Antagonism of CRF2 receptors produces anxiolytic behavior in animal models of anxiety

Brain Research

Volumn 902, Issue 2, 2001, Pages 135-142

  Takahashi, Lorey K ^a,b   Ho, Siew Peng ^b   Livanov, Valentin ^b   Graciani, Nilsa ^b   Arneric, Stephen P ^b  

^a UNIVERSITY OF HAWAII   (United States)

^b DUPONT COMPANY   (United States)

Author keywords

Animal anxiety model; Anxiety; Anxiolytic behavior; Corticotropin releasing factor (CRF) receptor; CRF2 antagonist; Stress

Indexed keywords

ANTISAUVAGINE 30; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BEHAVIOR; CONDITIONED REFLEX; CONTROLLED STUDY; DEFENSIVE BEHAVIOR; DOSE RESPONSE; DRUG ANTAGONISM; EXPLORATORY BEHAVIOR; FREEZING; LOCOMOTION; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; TRANQUILIZING ACTIVITY; WITHDRAWAL REFLEX;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BRAIN; CONDITIONING (PSYCHOLOGY); CORTICOTROPIN-RELEASING HORMONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEAR; MALE; MAZE LEARNING; MOTOR ACTIVITY; NEURONS; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; STRESS;

EID: 0035369011     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02405-2     Document Type: Article

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