Salmonella: A model for bacterial pathogenesis

Annual Review of Medicine

Volumn 52, Issue , 2001, Pages 259-274

  Ohl, M E ^a   Miller, S I ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Antimicrobial peptide; Innate immunity; Macrophage; Type III secretion

Indexed keywords

BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIAL VIRULENCE; EXPERIMENTAL MODEL; GASTROENTERITIS; HUMAN; IMMUNE SYSTEM; INFLAMMATION; INTESTINE EPITHELIUM; INTESTINE SECRETION; MONONUCLEAR PHAGOCYTE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SALMONELLA;

DNA, BACTERIAL; GENOME, BACTERIAL; HUMANS; IMMUNITY, MUCOSAL; INFLAMMATION; INTESTINAL MUCOSA; MACROPHAGES; MOLECULAR BIOLOGY; SALMONELLA; SALMONELLA INFECTIONS; SEROTYPING;

EID: 0035123755     PISSN: 00664219     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.med.52.1.259     Document Type: Review

References (54)

1. Innate immune recognition: Mechanisms and pathways
2. Salmonella species, including Salmonella typhi
3. Gastric acid barrier to ingested microorganisms in man: Studies in vivo and in vitro
4. Role of acid tolerance response genes in Salmonella typhimurium virulence
5. Contribution of fimbrial operons to attachment to and invasion of epithelial cell lines by Salmonella typhimurium
6. Morphological and cytoskeletal changes in epithelial cells occur immediately upon interaction with Salmonella typhimurium grown under low-oxygen conditions
7. Molecular and cellular bases of Salmonella entry into host cells
8. Requirement of CDC42 for Salmonella-induced cytoskeletal and nuclear responses
9. Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches
10. Overview of the mucosal immune system
11. Characterization of intestinal invasion by Salmonella typhimurium and Salmonella dublin and effect of a mutation in the invH gene
12. Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes
13. A secreted effector protein of Salmonella dublin is translocated into eukaryotic cells and mediates inflammation and fluid secretion in infected ileal mucosa
14. Salmonella typhimurium attachment to human intestinal epithelial monolayers: Transcellular signalling to subepithelial neutrophils
15. Salmonellae stimulate macrophage macropinocytosis and persist within spacious phagosomes
16. Pathogenicity islands: Bacterial evolution in quantum leaps
17. Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival
18. Genes encoding putative effector proteins of the type In secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages
19. Type III protein secretion systems in bacterial pathogens of animals and plants
20. Supramolecular structure of the Salmonella typhimurium type III protein secretion system
21. A conserved amino acid sequence directing intracellular type III secretion by Salmonella typhimurium
22. Isolation of a temperate bacteriophage encoding the type III effector protein SopE from an epidemic Salmonella typhimurium strain
23. D-myo-inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways
24. Mutation of invH, but not stn, reduces Salmonella-induced enteritis in cattle
25. Involvement of mitogen-activated protein kinase pathways in the nuclear responses and cytokine production induced by Salmonella typhimurium in cultured intestinal epithelial cells
26. Signal transduction and invasion of epithelial cells by S. typhimurium
27. Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cells
28. S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells
29. A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion
30. Rho GTPases and the actin cytoskeleton
31. Role of the S. typhimurium actin-binding protein SipA in bacterial internalization
32. Direct nucleation and bundling of actin by the SipC protein of invasive Salmonella
33. The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells
34. SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase
35. A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurium
36. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
37. A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence
38. Signalling pathways in two-component phosphorelay systems
39. PhoP/PhoQ transcriptional repression of Salmonella typhimurium invasion genes: Evidence for a role in protein secretion
40. Constitutive expression of the phoP regulon attenuates Salmonella virulence and survival within macrophages
41. Lipid A acylation and bacterial resistance against vertebrate antimicrobial peptides
42. Antimicrobial peptides of phagocytes and epithelia
43. Regulation of lipid A modifications by Salmonella typhimurium virulence genes phoP-phoQ
44. Identification of a pathogenicity island required for Salmonella survival in host cells
45. Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium
46. Fluorescence-based isolation of bacterial genes expressed within host cells
47. A Salmonella virulence protein that inhibits cellular trafficking
48. Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase
49. Homocysteine antagonism of nitric oxide-related cytostasis in Salmonella typhimurium
50. Virulent Salmonella typhimurium has two periplasmic Cu, Zn-superoxide dismutases
51. The alternative sigma factor katF (rpoS) regulates Salmonella virulence
52. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines
53. Effect of different purine auxotrophic mutations on mouse-virulence of a Vi-positive strain of Salmonella dublin and of two strains of Salmonella typhimurium
54. Microbial pathogenesis: Genomics and beyond