Herpes simplex virus-induced keratitis: Evaluation of the role of molecular mimicry in lesion pathogenesis

Journal of Virology

Volumn 75, Issue 7, 2001, Pages 3077-3088

  Deshpande, S P ^a   Lee, S ^a   Zheng, M ^a   Song, B ^a   Knipe, D ^a   Kapp, J A ^a   Rouse, B T ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G2A; PEPTIDE DERIVATIVE; VIRUS ANTIGEN; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; CROSS REACTION; DISEASE SEVERITY; HERPES SIMPLEX VIRUS; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; KERATITIS; MOLECULAR MIMICRY; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; T LYMPHOCYTE; VACCINIA VIRUS; VIRUS INFECTION;

ANIMALS; AUTOIMMUNE DISEASES; CAPSID; CAPSID PROTEINS; CROSS REACTIONS; GENETIC PREDISPOSITION TO DISEASE; HERPESVIRUS 1, HUMAN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAINS; KERATITIS, HERPETIC; MICE; MICE, SCID;

EID: 0035103878     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.7.3077-3088.2001     Document Type: Article

References (41)

1. Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes
2. Resistance to herpes stromal keratitis conferred by an IgG2a derived peptide
3. Viral replication is required for induction of ocular immunopathology by herpes simplex virus
4. Viral induced neurodegenerative disease
5. Modulation of viral immunoinflammatory responses with cytokine DNA administered by different routes
6. Virus-induced immunoinflammatory lesions in the absence of viral antigen recognition
7. + T cells can represent an exclusive means of immunopathology in a virus infection
8. + T cells accounts for herpetic ocular lesions
9. Pancreatic expression of interferon γ protects mice from lethal coxsackie virus B3 infection and subsequent myocarditis
10. Viruses, host responses and autoimmunity
11. Diabetes induced by coxsackie virus: Initiation by bystander damage and not molecular mimicry
12. Coxssackievirus B-3 myocarditis in BALB/c mice: Evidence for autoimmunity to myocyte antigens
13. A B cell deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene
14. Genetic immunization against herpes simplex virus. Protection is mediated by CD4 T lymphocytes
15. Analysis of the HSV UL6 encoding region in patients with recurrent HSV keratitis
16. Herpetic stromal keratitis in the reconstituted SCID mouse model
17. Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading
18. Role of macrophages and dendritic cells in primary cytotoxic T lymphocyte responses
19. Molecular mimicry and immune-mediated diseases
20. Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model
21. Immunogenetic influence of IgH-1 phenotype on experimental herpes simplex virus type-1 corneal infection
22. D011.10 and OT-11 T cells recognize a C-terminal ovalbumin 323-339 epitope
23. Viral damage or 'molecular mimicry': Placing the blame in myocarditis
24. Immunopathogenesis of dengue hemorrhagic fever
25. Virus-induced immunopathology
26. A balance of powers
27. Dominance and crypticity of T cell antigenic determinants
28. Passive immunization protects the mouse eye from damage after herpes simplex virus infection by limiting spread of virus in the nervous system
29. Herpes simplex virus infection blocks events in G1 phase of the cell cycle
30. Proteins specified by herpes simplex virus. V. Purification and structural proteins of the herpes virion
31. Immunity causing blindness: Five different paths to herpes stromal keratitis
32. Molecular mechanisms of Coxsackie persistence in chronic inflammatory myopathy: Viral RNA persists through formation of a double-stranded complex without associated genomic mutations or evolution
33. The herpes simplex virus 1 UL17 gene is required for localization of capsids and major and minor capsid proteins to intranuclear sites where viral DNA is cleaved and packaged
34. Autoimmune reactions against myelin basic proteins induced by corona virus and measles virus
35. + T cell function between euthymic host and reconstituted SCID recipients
36. Immunopathogenesis of herpetic ocular disease
37. Herpes simplex virus specific T-cells infiltrate the cornea of patients with herpetic stromal keratitis (HSK): No evidence for intra-corneal autore-active T-cells in human HSK
38. Virus-induced autoimmune disease
39. Viruses as triggers of autoimmunity: Facts and fantasies
40. Molecular mimicry in T cell mediates autoimmunity: Viral peptides activate human T cell clones specific for MBP
41. Molecular mimicry by herpes simplex virus type-1: Autoimmune disease after viral infection