The role of Ca2+-activated K+ channel spliced variants in the tonotopic organization of the turtle cochlea

Journal of Physiology

Volumn 518, Issue 3, 1999, Pages 653-665

  Jones, E M C ^a   Gray Keller, M ^a   Fettiplace, R ^a,b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b 185 Medical Sciences Building ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; MEMBRANE PROTEIN; POTASSIUM CHANNEL; PROTEIN SUBUNIT; CALCIUM ACTIVATED POTASSIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL BETA SUBUNIT; MESSENGER RNA;

ALPHA CHAIN; ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; COCHLEA; CONTROLLED STUDY; GENE DELETION; GENE INSERTION; HAIR CELL; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TONOTOPY; TURTLE; XENOPUS; BETA CHAIN; CALCIUM CELL LEVEL; CALCIUM CONDUCTANCE; CALCIUM MOBILIZATION; CELLULAR DISTRIBUTION; COCHLEA POTENTIAL; PROTEIN FUNCTION; XENOPUS LAEVIS; ANIMAL; AUDITORY STIMULATION; BIOSYNTHESIS; CATTLE; CHICK EMBRYO; ELECTROPHYSIOLOGY; GENETICS; ISOMERISM; KINETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; QUAIL; RNA SPLICING;

ACOUSTIC STIMULATION; AMINO ACID SEQUENCE; ANIMALS; CATTLE; CHICK EMBRYO; COCHLEA; ELECTROPHYSIOLOGY; HAIR CELLS, INNER; ISOMERISM; KINETICS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL BETA SUBUNITS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MOLECULAR SEQUENCE DATA; OOCYTES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; QUAIL; RNA SPLICING; RNA, MESSENGER; SEQUENCE DELETION; TURTLES; XENOPUS;

EID: 0033179454     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1999.0653p.x     Document Type: Article

References (37)

1. ART, J. J. & FETTIPLACE, R. (1987). Variation of membrane properties in hair cells isolated from the turtle cochlea. Journal of Physiology 385, 207-242.
2. ART, J. J., WU, Y.-C. & FETTIPLACE, R. (1995). The calcium-activated potassium channels of turtle hair cells. Journal of General Physiology 105, 49-72.
3. BERS, D. M., PATTON, C. W. & NUCCITELLI, R. (1994). A practical guide to the preparation of calcium buffers. Methods in Cell Biology 40, 3-29.
4. 2+ channels and membrane fluidity in vascular smooth muscle. Pflügers Archiv 415, 262-268.
5. BUTLER, A., TSUNODA, S., MCCOBB, D. P., WEI, A. & SALKOFF, L. (1993). mSlo, a complex mouse gene encoding 'maxi' calcium-activated potassium channels. Science 261, 221-224.
6. COLQUHOUN, D. & SACKMANN, B. (1985). Fast events in single-channel currents activated by acetylcholine and its analogues at the frog neuromuscular end-plate. Journal of Physiology 369, 501-557.
7. + channel. Journal of General Physiology 110, 257-281.
8. CRAWFORD, A. C. & FETTIPLACE, R. (1980). The frequency selectivity of auditory nerve fibres and hair cells in the cochlea of the turtle. Journal of Physiology 306, 79-125.
9. + channels. Journal of Neuroscience 17, 4942-4955.
10. DWORETZKY, S. I., BOISSARD, C. G., LUM-REGAN, J. T., MCKAY, M. C., POST-MUNSON, D. J., TROJNACKI, J. T., CHANG, C.-P. & GRIBKOFF, V. K. (1996). Phenotypic alteration of a human BK (hSlo) channel by hSloβ subunit coexpression: changes in blocker sensitivity, activation/relaxation and inactivation kinetics, and protein kinase A modulation. Journal of Neuroscience 16, 4543-4550.
11. JIANG, G.-J., ZIDANIC, M., MICHAELS, R. L., MICHAEL, T. H., GRIGUER, C. & FUCHS, P. A. (1997). cSlo encodes calcium-activated potassium channels in the chick's cochlea. Proceedings of the Royal Society B 264, 731-737.
12. + channel splice variants and their distribution in the turtle cochlea. Proceedings of the Royal Society B 265, 685-692.
13. KACZOROWSKI, G. J., KNAUS, H.-G., LEONARD, R. J., MCMANUS, O. B. & GARCIA, M. L. (1996). High-conductance calcium-activated potassium channels: structure pharmacology and function. Journal of Bioenergetics and Biomemembranes 28, 255-267.
14. LAGRUTTA, A., SHEN, K.-Z., NORTH, R. A. & ADELMAN, J. P. (1994). Functional differences among alternatively spliced variants of slowpoke, a Drosophila calcium-activated potassium channel. Journal of Biological Chemistry 269, 20347-20351.
15. MCMANUS, O. B., HELMS, L. M., PALLANCK, L., GANETZKY, B., SWANSON, R. & LEONARD, R. J. (1995). Functional role of the β-subunit of high conductance calcium-activated potassium channels. Neuron 14, 645-650.
16. + channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N-terminus, and an intracellular (S9-S10) C-terminus. Proceedings of the National Academy of Sciences of the USA 94, 14066-14071.
17. + channel splice variants among hair cells along the tonotopic axis of the chick cochlea. Neuron 19, 1077-1085.
18. OBERST, C., WEISKIRCHEN, R., HARTL, M. & BISTER, K. (1997). Suppression in transformed avian fibroblasts of a gene (CO6) encoding a membrane protein related to mammalian potassium channel regulatory subunits. Oncogene 14, 1109-1116.
19. PASCARELLA, S. & ARGOS, P. (1992). Analysis of insertions/deletions in protein structures. Journal of Molecular Biology 224, 461-471.
20. RAMANATHAN, K., MICHAEL, T. H., JIANG, G.-J., HIEL, H. & FUCHS, P. A. (1999). A molecular mechanism for electrical tuning of cochlear hair cells. Science 283, 215-217.
21. ROBERTSON, G. A., WARMKE, J. M. & GANETZKY, B. (1996). Potassium currents expressed from Drosophila and mouse eag cDNAs in Xenopus oocytes. Neuropharmacology 35, 841-850.
22. ROBITAILLE, R. & CHARLTON, M. P. (1992). Presynaptic calcium signals and transmitter release are modulated by calcium-activated potassium channels. Journal of Neuroscience 12, 297-305.
23. + channel isoforms along the tonotopic gradient of the chicken's cochlea. Neuron 19, 1061-1075.
24. SCHOPPERLE, W. M., HOLMQVIST, M. H., ZHOU, Y., WANG, J., WANG, Z., GRIFFITH, L. C., KESELMAN, I., KUSINITZ, F., DAGAN, D. & LEVITAN, I. B. (1998). Slob, a novel protein that interacts with the slowpoke calcium-dependent potassium channel. Neuron 20, 565-573.
25. SCHREIBER, M. & SALKOFF, L. (1997). A novel calcium sensing domain in the BK channel. Biophysical Journal 73, 1355-1363.
26. SHEN, K.-Z., LAGRUTTA, A., DAVIES, N. W., STANDEN, N. B., ADELMAN, J. P. &, NORTH, R. A. (1994). Tetraethylammonium block of Slowpoke calcium-activated potassium channels expressed in Xenopus ooccytes: evidence for tetrameric channel formation. Pflügers Archiv 426, 440-445.
27. + channel, expressed in oocytes. Biophysical Journal 70, 2640-2651.
28. STÜHMER, W. & PAREKH, A. B. (1995). Electrophysiological recordings from Xenopus oocytes. In Single-Channel Recording, 2nd edn, ed. SAKMANN, B. & NEHER, E., pp. 341-356. Plenum Press, New York and London.
29. SULLIVAN, D. A., HOLMQVIST, M. H. & LEVITAN, I. B. (1997). Characterization of gating and peptide block of mSlo, a cloned calcium-activated potassium channel. Journal of Neurophysiology 78, 2937-2950.
30. + channel isoforms from human brain. Neuron 13, 1315-1330.
31. TSIEN, R. W. & RINK, T. J. (1980). Neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium. Biochimica et Biophysica Acta 599, 623-638.
32. Ca channels. An additional transmembrane region at the N-terminus. Proceedings of the National Academy of Sciences of the USA 93, 14922-14927.
33. + channels: a transmembrane β-subunit homolog. Proceedings of the National Academy of Sciences of the USA 96, 4137-4142.
34. Ca channels determined by a separable domain. Neuron 13, 671-681.
35. WU, Y.-C., ART, J. J., GOODMAN, M. B. & FETTIPLACE, R. (1995). A kinetic description of the calcium-activated potassium channel and its application to electrical tuning of hair cells. Progress in Biophysics and Molecular Biology 63, 131-158.
36. WU, Y.-C. & FETTIPLACE, R. (1996). A developmental model for generating frequency maps in the reptilian and avian cochleas. Biophysical Journal 70, 2557-2570.
37. XIE, J. & MCCOBB, D. P. (1998). Control of alternative splicing of potassium channels by stress hormones. Science 280, 443-446.