Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis

Journal of Molecular Biology

Volumn 305, Issue 3, 2001, Pages 389-399

  You, Young Hyun ^a   Pfeifer, Gerd P ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

P53; Skin cancer; Sunlight; Transgenic mutation assays; UV

Indexed keywords

5 METHYLCYTOSINE; CYCLOBUTANE; PROTEIN P53; PYRIMIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CPG ISLAND; DIMERIZATION; METHYLATION; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SKIN CANCER; SKIN CARCINOGENESIS; SUNLIGHT; TRANSGENE; ULTRAVIOLET C RADIATION; ULTRAVIOLET RADIATION;

EID: 0035910281     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4322     Document Type: Article

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