Influence of FR 167653, an inhibitor of TNF-α and IL-1, on the cardiovascular responses to chronic infusion of lipopolysaccharide in conscious rats

Journal of Cardiovascular Pharmacology

Volumn 34, Issue 1, 1999, Pages 64-69

  Gardiner, S M ^a   Kemp, P A ^a   March, J E ^a   Bennett, T ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Cytokines; FR 167653; Haemodynamics; Lipopolysaccharide

Indexed keywords

1 [7 (4 FLUOROPHENYL) 1,2,3,4 TETRAHYDRO 8 (4 PYRIDYL)PYRAZOLO[5,1 C][1,2,4]TRIAZIN 2 YL] 2 PHENYLETHANEDIONE; 1 [7 (4 FLUOROPHENYL) 1,2,3,4 TETRAHYDRO 8 (4 PYRIDYL)PYRAZOLO[5,1C][1,2,4]TRIAZIN 2 YL] 2 PHENYL ETHANE DIONE SULFATE MONOHYDRATE; CREATINE KINASE; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; POTASSIUM; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; HEART FUNCTION; HEMODYNAMICS; KIDNEY DISEASE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASOCONSTRICTION;

ANIMALS; BLOOD PRESSURE; CREATINE KINASE; DRUG INTERACTIONS; HEMODYNAMIC PROCESSES; HINDLIMB; INTERLEUKIN-1; KIDNEY; KIDNEY FUNCTION TESTS; L-LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDES; LIVER; MALE; POTASSIUM; PYRAZOLES; PYRIDINES; RATS; RATS, LONG-EVANS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS;

EID: 0032985948     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199907000-00011     Document Type: Article

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