Kinetic analysis of the interaction between HIV-1 protease and inhibitors using optical biosensor technology

Analytical Biochemistry

Volumn 279, Issue 1, 2000, Pages 71-78

  Markgren, Per Olof ^a   Hämäläinen, Markku ^b   Danielson, U Helena ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b BIACORE AB   (Sweden)

Author keywords

Affinity; Biacore; Binding; Biosensor; Dissociation rate; HIV; Indinavir; Inhibitor; Interaction; Low molecular weight; Nelfinavir; Protease; Ritonavir; Saquinavir

Indexed keywords

BIOSENSORS; DISSOCIATION; MOLECULAR WEIGHT; SURFACE PLASMON RESONANCE;

AFFINITY; BIACORE; BINDING; DISSOCIATION RATES; INDINAVIR; INHIBITOR; INTERACTION; LOW MOLECULAR WEIGHT; NELFINAVIR; PROTEASE; RITONAVIR; SAQUINAVIR;

ENZYME INHIBITION;

INDINAVIR; NELFINAVIR; PROTEINASE; RITONAVIR; SAQUINAVIR;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION KINETICS; CONCENTRATION (PARAMETERS); DISSOCIATION CONSTANT; ENZYME IMMOBILIZATION; ENZYME INHIBITOR COMPLEX; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0343484958     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.1999.4467     Document Type: Article

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