-4 Senzaki K, Ogawa M, Yagi T. Proteins of the CNR family are Multiple receptors for reelin. Cell 1999; 99: 635–47
41. 41. M. Hosono K. Ishikawam R. Mineki 1999 Tandem repeat structure of rhamnose-binding lectin from catfish (Silurus asotus) eggs Biochim Biophys Acta 1472 668 65 10564781 1:CAS:528:DyaK1MXntlClt7g%3D 10.1016/S0304-4165(99)00185-3 Hosono M, Ishikawam K, Mineki R, et al. Tandem repeat structure of rhamnose-binding lectin from catfish (Silurus asotus) eggs. Biochim Biophys Acta 1999; 1472: 668–65
42. 42. R. Karlsson R. Stahlberg 1995 Surface plasmon resonance detection and multispot sensing for direct monitoring of interactions involving low-molecular-weight analytes and for determination of low affinities Anal Biochem 228 274 80 8572306 1:CAS:528:DyaK2MXntFWru70%3D 10.1006/abio.1995.1350 Karlsson R, Stahlberg R. Surface plasmon resonance detection and multispot sensing for direct monitoring of interactions involving low-molecular-weight analytes and for determination of low affinities. Anal Biochem 1995; 228: 274–80
43. 43. B. Goldstein D. Coombs X. He 1999 The influence of transport on the kinetics of binding to surface receptors: application to cells and BIAcore J Mol Recognit 12 5 293 9 10556877 1:CAS:528:DyaK1MXnvVans7s%3D 10.1002/(SICI)1099-1352(199909/10)12:5<293::AID-JMR472>3.0.CO;2-M Goldstein B, Coombs D, He X, et al. The influence of transport on the kinetics of binding to surface receptors: application to cells and BIAcore. J Mol Recognit 1999; 12(5): 293–9
44. 44. R. Karlsson 1999 Affinity analysis of non-steady-state data obtained under mass transport limited conditions using BIAcore technology J Mol Recognit 12 5 285 92 10556876 1:CAS:528:DyaK1MXnvVans7o%3D 10.1002/(SICI)1099-1352(199909/10)12:5<285::AID-JMR469>3.0.CO;2-Y Karlsson R. Affinity analysis of non-steady-state data obtained under mass transport limited conditions using BIAcore technology. J Mol Recognit 1999; 12(5): 285–92
45. 45. R.J. Ober E.S. Ward 1999 The influence of signal noise on the accuracy of kinetic constants measured by surface plasmon resonance experiments Anal Biochem 273 1 49 59 10452798 1:CAS:528:DyaK1MXlt1WktLc%3D 10.1006/abio.1999.4185 Ober RJ, Ward ES. The influence of signal noise on the accuracy of kinetic constants measured by surface plasmon resonance experiments. Anal Biochem 1999; 273(1): 49–59
46. 46. R.J. Ober E.S. Ward 1999 The choice of reference cell in the analysis of kinetic data using BIAcore Anal Biochem 271 1 70 80 10361006 1:CAS:528:DyaK1MXjsFKnsrY%3D 10.1006/abio.1999.4129 Ober RJ, Ward ES. The choice of reference cell in the analysis of kinetic data using BIAcore. Anal Biochem 1999; 271(1): 70–80
47. 47. L. Joss T.A. Morton M.L. Doyle 1998 Interpreting kinetic rate constants from optical biosensor data recorded on a decaying surface Anal Biochem 261 2 203 10 9716423 1:CAS:528:DyaK1cXlslKhsbw%3D 10.1006/abio.1998.2744 Joss L, Morton TA, Doyle ML, et al. Interpreting kinetic rate constants from optical biosensor data recorded on a decaying surface. Anal Biochem 1998; 261(2): 203–10
48. 48. A.A. Kortt G.W. Oddie P. Iliades 1997 Nonspecific amine immobilization of ligand can be a potential source of error in BIAcore binding experiments and may reduce binding affinities Anal Biochem 253 1 103 11 9356148 1:CAS:528:DyaK2sXnsVegtrY%3D 10.1006/abio.1997.2333 Kortt AA, Oddie GW, Iliades P, et al. Nonspecific amine immobilization of ligand can be a potential source of error in BIAcore binding experiments and may reduce binding affinities. Anal Biochem 1997; 253(1): 103–11
49. 49. T.C. Cott Van L.D. Loomis R.R. Redfield 1992 Real-time biospecific interaction analysis of antibody reactivity to peptides from the envelope glycoprotein, gp160, of HIV-1 J Immunol Methods 146 2 163 76 10.1016/0022-1759(92)90225-I VanCott TC, Loomis LD, Redfield RR, et al. Real-time biospecific interaction analysis of antibody reactivity to peptides from the envelope glycoprotein, gp160, of HIV-1. J Immunol Methods 1992; 146(2): 163–76
50. 50. D. Altschuh M.C. Dubs E. Weiss 1992 Determination of kinetic constants for the interaction between a monoclonal antibody and peptides using surface plasmon resonance Biochemistry 31 27 6298 304 1627568 1:CAS:528:DyaK38XksVKhsbo%3D 10.1021/bi00142a019 Altschuh D, Dubs MC, Weiss E, et al. Determination of kinetic constants for the interaction between a monoclonal antibody and peptides using surface plasmon resonance. Biochemistry 1992; 31(27): 6298–304
51. 51. J.C. Mani V. Marchi C. Cucurou 1994 Effect of HIV-1 peptide presentation on the affinity constants of two monoclonal antibodies determined by BIAcore technology Mol Immunol 31 6 439 44 7514268 1:CAS:528:DyaK2cXjt1Sru78%3D 10.1016/0161-5890(94)90063-9 Mani JC, Marchi V, Cucurou C. Effect of HIV-1 peptide presentation on the affinity constants of two monoclonal antibodies determined by BIAcore technology. Mol Immunol 1994; 31(6): 439–44
52. 52. R.M. Wohlhueter K. Parekh V. Udhayakumar 1994 Analysis of binding of monoclonal antibody to a malarial peptide by surface plasmon resonance biosensor and integrated rate equations J Immunol 153 1 181 9 8207235 1:CAS:528:DyaK2cXltVKis7c%3D Wohlhueter RM, Parekh K, Udhayakumar V, et al. Analysis of binding of monoclonal antibody to a malarial peptide by surface plasmon resonance biosensor and integrated rate equations. J Immunol 1994; 153(1): 181–9
53. 53. L.J. Hefta M. Neumaier J.E. Shively 1998 Kinetic and affinity constants of epitope specific anti-carcinoembryonic antigen (CEA) monoclonal antibodies for CEA and engineered CEA domain constructs Immunotechnology 4 1 49 57 9661814 1:CAS:528:DyaK1cXks1Khsr8%3D 10.1016/S1380-2933(98)00004-9 Hefta LJ, Neumaier M, Shively JE. Kinetic and affinity constants of epitope specific anti-carcinoembryonic antigen (CEA) monoclonal antibodies for CEA and engineered CEA domain constructs. Immunotechnology 1998; 4(1): 49–57
54. 54. D.A. Dougan R.L. Malby L.C. Gruen 1998 Effects of substitutions in the binding surface of an antibody on antigen affinity Protein Eng 11 1 65 74 9579662 1:CAS:528:DyaK1cXisFWqsL0%3D 10.1093/protein/11.1.65 Dougan DA, Malby RL, Gruen LC, et al. Effects of substitutions in the binding surface of an antibody on antigen affinity. Protein Eng 1998; 11(1): 65–74
55. 55. J. Osborne P. Harrison R. Butcher 1999 Novel super-high affinity sheep monoclonal antibodies against CEA bind colon and lung adenocarcinoma Hybridoma 18 2 183 91 10380018 1:CAS:528:DyaK1MXjvFKisLY%3D 10.1089/hyb.1999.18.183 Osborne J, Harrison P, Butcher R, et al. Novel super-high affinity sheep monoclonal antibodies against CEA bind colon and lung adenocarcinoma. Hybridoma 1999; 18(2): 183–91
56. 56. R. Mobini M. Fu G. Wallukat 2000 A monoclonal antibody directed against an autoimmune epitope on the human beta1-adrenergic receptor recognized in idiopathic dilated cardiomyopathy Hybridoma 19 2 135 42 10868793 1:CAS:528:DC%2BD3cXksFSrs7c%3D 10.1089/02724570050031176 Mobini R, Fu M, Wallukat G, et al. A monoclonal antibody directed against an autoimmune epitope on the human beta1-adrenergic receptor recognized in idiopathic dilated cardiomyopathy. Hybridoma 2000; 19(2): 135–42
57. 57. B. Johne 1998 Epitope mapping by surface plasmon resonance in the BIAcore Mol Biotechnol 9 1 65 71 9592769 1:CAS:528:DyaK1cXjtV2ku70%3D 10.1007/BF02752698 Johne B. Epitope mapping by surface plasmon resonance in the BIAcore. Mol Biotechnol 1998; 9(1): 65–71
58. 58. R.J. Fisher A. Rein M. Fivash 1998 Sequence-specific binding of human immunodeficiency virus type 1 nucleocapsid protein to short oligonucleotides J Virol 72 3 1902 9 9499042 1:CAS:528:DyaK1cXhtFehsLY%3D Fisher RJ, Rein A, Fivash M, et al. Sequence-specific binding of human immunodeficiency virus type 1 nucleocapsid protein to short oligonucleotides. J Virol 1998; 72(3): 1902–9
59. 59. M. Malmqvist 1996 Epitope mapping by label-free biomolecular interaction analysis Methods 9 3 525 32 8812708 1:CAS:528:DyaK28XksVGht7s%3D 10.1006/meth.1996.0060 Malmqvist M. Epitope mapping by label-free biomolecular interaction analysis. Methods 1996; 9(3): 525–32
60. 60. B. Johne M. Gadnell K. Hansen 1993 Epitope mapping and binding kinetics of monoclonal antibodies studied by real time biospecific interaction analysis using surface plasmon resonance J Immunol Methods 160 2 191 8 7681459 1:CAS:528:DyaK3sXktVCgsLk%3D 10.1016/0022-1759(93)90177-9 Johne B, Gadnell M, Hansen K. Epitope mapping and binding kinetics of monoclonal antibodies studied by real time biospecific interaction analysis using surface plasmon resonance. J Immunol Methods 1993; 160(2): 191–8
61. 61. L. Bellanger C. Andres P. Seguin 1999 Epitope mapping of 53 antibodies against prostate-specific antigen Tumour Biol 20 18 23 10628404 1:CAS:528:DyaK1MXotFWrur8%3D 10.1159/000056525 Bellanger L, Andres C, Seguin P. Epitope mapping of 53 antibodies against prostate-specific antigen. Tumour Biol 1999; 20: 18–23
62. 62. Y.M. Geld Van Der P.C. Limburg C.G. Kallenberg 1999 Characterization of monoclonal antibodies to proteinase 3 (PR3) as candidate tools for epitope mapping of human anti-PR3 autoantibodies Clin Exp Immunol 118 3 487 96 10.1046/j.1365-2249.1999.01079.x Van Der Geld YM, Limburg PC, Kallenberg CG. Characterization of monoclonal antibodies to proteinase 3 (PR3) as candidate tools for epitope mapping of human anti-PR3 autoantibodies. Clin Exp Immunol 1999; 118(3): 487–96
63. 63. J. Zhang R. Kuvelkar N.J. Murgolo 1999 Mapping and characterization of the epitope(s) of Sch 55700, a humanized mAb, that inhibits human IL-5 Int Immunol 11 12 1935 44 10590259 1:CAS:528:DC%2BD3cXktFWgtg%3D%3D 10.1093/intimm/11.12.1935 Zhang J, Kuvelkar R, Murgolo NJ, et al. Mapping and characterization of the epitope(s) of Sch 55700, a humanized mAb, that inhibits human IL-5. Int Immunol 1999; 11(12): 1935–44
64. 64. B. Karim R. Beliard J.J. Huart 1994 Four epitopes on tumor necrosis factor-alpha defined by murine anti-tumor necrosis factor-alpha monoclonal antibodies Immunol Lett 41 139 45 8002029 1:CAS:528:DyaK2cXmt1ygtb0%3D 10.1016/0165-2478(94)90124-4 Karim B, Beliard R, Huart JJ, et al. Four epitopes on tumor necrosis factor-alpha defined by murine anti-tumor necrosis factor-alpha monoclonal antibodies. Immunol Lett 1994; 41: 139–45
65. 65. T. Stigbrand C. Andres L. Bellanger 1998 Epitope specificity of 30 monoclonal antibodies against cytokeratin antigens: the ISOBM TD5-1 Workshop Tumour Biol 19 132 152 9486565 1:CAS:528:DyaK1cXjt1Ortb0%3D 10.1159/000029984 Stigbrand T, Andres C, Bellanger L, et al. Epitope specificity of 30 monoclonal antibodies against cytokeratin antigens: the ISOBM TD5-1 Workshop. Tumour Biol1998; 19: 132–152
66. 66. P. Bjorquist J. Ehnebom T. Inghardt 1997 Epitopes on plasminogen activator inhibitor type-1 important for binding to tissue plasminogen activator Biochim Biophys Acta 1341 1 87 98 9300812 1:STN:280:DyaK2svksVarsg%3D%3D 10.1016/S0167-4838(97)00065-4 Bjorquist P, Ehnebom J, Inghardt T, et al. Epitopes on plasminogen activator inhibitor type-1 important for binding to tissue plasminogen activator. Biochim Biophys Acta 1997; 1341(1): 87–98
67. 67. A. Ota S. Ueda 1998 Evaluation of the affinity measurement of anti-HIV-1 p17 monoclonal antibody by BIAcore Hybridoma 17 471 7 9873993 1:CAS:528:DyaK1MXitVCntg%3D%3D 10.1089/hyb.1998.17.471 Ota A, Ueda S. Evaluation of the affinity measurement of anti-HIV-1 p17 monoclonal antibody by BIAcore. Hybridoma 1998; 17: 471–7
68. 68. M.B. Khalifa M. Weidenhaupt L. Choulier 2000 Effects on interaction kinetics of mutations at the VH-VL interface of Fabs depend on the structural context J Mol Recognit 13 3 127 39 10867708 1:STN:280:DC%2BD3cvhslehsQ%3D%3D 10.1002/1099-1352(200005/06)13:3<127::AID-JMR495>3.0.CO;2-9 Khalifa MB, Weidenhaupt M, Choulier L, et al. Effects on interaction kinetics of mutations at the VH-VL interface of Fabs depend on the structural context. J Mol Recognit 2000; 13(3): 127–39
69. 69. U. Stenman E. Paus W.J. Allard 1999 Summary report of the TD-3 workshop: characterization of 83 antibodies against prostate-specific antigen Tumour Biol 20 1 12 10628402 1:CAS:528:DyaK1MXotFWrtbc%3D 10.1159/000056523 Stenman U, Paus E, Allard WJ, et al. Summary report of the TD-3 workshop: characterization of 83 antibodies against prostate-specific antigen. Tumour Biol 1999; 20: 1–12
70. 70. J. Liautard J.P. Gaillard J.C. Mani 1994 Epitope analysis of human IL-6 receptor gp80 molecule with monoclonal antibodies Eur Cytokine Netw 5 3 293 300 7524715 1:CAS:528:DyaK2cXmtVaru7g%3D Liautard J, Gaillard JP, Mani JC, et al. Epitope analysis of human IL-6 receptor gp80 molecule with monoclonal antibodies. Eur Cytokine Netw 1994; 5(3): 293–300
71. 71. B. Robert M. Dorvillius F. Buchegger 1999 Tumor targeting with newly designed biparatopic antibodies directed against two different epitopes of the carcinoembryonic antigen (CEA) Int J Cancer 81 2 285 91 10188732 1:CAS:528:DyaK1MXisVSlt7w%3D 10.1002/(SICI)1097-0215(19990412)81:2<285::AID-IJC19>3.0.CO;2-T Robert B, Dorvillius M, Buchegger F, et al. Tumor targeting with newly designed biparatopic antibodies directed against two different epitopes of the carcinoembryonic antigen (CEA). Int J Cancer 1999; 81(2): 285–91
72. 72. J.E. Thompson T.J. Vaughan A.J. Williams 1999 A fully human antibody neutralising biologically active human TGFbeta2 for use in therapy J Immunol Methods 227 17 29 10485251 1:CAS:528:DyaK1MXkvVCjtL4%3D 10.1016/S0022-1759(99)00060-5 Thompson JE, Vaughan TJ, Williams AJ, et al. A fully human antibody neutralising biologically active human TGFbeta2 for use in therapy. J Immunol Methods 1999; 227: 17–29
73. 73. D.W. Coomber N.J. Hawkins M.A. Clark 1999 Generation of anti-p53 Fab fragments from individuals with colorectal cancer using phage display J Immunol 163 4 2276 83 10438972 1:CAS:528:DyaK1MXltFagtrs%3D Coomber DW, Hawkins NJ, Clark MA, et al. Generation of anti-p53 Fab fragments from individuals with colorectal cancer using phage display. J Immunol 1999; 163(4): 2276–83
74. 74. T.L. Vassilev M.D. Kazatchkine J.P. Huyen Van 1999 Inhibition of cell adhesion by antibodies to Arg-Gly-Asp (RGD) in normal immunoglobulin for therapeutic use (intravenous immunoglobulin, IVIg) Blood 93 11 3624 31 10339467 1:CAS:528:DyaK1MXjsVOnsL4%3D Vassilev TL, Kazatchkine MD, Van Huyen JP, et al. Inhibition of cell adhesion by antibodies to Arg-Gly-Asp (RGD) in normal immunoglobulin for therapeutic use (intravenous immunoglobulin, IVIg). Blood 1999; 93(11): 3624–31
75. 75. S. Allauzen J.C. Mani C. Granier 1995 Epitope mapping and binding analysis of insulin-specific monoclonal antibodies using a biosensor approach J Immunol Methods 183 1 27 32 7541430 1:CAS:528:DyaK2MXmtVykurs%3D 10.1016/0022-1759(95)00020-B Allauzen S, Mani JC, Granier C, et al. Epitope mapping and binding analysis of insulin-specific monoclonal antibodies using a biosensor approach. J Immunol Methods 1995; 183(1): 27–32
76. 76. S. Manes L. Kremer J.P. Albar 1997 Functional epitope mapping of insulin-like growth factor I (IGF-I) by anti-IGF-I monoclonal antibodies Endocrinology 138 3 905 15 9048589 1:CAS:528:DyaK2sXht1Oks7c%3D 10.1210/en.138.3.905 Manes S, Kremer L, Albar JP, et al. Functional epitope mapping of insulin-like growth factor I (IGF-I) by anti-IGF-I monoclonal antibodies. Endocrinology 1997; 138(3): 905–15
77. 77. M. Brigham-Burke J.R. Edwards D.J. O’shannessy 1992 Detection of receptor-ligand interactions using surface plasmon resonance: model studies employing the HIV-1 gp120/CD4 interaction Anal Biochem 205 1 125 31 1443549 1:CAS:528:DyaK38XlsVKmsbc%3D 10.1016/0003-2697(92)90588-X Brigham-Burke M, Edwards JR, O’shannessy DJ. Detection of receptor-ligand interactions using surface plasmon resonance: model studies employing the HIV-1 gp120/CD4 interaction. Anal Biochem 1992; 205(1): 125–31
78. 78. A.G. Batzer D. Rotin J.M. Urena 1994 Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor Mol Cell Biol 14 8 5192 201 7518560 1:CAS:528:DyaK2cXlt1Gnur8%3D Batzer AG, Rotin D, Urena JM, et al. Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor. Mol Cell Biol 1994; 14(8): 5192–201
79. 79. O. Shliom M. Huang B. Sachais 2000 Novel interactions between urokinase and its receptor J Biol Chem 275 32 24304 12 10801829 1:CAS:528:DC%2BD3cXlslyquro%3D 10.1074/jbc.M002024200 Shliom O, Huang M, Sachais B, et al. Novel interactions between urokinase and its receptor. J Biol Chem 2000; 275(32): 24304–12
80. 80. C. G. De S. Grothe R. Lortie 2000 Real-time kinetic studies on the interaction of transforming growth factor alpha with the epidermal growth factor receptor extracellular domain reveal a conformational change model Biochemistry 39 31 9466 76 10.1021/bi992987r 1:CAS:528:DC%2BD3cXksleitr8%3D De Crescenzo G, Grothe S, Lortie R, et al. Real-time kinetic studies on the interaction of transforming growth factor alpha with the epidermal growth factor receptor extracellular domain reveal a conformational change model. Biochemistry 2000; 39(31): 9466–76
81. 81. C. Poiesi A. Albertini S. Ghielmi 1993 Kinetic analysis of TNF-alpha oligomermonomer transition by surface plasmon resonance and immunochemical methods Cytokine 5 6 539 45 8186365 1:CAS:528:DyaK2cXisVaitL8%3D 10.1016/S1043-4666(05)80002-X Poiesi C, Albertini A, Ghielmi S, et al. Kinetic analysis of TNF-alpha oligomermonomer transition by surface plasmon resonance and immunochemical methods. Cytokine 1993; 5(6): 539–45
82. 82. H.R. Lijnen C. F. De D. Collen 1994 Characterization of the binding of urokinase-type plasminogen activator (u-PA) to plasminogen, to plasminogen-activator inhibitor-1 and to the u-PA receptor Eur J Biochem 224 2 567 74 7925373 1:CAS:528:DyaK2cXlsleksLs%3D 10.1111/j.1432-1033.1994.00567.x Lijnen HR, De Cock F, Collen D. Characterization of the binding of urokinase-type plasminogen activator (u-PA) to plasminogen, to plasminogen-activator inhibitor-1 and to the u-PA receptor. Eur J Biochem 1994; 224(2): 567–74
83. 83. H.R. Lijnen F. Cock De B. Hoef Van 1994 Characterization of the interaction between plasminogen and staphylokinase Eur J Biochem 224 1 143 9 8076635 1:CAS:528:DyaK2cXlsFWqu7k%3D 10.1111/j.1432-1033.1994.tb20005.x Lijnen HR, DeCock F, Van Hoef B, et al. Characterization of the interaction between plasminogen and staphylokinase. Eur J Biochem 1994; 224(1): 143–9
84. 84. A.G. Batzer D. Rotin J.M. Urena 1994 Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor Mol Cell Biol 14 8 5192 201 7518560 1:CAS:528:DyaK2cXlt1Gnur8%3D Batzer AG, Rotin D, Urena JM, et al. Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor. Mol Cell Biol 1994; 14(8): 5192–201
85. 85. M. Jansson M. Uhlen B. Nilsson 1997 Structural changes in insulin-like growth factor (IGF) I mutant proteins affecting binding kinetic rates to IGF binding protein 1 and IGF-I receptor Biochemistry 36 14 4108 17 9100004 1:CAS:528:DyaK2sXitFSrs7o%3D 10.1021/bi961553i Jansson M, Uhlen M, Nilsson B. Structural changes in insulin-like growth factor (IGF) I mutant proteins affecting binding kinetic rates to IGF binding protein 1 and IGF-I receptor. Biochemistry 1997; 36(14): 4108–17
86. 86. A. Al-Shamkhani S. Mallett M.H. Brown 1997 Affinity and kinetics of the interaction between soluble trimeric OX40 ligand, a member of the tumor necrosis factor superfamily, and its receptor OX40 on activated T cells J Biol Chem 272 8 5275 82 9030600 1:CAS:528:DyaK2sXhsVaks7w%3D 10.1074/jbc.272.8.5275 Al-Shamkhani A, Mallett S, Brown MH, et al. Affinity and kinetics of the interaction between soluble trimeric OX40 ligand, a member of the tumor necrosis factor superfamily, and its receptor OX40 on activated T cells. J Biol Chem 1997; 272(8): 5275–82
87. 87. S.F. Liparoto T.L. Ciardelli 1999 Biosensor analysis of the interleukin-2 receptor complex J Mol Recognit 12 5 316 21 10556880 1:CAS:528:DyaK1MXnvVans7Y%3D 10.1002/(SICI)1099-1352(199909/10)12:5<316::AID-JMR468>3.0.CO;2-1 Liparoto SF, Ciardelli TL. Biosensor analysis of the interleukin-2 receptor complex. J Mol Recognit 1999; 12(5): 316–21
88. 88. R. Karlsson M. Kullman-Magnusson M.D. Hamalainen 2000 Biosensor analysis of drug-target interactions: direct and competitive binding assays for investigation of interactions between thrombin and thrombin inhibitors Anal Biochem 278 1 1 13 10640347 1:CAS:528:DC%2BD3cXksl2msA%3D%3D 10.1006/abio.1999.4406 Karlsson R, Kullman-Magnusson M, Hamalainen MD, et al. Biosensor analysis of drug-target interactions: direct and competitive binding assays for investigation of interactions between thrombin and thrombin inhibitors. Anal Biochem 2000; 278(1): 1–13
89. 89. Z. Wu K.W. Johnson Y. Choi 1995 Ligand binding analysis of soluble interleukin-2 receptor complexes by surface plasmon resonance J Biol Chem 270 27 16045 51 7608166 1:CAS:528:DyaK2MXmvVGns7o%3D 10.1074/jbc.270.27.16045 Wu Z, Johnson KW, Choi Y, et al. Ligand binding analysis of soluble interleukin-2 receptor complexes by surface plasmon resonance. J Biol Chem 1995; 270(27): 16045–51
90. 90. B.W. Park H.T. Zhang C. Wu 2000 Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo Nat Biotechnol 18 2 194 8 10657127 1:CAS:528:DC%2BD3cXhtVOltrY%3D 10.1038/72651 Park BW, Zhang HT, Wu C, et al. Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo. Nat Biotechnol 2000; 18(2): 194–8
91. 91. D.G. Myszka P.R. Arulanantham T. Sana 1996 Kinetic analysis of ligand binding to interleukin-2 receptor complexes created on an optical biosensor surface Protein Sci 5 12 2468 78 8976555 1:CAS:528:DyaK2sXis1Km 10.1002/pro.5560051209 Myszka DG, Arulanantham PR, Sana T, et al. Kinetic analysis of ligand binding to interleukin-2 receptor complexes created on an optical biosensor surface. Protein Sci 1996; 5(12): 2468–78
92. 92. A. Sadana 1998 Analyte-receptor binding kinetics for biosensor applications. An analysis of the influence of the fractal dimension on the binding rate coefficient Appl Biochem Biotechnol 73 89 112 9779572 1:CAS:528:DyaK1cXms1Ghsrg%3D 10.1007/BF02785648 Sadana A. Analyte-receptor binding kinetics for biosensor applications. An analysis of the influence of the fractal dimension on the binding rate coefficient. Appl Biochem Biotechnol 1998; 73: 89–112
93. 93. P.O. Markgren M. Hamalainen U.H. Danielson 2000 Kinetic analysis of the interaction between HIV-1 protease and inhibitors using optical biosensor technology Anal Biochem 279 1 71 8 10683232 1:CAS:528:DC%2BD3cXht1Sgs74%3D 10.1006/abio.1999.4467 Markgren PO, Hamalainen M, Danielson UH. Kinetic analysis of the interaction between HIV-1 protease and inhibitors using optical biosensor technology. Anal Biochem 2000; 279(1): 71–8
94. 94. E. Takano M. Hatanaka M. Maki 1994 Real-time-analysis of the calcium-dependent interaction between calmodulin and a synthetic oligopeptide of calcineurin by a surface plasmon resonance biosensor FEBS Lett 352 2 247 50 7925982 1:CAS:528:DyaK2cXmslCktb4%3D 10.1016/0014-5793(94)00965-1 Takano E, Hatanaka M, Maki M. Real-time-analysis of the calcium-dependent interaction between calmodulin and a synthetic oligopeptide of calcineurin by a surface plasmon resonance biosensor. FEBS Lett 1994; 352(2): 247–50
95. 95. H.M. Shepard G.D. Lewis J.C. Sarup 1991 Monoclonal antibody therapy of human cancer: taking the HER2 protooncogene to the clinic J Clin Immunol 11 3 117 27 1679763 1:CAS:528:DyaK3MXmsFent7w%3D 10.1007/BF00918679 Shepard HM, Lewis GD, Sarup JC, et al. Monoclonal antibody therapy of human cancer: taking the HER2 protooncogene to the clinic. J Clin Immunol 1991; 11(3): 117–27
96. 96. O.G. Berg P.H. Hippel Von 1988 Selection of DNA binding sites by regulatory proteins Trends Biochem Sci 13 207 11 3079537 1:CAS:528:DyaL1cXlt1Cnt7o%3D 10.1016/0968-0004(88)90085-0 Berg OG, VonHippel PH. Selection of DNA binding sites by regulatory proteins. Trends Biochem Sci 1988; 13: 207–11
97. 97. S. Faisst S. Meyer 1992 Compilation of vertebrate-encoded transcription factors Nucleic Acids Res 20 3 26 1738600 1:CAS:528:DyaK38XhtVShs7w%3D 10.1093/nar/20.1.3 Faisst S, Meyer S. Compilation of vertebrate-encoded transcription factors. Nucleic Acids Res 1992; 20: 3–26
98. 98. P.J. Mitchell R. Tjian 1989 Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins Science 2 371 8 10.1126/science.2667136 Mitchell PJ, Tjian R. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 1989; 2: 371–8
99. 99. L. Weis D. Reinberg 1992 Transcription by RNA polymerase II: initiator-directed formation of transcription-competent complexes FASEB J 6 3300 9 1426767 1:CAS:528:DyaK3sXjtlKitw%3D%3D Weis L, Reinberg D. Transcription by RNA polymerase II: initiator-directed formation of transcription-competent complexes. FASEB J 1992; 6: 3300–9
100. 100. R.J. Fisher M. Fivash J. Casas-Finet 1994 Real-time DNA binding measurements of the ETS1 recombinant oncoproteins reveal significant kinetic differences between the p42 and p51 isoforms Protein Sci 3 2 257 66 8003962 1:CAS:528:DyaK2MXjslWh 10.1002/pro.5560030210 Fisher RJ, Fivash M, Casas-Finet J, et al. Real-time DNA binding measurements of the ETS1 recombinant oncoproteins reveal significant kinetic differences between the p42 and p51 isoforms. Protein Sci 1994; 3(2): 257–66
101. 101. H. Terenzi I. Petropoulos C. Ellouze 1995 Interaction of DNA binding domain of HNF-3 alpha with its transferrin enhancer DNA specific target site FEBS Lett 369 2-3 277 82 7649272 1:CAS:528:DyaK2MXnslyhsL0%3D 10.1016/0014-5793(95)00767-4 Terenzi H, Petropoulos I, Ellouze C, et al. Interaction of DNA binding domain of HNF-3 alpha with its transferrin enhancer DNA specific target site. FEBS Lett 1995; 369(2-3): 277–82
102. 102. A.C. Malmborg K. Johansson M. Sigvardsson 1995 Real-time analysis of Oct protein-octamer interaction and transcription complex assembly Mol Immunol 32 1429 42 8643112 1:CAS:528:DyaK28Xhs1ahsro%3D 10.1016/0161-5890(95)00067-4 Malmborg AC, Johansson K, Sigvardsson M, et al. Real-time analysis of Oct protein-octamer interaction and transcription complex assembly. Mol Immunol 1995; 32: 1429–42
103. 103. K. Paal P.A. Baeuerle M.L. Schmitz 1997 Basal transcription factors TBP and TFIIB and the viral coactivator E1A 13S bind with distinct affinities and kinetics to the transactivation domain of NF-kappaB p65 Nucleic Acids Res 25 5 1050 5 9023117 1:CAS:528:DyaK2sXhvVans7w%3D 10.1093/nar/25.5.1050 Paal K, Baeuerle PA, Schmitz ML. Basal transcription factors TBP and TFIIB and the viral coactivator E1A 13S bind with distinct affinities and kinetics to the transactivation domain of NF-kappaB p65. Nucleic Acids Res 1997; 25(5): 1050–5
104. 104. R. Gambari N. Bianchi C. Rutigliano 1997 Surface plasmon resonance for real-time detection of molecular interactions between chromomycin and target DNA sequences Int J Oncol 11 145 9 21528193 1:CAS:528:DyaK2sXksVGhsbo%3D Gambari R, Bianchi N, Rutigliano C, et al. Surface plasmon resonance for real-time detection of molecular interactions between chromomycin and target DNA sequences. Int J Oncol 1997; 11: 145–9
105. 105. B.J. Cheskis S. Karathanasis C.R. Lyttle 1997 Estrogen receptor ligands modulate its interaction with DNA J Biol Chem 272 17 11384 91 9111047 1:CAS:528:DyaK2sXjtVamurg%3D 10.1074/jbc.272.17.11384 Cheskis BJ, Karathanasis S, Lyttle CR. Estrogen receptor ligands modulate its interaction with DNA. J Biol Chem 1997; 272(17): 11384–91
106. 106. J. Aramburu F. Garcia-Cozar A. Raghavan 1998 Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT Mol Cell 1 5 627 37 9660947 1:CAS:528:DyaK1cXivFyqur8%3D 10.1016/S1097-2765(00)80063-5 Aramburu J, Garcia-Cozar F, Raghavan A, et al. Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT. Mol Cell 1998; 1(5): 627–37
107. 107. F. Cornille P. Emery W. Schuler 1998 Protein, Nucleotide, Structure DNA binding properties of a chemically synthesized DNA binding domain of hRFX1 Nucleic Acids Res 26 2143 9 9547272 1:CAS:528:DyaK1cXjtFymu7g%3D 10.1093/nar/26.9.2143 Cornille F, Emery P, Schuler W, et al. Protein, Nucleotide, Structure DNA binding properties of a chemically synthesized DNA binding domain of hRFX1. Nucleic Acids Res 1998; 26: 2143–9
108. 108. D. Bryan S.J. Aylwin D.J. Newman 1999 Steroidogenic factor 1-DNA binding: a kinetic analysis using surface plasmon resonance J Mol Endocrinol 22 3 241 9 10343283 1:CAS:528:DyaK1MXktVChu7k%3D 10.1677/jme.0.0220241 Bryan D, Aylwin SJ, Newman DJ, et al. Steroidogenic factor 1-DNA binding: a kinetic analysis using surface plasmon resonance. J Mol Endocrinol 1999; 22(3): 241–9
109. 109. Y. Azuma L. Renault J.A. Garcia-Ranea 1999 A. model of the ran-RCC1 interaction using biochemical and docking experiments J Mol Biol 289 4 1119 30 10369786 1:CAS:528:DyaK1MXjslKht7w%3D 10.1006/jmbi.1999.2820 Azuma Y, Renault L, Garcia-Ranea JA, et al. A. model of the ran-RCC1 interaction using biochemical and docking experiments. J Mol Biol 1999; 289(4): 1119–30
110. 110. M. Oda K. Furukawa A. Sarai 1999 Kinetic analysis of DNA binding by the c-Myb DNA-binding domain using surface plasmon resonance FEBS Lett 454 3 288 92 10431824 1:CAS:528:DyaK1MXks1Olsr8%3D 10.1016/S0014-5793(99)00833-9 Oda M, Furukawa K, Sarai A, et al. Kinetic analysis of DNA binding by the c-Myb DNA-binding domain using surface plasmon resonance. FEBS Lett 1999; 454(3): 288–92
111. 111. F. Pio N. Assa-Munt J. Yguerabide 1999 Mutants of ETS domain PU.1 and GGAA/T recognition: free energies and kinetics Protein Sci 8 10 2098 109 10548056 1:CAS:528:DyaK1MXntV2lsbo%3D 10.1110/ps.8.10.2098 Pio F, Assa-Munt N, Yguerabide J, et al. Mutants of ETS domain PU.1 and GGAA/T recognition: free energies and kinetics. Protein Sci 1999; 8(10): 2098–109
112. 112. L. Galio S. Briquet S. Cot 1997 Analysis of interactions between huGATA-3 transcription factor and three GATA regulatory elements of HIV-1 long terminal repeat, by surface plasmon resonance Anal Biochem 253 1 70 7 9356144 1:CAS:528:DyaK2sXnsVegtro%3D 10.1006/abio.1997.2367 Galio L, Briquet S, Cot S, et al. Analysis of interactions between huGATA-3 transcription factor and three GATA regulatory elements of HIV-1 long terminal repeat, by surface plasmon resonance. Anal Biochem 1997; 253(1): 70–7
113. 113. I. Michalopoulos R.T. Hay 1999 Role of the conserved lysine 80 in stabilisation of NF-kappaB p50 DNA binding Nucleic Acids Res 27 2 503 9 9862972 1:CAS:528:DyaK1MXhtVKmsbg%3D 10.1093/nar/27.2.503 Michalopoulos I, Hay RT. Role of the conserved lysine 80 in stabilisation of NF-kappaB p50 DNA binding. Nucleic Acids Res 1999; 27(2): 503–9
114. 114. E.T. Young N. Kacherovsky C. Cheng 2000 An accessory DNA binding motif in the zinc finger protein Adr1 assists stable binding to DNA and can be replaced by a third finger Biochemistry 39 3 567 74 10642181 1:CAS:528:DyaK1MXnvF2qu7g%3D 10.1021/bi992049r Young ET, Kacherovsky N, Cheng C. An accessory DNA binding motif in the zinc finger protein Adr1 assists stable binding to DNA and can be replaced by a third finger. Biochemistry 2000; 39(3): 567–74
115. 115. H. Peng G.E. Begg S.L. Harper 2000 Biochemical analysis of the Kruppel-associated box (KRAB) J Biol Chem 275 24 18000 10 10748030 1:CAS:528:DC%2BD3cXktlymtro%3D 10.1074/jbc.M001499200 Peng H, Begg GE, Harper SL, et al. Biochemical analysis of the Kruppel-associated box (KRAB). J Biol Chem 2000; 275(24): 18000–10
116. 116. Y. Tanaka T. Shimoike K. Ishii 2000 Selective binding of hepatitis C virus core protein to synthetic oligonucleotides corresponding to the 5′ untranslated region of the viral genome Virology 270 1 229 36 10772995 1:CAS:528:DC%2BD3cXisFers7g%3D 10.1006/viro.2000.0252 Tanaka Y, Shimoike T, Ishii K, et al. Selective binding of hepatitis C virus core protein to synthetic oligonucleotides corresponding to the 5′ untranslated region of the viral genome. Virology 2000; 270(1): 229–36
117. 117. T. Ohno S. Umeda N. Hamasaki 2000 Binding of human mitochondrial transcription factor A, an HMG box protein, to a four-way DNA junction Biochem Biophys Res Commun 271 2 492 8 10799324 1:CAS:528:DC%2BD3cXivFems78%3D 10.1006/bbrc.2000.2656 Ohno T, Umeda S, Hamasaki N, et al. Binding of human mitochondrial transcription factor A, an HMG box protein, to a four-way DNA junction. Biochem Biophys Res Commun 2000; 271(2): 492–8
118. 118. M. Saijo I. Kuraoka C. Masutani 1996 Sequential binding of DNA repair proteins RPA and ERCC1 to XPA in vitro Nucleic Acids Res 24 23 4719 24 8972858 1:CAS:528:DyaK2sXmsFel 10.1093/nar/24.23.4719 Saijo M, Kuraoka I, Masutani C, et al. Sequential binding of DNA repair proteins RPA and ERCC1 to XPA in vitro. Nucleic Acids Res 1996; 24(23): 4719–24
119. 119. M. Wang A. Mahrenholz S.H. Lee 2000 RPA stabilizes the XPA-damaged DNA complex through protein-protein interaction Biochemistry 39 21 6433 9 10828957 1:CAS:528:DC%2BD3cXivVWhs7o%3D 10.1021/bi000472q Wang M, Mahrenholz A, Lee SH. RPA stabilizes the XPA-damaged DNA complex through protein-protein interaction. Biochemistry 2000; 39(21): 6433–9
120. 120. D.J. Hosfield C.D. Mol B. Shen 1998 Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity Cell 95 1 135 46 9778254 1:CAS:528:DyaK1cXmslWls7w%3D 10.1016/S0092-8674(00)81789-4 Hosfield DJ, Mol CD, Shen B, et al. Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity. Cell 1998; 95(1): 135–46
121. 121. L. Tang J. Li D.S. Katz 2000 Determining the DNA bending angle induced by non-specific high mobility group-1 (HMG-1) proteins: a novel method Biochemistry 39 11 3052 60 10715126 1:CAS:528:DC%2BD3cXht1yjsrY%3D 10.1021/bi991819w Tang L, Li J, Katz DS, et al. Determining the DNA bending angle induced by non-specific high mobility group-1 (HMG-1) proteins: a novel method. Biochemistry 2000; 39(11): 3052–60
122. 122. L.R. Burch C.A. Midgley R.A. Currie 2000 Mdm2 binding to a conformationally sensitive domain on p53 can be modulated by RNA FEBS Lett 472 1 93 8 10781812 1:CAS:528:DC%2BD3cXislarsLg%3D 10.1016/S0014-5793(00)01427-7 Burch LR, Midgley CA, Currie RA, et al. Mdm2 binding to a conformationally sensitive domain on p53 can be modulated by RNA. FEBS Lett 2000; 472(1): 93–8
123. 123. J.K. Zutter De K.L. Knight 1999 The hRad51 and RecA proteins show significant differences in cooperative binding to single-stranded DNA J Mol Biol 293 4 769 80 10543966 10.1006/jmbi.1999.3200 1:CAS:528:DyaK1MXmvFOnsbc%3D DeZutter JK, Knight KL. The hRad51 and RecA proteins show significant differences in cooperative binding to single-stranded DNA. J Mol Biol 1999; 293(4): 769–80
124. 124. B. Cheskis L.P. Freedman 1996 Modulation of nuclear receptor interactions by ligands: kinetic analysis using surface plasmon resonance Biochemistry 35 10 3309 18 8605168 1:CAS:528:DyaK28XhtFGltbk%3D 10.1021/bi952283r Cheskis B, Freedman LP. Modulation of nuclear receptor interactions by ligands: kinetic analysis using surface plasmon resonance. Biochemistry 1996; 35(10): 3309–18
125. 125. C.S. Suen T.J. Berrodin R. Mastroeni 1998 A transcriptional coactivator, steroid receptor coactivator-3, selectively augments steroid receptor transcriptional activity J Biol Chem 273 42 27645 53 9765300 1:CAS:528:DyaK1cXntVSgs7c%3D 10.1074/jbc.273.42.27645 Suen CS, Berrodin TJ, Mastroeni R, et al. A transcriptional coactivator, steroid receptor coactivator-3, selectively augments steroid receptor transcriptional activity. J Biol Chem 1998; 273(42): 27645–53
126. 126. L. Galio S. Briquet C. Vaquero 1999 Real-time study of interactions between a composite DNA regulatory region (HIV-1 LTR NRE) and several transcription factors of nuclear extracts Biochem Biophys Res Commun 264 1 6 13 10527831 1:CAS:528:DyaK1MXms1ynt7s%3D 10.1006/bbrc.1999.1365 Galio L, Briquet S, Vaquero C. Real-time study of interactions between a composite DNA regulatory region (HIV-1 LTR NRE) and several transcription factors of nuclear extracts. Biochem Biophys Res Commun 1999; 264(1): 6–13
127. 127. T. Matsuda M. Morikawa M. Haruki 1999 Isolation of TBP-interacting protein (TIP) from a hyperthermophilic archaeon that inhibits the binding of TBP to TATA-DNA FEBS Lett 457 1 38 42 10486559 1:CAS:528:DyaK1MXmtFejsLk%3D 10.1016/S0014-5793(99)01005-4 Matsuda T, Morikawa M, Haruki M, et al. Isolation of TBP-interacting protein (TIP) from a hyperthermophilic archaeon that inhibits the binding of TBP to TATA-DNA. FEBS Lett 1999; 457(1): 38–42
128. 128. M. Passadore N. Bianchi G. Feriotto 1995 Differential effects of distamycin analogues on amplification of human gene sequences by polymerase-chain reaction Biochem J 308 513 9 7772035 1:CAS:528:DyaK2MXmtFers74%3D Passadore M, Bianchi N, Feriotto G, et al. Differential effects of distamycin analogues on amplification of human gene sequences by polymerase-chain reaction. Biochem J 1995; 308: 513–9
129. 129. M. Sastry R. Fiala D.J. Patel 1995 Solution structure of mithramycin dimers bound to partially overlapping sites on DNA J Mol Biol 251 674 689 7666419 1:CAS:528:DyaK2MXotVWitbY%3D 10.1006/jmbi.1995.0464 Sastry M, Fiala R, Patel DJ. Solution structure of mithramycin dimers bound to partially overlapping sites on DNA. J Mol Biol 1995; 251: 674–689
130. 130. J.J. Welch F.J. Rausher III T.A. Beerman 1994 Targeting DNA-binding drugs to sequence-specific transcription factor. DNA complexes J Biol Chem 269 31051 31058 7983044 1:CAS:528:DyaK2cXmslWmsbw%3D Welch JJ, RausherIII FJ, Beerman TA. Targeting DNA-binding drugs to sequence-specific transcription factor. DNA complexes. J Biol Chem 1994; 269: 31051–31058
131. 131. G. Bischoff R. Bischoff E. Birch-Hirschfeld 1998 DNA-drug interaction measurements using surface plasmon resonance J Biomol Struct Dyn 16 2 187 203 9833660 1:CAS:528:DyaK1cXnsVKgsL0%3D 10.1080/07391102.1998.10508239 Bischoff G, Bischoff R, Birch-Hirschfeld E, et al. DNA-drug interaction measurements using surface plasmon resonance. J Biomol Struct Dyn 1998; 16(2): 187–203
132. 132. R. Gambari G. Feriotto C. Rutigliano 2000 Biospecific interaction analysis (BIA) of low-molecular weight DNA-binding drugs J Pharmacol Exp Ther 294 1 370 7 10871335 1:CAS:528:DC%2BD3cXksFyhu78%3D Gambari R, Feriotto G, Rutigliano C, et al. Biospecific interaction analysis (BIA) of low-molecular weight DNA-binding drugs. J Pharmacol Exp Ther 2000; 294(1): 370–7
133. 133. D.L. Boger K.W. Saionz 1999 DNA binding properties of key sandramycin analogues: systematic examination of the intercalation chromophore Bioorg Med Chem 7 2 315 21 10218823 1:CAS:528:DyaK1MXit1equ78%3D 10.1016/S0968-0896(98)00206-5 Boger DL, Saionz KW. DNA binding properties of key sandramycin analogues: systematic examination of the intercalation chromophore. Bioorg Med Chem 1999; 7(2): 315–21
134. 134. K.A. Xavier P.S. Eder T. Giordano 2000 RNA as a drug target: methods for biophysical characterization and screening Trends Biotechnol 18 349 56 10899816 1:CAS:528:DC%2BD3cXltVOgsbg%3D 10.1016/S0167-7799(00)01464-5 Xavier KA, Eder PS, Giordano T. RNA as a drug target: methods for biophysical characterization and screening. Trends Biotechnol 2000; 18: 349–56
135. 135. C.H. Wong M. Hendrix E.S. Priestley 1998 Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA Chem Biol 5 7 397 406 9662506 1:CAS:528:DyaK1cXltVeqsbk%3D 10.1016/S1074-5521(98)90073-4 Wong CH, Hendrix M, Priestley ES, et al. Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA. Chem Biol 1998; 5(7): 397–406
136. 136. D.I. Ryk Van S. Venkatesan 1999 Real-time kinetics of HIV-1 Rev-Rev response element interactions. Definition of minimal binding sites on RNA and protein stoichiometric analysis J Biol Chem 274 17452 63 10364175 10.1074/jbc.274.25.17452 VanRyk DI, Venkatesan S. Real-time kinetics of HIV-1 Rev-Rev response element interactions. Definition of minimal binding sites on RNA and protein stoichiometric analysis. J Biol Chem 1999; 274: 17452–63
137. 137. F.A. Tanious D. Ding D.A. Patrick 2000 Effects of compound structure on Carbazole-DNA complexes: tests of the minor-groove complex models Biochemistry 39 12091 101 11009625 1:CAS:528:DC%2BD3cXmtVGqsb4%3D 10.1021/bi001236i Tanious FA, Ding D, Patrick DA, et al. Effects of compound structure on Carbazole-DNA complexes: tests of the minor-groove complex models. Biochemistry 2000; 39: 12091–101
138. 138. J. Reichert A. Jabs P. Slickers 2000 The IMB Jena Image Library of Biological Macromolecules Nucleic Acids Res 28 246 9 10592237 1:CAS:528:DC%2BD3cXhvVKjt7o%3D 10.1093/nar/28.1.246 and available at Reichert J, Jabs A, Slickers P, et al. The IMB Jena Image Library of Biological Macromolecules. Nucleic Acids Res 2000; 28: 246–9, and available at http://www.imb.jena.de/IMAGE.html
139. 139. Y. Mizushina S. Kamisuki T. Mizuno 2000 Dehydroaltenusin: A mammalian DNA polymerase alpha inhibitor J Biol Chem 275 33957 61 10942777 1:CAS:528:DC%2BD3cXnvVyjtLY%3D 10.1074/jbc.M006096200 Mizushina Y, Kamisuki S, Mizuno T, et al. Dehydroaltenusin: A mammalian DNA polymerase alpha inhibitor. J Biol Chem 2000; 275: 33957–61
140. 140. J.G. Quinn S. O’Neill A. Doyle 2000 Development and application of surface plasmon resonance-based biosensors for the detection of cell-ligand interactions Anal Biochem 281 2 135 43 10870828 1:CAS:528:DC%2BD3cXkt1Sntrk%3D 10.1006/abio.2000.4564 Quinn JG, O’Neill S, Doyle A, et al. Development and application of surface plasmon resonance-based biosensors for the detection of cell-ligand interactions. Anal Biochem 2000; 281(2): 135–43
141. 141. Affinity Sensors On Line. IAsys{R} Application Note 5.2. Available at: URL: http://w.affinity-sensors.com/pdf/appnotes/APPNOTES5-2.PDF [Accessed 2001 April]
142. 142. Affinity Sensors On Line. IAsys{R} Application Note 5.3 Available at: URL: http://w.affinity-sensors.com/pdf/appnotes/APPNOTES5-3.PDF [Accessed 2001 April]
143. 143. E. Uhlmann A. Peyman 1990 Antisense oligonucleotides: a new therapeutic principle Chem Rev 90 543 84 1:CAS:528:DyaK3cXktVKluro%3D 10.1021/cr00102a001 Uhlmann E, Peyman A. Antisense oligonucleotides: a new therapeutic principle. Chem Rev 1990; 90: 543–84
144. 144. W.M. McShean R.D. Rossen A.H. Laughter 1992 Inhibition of transcription of HIV-1 in infected human cells by oligodeoxynucleotides designed to form DNA triple helices J Biol Chem 267 5712 21 McShean WM, Rossen RD, Laughter AH, et al. Inhibition of transcription of HIV-1 in infected human cells by oligodeoxynucleotides designed to form DNA triple helices. J Biol Chem 1992; 267: 5712–21
145. 145. R. Morishita T. Sugimoto M. Aoki 1997 In vivo transfection of cis element ‘decoy’ against nuclear factor-kappaB binding site prevents myocardial infarction Nat Med 3 894 9 9256281 1:CAS:528:DyaK2sXltVOhs7g%3D 10.1038/nm0897-894 Morishita R, Sugimoto T, Aoki M, et al. In vivo transfection of cis element ‘decoy’ against nuclear factor-kappaB binding site prevents myocardial infarction. Nat Med 1997; 3: 894–9
146. 146. L. Good P.E. Nielsen 1997 Progress in developing PNA as a gene-targeted drug Antisense Nucleic Acid Drug Dev 7 431 7 9303195 1:CAS:528:DyaK2sXmtFamt7o%3D 10.1089/oli.1.1997.7.431 Good L, Nielsen PE. Progress in developing PNA as a gene-targeted drug. Antisense Nucleic Acid Drug Dev 1997; 7: 431–7
147. 147. A.P. Simoes-Wust R.A. Olie O. Gautschi 2000 Bcl-xl antisense treatment induces apoptosis in breast carcinoma cells Int J Cancer 87 4 582 90 10918201 1:CAS:528:DC%2BD3cXlvVyms7w%3D 10.1002/1097-0215(20000815)87:4<582::AID-IJC19>3.0.CO;2-P Simoes-Wust AP, Olie RA, Gautschi O, et al. Bcl-xl antisense treatment induces apoptosis in breast carcinoma cells. Int J Cancer 2000; 87(4): 582–90
148. 148. N. Agarwal A.M. Gewirtz 1999 Oligonucleotide therapeutics for hematologic disorders Biochim Biophys Acta 1489 1 85 96 10806999 1:CAS:528:DyaK1MXns1Sltbs%3D 10.1016/S0167-4781(99)00142-6 Agarwal N, Gewirtz AM. Oligonucleotide therapeutics for hematologic disorders. Biochim Biophys Acta 1999; 1489(1): 85–96
149. 149. G. Lacerra H. Sierakowska C. Carestia 2000 Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients Proc Natl Acad Sci U S A 97 17 9591 6 10944225 1:CAS:528:DC%2BD3cXmtVentr4%3D 10.1073/pnas.97.17.9591 Lacerra G, Sierakowska H, Carestia C, et al. Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients. Proc Natl Acad Sci U S A 2000; 97(17): 9591–6
150. 150. B. Persson K. Stenhag P. Nilsson 1997 Analysis of oligonucleotide probe affinities using surface plasmon resonance: a means for mutational scanning Anal Biochem 246 1 34 44 9056180 1:CAS:528:DyaK2sXhsFGqsbg%3D 10.1006/abio.1996.9988 Persson B, Stenhag K, Nilsson P, et al. Analysis of oligonucleotide probe affinities using surface plasmon resonance: a means for mutational scanning. Anal Biochem 1997; 246(1): 34–44
151. 151. K.K. Jensen H. Orum P.E. Nielsen 1997 Kinetics for hybridization of peptide nucleic acids (PNA) with DNA and RNA studied with the BIAcore technique Biochemistry 36 16 5072 7 9125529 1:CAS:528:DyaK2sXit1Krsbc%3D 10.1021/bi9627525 Jensen KK, Orum H, Nielsen PE, et al. Kinetics for hybridization of peptide nucleic acids (PNA) with DNA and RNA studied with the BIAcore technique. Biochemistry 1997; 36(16): 5072–7
152. 152. C. Rutigliano N. Bianchi M. Tomassetti 1998 Surface plasmon resonance for real-time monitoring of molecular interactions between a triple helix forming oligonucleotide and the Sp1 binding sites of human Ha-ras promoter: effects of the DNA-binding drug chromomycin Int J Oncol 12 2 337 43 9458359 1:CAS:528:DyaK1cXos1WrsA%3D%3D Rutigliano C, Bianchi N, Tomassetti M, et al. Surface plasmon resonance for real-time monitoring of molecular interactions between a triple helix forming oligonucleotide and the Sp1 binding sites of human Ha-ras promoter: effects of the DNA-binding drug chromomycin. Int J Oncol 1998; 12(2): 337–43
153. 153. J.R. Krone R.W. Nelson D. Dogruel 1997 BIA/MS: interfacing biomolecular interaction analysis with mass spectrometry Anal Biochem 244 1 124 32 9025918 1:CAS:528:DyaK2sXltlahtw%3D%3D 10.1006/abio.1996.9871 Krone JR, Nelson RW, Dogruel D, et al. BIA/MS: interfacing biomolecular interaction analysis with mass spectrometry. Anal Biochem 1997; 244(1): 124–32
154. 154. R.W. Nelson J.R. Krone O. Jansson 1997 Surface plasmon resonance biomolecular interaction analysis mass spectrometry. 1. Chip-based analysis Anal Chem 69 21 4363 8 9360491 1:CAS:528:DyaK2sXmt12ms74%3D 10.1021/ac970538w Nelson RW, Krone JR, Jansson O. Surface plasmon resonance biomolecular interaction analysis mass spectrometry. 1. Chip-based analysis. Anal Chem 1997; 69(21): 4363–8
155. 155. C.P. Sonksen E. Nordhoff O. Jansson 1998 Combining MALDI mass spectrometry and biomolecular interaction analysis using a biomolecular interaction analysis instrument Anal Chem 70 13 2731 6 9666738 1:STN:280:DyaK1czjtFWrug%3D%3D 10.1021/ac9800457 Sonksen CP, Nordhoff E, Jansson O, et al. Combining MALDI mass spectrometry and biomolecular interaction analysis using a biomolecular interaction analysis instrument. Anal Chem 1998; 70(13): 2731–6
156. 156. R.W. Nelson D. Nedelkov K.A. Tubbs 2000 Biosensor chip mass spectrometry: a chip-based proteomics approach Electrophoresis 21 6 1155 63 10786888 1:CAS:528:DC%2BD3cXis12ku7s%3D 10.1002/(SICI)1522-2683(20000401)21:6<1155::AID-ELPS1155>3.0.CO;2-X Nelson RW, Nedelkov D, Tubbs KA. Biosensor chip mass spectrometry: a chip-based proteomics approach. Electrophoresis 2000; 21(6): 1155–63
157. 157. E. Danelian A. Karlen R. Karlsson 2000 SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans J Med Chem 43 11 2083 6 10841786 1:CAS:528:DC%2BD3cXjtFKiu7w%3D 10.1021/jm991156g Danelian E, Karlen A, Karlsson R, et al. SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans. J Med Chem 2000; 43(11): 2083–6