Identification of genes coding for tumor antigens recognized by cytolytic T lymphocytes

Methods: A Companion to Methods in Enzymology

Volumn 12, Issue 2, 1997, Pages 125-142

  De Plaen, Etienne ^a,b   Lurquin, Christophe ^a,b   Lethé, Bernard ^a,b   Van Der Bruggen, Pierre ^a,b   Brichard, Vincent ^a,b   Renauld, Jean Christophe ^a,b   Coulie, Pierre ^a,b   Van Pel, Aline ^a,b   Boon, Thierry ^a,b  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; TUMOR ANTIGEN;

ARTICLE; CYTOTOXIC T LYMPHOCYTE; GENE EXPRESSION; GENETIC TRANSFECTION; HISTOCOMPATIBILITY GENE; PRIORITY JOURNAL;

EID: 0031172078     PISSN: 10462023     EISSN: None     Source Type: Journal    
DOI: 10.1006/meth.1997.0462     Document Type: Article

References (85)

1. Allen J. M., Seed B. Isolation and expression of functional high affinity Fc receptor complementary DNAs. Science. 243:1989;378-381.
2. Anichini A., Fossati G., Parmiani G. Clonal analysis of the cytolytic T-cell response to human tumors. Immunol. Today. 8:1987;385-389.
3. Aruffo A., Seed B. Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc. Natl. Acad. Sci. USA. 84:1987;8573-8577.
4. Ausubel F. M., Brent R., Kingston R. E., Moore D. D., Seidman J. G., Smith J. A., Struhl K. Current Protocols in Molecular Biology. 1993;Greene Publishing Associates/Wiley, New York.
5. Barnstable C. J., Bodmer W. F., Brown G., Galfre G., Milstein C., Williams A. F., Ziegler A. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell-surface antigens - New tools for genetic analysis. Cell. 14:1978;9-20.
6. Bernard H.-U., Krämmer G., Röwekamp W. G. Construction of a fusion gene that confers resistance against hygromycin B to mammalian cells in culture. Exp. Cell. Biol. 158:1985;237-243.
7. Beyaert R., Vanhaesebroeck B., Suffys P., Van Roy F., Fiers W. Lithium chloride potentiates tumor necrosis factor-mediated cytotoxicity in vitro and in vivo. Proc. Natl. Acad. Sci. USA. 86:1989;9494-9498.
8. Bjorkman P. J., Saper M. A., Samraoui B., Bennett W. S., Strominger J. L., Wiley D. C. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature. 329:1987;512-518.
9. Bodmer H., Ogg G., Gotch F., McMichael A. Anti-HLA-A2 antibody-enhancement of peptide association with HLA-A2 as detected by cytotoxic T lymphocytes. Nature. 342:1989;443-446.
10. Boël P., Wildmann C., Sensi M. L., Brasseur R., Renauld J.-C., Coulie P., Boon T., van der Bruggen P. BAGE, a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes. Immunity. 2:1995;167-175.
11. Boon T., Cerottini J.-C., Van den Eynde B., van der Bruggen P., Van Pel A. Tumor antigens recognized by T lymphocytes. Annu. Rev. Immunol. 12:1994;337-365.
12. Brichard V., Herman J., Van Pel A., Wildmann C., Gaugler B., Wölfel T., Boon T., Lethé B. A tyrosinase nonapeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes. Eur. J. Immunol. 26:1996;224-230.
13. Brichard V., Van Pel A., Wölfel T., Wölfel C., De Plaen E., Lethé B., Coulie P., Boon T. The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J. Exp. Med. 178:1993;489-495.
14. Brichard V., Warnier G., Van Pel A., Morlighem G., Lucas S., Boon T. Individual differences in the orientation of the cytolytic T cell response against mouse tumor P815. Eur. J. Immunol. 25:1995;664-671.
15. Brunner K. T., MacDonald H. R., Cerottini J.-C. Antigenic specificity of the cytolytic T lymphocyte (CTL) response to murine sarcoma virus-induced tumors. II. Analysis of the clonal progeny of CTL precursors stimulated in vitro with syngeneic tumor cells. J. Immunol. 124:1980;1627-1634.
16. Corsaro C. M., Pearson M. L. Enhancing the efficiency of DNA mediated gene transfer in mammalian cells. Somat. Cell Mol. Genet. 7:1981;603-616.
17. Coulie P. G., Brichard V., Van Pel A., Wölfel T., Schneider J., Traversari C., Mattei S., De Plaen E., Lurquin C., Szikora J.-P., Renauld J.-C., Boon T. A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J. Exp. Med. 180:1994;35-42.
18. Cox A. L., Skipper J., Chen Y., Henderson R. A., Darrow T. L., Shabanowitz J., Engelhard V. H., Hunt D. F., Slingluff C. L. Jr. Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines. Science. 264:1994;716-719.
19. Danna K. J., Nathans D. Bidirectional replication of simian virus 40 DNA. Proc. Natl. Acad. Sci. USA. 69:1972;3097-3100.
20. Darrow T. L., Slingluff C. L. J., Seigler H. F. The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens. J. Immunol. 142:1989;3329-3335.
21. de Bergeyck V., De Plaen E., Chomez P., Boon T., Van Pel A. An intracisternal A particle sequence codes for an antigen recognized by syngeneic cytolytic T lymphocytes on a mouse spontaneous leukemia. Eur. J. Immunol. 24:1994;2203-2212.
22. ---. Proc. Natl. Acad. Sci. USA. 85:1988;2274-2278.
23. Deb S., DeLucia A. L., Baur C.-P., Koff A., Tegtmeyer P. Domain structure of the simian virus 40 core origin of replication. Mol. Cell. Biol. 6:1986;1663-1670.
24. Eckhart W. Virology. 1990;Raven Press, Ltd. New York. p. 1593-1607.
25. Engelhard V. H. Structure of peptides associated with class I and class II MHC molecules. Annu. Rev. Immunol. 12:1994;181-207.
26. Ennis P. D., Zemmour J., Salter R. D., Parham P. Rapid cloning of HLA-A, B cDNA by using the polymerase chain reaction: Frequency and nature of errors produced in amplification. Proc. Natl. Acad. Sci. USA. 87:1990;2833-2837.
27. Espevik T., Nissen-Meyer J. A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J. Immunol. Methods. 95:1986;99-105.
28. Falk K., Rötzschke O., Rammensee H.-G. Cellular peptide composition governed by major histocompatibility complex class I molecules. Nature. 348:1990;248-251.
29. Falk K., Rötzschke O., Stevanovic S., Jung G., Rammensee H.-G. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature. 351:1991;290-296.
30. Fareed G. C., Garon C. F., Salzman N. P. Origin and direction of simian virus 40 deoxyribonucleic acid replication. J. Virol. 10:1972;484.
31. Fiers W., Contreras R., Haegeman G., Rogiers R., van de Voorde A., van Heuverswywn H., van Herreweghe J., Volckaert G., Ysebaert M. The complete nucleotide sequence of SV40 DNA. Nature (London). 273:1978;113-120.
32. Gaugler B., Van den Eynde B., van der Bruggen P., Romero P., Gaforio J. J., De Plaen E., Lethé B., Brasseur F., Boon T. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. J. Exp. Med. 179:1994;921-930.
33. Gluzman Y. SV40-transformed simian cells support the replication of early SV40 mutants. Cell. 23:1981;175-182.
34. Guilloux Y., Lucas S., Brichard V., Van Pel A., Viret C., De Plaen E., Brasseur F., Lethé B., Jotereau F., Boon T. A peptide recognized by human cytolytic T lymphocytes on HLA-A2 melanomas is encoded by an intron sequence of theN. J. Exp. Med. 183:1996;1173-1183.
35. Hansen M. B., Nielsen S. E., Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J. Immunol. Methods. 119:1989;203-210.
36. Hérin M., Lemoine C., Weynants P., Vessière F., Van Pel A., Knuth A., Devos R., Boon T. Production of stable cytolytic T-cell clones directed against autologous human melanoma. Int. J. Cancer. 39:1987;390-396.
37. Hoeijmakers J. H. J., Odijk H., Westerveld A. Differences between rodent and human cell lines in the amount of integrated DNA after transfection. Exp. Cell Res. 169:1987;111-119.
38. Hunt D. F., Henderson R. A., Shabanowitz J., Sakaguchi K., Michel H., Sevilir N., Cox A., Appela E., Engelhard V. H. Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. Science. 255:1992;1261-1263.
39. Karttunen J., Sanderson S., Shastri N. Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens. Proc. Natl. Acad. Sci. USA. 89:1992;6020-6024.
40. Kawakami Y., Eliyahu S., Delgado C. H., Robbins P. F., Rivoltini L., Topalian S. L., Miki T., Rosenberg S. A. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc. Natl. Acad. Sci. USA. 91:1994;3515-3519.
41. Kawakami Y., Zakut R., Topalian S. L., Stötter H., Rosenberg S. A. Shared human melanoma antigens. Recognition by tumor-infiltrating lymphocytes in HLA-A2.1-transfected melanomas. J. Immunol. 148:1992;638-643.
42. Klein G., Sjögren H., Klein E., Hellström K. E. Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host. Cancer Res. 20:1960;1561-1572.
43. Knuth A., Danowski B., Oettgen H. F., Old L. T-cell mediated cytotoxicity against autologous malignant melanoma: Analysis with interleukin-2-dependent T-cell cultures. Proc. Natl. Acad. Sci. USA. 81:1984;3511-3515.
44. Kozak M. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15:1987;8125-8132.
45. Kripke M. L. Antigenicity of murine skin tumors induced by ultraviolet light. J. Natl. Cancer Inst. 53:1974;1333-1336.
46. Levy J. P., Leclerc J. C. The murine-sarcoma-virus-induced tumor: Exceptions or general model in tumor immunology. Adv. Cancer Res. 24:1977;1-59.
47. Li J. J., Kelly T. J. Simian virus 40 DNA replication in vitro: Specificity of initiation and evidence for bidirectional replication. Mol. Cell. Biol. 5:1985;1238-1246.
48. d. Cell. 58:1989;293-303.
49. Madden D. R., Gorga J. C., J. L. S., Wiley D. C. The structure of HLA-B27 reveals nonamer self peptides bound in an extended conformation. Nature. 353:1991;321-325.
50. Maryanski J. L., Boon T. Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. IV. Analysis of variant-specific antigens by selection of antigen-loss variants with cytolytic T cell clones. Eur. J. Immunol. 12:1982;406-412.
51. Maryanski J. L., Van Snick J., Cerottini J. C., Boon T. Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. III. Clonal analysis of the syngeneic cytolytic T lymphocyte response. Eur. J. Immunol. 12:1982;401-406.
52. McMichael A. J., Parham P., Rust N., Brodsky F. A monoclonal antibody that recognized an antigenic determinant shared by HLA-A2 and B17. Hum. Immunol. 1:1980;121-129.
53. Mukherji B., MacAlister T. J. Clonal analysis of cytotoxic T cell response against human melanoma. J. Exp. Med. 158:1983;240-245.
54. Nicolas J. F., Berg P. Regulation of expression of genes transduced into embryonal carcinoma cells. CSH Conferences Cell Prolif. 10:1983;469-485.
55. Old L. J., Boyse E. A., Clarke D. A., Carswell E. A. Antigenic properties of chemically-induced tumors. Ann. N.Y. Acad. Sci. 10:1962;80-106.
56. Ozkaynak E., Rueger D. C., Drier E. A., Corbett C., Ridge R. J., Sampath T. K., Opperman H. OP-1 cDNA encodes an osteogenic protein in the TGF-β family. EMBO J. 9:1990;2085-2093.
57. Parham P., Bodmer W. F. Monoclonal antibody to a human histocompatibility alloantigen, HLA-A2. Nature (London). 276:1978;397-399.
58. Parham P., Brodsky F. M. Partial purification and some properties of BB7.2. A cytotoxic monoclonal antibody with specificity for HLA-A2 and a variant of HLA-A28. Hum. Immunol. 3:1981;277-299.
59. Perucho M., Hanahan D., Wigler M. Genetic and physical linkage of exogenous sequences in transformed cells. Cell. 22:1980;309-317.
60. Prehn R. T., Main J. M. Immunity to methylcholanthrene-induced sarcomas. J. Natl. Cancer Inst. 18:1957;769-778.
61. Rötzschke O., Falk K., Deres K., Schild H., Norda M., Metzger J., Jung G., Rammensee H.-G. Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells. Nature. 348:1990;252-254.
62. Salter R. D., Howell D. N., Cresswell P. Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids. Immunogenetics. 21:1985;235-246.
63. Sambrook J., Fritsch E. F., Maniatis T. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
64. Seed B. An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2. Nature. 329:1987;840-842.
65. Seed B., Aruffo A. Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure. Proc. Natl. Acad. Sci. USA. 84:1987;3365-3369.
66. Simmons D. L., Satterthwaite A. B., Tenen D. G., Seed B. Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells. J. Immunol. 148:1992;267-271.
67. -. EMBO J. 9:1990;1041-1050.
68. Townsend A., Rothbard J., Gotch F., Bahadur G., Wraith D., McMichael A. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell. 44:1986;959-968.
69. Traversari C., van der Bruggen P., van den Eynde B., Hainaut P., Lemoine C., Ohta N., Old L., Boon T. Transfection and expression of a gene coding for a human melanoma antigen recognized by autologous cytolytic T lymphocytes. Immunogenetics. 35:1992a;145-152.
70. Traversari C., van der Bruggen P., Luescher I. F., Lurquin C., Chomez P., Van Pel A., De Plaen E., Amar-Costesec A., Boon T. A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E. J. Exp. Med. 176:1992b;1453-1457.
71. Uyttenhove C., Maryanski J. L., Boon T. Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression. J. Exp. Med. 157:1983;1040-1052.
72. Van den Eynde B., Hainaut P., Hérin M., Knuth A., Lemoine C., Weynants P., van der Bruggen P., Fauchet R., Boon T. Presence on a human melanoma of multiple antigens recognized by autologous CTL. Int. J. Cancer. 44:1989;634-640.
73. Van den Eynde B., Lethé B., Van Pel A., De Plaen E., Boon T. The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice. J. Exp. Med. 173:1991;1373-1384.
74. Van den Eynde B., Peeters O., De Backer O., Gaugler B., Lucas S., Boon T. A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma. J. Exp. Med. 182:1995;689-698.
75. van der Bruggen P., Szikora J.-P., Boël P., Wildmann C., Somville M., Sensi M., Boon T. Autologous cytolytic T lymphocytes recognize a MAGE-1 nonapeptide on melanomas expressing HLA-Cw*1601. Eur. J. Immunol. 24:1994;2134-2140.
76. van der Bruggen P., Traversari C., Chomez P., Lurquin C., De Plaen E., Van den Eynde B., Knuth A., Boon T. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science. 254:1991;1643-1647.
77. Van Pel A., De Plaen E., Boon T. Selection of a highly transfectable variant from mouse mastocytoma P815. Somat. Cell Genet. 11:1985;467-475.
78. Van Pel A., Vessière F., Boon T. Protection against two spontaneous mouse leukemias conferred by immunogenic variants obtained by mutagenesis. J. Exp. Med. 157:1983;1992-2001.
79. Viret C., Davodeau F., Guilloux Y., Bignon J.-D., Semana G., Breathnach R., Jotereau F. Recognition of shared melanoma antigen by HLA-A2-restricted cytolytic T cell clones derived from human tumor-infiltrating lymphocytes. Eur. J. Immunol. 23:1993;141-146.
80. Weynants P., Lethé B., Brasseur F., Marchand M., Boon T. Expression of MAGE genes by non-small-cell lung carcinomas. Int. J. Cancer. 56:1994;826-829.
81. Wölfel T., Hauer M., Klehmann E., Brichard V., Ackermann B., Knuth A., Boon T., Meyer zum Büschenfelde K.-H. Analysis of antigens recognized on human melanoma cells by A2-restricted cytolytic T lymphocytes (CTL). Int. J. Cancer. 55:1993;237-244.
82. Wölfel T., Klehmann E., Müller C., Schütt K.-H., Meyer zum Büschenfelde K.-H., Knuth A. Lysis of human melanoma cells by autologous cytolytic T cell clones. Identification of human histocompatibility leukocyte antigen A2 as a restriction element for three different antigens. J. Exp. Med. 170:1989;797-810.
83. Wölfel T., Van Pel A., Brichard V., Schneider J., Seliger B., Meyer zum Büschenfelde K.-H., Boon T. Two tyrosinase nonapeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes. Eur. J. Immunol. 24:1994;759-764.
84. Wölfel T., Van Pel A., De Plaen E., Lurquin C., Maryanski J. L., Boon T. Immunogenic (tum-) variants obtained by mutagenesis of mouse mastocytoma P815. VIII. Detection of stable transfectants expressing a tum- antigen with a cytolytic T cell stimulation assay. Immunogenetics. 26:1987;178-187.
85. Yang S. Y., Morishima Y., Collins N. H., Alton T., Pollack M. S., Yunis E. J., Dupont B. Comparison of one-dimensional IEF patterns for serologically detectable HLA-A and B allotypes. Immunogenetics. 19:1984;217-231.