-
1
-
-
0030426902
-
Pharmacological profile of SB203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function
-
(1996)
J Pharmacol Exp Ther
, vol.279
, pp. 1453-1461
-
-
Badger, A.M.1
Bradbeer, J.N.2
Votta, B.3
Lee, J.C.4
Adams, J.L.5
Griswold, D.E.6
-
2
-
-
0026560942
-
Hypothesis on the pathogenesis and natural history of Helicobacter pylori-induced inflammation
-
(1992)
Gastroenterology
, vol.102
, pp. 720-727
-
-
Blaser, M.J.1
-
4
-
-
0031691768
-
Role of cytokines in pathogenesis of Helicobacter pylori-induced mucosal damage
-
(1998)
Dig Dis Sci
, vol.43
-
-
Crabtree, J.E.1
-
5
-
-
0028032159
-
Interleukin-8 expression in Helicobacter pylori infected, normal, and neoplastic gastroduodenal mucosa
-
(1994)
J Clin Pathol
, vol.47
, pp. 61-66
-
-
Crabtree, J.E.1
Wyatt, J.I.2
Trejdosiewicz, L.K.3
Peichl, P.4
Nichols, P.H.5
Ramsay, N.6
Primrose, J.N.7
Lindley, I.J.8
-
6
-
-
0028814039
-
Expression of interleukin-8 and CD54 by human gastric epithelium after Helicobacter pylori infection in vitro
-
(1995)
Gastroenterology
, vol.108
, pp. 65-74
-
-
Crowe, S.A.1
Alvarez, L.2
Dytoc, M.3
Hunt, R.H.4
Muller, M.5
Sherman, P.6
Patel, J.7
Jin, Y.8
Ernst, P.B.9
-
7
-
-
0028988138
-
SB203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
-
(1995)
FEBS Lett
, vol.364
, pp. 229-233
-
-
Cuenda, A.1
Rouse, J.2
Doza, Y.N.3
Meier, R.4
Cohen, P.5
Gallagher, T.F.6
Young, P.R.7
Lee, J.C.8
-
8
-
-
0030819108
-
Potencies of leflunomide and HR325 as inhibitors of prostaglandin endoperoxide H synthase-1 and -2: Comparison with nonsteroidal anti-inflammatory drugs
-
(1997)
J Pharmacol Exp Ther
, vol.282
, pp. 339-347
-
-
Curnock, A.P.1
Robson, P.A.2
Yea, C.M.3
Moss, D.4
Gadher, S.5
Thomson, T.A.6
Westwood, R.7
Ruuth, E.8
Williamson, R.A.9
-
11
-
-
0032578559
-
The activation state of p38 MAPK determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding
-
(1998)
Biochemistry
, vol.37
, pp. 13846-13853
-
-
Frantz, B.1
Klatt, T.2
Pang, M.3
Parsons, J.4
Rolando, A.5
Williams, H.6
Tocci, M.J.7
O'Keefe, S.J.8
O'Neill, E.A.9
-
14
-
-
10744227768
-
Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB203580, by alteration of one or more amino acids within the ATP binding pocket
-
(1998)
J Biol Chem
, vol.273
, pp. 15605-15610
-
-
Gum, R.J.1
McLaughlin, M.M.2
Kumar, S.3
Wang, Z.4
Bower, M.J.5
Lee, J.C.6
Adams, J.L.7
Livi, G.P.8
Goldsmith, E.J.9
Young, P.R.10
-
16
-
-
0031934170
-
Pharmacological effects of SB220025, a selective inhibitor of P38 mitogen-activated protein kinase, in angiogenesis and chronic inflammatory disease models
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 687-692
-
-
Jackson, J.R.1
Bolognese, B.2
Hillegass, L.3
Kassis, S.4
Adams, J.5
Griswold, D.E.6
Winkler, J.D.7
-
19
-
-
0032926258
-
Comparison of suppressive effects of a new anti-inflammatory compound, FR167653, on production of PGE2 and inflammatory cytokines, human monocytes, and alveolar macrophages in response to endotoxin
-
(1999)
J Leukoc Biol
, vol.65
, pp. 80-86
-
-
Kawano, T.1
Ogushi, F.2
Tani, K.3
Endo, T.4
Ohmoto, Y.5
Hayashi, Y.6
Sane, S.7
-
25
-
-
0027761036
-
Bicyciic imidazoles as a novel class of cytokine biosynthesis inhibitors
-
(1993)
Ann NY Acad Sci
, vol.696
, pp. 149-170
-
-
Lee, J.C.1
Badger, A.M.2
Griswold, D.E.3
Dunnington, D.4
Truneh, A.5
Votta, B.6
White, J.R.7
Young, P.R.8
Bender, P.E.9
-
26
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
(1994)
Nature (Lond)
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
Strickler, J.E.11
McLaughlin, M.M.12
Siemens, I.R.13
Fisher, S.M.14
Livi, G.P.15
White, J.R.16
Adams, J.L.17
Young, P.R.18
-
33
-
-
0030050987
-
Infiltration of neutrophils by intrapleural injection of tumor necrosis factor, interleukin-1, and interleukin-8 in rats, its modification by actinomycin D
-
(1996)
Br J Pharmacol
, vol.117
, pp. 611-614
-
-
Utsunomiya, I.1
Ito, M.2
Watanabe, K.3
Tsurufuji, S.4
Matsushima, K.5
Oh-ishi, S.6
-
34
-
-
0032745423
-
RWJ67657, a potent, orally active inhibitor of p36 mitogen-activated protein kinase
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 680-687
-
-
Wadsworth, S.A.1
Cavender, D.E.2
Beers, S.A.3
Lalan, P.4
Schafer, P.H.5
Malloy, E.A.6
Wu, W.7
Fahmy, B.8
Olini, G.C.9
Davis, J.E.10
Pellegrino-Gensey, J.L.11
Wachter, M.P.12
Siekierka, J.J.13
-
37
-
-
0030961386
-
FR167653, a dual inhibitor of interleukin-1 and tumor necrosis factor-α, ameliorates endotoxin-induced shock
-
(1997)
Eur J Pharmacol
, vol.327
, pp. 169-175
-
-
Yamamoto, N.1
Sakai, F.2
Yamazaki, H.3
Sato, N.4
Nakahara, K.5
Okuhara, M.6
-
40
-
-
0032519736
-
p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-α or FMLP stimulation
-
(1998)
J Immunol
, vol.160
, pp. 1982-1989
-
-
Zu, Y.-L.1
Qi, J.2
Gilchrist, A.3
Fernandez, G.A.4
Vazquez-Abad, D.5
Kreutzer, D.L.6
Huang, C.-K.7
Sha'afi, R.I.8
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