The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding

Biochemistry

Volumn 37, Issue 39, 1998, Pages 13846-13853

  Frantz, Betsy ^a   Klatt, Tracey ^a   Pang, Margaret ^a   Parsons, Janey ^a   Rolando, Anna ^a   Williams, Hollis ^a   Tocci, Michael J ^a   O'Keefe, Stephen J ^a   O'Neill, Edward A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; PYRIDINE DERIVATIVE;

ARTICLE; DROSOPHILA; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOREGULATION; INFLAMMATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; BINDING, COMPETITIVE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; ENZYME ACTIVATION; HUMANS; IMIDAZOLES; KINETICS; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; RADIOLIGAND ASSAY; RECOMBINANT PROTEINS;

EID: 0032578559     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980832y     Document Type: Article

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