CD8+ tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis

Journal of Immunology

Volumn 167, Issue 9, 2001, Pages 5042-5051

  Radoja, S ^a   Saio, M ^a   Schaer, D ^a   Koneru, M ^a   Vukmanovic, S ^a   Frey, A B ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; PERFORIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEASOME; PROTEIN KINASE C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; CYTOLYSIS; EXOCYTOSIS; MALE; MICROTUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MODEL;

EID: 0035500642     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.9.5042     Document Type: Article

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