Qualitative and quantitative contributions of the T cell receptor ζ chain to mature T cell apoptosis

Journal of Experimental Medicine

Volumn 183, Issue 5, 1996, Pages 2109-2117

  Combadière, Behazine ^a   Freedman, Matthew ^a   Chen, Lina ^a   Shores, Elizabeth W ^b   Love, Paul ^c   Lenardo, Michael J ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR;

APOPTOSIS; ARTICLE; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; IMMUNOLOGICAL TOLERANCE; IMMUNOREACTIVITY; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUALITATIVE DIAGNOSIS; QUANTITATIVE DIAGNOSIS; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; CELLS, CULTURED; CLONE CELLS; DNA; DNA PRIMERS; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TETRADECANOYLPHORBOL ACETATE; VARIATION (GENETICS);

EID: 0029891157     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.5.2109     Document Type: Article

References (45)

1. Wyllie, A.H. 1995. The genetic regulation of apoptosis. Curr. Opin. Genet. Dev. 5:97-104.
2. Hengartner, M.O., and H.R. Horvitz. 1994. Programmed cell death in Caenorhabditis elegans. Curr. Opin. Genet. Dev. 4:581-586.
3. Cohen, J.J., R.C. Duke, V.A. Fadok, and K.S. Sellins. 1992. Apoptosis and cell death in immunity. Annu. Rev. Immunol. 10:267-293.
4. Green, D.R., R.P. Bissonnette, J.M. Glynn, and Y. Shi. 1992. Activation-induced apoptosis in lymphoid systems. Sem. Immunol. 4:379-388.
5. Critchfield, M.J., S.A. Boehme, and M.J. Lenardo. 1995. The regulation of antigen-induced apoptosis in mature T lymphocytes. In Apoptosis and the Immune Response. C. Gregory, editor. Wiley-Liss, Inc., New York. 55-114.
6. Smith, C.A., G.T. Williams, R. Kingston, E.J. Jenkinson, and J.J.T. Owen. 1989. Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature (Lond.). 337:181-184.
7. lo thymocytes in vivo. Science (Wash. DC). 250:1720-1723.
8. Allen, P.M. 1994. Peptides in positive and negative selection: a delicate balance. Cell 76:593-596.
9. Lenardo, M.J. 1991. Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. Nature (Lond.). 353:858-861.
10. Russell, J.H., C.L. White, D.Y. Loh, and P. Melleedy-Rey. 1991. Receptor-stimulated death pathway is opened by antigen in mature T cells. Prof. Natl. Acad. Sci. USA. 88:2151-2157.
11. Critchfield, J.M., J.C. Zuniga-Pflucker, and M.J. Lenardo. 1995. Parameters controlling apoptosis in high dose suppression of mature T lymphocytes. Cell. Immunol. 160:71-78.
12. Singer, G.G., and A.K. Abbas. 1994. The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity. 1:365-373.
13. Clevers, H., B. Alarcon, T. Wileman, and C. Terhorst. 1988. The T cell receptor/CD3 complex: a dynamic protein ensemble. Annu. Rev. Immunol. 6:629-662.
14. Ashwell, J.D., and R.D. Klausner. 1990. Genetic and mutational analysis of the T-cell antigen receptor. Annu. Rev. Immunol. 8:139-167.
15. Reth, M. 1989. Antigen receptor tail clue. Nature (Lond.). 338:383-384.
16. Samelson, L.E., and R.D. Klausner. 1992. Tyrosine kinases and tyrosine-based activation motifs. J. Biol. Chem. 267: 24913-24916.
17. Cambier, J.C. 1995. New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL). Immunology Today. 16: 110.
18. fyn. Cell. 65:281-291.
19. lck with CD4 in antigen-specific signal transduction in T cells. Cell. 64:511-520.
20. Samelson, L.E., A.F. Philips, E.T. Luong, and R.D. Klausner. 1990. Association of the fyn protein-tyrosine kinase with the T cell antigen receptor. Proc. Natl. Acad. Sci. USA. 87:4358-4362.
21. Straus, D., and A. Weiss. 1992. Genetic evidence for involvement of lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell. 70:585-593.
22. Songyang, Z., S.E. Shoelson, M. Chaudhuri, G. Gish, T. Pawson, W.G. Haser, F. King, T. Roberts, S. Ratnofsky, R.J. Lechleider et al. 1993. SH2 domains recognize specific phosphopeptide sequences. Cell. 72:767-778.
23. Songyang, Z., S.E. Shoelson, J. McGlade, P. Olivier, T. Pawson, X.R. Bustelo, M. Barbacid, H. Sabe, H. Hanafusa, T. Yi et al. 1994. Specific motifs recognized by SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. Mol. Cell. Biol. 14:2777-2785.
24. Isakov, N., R.L. Wange, W.H. Burgess, J.D. Watts, R. Aebersold, and L.E. Samelson. 1995. ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity. J. Exp. Med. 181:375-380.
25. Frank, S.J., C. Cenciarelli, B.B. Niklinski, F. Letourneur, J.D. Ashwell, and A.M. Weissman. 1992. Mutagenesis of T cell antigen receptor ζ chain tyrosine residues. J. Biol. Chem. 267:13656-13660.
26. Irving, B.A., A.C. Chan, and A. Weiss. 1993. Functional characterization of a signal transducing motif present in the T cell antigen receptor ζ chain. J. Exp. Med. 177:1093-1103.
27. Donnadieu, E., A. Trautmann, M. Malissen, J. Trucy, B. Malissen, and E. Vivier. 1994. Reconstitution of CD3ζ coupling to calcium mobilization via genetic complementation. J. Biol. Chem. 269:32828-32834.
28. Irving, B.A., and A. Weiss. 1991. The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways. Cell. 64:891-901.
29. Letourneur, F., and R.D. Klausner. 1992. Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3e. Science (Wash. DC). 255:79-82.
30. Romeo, C., M. Amiot, and B. Seed. 1992. Sequence requirements for induction of cytolysis by the T cell antigen/Fc receptor zeta chain. Cell. 68:889-897.
31. Weiss, A., and D.R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell. 76:263-274.
32. Shinkai, Y., A. Ma, H. Cheng, and F.W. Alt. 1995. CD3∈ and CD3ζ cytoplasmic domains can independently generate signals for T cell development and function. Immunity. 2: 401-411.
33. Wegener, A.-M.K., F. Letourneur, A. Hoeveler, T. Brocker, F. Luton, and B. Malissen. 1992. The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell. 68:83-95.
34. Hermans, M.H.A., and B. Malissen. 1993. The cytoplasmic tail of the T cell receptor ζ chain is dispensable for antigen-mediated T cell activation. Eur. J. Immunol. 23:2257-2262.
35. Vignaux, F., E. Vivier, B. Malissen, V. Depraetere, S. Nagata, and P. Golstein. 1995. TCR/CD3 coupling to Fas-based cytotoxicity. J. Exp. Med. 181:781-786.
36. Higuchi, R., B. Krummel, and R.K. Saiki. 1988. A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res. 16:7351-7367.
37. Takebe, Y., M. Seiki, J. Fujisawa, P. Hoy, K. Yokota, K. Arai, M. Yoshida, and N. Arai. 1988. SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long. Mol. Cell. Biol. 8:466-472.
38. Love, P.E., E.W. Shores, M.D. Johnson, M.L. Temblay, E.J. Lee, A. Grinberg, S.P. Huang, A. Singer, and H. Westphal. 1993. T cell development in mice that lack the ζ chain of the T cell antigen receptor complex. Science (Wash. DC). 261: 918-921.
39. Shores, E.W., K. Huang, T. Tran, R. Lee, A. Grinberg, and P.E. Love. 1994. Role of TCR-ζ chain in T cell development and selection. Science (Wash. DC). 266:1047-1050.
40. Boehme, S.A., and M.J. Lenardo. 1993. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur. J. Immunol. 23:1552-1560.
41. Leo, O., M. Foo, D.H. Sachs, L.E. Samelson, and J.A. Bluestone. 1987. Identification of a monoclonal antibody specific for murine T3 polypeptide. Proc. Natl. Acad. Sci. USA. 84: 1374-1379.
42. Oh-Ishi, R.T., C.K. Goldman, and T.A. Waldmann. 1989. The interaction of interleukin-2 with its receptor in the generation of suppressor T cells in antigen specific and antigen-nonspecific system in vitro. Clin. Immunol. Immunopathol. 52: 447-459.
43. Boehme, S.A., and M.J. Lenardo. 1993. Ligand-induced apoptosis of mature T lymphocytes (propriocidal regulation) occurs at distinct stages of the cell cycle. Leukemia (Baltimore). 7: S45-S49.
44. Sussman, J.J., J.S. Bonifacino, J. Lippincott-Schwartz, A.M. Weissman, T. Saito, R.D. Klausner, and J.D. Ashwell. 1988. Failure to synthesize the T cell CD3-zeta chain: structure and function of a partial T cell receptor complex. Cell. 52:85-95.
45. Lenardo, M.J., S. Boehme, L. Chen, B. Combadiere, G. Fisher, M. Freedman, H. McFarland, C. Pelfrey, and L. Zheng. 1995. Autocrine feedback death and the regulation of mature T lymphocyte antigen responses. Int. Rev. Immunol. 13:115-134.