Effect of FR167653, a cytokine suppressive agent, on endotoxin-induced disseminated intravascular coagulation

European Journal of Pharmacology

Volumn 314, Issue 1-2, 1996, Pages 137-142

  Yamamoto, Nobuchika ^a   Sakai, Fumihiko ^a   Yamazaki, Harumi ^a   Nakahara, Kunio ^a   Okuhara, Masakuni ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

disseminated intravascular coagulation; interleukin 1; lipopolysaccharide; TNF (tumor necrosis factor )

Indexed keywords

1 [7 (4 FLUOROPHENYL) 1,2,3,4 TETRAHYDRO 8 (4 PYRIDYL)PYRAZOLO[5,1 C][1,2,4]TRIAZIN 2 YL] 2 PHENYLETHANEDIONE; CYTOKINE; CYTOKINE PRODUCTION INHIBITOR; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING; BLOOD LEVEL; CELL STRAIN 3T3; CELL STRAIN L 929; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; LEUKOPENIA; LYMPHOCYTE; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; RAT; THROMBOCYTOPENIA;

ANIMALS; CELLS, CULTURED; CYTOKINES; DISSEMINATED INTRAVASCULAR COAGULATION; FIBROBLASTS; HUMANS; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MALE; MICE; PYRAZOLES; PYRIDINES; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030600504     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00537-7     Document Type: Article

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