Maxi-K potassium channels: Form, function, and modulation of a class of endogenous regulators of intracellular calcium

Neuroscientist

Volumn 7, Issue 2, 2001, Pages 166-177

  Gribkoff, Valentin K ^a   Starrett, John E ^a   Dworetzky, Steven I ^a  

^a BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

Author keywords

BK channel; Ischemia; Maxi K channel; Neuron; Potassium channel; Slo channel

Indexed keywords

1 (2 HYDROXY 5 TRIFLUOROMETHYLPHENYL) 5 TRIFLUOROMETHYL 2(3H) BENZIMIDAZOLONE; POTASSIUM CHANNEL;

BRAIN ISCHEMIA; CALCIUM CELL LEVEL; COGNITIVE DEFECT; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; NEUROBIOLOGY; NEUROMODULATION; NEUROTRANSMITTER RELEASE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; CALCIUM; INTRACELLULAR MEMBRANES; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MOLECULAR BIOLOGY; MOLECULAR SEQUENCE DATA; NEURONS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED;

EID: 0035081572     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/107385840100700211     Document Type: Review

References (86)

1. Calcium-activated potassium channels expressed from cloned complementary DNAs
2. A component of calcium-activated potassium channels encoded by the Drosophila slo Locus
3. Single-channel activity in cultured cortical neurons of the rat in the presence of a toxic dose of glutamate
4. Cloning and functional characterization of novel large-conductance calcium-activated potassium channel β subunits, hKCNMB3 and hKCNMB4
5. mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels
6. 2+channels and snare proteins in neurotransmitter release
7. Differential expression of the a and b subunits of the large conductance calcium-activated potassium channel: Implication for channel diversity
8. Calcium: Still center-stage in hypoxic-ischemic neuronal death
9. pH modulation of Ca2+ responses and a Ca2+-dependent K+ channel in cultured rat hippocampal neurones
10. Phenotypic alteration of a human BK (hSlo) channel by hSloβ subunit coexpression: Changes in blocker sensitivity, activation/relaxation and inactivation kinetics, and protein kinase A modulation
11. Cloning and expression of a human large-conductance calcium-activated potassium channel
12. Cognition enhancement strategies by ion channel modulation of neurotransmission
13. Mechanisms of hair cell tuning
14. Involvement of hippocampal synaptic plasticity in age-related memory decline
15. Dendritic calcium spike initiation and repolarization are controlled by distinct potassium channel subtypes in CA1 pyramidal neurons
16. Endogenous adenosine contributes to hypoxic synaptic depression in hippocampus from young and aged rats
17. The pharmacology and molecular biology of large-conductance calcium-activated (BK) potassium channels
18. Mutations in the K+ channel signature sequence
19. Ca2+-dependent inactivation of large conductance Ca2+-activated K+ (BK) channels in rat hippocampal neurones produced by pore block from an associated particle
20. The hypoxic brain. Insights from ischemia research
21. 2+activated K+ channels at fluorescently labeled presynaptic active zones of hair cells
22. Voltage-gated and inwardly rectifying potassium channels
23. Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits
24. ATP-sensitive and Ca-activated K channels in vertebrate axons: Novel links between metabolism and excitability
25. +channel spliced variants in the tonotopic organization of the turtle cochlea
26. Induction of seizures by the potent K+ channel-blocking scorpion venom peptide toxins tityustoxin-K(alpha) and pandinustoxin-K(alpha)
27. Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel
28. Voltage-gated potassium channels activated during action potentials in layer V neocortical pyramidal neurons
29. +channel from smooth muscle
30. +channels in rat brain: Targeting to axons and nerve terminals
31. Functional differences among alternatively spliced variants of Slowpoke, a Drosophila calcium-activated potassium channel
32. Properties of two calcium-activated hyperpolarizations in rat hippocampal neurones
33. Varieties of calcium-activated potassium channels
34. The effects of neuroleptc and tricyclic compounds on BK(Ca) channel activity in rat isolated cortical neurones
35. NS 1619 activates BK(Ca) channel activity in rat cortical neurones
36. A pH-sensitive yeast outward rectifier K+ channel with two pore domains and novel gating properties
37. O(2) deprivation inhibits Ca(2+)-activated K(+) channels via cytosolic factors in mice neocortical neurons
38. Neuroregulation by vasoactive intestinal peptide (VIP) of mucus secretion in ferret trachea: Activation of BK(Ca) channels and inhibition of neurotransmitter release
39. Neuroprotection in acute ischaemic stroke. Current status and future potential
40. Selective activation of Ca2+-activated K+ channels by co-localized Ca2+ channels in hippocampal neurons
41. Opening of large-conductance calcium-activated potassium channels by the substituted benzimidazolone NS004
42. Calcium-activated potassium channels: Regulation by calcium
43. Functional role of the β-subunit of high conductance calcium-activated potassium channels
44. +channel resistant to charybdotoxin and iberiotoxin
45. Ion channels in presynaptic nerve terminals and control of transmitter release
46. Cerebrovasc protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission
47. 2+channels
48. NS 004 is neuroprotective in rodent models of global and focal cerebral ischemia
49. Cloning and characterization of human and mouse homologs of the Drosphila calcium-activated potassium channel gene, slowpoke
50. Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila
51. Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence
52. Calcium-activated potassium channels and their role in secretion
53. BK channel activation by brief depolarizations requires Ca2+ influx through L- and Q-type Ca2+ channels in rat chromaffin cells
54. β subunits modulate alternatively spliced, large conductance, calcium-activated potassium channels of avian hair cells
55. A molecular mechanism for electrical tuning of cochlear hair cells
56. A family of calcium-dependent potassium channels from rat brain
57. Inactivation properties of voltage-gated K+ channels altered by presence of b-subunits
58. Identification of a putative regulatory subunit of a calcium-activated potassium channel in the dup(3q) syndrome region and a related sequence on 22q11.2
59. Presynaptic calcium signals and transmitter release are modulated by calcium-activated potassium channels
60. Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release
61. NMDA receptors amplify calcium influx into dendritic spines during associative pre- and postsynaptic activation
62. +channel from mammalian spermatocytes
63. Transplantable sites confer calcium sensitivity to BK channels
64. Activation of BK(Ca) channels in acutely dissociated neurones from the rat ventromedial hypothalamus by NS 1619
65. The role of BK-type Ca2+-dependent K+ channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells
66. Tetraethylammonium block of Slowpoke calcium-activated potassium channels expressed in Xenopus oocytes: Evidence for tetrameric channel formation
67. MaxiK channels: Molecular structure, function, and tissue distribution
68. Biology of ischemic cerebral cell death
69. Modulators of large-conductance calcium-activated potassium (BK) channels as potential therapeutic targets
70. Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells
71. Single-channel properties of BK-type calcium-activated potassium channels at a cholinergic presynaptic nerve terminal
72. Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila
73. +channel isoforms from human brain
74. Cloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brain
75. Acute activation of maxi-K channels (hSlo) by estradiol binding to the β subunit
76. Potassium channel activators protect the N-methyl D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets
77. +channels: An additional transmembrane region at the N terminus
78. Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: A transmembrane β-subunit homolog
79. Conserved classes of potassium channel genes identified from the Caenorhabditis elegans genome
80. cachannels determined by a separable domain
81. Molecular basis for the inactivation of Ca2+- and voltage dependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells
82. Control of alternative splicing of potassium channels by stress hormones
83. +currents in canine coronary artery smooth muscle cells by NS-004, or 1-(2′-hydroxy-5′ chlorophenyl)-5-trifluoromethyl-2(3H) benzimidazolone