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Volumn 53, Issue 2, 2001, Pages 176-183

T-cell receptor downregulation by ceramide-induced caspase activation and cleavage of the ζ chain

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CD3 ANTIGEN; CERAMIDE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ZETA CHAIN; UNCLASSIFIED DRUG;

EID: 0035128799     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2001.00852.x     Document Type: Article
Times cited : (13)

References (33)
  • 6
    • 0027379699 scopus 로고
    • Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p561ck tyrosine kinase: Basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules
    • (1993) J Exp Med , vol.178 , pp. 1701-1712
    • Wiest, D.L.1    Yuan, L.2    Jefferson, J.3
  • 8
    • 0028179026 scopus 로고
    • CD3 gamma contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor
    • (1994) EMBO J , vol.13 , pp. 2156-2166
    • Dietrich, J.1    Hou, X.2    Wegener, A.M.3
  • 11
    • 15144359445 scopus 로고    scopus 로고
    • Ceramide formation leads to caspase-3 activation during hypoxic PC12 cell death. Inhibitory effects of Bcl-2 on ceramide formation and caspase-3 activation
    • (1998) J Biol Chem , vol.273 , pp. 6921-6927
    • Yoshimura, S.1    Banno, Y.2    Nakashima, S.3
  • 15
    • 0030985969 scopus 로고    scopus 로고
    • T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: The molecular basis of negative selection
    • (1997) EMBO J , vol.16 , pp. 2282-2293
    • Clayton, L.K.1    Ghendler, Y.2    Mizoguchi, E.3
  • 21
    • 0030849093 scopus 로고    scopus 로고
    • A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
    • (1997) J Biol Chem , vol.272 , pp. 17907-17911
    • Thornberry, N.A.1    Rano, T.A.2    Peterson, E.P.3
  • 22
    • 0033378016 scopus 로고    scopus 로고
    • Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells
    • (1999) J Exp Med , vol.190 , pp. 1879-1890
    • Alam, A.1    Cohen, L.Y.2    Aouad, S.3
  • 26
    • 0027327212 scopus 로고
    • Tumor necrosis factor-alpha (TNF-alpha) signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-alpha from activation of nuclear factor-kappa B
    • (1993) J Biol Chem , vol.268 , pp. 17762-17766
    • Dbaibo, G.S.1    Obeid, L.M.2    Hannun, Y.A.3
  • 27
    • 0027994349 scopus 로고
    • The sphingomyelin cycle and the second messenger function of ceramide
    • (1994) J Biol Chem , vol.269 , pp. 3125-3128
    • Hannun, Y.A.1
  • 29
    • 0028297068 scopus 로고
    • The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling
    • (1994) Cell , vol.77 , pp. 325-328
    • Kolesnick, R.1    Golde, D.W.2
  • 30
    • 0027461121 scopus 로고
    • Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta
    • (1993) Science , vol.259 , pp. 519-522
    • Mathias, S.1    Younes, A.2    Kan, C.C.3
  • 31
    • 0033577806 scopus 로고    scopus 로고
    • A role for neutral sphingomyelinase-mediated ceramide production in T cell receptor-induced apoptosis and mitogen-activated protein kinase-mediated signal transduction
    • (1999) J Exp Med , vol.189 , pp. 1581-1589
    • Tonnetti, L.1    Veri, M.C.2    Bonvini, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.