-
1
-
-
9044242095
-
Binding characteristics and antitumor properties of 1A10 bispecific antibody recognizing gp40 and human transferrin receptor
-
AMOROSO, A.R., CLARK, J.I., LITWIN, S., HSIEH-MA, S., SHI, T., ALPAUGH, R.K., ADAMS, G.P., WOLF, E.J., RING, D.B. and WEINER, L.M., Binding characteristics and antitumor properties of 1A10 bispecific antibody recognizing gp40 and human transferrin receptor. Cancer Res., 56, 113-120 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 113-120
-
-
Amoroso, A.R.1
Clark, J.I.2
Litwin, S.3
Hsieh-Ma, S.4
Shi, T.5
Alpaugh, R.K.6
Adams, G.P.7
Wolf, E.J.8
Ring, D.B.9
Weiner, L.M.10
-
2
-
-
9544250404
-
Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library
-
BEGENT, R.H.J. and 12 OTHERS, Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library. Nat. Med., 2, 979-984 (1996).
-
(1996)
Nat. Med.
, vol.2
, pp. 979-984
-
-
Begent, R.H.J.1
-
3
-
-
0028926012
-
Radiolabeled chimeric anti-CEA monoclonal antibody compared with the original mouse monoclonal antibody for surgically treated colorectal carcinoma
-
BUCHEGGER, F., MACH, J.P., PÈLEGRIN, A., GILLET, M., VOGEL, C.A., BUCLIN, T., RYSER, J.E., DELALOYE, B. and BISCHOF-DELALOYE, A., Radiolabeled chimeric anti-CEA monoclonal antibody compared with the original mouse monoclonal antibody for surgically treated colorectal carcinoma. J. nucl. Med., 36, 420-429 (1995).
-
(1995)
J. Nucl. Med.
, vol.36
, pp. 420-429
-
-
Buchegger, F.1
Mach, J.P.2
Pèlegrin, A.3
Gillet, M.4
Vogel, C.A.5
Buclin, T.6
Ryser, J.E.7
Delaloye, B.8
Bischof-Delaloye, A.9
-
4
-
-
0025330441
-
2 fragments are more efficient and less toxic than intact anti-CEA antibodies in radioimmunotherapy of large human colon carcinoma grafted in nude mice
-
2 fragments are more efficient and less toxic than intact anti-CEA antibodies in radioimmunotherapy of large human colon carcinoma grafted in nude mice. J. Nucl. Med., 31, 1035-1044 (1990).
-
(1990)
J. Nucl. Med.
, vol.31
, pp. 1035-1044
-
-
Buchegger, F.1
Pèlegrin, A.2
Delaloye, B.3
Bischof-Delaloye, A.4
Mach, J.-P.5
-
5
-
-
0029851132
-
Preparation, characterisation and tumor targeting of cross-linked divalent and trivalent anti-tumour Fab' fragments
-
CASEY, J.L., KING, D.J., CHAPLIN, L.C., HAINES, A.M.R., PEDLEY, R.B., MOUNTAIN, A., YARRANTON, G.T. and BEGENT, R.H.J., Preparation, characterisation and tumor targeting of cross-linked divalent and trivalent anti-tumour Fab' fragments. Brit. J. Cancer, 74, 1397-1405 (1996).
-
(1996)
Brit. J. Cancer
, vol.74
, pp. 1397-1405
-
-
Casey, J.L.1
King, D.J.2
Chaplin, L.C.3
Haines, A.M.R.4
Pedley, R.B.5
Mountain, A.6
Yarranton, G.T.7
Begent, R.H.J.8
-
6
-
-
0025553414
-
Affinity enhancement of bispecific antibody against two different epitopes in the same antigen
-
CHEONG, H.S., CHANG, J.S., PARK, J.M. and BYUN, S.M., Affinity enhancement of bispecific antibody against two different epitopes in the same antigen. Biochem. biophys. Res. Comm., 173, 795-800 (1990).
-
(1990)
Biochem. Biophys. Res. Comm.
, vol.173
, pp. 795-800
-
-
Cheong, H.S.1
Chang, J.S.2
Park, J.M.3
Byun, S.M.4
-
7
-
-
0028358243
-
Chemical synthesis of bispecific monoclonal antibodies: Potential advantages in immunoassay systems
-
COOK, A.G. and WOOD, P.J., Chemical synthesis of bispecific monoclonal antibodies: potential advantages in immunoassay systems. J. Immunol. Methods, 171, 227-237 (1994).
-
(1994)
J. Immunol. Methods
, vol.171
, pp. 227-237
-
-
Cook, A.G.1
Wood, P.J.2
-
8
-
-
0022570716
-
2 fragments from monoclonal anticarcinoembryonic antigen antibodies
-
2 fragments from monoclonal anticarcinoembryonic antigen antibodies. J. clin. Invest., 77, 301-311 (1986).
-
(1986)
J. Clin. Invest.
, vol.77
, pp. 301-311
-
-
Delaloye, B.1
Bischof-Delaloye, A.2
Buchegger, F.3
Von Fliedner, V.4
Grob, J.-P.5
Volant, J.C.6
Pettavel, J.7
Mach, J.-P.8
-
9
-
-
0027192897
-
Construction of a bispecific antibody reacting with the alpha-and beta-chains of the human IL-2 receptor. High affinity cross-linking and high anti-proliferative efficiency
-
FRANÇOIS, C., BOEFFARD, F., KALUZA, B., WEIDLE, U.H. and JACQUES, Y., Construction of a bispecific antibody reacting with the alpha-and beta-chains of the human IL-2 receptor. High affinity cross-linking and high anti-proliferative efficiency. J. Immunol., 150, 4610-4619 (1993).
-
(1993)
J. Immunol.
, vol.150
, pp. 4610-4619
-
-
François, C.1
Boeffard, F.2
Kaluza, B.3
Weidle, U.H.4
Jacques, Y.5
-
10
-
-
0024407253
-
Antigenic sites in carcinoembryonic antigen
-
HAMMARSTRÖM, S. and 30 OTHERS, Antigenic sites in carcinoembryonic antigen. Cancer Res., 49, 4852-4858 (1989).
-
(1989)
Cancer Res.
, vol.49
, pp. 4852-4858
-
-
Hammarström, S.1
-
11
-
-
0027197493
-
"Diabodies": Small bivalent and bispecific antibody fragments
-
HOLLIGER, P., PROSPERO, T. and WINTER, G., "Diabodies": small bivalent and bispecific antibody fragments. Proc. nat. Acad. Sci. (Wash.), 90, 6444-6448 (1993).
-
(1993)
Proc. Nat. Acad. Sci. (Wash.)
, vol.90
, pp. 6444-6448
-
-
Holliger, P.1
Prospero, T.2
Winter, G.3
-
12
-
-
0029779766
-
2
-
2. J. nucl. Med., 37, 1504-1510 (1997).
-
(1997)
J. Nucl. Med.
, vol.37
, pp. 1504-1510
-
-
Juweid, M.E.1
Sharkey, R.M.2
Behr, T.3
Swayne, L.C.4
Dunn, R.5
Siegel, J.6
Goldenberg, D.M.7
-
13
-
-
0027208577
-
Radioimmunotherapy of B-cell lymphoma with [131I]anti-B1 (anti-CD20) antibody
-
KAMINSKI, M.S. and 12 OTHERS, Radioimmunotherapy of B-cell lymphoma with [131I]anti-B1 (anti-CD20) antibody. N. Engl. J. Med., 329, 459-465 (1993).
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 459-465
-
-
Kaminski, M.S.1
-
14
-
-
0029587051
-
Preparation and preclinical evaluation of humanised A33 immunoconjugates for radioimmunotherapy
-
KING, D.J. and 19 OTHERS, Preparation and preclinical evaluation of humanised A33 immunoconjugates for radioimmunotherapy. Brit. J. Cancer, 72, 1364-1372 (1995).
-
(1995)
Brit. J. Cancer
, vol.72
, pp. 1364-1372
-
-
King, D.J.1
-
15
-
-
0027428816
-
Bispecific monoclonal antibody-mediated targeting of an indium-111-labeled DTPA dimer to primary colorectal tumors: Pharmacokinetics, biodistribution, scintigraphy and immune response
-
LE DOUSSAL, J.M., CHETANNEAU, A., GRUAZ-GUYON, A., MARTIN, M., GAUTHEROT, E., LEHUR, P.A., CHATAL, J.F., DELAAGE, M. and BARBET, J., Bispecific monoclonal antibody-mediated targeting of an indium-111-labeled DTPA dimer to primary colorectal tumors: pharmacokinetics, biodistribution, scintigraphy and immune response. J. nucl Med., 34, 1662-1671 (1993).
-
(1993)
J. Nucl Med.
, vol.34
, pp. 1662-1671
-
-
Le Doussal, J.M.1
Chetanneau, A.2
Gruaz-Guyon, A.3
Martin, M.4
Gautherot, E.5
Lehur, P.A.6
Chatal, J.F.7
Delaage, M.8
Barbet, J.9
-
16
-
-
0025943152
-
Imaging and therapy with monoclonal antibodies in non-hematopoietic tumors
-
MACH, J.-P., PÈLEGRIN, A. and BUCHEGGER, F., Imaging and therapy with monoclonal antibodies in non-hematopoietic tumors. Curr. Opin. Immunol., 3, 685-693 (1991).
-
(1991)
Curr. Opin. Immunol.
, vol.3
, pp. 685-693
-
-
Mach, J.-P.1
Pèlegrin, A.2
Buchegger, F.3
-
17
-
-
9444289885
-
Clinical utility of external immunoscintigraphy with the IMMU-44 technetium-99m Fab' antibody fragment in patients undergoing surgery for carcinoma of the colon and rectum: Results of a pivotal, phase III trial. The Immunomedics Study Group
-
MOFFAT, F.L., JR., PINSKY, C.M., HAMMERSHAIMB, L., PETRELLI, N.J., PATT, Y.Z., WHALEY, F.S. and GOLDENBERG, D.M., Clinical utility of external immunoscintigraphy with the IMMU-44 technetium-99m Fab' antibody fragment in patients undergoing surgery for carcinoma of the colon and rectum: results of a pivotal, phase III trial. The Immunomedics Study Group. J. clin. Oncol., 14, 2295-2305 (1996).
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 2295-2305
-
-
Moffat F.L., Jr.1
Pinsky, C.M.2
Hammershaimb, L.3
Petrelli, N.J.4
Patt, Y.Z.5
Whaley, F.S.6
Goldenberg, D.M.7
-
18
-
-
0028945817
-
High-affinity antigen binding by chelating recombinant antibodies (CRAbs)
-
NERI, D., MOMO, M., PROSPERO, T. and WINTER, G., High-affinity antigen binding by chelating recombinant antibodies (CRAbs). J. mol. Biol., 246, 367-373 (1995).
-
(1995)
J. Mol. Biol.
, vol.246
, pp. 367-373
-
-
Neri, D.1
Momo, M.2
Prospero, T.3
Winter, G.4
-
19
-
-
0030738617
-
New protein engineering approaches to multivalent and bispecilic antibody fragments
-
PLUCKTHUN, A. and PACK, P., New protein engineering approaches to multivalent and bispecilic antibody fragments. Immunotechnology, 3, 83-105 (1997).
-
(1997)
Immunotechnology
, vol.3
, pp. 83-105
-
-
Pluckthun, A.1
Pack, P.2
-
20
-
-
0029163551
-
Phase II trial of 131I-B1 (anti-CD20) antibody therapy with autologous stem cell transplantation for relapsed B cell lymphomas
-
PRESS, O.W., EARY, J.F., APPELBAUM, F.R., MARTIN, P.J., NELP, W.B., GLENN, S., FISHER, D.R., PORTER, B., MATTHEWS, D.C., GOOLEY, T. and BERNSTEIN, I.D., Phase II trial of 131I-B1 (anti-CD20) antibody therapy with autologous stem cell transplantation for relapsed B cell lymphomas. Lancet. 346, 336-340 (1995).
-
(1995)
Lancet.
, vol.346
, pp. 336-340
-
-
Press, O.W.1
Eary, J.F.2
Appelbaum, F.R.3
Martin, P.J.4
Nelp, W.B.5
Glenn, S.6
Fisher, D.R.7
Porter, B.8
Matthews, D.C.9
Gooley, T.10
Bernstein, I.D.11
-
21
-
-
0029821117
-
Cytokine targeting in tumors using a bispecific antibody directed against carcinoembryonic antigen and tumor necrosis factor α
-
ROBERT, B., MACH, J.P., MANI, J.C., YCHOU, M., FOLLI, S., ARTUS, J.C. and PÈLEGRIN, A., Cytokine targeting in tumors using a bispecific antibody directed against carcinoembryonic antigen and tumor necrosis factor α. Cancer Res., 56, 4758-4765 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 4758-4765
-
-
Robert, B.1
Mach, J.P.2
Mani, J.C.3
Ychou, M.4
Folli, S.5
Artus, J.C.6
Pèlegrin, A.7
-
22
-
-
0028171625
-
Dimeric recombinant IgA directed against carcino-embryonic antigen, a novel tool for carcinoma localization
-
TERSKIKH, A., COUTY, S., PÈLEGRIN, A., HARDMAN, N., HUNZIKER, W. and MACH, J.-P., Dimeric recombinant IgA directed against carcino-embryonic antigen, a novel tool for carcinoma localization. Moll. Immunol., 31, 1313-1319 (1994).
-
(1994)
Moll. Immunol.
, vol.31
, pp. 1313-1319
-
-
Terskikh, A.1
Couty, S.2
Pèlegrin, A.3
Hardman, N.4
Hunziker, W.5
Mach, J.-P.6
-
23
-
-
0027305843
-
Marked increase in the secretion of a fully antigenic recombinant CEA obtained by deletion of its hydrophobic tail
-
TERSKIKH, A., MACH, J.-P. and PÈLEGRIN, A., Marked increase in the secretion of a fully antigenic recombinant CEA obtained by deletion of its hydrophobic tail. Mol. Immunol., 30, 921-927 (1993).
-
(1993)
Mol. Immunol.
, vol.30
, pp. 921-927
-
-
Terskikh, A.1
Mach, J.-P.2
Pèlegrin, A.3
-
24
-
-
0031049701
-
"Peptabody": A new type of high avidity binding protein
-
TERSKIKH, A.V., LE DOUSSAL, J.M., CRAMERI, R., FISCH, I., MACH, J.P. and KAJAVA, A.V., "Peptabody": a new type of high avidity binding protein. Proc. nat. Acad. Sci. (Wash.), 94, 1663-1668 (1997).
-
(1997)
Proc. Nat. Acad. Sci. (Wash.)
, vol.94
, pp. 1663-1668
-
-
Terskikh, A.V.1
Le Doussal, J.M.2
Crameri, R.3
Fisch, I.4
Mach, J.P.5
Kajava, A.V.6
-
25
-
-
0027935133
-
Phase I/II study of iodine 131-labeled monoclonal antibody A33 in patients with advanced colon cancer
-
WELT, S., DIVGI, C.R., KEMENY, N., FINN, R.D., SCOTT, A.M., GRAHAM, M., GERMAIS, J.S., RICHARDS, E.C., LARSON, S.M., OETTGEN, H.F. and OLD, L.J., Phase I/II study of iodine 131-labeled monoclonal antibody A33 in patients with advanced colon cancer. J. clin. Oncol., 12, 1561-1571 (1994).
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 1561-1571
-
-
Welt, S.1
Divgi, C.R.2
Kemeny, N.3
Finn, R.D.4
Scott, A.M.5
Graham, M.6
Germais, J.S.7
Richards, E.C.8
Larson, S.M.9
Oettgen, H.F.10
Old, L.J.11
-
26
-
-
0030020157
-
Preparation of a trivalent antigen-binding construct using polyoxime chemistry: Improved biodistribution and potential for therapeutic application
-
WERLEN, R.C., LANKINEN, M., OFFORD, R.E., SCHUBIGER, P.A., SMITH, A. and ROSE, K., Preparation of a trivalent antigen-binding construct using polyoxime chemistry: improved biodistribution and potential for therapeutic application. Cancer Res., 56, 809-815 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 809-815
-
-
Werlen, R.C.1
Lankinen, M.2
Offord, R.E.3
Schubiger, P.A.4
Smith, A.5
Rose, K.6
-
27
-
-
0032498554
-
2 in patients with non-reseclable liver metastases from colorectal cancer
-
2 in patients with non-reseclable liver metastases from colorectal cancer. Int. J. Cancer. 75, 615-619 (1998).
-
(1998)
Int. J. Cancer.
, vol.75
, pp. 615-619
-
-
Ychou, M.1
Pèlegrin, A.2
Faurous, P.3
Robert, B.4
Saccavini, J.C.5
Guerreau, D.6
Rossi, J.F.7
Fabbro, M.8
Buchegger, F.9
Mach, J.P.10
Artus, J.C.11
|