β subunits modulate alternatively spliced, large conductance, calcium- activated potassium channels of avian hair cells

Journal of Neuroscience

Volumn 20, Issue 5, 2000, Pages 1675-1684

  Ramanathan, Krishnan ^a   Michael, Timothy H ^a   Fuchs, Paul A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alternative splicing; Avian; Calcium activated potassium channel; Chick; Cochlea; Electrical tuning; Hair cell; subunits

Indexed keywords

CALCIUM; COMPLEMENTARY DNA; GENE PRODUCT; POTASSIUM CHANNEL;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; BETA CHAIN; CALCIUM BINDING; CHANNEL GATING; COCHLEA; DNA DETERMINATION; ELECTRIC POTENTIAL; FOWL; GENETIC TRANSFECTION; HAIR CELL; HUMAN; HUMAN CELL; KINETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 0034161491     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-05-01675.2000     Document Type: Article

References (47)

1. Adelman JP, Shen KZ, Kavanaugh MP, Warren RA, Wu YN, Lagrutta A, Bond CT, North RA (1992) Calcium-activated potassium channels expressed from cloned complementary DNAs. Neuron 9:209-216.
2. Art JJ, Fettiplace R (1987) Variation of membrane properties in hair cells isolated from the turtle cochlea. J Physiol (Lond) 385:207-242.
3. Art JJ, Wu YC, Fettiplace R (1995) The calcium-activated potassium channels of turtle hair cells. J Gen Physiol 105:49-72.
4. Atkinson NS, Robertson GA, Ganetzky B (1991) A component of calcium-activated potassium channels encoded by the Drosophila slo locus. Science 253:551-555.
5. Bers DM, Patton CW, Nuccitelli R (1994) A practical guide to the preparation of Ca2+ buffers. Methods Cell Biol 40:3-29.
6. Butler A, Tsunoda S, McCobb DP, Wei A, Salkoff L (1993) mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Science 261:221-224.
7. Chen L, Salvi R, Shero M (1994) Cochlear frequency-place map in adult chickens: intracellular biocytin labeling. Hear Res 81:130-136.
8. Crawford AC, Fettiplace R (1980) The frequency selectivity of auditory nerve fibres and hair cells in the cochlea of the turtle. J Physiol (Lond) 306:79-125.
9. Crawford AC, Fettiplace R (1981) An electrical tuning mechanism in turtle cochlear hair cells. J Physiol (Lond) 312:377-412.
10. Cui J, Cox DH, Aldrich RW (1997) Intrinsic voltage dependence and Ca2+ regulation of mslo large conductance Ca-activated K+ channels. J Gen Physiol 109:647-673.
11. Dworetzky SI, Boissard CG, Lum-Ragan JT, McKay MC, Post-Munson DJ, Trojnacki JT, Chang CP, Gribkoff VK (1996) Phenotypic alteration of a human BK (hSlo) channel by hSlo beta subunit coexpression: changes in blocker sensitivity, activation/relaxation and inactivation kinetics, and protein kinase A modulation. J Neurosci 16:4543-4550.
12. Fettiplace R, Fuchs PA (1999) Mechanisms of hair cell tuning. Annu Rev Physiol 61:809-834.
13. Fuchs PA, Evans MG (1990) Potassium currents in hair cells isolated from the cochlea of the chick. J Physiol (Lond) 429:529-551.
14. Fuchs PA, Nagai T, Evans MG (1988) Electrical tuning in hair cells isolated from the chick cochlea. J Neurosci 8:2460-2467.
15. Gummer AW, Smolders JW, Klinke R (1987) Basilar membrane motion in the pigeon measured with the Mossbauer technique. Hear Res 29:63-92.
16. Hudspeth AJ, Lewis RS (1988) Kinetic analysis of voltage- and ion-dependent conductances in saccular hair cells of the bull-frog, Rana catesbeiana. J Physiol (Lond) 400:237-274.
17. Issa NP, Hudspeth AJ (1994) Clustering of Ca2+ channels and Ca(2+)-activated K+ channels at fluorescently labeled presynaptic active zones of hair cells. Proc Natl Acad Sci USA 91:7578-7582.
18. Jiang GJ, Zidanic M, Michaels RL, Michael TH, Griguer C, Fuchs PA (1997) CSlo encodes calcium-activated potassium channels in the chick's cochlea. Proc R Soc Lond B Biol Sci 264:731-737.
19. Jones EM, Laus C, Fettiplace R (1998) Identification of Ca(2+)-activated K+ channel splice variants and their distribution in the turtle cochlea. Proc R Soc Lond B Biol Sci 265:685-692.
20. Jones EM, Gray-Keller M, Fettiplace R (1999) The role of Ca2+-activated K+ channel spliced variants in the tonotopic organization of the turtle cochlea. J Physiol (Lond) 518:653-665.
21. Jones SM, Jones TA (1995) The tonotopic map in the embryonic chicken cochlea. Hear Res 82:149-157.
22. Knaus HG, Folander K, Garcia-Calvo M, Garcia ML, Kaczorowski GJ, Smith M, Swanson R (1994) Primary sequence and immunological characterization of beta-subunit of high conductance Ca(2+)-activated K+ channel from smooth muscle. J Biol Chem 269:17274-17278.
23. Lustig L, Hiel H, Fuchs PA (1999) Vestibular hair cells of the chick express the nicotinic acctylcholine receptor subunit α9. J Vestib Res 9:359-367.
24. Manley GA, Brix J, Kaiser A (1987) Developmental stability of the tonotopic organization of the chick's basilar papilla. Science 237:655-656.
25. Marrion NV, Tavalin SJ (1998) Selective activation of Ca2+-activated K+ channels by co-localized Ca2+ channels in hippocampal neurons. Nature 395:900-905.
26. McManus OB, Helms LM, Pallanck L, Ganetzky B, Swanson R, Leonard RJ (1995) Functional role of the beta subunit of high conductance calcium-activated potassium channels. Neuron 14:645-650.
27. Meera P, Wallner M, Jiang Z, Toro L (1996) A calcium switch for the functional coupling between alpha (hslo) and beta subunits (Kv,cabeta) of maxi K channels. FEBS Lett 385:127-128.
28. Michael TH, Ramanathan K, Jones EMC, Art JJ, Fettiplace R, Fuchs PA (1997) Functional expression of cochlear slo potassium channels in HEK 293 cells and Xenopus oocytes. Biophys J 72:A352.
29. Navaratnam DS, Bell TJ, Tu TD, Cohen EL, Oberholtzer JC (1997) Differential distribution of Ca2+-activated K+ channel splice variants among hair cells along the tonotopic axis of the chick cochlea. Neuron 19:1077-1085.
30. 2+-activated potassium channels by retaining the gating in the bursting states. J Gen Physiol 113:425-440.
31. Oberst C, Weiskirchen R, Hartl M, Bister K (1997) Suppression in transformed avian fibroblasts of a gene (CO6) encoding a membrane protein related to mammalian potassium channel regulatory subunits. Oncogene 14:1109-1116.
32. Ramanathan K, Michael TH, Jiang G, Hiel H, Fuchs PA (1999) A molecular mechanism for electrical tuning of cochlear hair cells. Science 283:215-217.
33. Roberts WM, Jacobs RA, Hudspeth AJ (1990) Colocalization of ion channels involved in frequency selectivity and synaptic transmission at presynaptic active zones of hair cells. J Neurosci 10:3664-3684.
34. Robitaille R, Adler EM, Charlton MP (1993) Calcium channels and calcium-gated potassium channels at the frog neuromuscular junction. J Physiol (Paris) 87:15-24.
35. Rosenblatt KP, Sun ZP, Heller S, Hudspeth AJ (1997) Distribution of Ca2+-activated K+ channel isoforms along the tonotopic gradient of the chicken's cochlea. Neuron 19:1061-1075.
36. Saito M, Nelson C, Salkoff L, Lingle CJ (1997) A cysteine-rich domain defined by a novel exon in a slo variant in rat adrenal chromaffin cells and PC12 cells. J Biol Chem 272:11710-11717.
37. Schermuly L, Klinke R (1985) Change of characteristic frequency of pigeon primary auditory afferents with temperature. J Comp Physiol 156:209-211.
38. Schreiber M, Salkoff L (1997) A novel calcium-sensing domain in the BK channel. Biophys J 73:1355-1363.
39. Schreiber M, Yuan A, Salkoff L (1999) Transplantable sites confer calcium sensitivity to BK channels. Nat Neurosci 2:416-421.
40. Sonderegger C (1998) Conditional cell transformation by a doxycycline-controlled v-myc allele. PhD thesis, Institute of Biochemistry, University of Innsbruck.
41. Tseng-Crank J, Foster CD, Krause JD, Mertz R, Godinot N, DiChiara TJ, Reinhart PH (1994) Cloning, expression, and distribution of functionally distinct Ca(2+)-activated K+ channel isoforms from human brain. Neuron 13:1315-1330.
42. Vogalis F, Vincent T, Qureshi I, Schmalz F, Ward MW, Sanders KM, Horowitz B (1996) Cloning and expression of the large-conductance Ca(2+)-activated K+ channel from colonie smooth muscle. Am J Physiol 271:G629-639.
43. Wallner M, Meera P, Toro L (1996) Determinant for beta-subunit regulation in high-conductance voltage-activated and Ca(2+)-sensitive K+ channels: an additional transmembrane region at the N terminus. Proc Natl Acad Sci USA 93:14922-14927.
44. + channels: a transmembrane β-subunit homolog. Proc Natl Acad Sci USA 96:4137-4142.
45. Wei A, Solaro C, Lingle C, Salkoff L (1994) Calcium sensitivity of BK-type KCa channels determined by a separable domain. Neuron 13:671-681.
46. Wu YC, Art JJ, Goodman MB, Fettiplace R (1995) A kinetic description of the calcium-activated potassium channel and its application to electrical tuning of hair cells. Prog Biophys Mol Biol 63:131-158.
47. Wu YC, Fettiplace R (1996) A developmental model for generating frequency maps in the reptilian and avian cochless. Biophys J 70:2557-2570.