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Volumn 10, Issue 1-2, 2001, Pages 43-52

Ubiquitin proteasome pathway: Implications and advances in cancer therapy

Author keywords

Apoptosis; Chemoresistance; NF B; p21; p27; p53

Indexed keywords

ACETYLLEUCYLLEUCYLNORLEUCINAL; ALDEHYDE DERIVATIVE; ANGIOGENESIS INHIBITOR; BENZYLOXYCARBONYLISOLEUCYL O TERT BUTYLGLUTAMYLALANYLLEUCINAL; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BENZYLOXYCARBONYLLEUCYLLEUCYLNORVALINAL; BORONIC ACID DERIVATIVE; BORTEZOMIB; CELL CYCLE PROTEIN; CISPLATIN; CVT 634; CYCLIN A; CYCLIN B; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; ETOPOSIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IRINOTECAN; LACTACYSTIN; MG 115; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN BCL 2; PROTEIN P27; PROTEIN P53; PS 273; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TUMOR PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 0035180374     PISSN: 09607404     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-7404(01)00018-4     Document Type: Article
Times cited : (43)

References (100)
  • 7
    • 0028018268 scopus 로고
    • The Ubiquitin-proteasome proteolytic pathway
    • (1994) Cell , vol.79 , pp. 13-21
    • Ciechanover, A.1
  • 9
    • 0025123346 scopus 로고
    • The multicatalytic proteinase complex, a major extralysosomal proteolytic system
    • (1990) Biochemistry , vol.29 , pp. 10289-10297
    • Orlowski, M.1
  • 10
    • 0027410433 scopus 로고
    • Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids
    • (1993) Biochemistry , vol.32 , pp. 1563-1572
    • Orlowski, M.1    Cardoza, C.2    Michaud, C.3
  • 13
    • 0030613646 scopus 로고    scopus 로고
    • Catalysis by a multiprotein IkappaB kinase complex
    • (1997) Science , vol.278 , pp. 818-819
    • Maniatis, T.1
  • 19
    • 0022550756 scopus 로고    scopus 로고
    • α-aminoboronic acid derivatives: Effective inhibitors of aminopeptdiases
    • (1996) Biochemistry , vol.25 , pp. 1286-1291
    • Shenvi, A.1
  • 34
    • 0034039040 scopus 로고    scopus 로고
    • Dial 9-1-1 for p-53: Mechanisms of p53 activation by cellular stress
    • (2000) Neoplasia , vol.2 , pp. 208-225
    • Ljungman, M.1
  • 40
    • 0032429122 scopus 로고    scopus 로고
    • Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts
    • (1998) Cell Death and Differentiation , vol.5 , pp. 1062-1075
    • An, B.1    Goldfarb, R.2    Siman, R.3    Dou, P.4
  • 42
    • 0026545073 scopus 로고
    • Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells
    • (1992) Journal of Cell Biology , vol.117 , pp. 213-224
    • Gallant, P.1    Nigg, E.A.2
  • 52
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1-cyclin-CDK protein kinase activity, is related to p21
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima1    Hunter, T.2
  • 84
    • 0028025563 scopus 로고
    • Apoptosis in cancer therapy: Crossing the threshold
    • (1994) Cell , vol.78 , pp. 539-542
    • Fisher, D.E.1
  • 95
    • 0024281372 scopus 로고
    • Cell and environment interactions in tumor microregions: The multicell spheroid model
    • (1988) Science , vol.240 , pp. 177-184
    • Sutherland, R.M.1
  • 99
    • 0030999750 scopus 로고    scopus 로고
    • Apoptosis and dilemna of cancer chemotherapy
    • (1997) Blood , vol.89 , pp. 1845-1853
    • Hannun, Y.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.