Inhibition of angiogenesis in vivo by ets-1 antisense oligonucleotides - Inhibition of ets-1 transcription factor expression by the antibiotic fumagillin

Angewandte Chemie - International Edition

Volumn 38, Issue 21, 1999, Pages 3228-3231

  Wernert, Nicolas ^a   Stanjek, Antje ^b   Kiriakidis, Serafim ^c   Hügel, Anja ^a   Jha, Hem Chandra ^c   Mazitschek, Ralph ^b   Giannis, Athanassios ^b  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF KARLSRUHE   (Germany)

^c NONE

Author keywords

Angiogenesis; Antibiotics; Antisense agents; Tumor therapy

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; FUMAGILLIN; TRANSCRIPTION FACTOR; TYROSINE KINASE RECEPTOR; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CHORIOALLANTOIS; ENZYME ACTIVITY; METASTASIS; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR BINDING; TUMOR GROWTH;

EID: 0033517802     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19991102)38:21<3228::AID-ANIE3228>3.0.CO;2-8     Document Type: Article

References (41)

1. J. Folkman, H. Brehm in Inflammation: Basic Principles and Clinical Correlates (Eds.: J. I. Gallin, I. M. Goldstein, R. Snyderman), 2nd ed., Ranen, New York, 1992, pp. 821-839.
2. J. Folkman, New Engl. J. Med. 1971, 285, 1182-1186.
3. a) J. Folkman, Nat. Med. 1995, 1, 27-31;
4. b) J. Folkman, New Engl. J. Med. 1995, 333, 1757-1763.
5. S. Brehm, Angiogenesis 1998, 2, 9-20.
6. A. Giannis, F. Rübsam, Angew. Chem. 1997, 109, 606-609; Angew. Chem. Int. Ed. Engl. 1997, 36, 588-590.
7. A. Giannis, F. Rübsam, Angew. Chem. 1997, 109, 606-609; Angew. Chem. Int. Ed. Engl. 1997, 36, 588-590.
8. W. Risau, Nature 1997, 386, 671-674.
9. R. Haubner, D. Finsinger, H. Kessler, Angew. Chem. 1997, 109, 1440-1456; Angew. Chem. Int. Ed. Engl. 1997, 36, 1374-1389.
10. R. Haubner, D. Finsinger, H. Kessler, Angew. Chem. 1997, 109, 1440- 1456; Angew. Chem. Int. Ed. Engl. 1997, 36, 1374-1389.
11. H. P. Hammes, M. Brownlee, A. Jonczyk, A. Sutter, K. T. Preissner, Nat. Med. 1996, 2, 529-533.
12. C. M. Storgard, D. G. Stupack, A. Jonczyk, S. L. Goodman, R. I. Fox, D. A. Cheresh, J. Clin. Invest. 1999, 103, 47-54.
13. a) J. Folkman, Y. Shing, J. Biol. Chem. 1992, 267, 10931-10934;
14. b) L. K. Shawver, K. E. Lipson, T. A. T. Fong, G. McMahon, G. D. Plowman, L. M. Strawn, Drug Discov. Today 1997, 2, 50-63; H. A. Augustin, Trends Pharm. Sci. 1998, 19, 216-222.
15. b) L. K. Shawver, K. E. Lipson, T. A. T. Fong, G. McMahon, G. D. Plowman, L. M. Strawn, Drug Discov. Today 1997, 2, 50-63; H. A. Augustin, Trends Pharm. Sci. 1998, 19, 216-222.
16. G. Neufeld, T. Cohen, S. Gengrinovitch, Z. Poltorak, FASEB J. 1999, 13, 9-22.
17. D. Hanahan, Science 1997, 277, 48-50.
18. J. Dittmer, A. Nordheim, Biochim. Biophys. Acta 1998, 1377, F1-F11.
19. N. Wernert, Virchows Arch. 1997, 430, 433-443.
20. N. Wernert, M. B. Raes, P. Lassalle, M. P. Dehouck, B. Gosselin, B. Vandenburger, D. Stehelin, Am. J. Pathol. 1992, 140, 119-127.
21. N. Wernert, F. Gilles, V. Fafeur, F. Bouali, M. B. Raes, C. Pyke, T. Dupressoir, G. Seitz, B. Vandenburger, D. Stehelin, Cancer Res. 1994, 54, 5683-5688.
22. C. Iwasaka, K. Tanaka, M. Abe, Y. Sato, J. Cell Physiol. 1996, 169, 522-531.
23. K. Wakiya, A. Begue, D. Stehelin, M. Shibuya, J. Biol. Chem. 1996, 271, 30823-30828.
24. R. Crum, S. Szabo, J. Folkman, Science 1985, 230, 1375-1378.
25. P. Noguiez-Hellin, M. R. Le Meur, J. L. Salzmann, D. Klatzmann, Proc. Natl. Acad. Sci. USA 1996, 93, 4175-4180.
26. I. Bolon, V. Gouyer, M. Devouassoux, B. Vandenbunder, N. Wernert, D. Moro, C. Brambilla, E. Brambilla, Am. J. Pathol. 1995, 147, 1298-1310.
27. R. Bicknell, C. E. Lewis, N. Ferrara, Tumour Angiogenesis, Oxford University Press, Oxford, 1997.
28. D. R. Edwards, G. Murphy, Nature 1998, 394, 527-528.
29. D. Ingber, T. Fujita, S. Kishimoto, K. Sudo, T. Kanamaru, H. Brehm, J. Folkman, Nature 1990, 348, 555-557.
30. The p51-Ets-1 protein is the full-length c-ets-1 transcript, while the p39-Ets-1 protein is a splice-variant lacking the exon VII; see R. J. Fisher, S. Koizumi, A. Kondoh, J. M. Mariano, G. Mavrothalassitis, N. K. Bhat, T. S. Papas, J. Biol. Chem. 1992, 267, 17 957-17 965.
31. Treatment of metastatic cervical cancer with TNP-470 in a 49-year-old patient resulted in complete remission, a rare event in this condition: A. P. Kudelka, C. F. Versraegen, E. Loyer, New Engl. J. Med. 1998, 338, 991-992.
32. a) N. Sin, L. Meng, M. Q. W. Wang, J. J. Wen, W. G. Bornmann, C. M. Crews, Proc. Natl. Acad. Sci. USA 1997, 94, 6099-6103;
33. b) E. C. Griffith, Z. Su, B. E. Turk, S. P. Chen, Y. H. Chang, Z. C. Wu, K. Biemann, J. O. Liu, Chem. Biol. 1997, 4, 461-471;
34. c) E. C. Griffith, Z. Su, S. Niwayama, C. A. Ramsey, Y.-H. Chang, J. O. Liu, Proc. Natl. Acad. Sci. USA 1998, 95, 15183-15188.
35. S. Liu, J. Widom, C. W. Kemp, C. M. Crews, J. Clardy, Science 1998, 282, 1324-1327.
36. R. A. Bradshow, W. W. Brickey, K. W. Walker, Trends Biochem. Sci. 1998, 23, 263-267.
37. J. Taunton, Chem. Biol. 1997, 4, 493-496.
38. L. F. Fleischman, A. M. Pilaro, K. Murakami, A. Kondoh, R. J. Fischer, T. S. Papas, Oncogene 1993, 8, 771-780.
39. D. K. Watson, M. J. McWillis, P. Lapis, J. A. Lautenberger, C. W. Schweifest, T. S. Papas, Proc. Natl. Acad. Sci. USA 1988, 85, 7862-7866.
40. R. K. Jain, K. Schlenger, M. Höckel, F. Yuan, Nat. Med. 1997, 3, 1203-1208.
41. P. Chomczynski, Biotechniques 1993, 15, 532-534.