Transforming Growth Factor-β Receptor-associated Protein 1 Is a Smad4 Chaperone

Journal of Biological Chemistry

Volumn 276, Issue 22, 2001, Pages 19495-19502

  Wurthner, Jens U ^a   Frank, David B ^a   Felici, Angelina ^a   Green, Harry M ^a   Cao, Zhouhong ^a   Schneider, Michael D ^b   McNally, James G ^a   Lechleider, Robert J ^c   Roberts, Anita B ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; SIGNALING;

VICINITY;

PROTEINS;

ACTIVIN RECEPTOR; CHAPERONE; CYTOPLASM PROTEIN; PROTEIN; PROTEIN SERINE THREONINE KINASE; SMAD PROTEIN; SMAD2 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR ASSOCIATED PROTEIN 1; UNCLASSIFIED DRUG; ACTIVIN; CARRIER PROTEIN; DNA BINDING PROTEIN; EPITOPE; GREEN FLUORESCENT PROTEIN; INHIBIN; LIGAND; PHOTOPROTEIN; SIGNAL PEPTIDE; SMAD2 PROTEIN, HUMAN; SMAD2 PROTEIN, MOUSE; SMAD4 PROTEIN, HUMAN; SMAD4 PROTEIN, MOUSE; TGFBRAP1 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; COMPLEX FORMATION; CONTROLLED STUDY; GENE DELETION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CELL STRAIN COS1; CYTOPLASM; FLUORESCENCE MICROSCOPY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; IMMUNOBLOTTING; METABOLISM; MOUSE; PLASMID; PROTEIN BINDING; PROTEIN SYNTHESIS; PROTEIN TERTIARY STRUCTURE; REPORTER GENE; SERODIAGNOSIS;

ANIMALIA;

ACTIVINS; ANIMALS; CARRIER PROTEINS; CELL LINE; COS CELLS; CYTOPLASM; DNA-BINDING PROTEINS; EPITOPES; GENE DELETION; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOBLOTTING; INHIBINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; LUMINESCENT PROTEINS; MICE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MOLECULAR CHAPERONES; PLASMIDS; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD4 PROTEIN; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 0035379649     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006473200     Document Type: Article

References (40)

1. Roberts, A. B., and Sporn, M. B. (1990) in Handbook of Experimental Pharmacology. Peptide Growth Factors and Their Receptors (Sporn, M. B., and Roberts, A. B., eds) pp. 419-472, Springer-Verlag, Berlin
2. Massague, J., and Chen, Y. G. (2000) Genes Dev. 14, 627-644
3. Wrana, J. L., Tran, H., Attisano, L., Arora, K., Childs, S. R., Massague, J., and O'Connor, M. B. (1994) Mol. Cell. Biol. 14, 944-950
4. ten Dijke, I., Miyazono, I., and Heldin, I. (2000) Trends Biochem. Sci 25, 64-70
5. Liu, X., Sun, Y., Constantinescu, S. N., Karam, E., Weinberg, R. A., and Lodish, H. F. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 10669-10674
6. Yingling, J. M., Datto, M. B., Wong, C., Frederick, J. P., Liberati, N. T., and Wang, X. F. (1997) Mol. Cell. Biol. 17, 7019-7028
7. Ulloa, L., Doody, J., and Massague, J. (1999) Nature 397, 710-713
8. Kretzschmar, M., Doody, J., and Massague, J. (1997) Nature 389, 618-622
9. de Caestecker, M. P., Parks, W. T., Frank, C. J., Castagnino, P., Bottaro, D. P., Roberts, A. B., and Lechleider, R. J. (1998) Genes Dev. 12, 1587-1592
10. Engel, M. E., McDonnell, M. A., Law, B. K., and Moses, H. L. (1999) J. Biol. Chem. 274, 37413-37420
11. Yanagisawa, J., Yanagi, Y., Masuhiro, Y., Suzawa, M., Watanabe, M., Kashiwagi, K., Toriyabe, T., Kawabata, M., Miyazono, K., and Kato, S. (1999) Science 283, 1317-1321
12. Song, C. Z., Tian, X., and Gelehrter, T. D. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 11776-11781
13. Nishita, M., Hashimoto, M. K., Ogata, S., Laurent, M. N., Ueno, N., Shibuya, H., and Cho, K. W. (2000) Nature 403, 781-785
14. Tsukazaki, T., Chiang, T. A., Davison, A. F., Attisano, L., and Wrana, J. L. (1998) Cell 95, 779-791
15. Datta, P. K., Chytil, A., Gorska, A. E., and Moses, H. L. (1998) J. Biol. Chem. 273, 34671-34674
16. Wang, T., Li, B. Y., Danielson, P. D., Shah, P. C., Rockwell, S., Lechleider, R. J., Martin, J., Manganaro, T., and Donahoe, P. K. (1996) Cell 86, 435-444
17. Kawabata, M., Imamura, T., Miyazono, K., Engel, M. E., and Moses, H. L. (1995) J. Biol. Chem. 270, 29828-29831
18. Chen, R. H., Miettinen, P. J., Maruoka, E. M., Choy, L., and Derynck, R. (1995) Nature 377, 548-552
19. Griswold-Prenner, I., Kamibayashi, C., Maruoka, E. M., Mumby, M. C., and Derynck, R. (1998) Mol. Cell. Biol. 18, 6595-6604
20. Chen, Y. G., Liu, F., and Massague, J. (1997) EMBO J. 16, 3866-3876
21. Shou, W., Aghdasi, B., Armstrong, D. L., Guo, Q., Bao, S., Charng, M. J., Mathews, L. M., Schneider, M. D., Hamilton, S. L., and Matzuk, M. M. (1998) Nature 391, 489-492
22. Choy, L., and Derynck, R. (1998) J. Biol. Chem. 273, 31455-31462
23. Charng, M. J., Zhang, D., Kinnunen, P., and Schneider, M. D. (1998) J. Biol. Chem. 273, 9365-9368
24. Pastorcic, M., and Sarkar, D. K. (1997) Cytokine 9, 106-111
25. Gilboa, L., Wells, R. G., Lodish, H. F., and Henis, Y. I. (1998) J. Cell Biol. 140, 767-777
26. Henis, Y. I., Moustakas, A., Lin, H. Y., and Lodish, H. F. (1994) J. Cell Biol. 126, 139-154
27. Wrana, J. L., and Attisano, L. (2000) Cytokine Growth Factor Rev. 11, 5-13
28. Wrana, J. L., Attisano, L. C., Arcamo, J., Zentella, A., Doody, J., Laiho, M., Wang, X. F., and Massague, J. (1992) Cell 71, 1003-1014
29. Zawel, L., Dai, J. L., Buckhaults, P., Zhou, S., Kinzler, K. W., Vogelstein, B., and Kern, S. E. (1998) Mol. Cell 1, 611-617
30. Macias-Silva, M., Abdollah, S., Hoodless, P. A., Pirone, R., Attisano, L., and Wrana, J. L. (1996) Cell 87, 1215-1224
31. Zhang, Y., Feng, X., We, R., and Derynck, R. (1996) Nature 383, 168-172
32. Bukau, B., and Horwich, A. L. (1998) Cell 92, 351-366
33. Lo, R. S., Chen, Y. G., Shi, Y., Pavletich, N. P., and Massague, J. (1998) EMBO J. 17, 996-1005
34. Souchelnytskyi, S., Tamaki, K., Engstrom, U., Wernstedt, C., ten Dijke, P., and Heldin, C. H. (1997) J. Biol. Chem. 272, 28107-28115
35. Bu, G., and Schwartz, A. L. (1998) Trends Cell Biol. 8, 272-276
36. Shoji, H., Tsuchida, K., Kishi, H., Yamakawa, N., Matsuzaki, T., Liu, Z., Nakamura, T., and Sugino, H. (2000) J. Biol. Chem. 275, 5485-5492
37. Provost, P., Samuelsson, B., and Radmark, O. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1881-1885
38. Nakamura, N., Herata, A., Ohsumi, Y., and Wada, Y. (1997) J. Biol. Chem. 272, 11344-11349
39. Nagase, T., Kikuno, R., Ishikawa, K., Hirosawa, M., and Ohara, O. (2000) DNA Res. 7, 143-150
40. Razani, B., Zhang, X. L., Bitzer, M., von Gersdorff, G., Bottinger, E. P., and Lisanti, M. P. (2001) J. Biol. Chem. 276, 6727-6738