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Volumn 4, Issue 4, 1998, Pages 610-615

Resistance to HIV protease inhibitors

Author keywords

141W94; Drug resistance; Indinavir; Nelfinavir; Ritonavir; Saquinavir

Indexed keywords

ANTIRETROVIRUS AGENT; INDINAVIR; PROTEINASE; PROTEINASE INHIBITOR;

EID: 0031856659     PISSN: 13518216     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2516.1998.440610.x     Document Type: Conference Paper
Times cited : (62)

References (24)
  • 1
    • 0002409052 scopus 로고    scopus 로고
    • Preventing HIV-1 drug resistance
    • Condra JH, Emini EA. Preventing HIV-1 drug resistance. Science & Medicine 1997; 4(1): 14-23.
    • (1997) Science & Medicine , vol.4 , Issue.1 , pp. 14-23
    • Condra, J.H.1    Emini, E.A.2
  • 2
    • 0028943992 scopus 로고
    • In-vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
    • Condra JH, Schleif WA, Blahy OM, et al. In-vivo emergence of HIV-1 variants resistant to multiple protease inhibitors. Nature 1995; 374(6522) :569-71.
    • (1995) Nature , vol.374 , Issue.6522 , pp. 569-571
    • Condra, J.H.1    Schleif, W.A.2    Blahy, O.M.3
  • 3
    • 10344263394 scopus 로고    scopus 로고
    • Genetic correlates of in-vivo viral resistance to indinavir, a human immunodeficiency virus type-1 protease inhibitor
    • Condra JH, Holder DJ, Schleif WA, et al. Genetic correlates of in-vivo viral resistance to indinavir, a human immunodeficiency virus type-1 protease inhibitor. J Virol 1996; 70(12): 8270-6.
    • (1996) J Virol , vol.70 , Issue.12 , pp. 8270-8276
    • Condra, J.H.1    Holder, D.J.2    Schleif, W.A.3
  • 4
    • 0029731556 scopus 로고    scopus 로고
    • Mutational anatomy of an HIV-1 protease variant conferring cross-resistance to protease inhibitors in clinical-trials - Compensatory modulations of binding and activity
    • Schock HB, Garsky VM, Kuo LC. Mutational anatomy of an HIV-1 protease variant conferring cross-resistance to protease inhibitors in clinical-trials - compensatory modulations of binding and activity. J Biol Chem 1996; 271(50): 31957-63.
    • (1996) J Biol Chem , vol.271 , Issue.50 , pp. 31957-31963
    • Schock, H.B.1    Garsky, V.M.2    Kuo, L.C.3
  • 5
    • 0029926056 scopus 로고    scopus 로고
    • Reduced sensitivity to saquinavir - An update on genotyping from phase I/II trials
    • Jacobsen H, Haenggi M, Ott M, et al. Reduced sensitivity to saquinavir - an update on genotyping from phase I/II trials. Antivir Res 1996; 29(1): 95-7.
    • (1996) Antivir Res , vol.29 , Issue.1 , pp. 95-97
    • Jacobsen, H.1    Haenggi, M.2    Ott, M.3
  • 6
    • 15444377672 scopus 로고    scopus 로고
    • Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
    • Molla A, Korneyeva M, Gao Q, et al. Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. Nature Med 1996; 2(7): 760-6.
    • (1996) Nature Med , vol.2 , Issue.7 , pp. 760-766
    • Molla, A.1    Korneyeva, M.2    Gao, Q.3
  • 7
    • 0030012398 scopus 로고    scopus 로고
    • Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538)
    • Schmit JC, Ruiz L, Clotet B, et al. Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538). AIDS 1996; 10(9): 995-9.
    • (1996) AIDS , vol.10 , Issue.9 , pp. 995-999
    • Schmit, J.C.1    Ruiz, L.2    Clotet, B.3
  • 8
    • 13344275873 scopus 로고    scopus 로고
    • Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human-immunodeficiency-virus protease
    • Patick AK, Markowitz M, Appelt K, et al. Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human-immunodeficiency-virus protease. Antimicrob Agents Chemother 1996; 40(2): 292-7.
    • (1996) Antimicrob Agents Chemother , vol.40 , Issue.2 , pp. 292-297
    • Patick, A.K.1    Markowitz, M.2    Appelt, K.3
  • 9
    • 0343628950 scopus 로고    scopus 로고
    • Genotypic and phenotypic characterization of HIV-1 variants isolated from in vitro selection studies and from patients treated with the protease inhibitor, nelfinavir
    • Patick AK, Duran M, Cao Y, et al. Genotypic and phenotypic characterization of HIV-1 variants isolated from in vitro selection studies and from patients treated with the protease inhibitor, nelfinavir. Antivir Ther 1996; 1 (Suppl 1): 17-8.
    • (1996) Antivir Ther , vol.1 , Issue.1 SUPPL. , pp. 17-18
    • Patick, A.K.1    Duran, M.2    Cao, Y.3
  • 10
    • 0343694819 scopus 로고    scopus 로고
    • Selection for high-level resistance to HIV-1 protease inhibitors used in pairs
    • Smith T, Swanstrom R. Selection for high-level resistance to HIV-1 protease inhibitors used in pairs. Antivir Ther 1996; 1 (Suppl 1): 12-3.
    • (1996) Antivir Ther , vol.1 , Issue.1 SUPPL. , pp. 12-13
    • Smith, T.1    Swanstrom, R.2
  • 11
    • 0029092503 scopus 로고
    • In-vitro selection and characterization of human-immunodeficiency-virus type-1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease
    • Partaledis JA, Yamaguchi K, Tisdale M, et al. In-vitro selection and characterization of human-immunodeficiency-virus type-1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease. J Virol 1995; 69(9): 5228-35.
    • (1995) J Virol , vol.69 , Issue.9 , pp. 5228-5235
    • Partaledis, J.A.1    Yamaguchi, K.2    Tisdale, M.3
  • 12
    • 15844378825 scopus 로고    scopus 로고
    • Extensive polymorphisms observed in HIV-1 clade-b protease gene using high-density oligonucleotide arrays
    • Kozal MJ, Shah N, Shen NP, et al. Extensive polymorphisms observed in HIV-1 clade-b protease gene using high-density oligonucleotide arrays. Nature Med 1996; 2(7): 753-9.
    • (1996) Nature Med , vol.2 , Issue.7 , pp. 753-759
    • Kozal, M.J.1    Shah, N.2    Shen, N.P.3
  • 13
    • 0028952146 scopus 로고
    • HIV Population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
    • Coffin JM. HIV Population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy. Science 1995; 267: 483-9.
    • (1995) Science , vol.267 , pp. 483-489
    • Coffin, J.M.1
  • 14
    • 85030335911 scopus 로고
    • Evidence for the existence of long-lived genetic reservoirs of HIV-1 in infected patients
    • Condra JH, Schleif WA, Blahy OM, et al. Evidence for the existence of long-lived genetic reservoirs of HIV-1 in infected patients. J Acq Immun Def Synd Hum Retrovirol 1995; 10(3): 82.
    • (1995) J Acq Immun Def Synd Hum Retrovirol , vol.10 , Issue.3 , pp. 82
    • Condra, J.H.1    Schleif, W.A.2    Blahy, O.M.3
  • 16
    • 0029806127 scopus 로고    scopus 로고
    • Rational approaches to resistance - Using saquinavir
    • Boucher C. Rational approaches to resistance - using saquinavir. AIDS 1996; 10(1): S15-S19.
    • (1996) AIDS , vol.10 , Issue.1
    • Boucher, C.1
  • 17
    • 0029133978 scopus 로고
    • Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors
    • Tisdale M, Myers RE, Maschera B, Parry N, Oliver NM, Blair ED. Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors. Antimicrob Agents Chemother 1995; 39(8): 1704-10.
    • (1995) Antimicrob Agents Chemother , vol.39 , Issue.8 , pp. 1704-1710
    • Tisdale, M.1    Myers, R.E.2    Maschera, B.3    Parry, N.4    Oliver, N.M.5    Blair, E.D.6
  • 20
    • 0030849517 scopus 로고    scopus 로고
    • Clinically effective HIV-1 protease inhibitors
    • Vacca JP, Condra JH. Clinically effective HIV-1 protease inhibitors. Drug Discov Today 1997; 2(7): 261-72.
    • (1997) Drug Discov Today , vol.2 , Issue.7 , pp. 261-272
    • Vacca, J.P.1    Condra, J.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.