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note
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We thank D. Botstein, D. Brutlag, B. Cormack, D. Frank, T. McDaniel, J. F. Miller, K. Ottemann, B. Raupach, and R. Valdivia for helpful discussions and critical comments on the manuscript. We also thank P. Sansonetti for providing Fig. 1B. Supported by an American Cancer Society postdoctoral fellowship (grant PF-4120) to E.J.S. and USPHS grant AI 26195 to S.F.
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