Vitamin D receptor and nuclear receptor coactivators: Crucial interactions in vitamin D-mediated transcription

Steroids

Volumn 66, Issue 3-5, 2001, Pages 171-176

  MacDonald, Paul N ^a   Baudino, Troy A ^a   Tokumaru, Hisashi ^a   Dowd, Diane R ^a   Zhang, Chi ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Coactivators; Nuclear receptor; Steroid hormones; Transcription regulation; Vitamin D receptor

Indexed keywords

CALCITRIOL; CELL NUCLEUS RECEPTOR; CELL NUCLEUS RECEPTOR COACTIVATOR PROTEIN; COACTIVATOR PROTEIN; PROTEIN; PROTEIN NCOA 62; RETINOID X RECEPTOR; STEROID RECEPTOR; STEROID RECEPTOR COACTIVATOR 1; UNCLASSIFIED DRUG; VITAMIN D; VITAMIN D RECEPTOR;

CONFERENCE PAPER; DIMERIZATION; GENETIC TRANSCRIPTION; LIGAND BINDING; NONHUMAN; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN INTERACTION; REVIEW; TRANSCRIPTION REGULATION;

ANIMALS; HUMANS; RECEPTORS, CALCITRIOL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; VITAMIN D;

EID: 0035342666     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(00)00200-2     Document Type: Article

References (44)

1. The vitamin D hormone and its nuclear receptor; molecular actions and disease states
2. The nuclear vitamin D receptor; biological and molecular regulatory properties revealed
3. Transcriptional activation through the vitamin D receptor in osteoblasts [In Process Citation]
4. 1,25-Dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene
5. 3 enhancement of mouse secreted phosphoprotein 1 (Spp-1 or osteopontin) gene expression
6. The vitamin D-responsive element in the human osteocalcin gene
7. 3-response element in the 5′-flanking region of the rat calbindin D-9k gene
8. 3
9. 3- and butyrate-inducible responses
10. Cloning of the promoter for the avian integrin b3 subunit gene and its regulation by 1,25-dihydroxyvitamin D3
11. Nuclear receptor coactivators and corepressors
12. Nuclear receptor coregulators; cellular and molecular biology
13. Molecular cloning and properties of a full-length putative thyroid hormone receptor coactivator
14. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
15. The nuclear hormone receptor coactivator SRC-1 is a specific target of p300
16. Steroid receptor coactivator-1 is a histone acetyltransferase
17. The transcriptional coactivators p300 and CBP are histone acetyltransferases
18. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
19. The CBP co-activator is a histone acetyltransferase
20. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
21. GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors
22. TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors
23. A signature motif in transcriptional co-activators mediates binding to nuclear receptors [see comments]
24. Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C-terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcription factor IIB, in vitro
25. Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α
26. Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid
27. A structural role for hormone in the thyroid hormone receptor
28. A canonical structure for the ligand-binding domain of nuclear receptors [see comments] [published erratum appears in Nat Struct Biol 1996 Feb;3(2):206]
29. Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors
30. Structure and specificity of nuclear receptor-coactivator interactions
31. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
32. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
33. Identification of an autonomous transactivation domain in helix H3 of the vitamin D receptor
34. The autonomous transactivation domain in helix H3 of the vitamin D receptor is required for transactivation and coactivator interaction
35. Lysine 246 of the vitamin D receptor is crucial for ligand-dependent interaction with coactivators and transcriptional activity
36. GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors
37. A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system
38. Convergence of transforming growth factor-β and vitamin D signaling pathways on SMAD transcriptional coactivators
39. Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription
40. The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42
41. The Drosophila nuclear protein Bx42, which is found in many puffs on polytene chromosomes, is highly charged
42. Two puff-specific proteins bind within the 2.5 kb upstream region of the Drosophila melanogaster Sgs-4 gene
43. The homolog of chromatin binding protein Bx42 identified in Dictyostelium