The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation

Development

Volumn 122, Issue 12, 1996, Pages 4179-4188

  Stennard, Fiona ^b   Carnac, Gilles ^b   Gurdon, J B ^a,b  

^a WELLCOME CRC INSTITUTE   (United Kingdom)

^b NONE

Author keywords

Antipodean; bFGF; Brachyury; Differential display; Endoderm; Eomesodermin; Localised mRNA; Maternal determinant; Mesoderm induction; T box; TGF ; Xenopus

Indexed keywords

ACTIVIN; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; ECTODERM; EMBRYO; FEMALE; GENE ACTIVATION; GENE EXPRESSION; GENE INDUCTION; MESODERM; MULTIGENE FAMILY; NONHUMAN; NOTOCHORD; PRIORITY JOURNAL; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; CELL COMPARTMENTATION; CLONING, MOLECULAR; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; EMBRYONIC DEVELOPMENT; EMBRYONIC INDUCTION; FEMALE; FETAL PROTEINS; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MESODERM; MOLECULAR SEQUENCE DATA; OOGENESIS; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; T-BOX DOMAIN PROTEINS; TIME FACTORS; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; XENOPUS; XENOPUS PROTEINS;

EID: 0030455148     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Altschul, S. F., Gish, W., Miller, W., Myers, E. W. and Lipman, J. (1990). Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
2. Amaya, E., Musci, T. J. and Kirschner, M. W. (1991). Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66, 257-270.
3. Asashima, M., Nakano, H., Shimada, K., Kinoshita, K., Ishii, K., Shibai, H. and Ueno, N. (1990). Mesodermal induction in early amphibian embryos by activin A (erythroid differentiation factor) Roux's Arch. Dev. Biol. 198, 330-335.
4. Bollag, R. J., Siegfried, A., Cebra-Thomas, J. A., Garvey, N., Davison, E. M. and Silver, L. M. (1994). An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T-locus. Nature Genet. 7, 383-389.
5. Campbell, C., Goodrich, K., Casey, G. and Beatty, B. (1995). Cloning and mapping of a human gene (TBX2) sharing a highly conserved protein motif with the Drasuphila omb gene. Genomics 28, 255-260.
6. Carnac, G., Kodjabachian, L., Gurdon, J. B. and Lemaire, P. (1996). The homeobox gene Siamois is a target of the wnt dorsalisation pathway and triggers organiser activity in the absence of mesoderm. Development (in press).
7. Christian, J. L., McMahon, J. A., McMahon, A. P. and Moon, R. T. (1991). Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderminducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis. Development 111, 1045-1055.
8. Cornell, R. A. and Kimelman, D. (1994). Activin-mediated mesoderm induction requires FGF. Development 120, 453-462.
9. Cornell, R. A., Musci, T. J. and Kimelman, D. (1995). FGF is a prospective competence factor for early activin-type signals in Xenopus mesoderm induction. Development 121, 2429-2437.
10. Cunliffe, V. and Smith, J. C. (1992). Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue. Nature 358, 427-430.
11. Dale, L., Howes, G., Price, B. M. and Smith, J. C. (1992). Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development. Development 115, 573-585.
12. Elinson, R. P., King, M. L. and Forristall, C. (1993). Isolated vegetal cortex from Xenopus oocytes selectively retains localized mRNAs. Dev. Biol. 160, 554-562.
13. Forristall, C., Pondel, M., Chen, L. and King, M. L. (1995). Patterns of localization and cytoskeletal association of two vegetally localized RNAs, Vg1 and Xcat-2. Development 121, 201-208.
14. Green, J. B. A., New, H. V. and Smith, J. C. (1992). Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm. Cell 71, 731-739.
15. Gurdon, J. B., Brennan, S., Fairman, S. and Mohun, T. J. (1984). Transcription of muscle-specific genes in early Xenopus development: nuclear transplantation and cell dissociation. Cell 38, 691-700.
16. Gurdon, J. B., Fairman, S., Mohun, T. J. and Brennan, S. (1985a). The activation of muscle specific actin genes in Xenopus development by an induction between animal and vegetal cells of a blastula. Cell 41, 913-922.
17. Gurdon, J. B, Mohun, T. J., Fairman, S. and Brennan, S. (1985b). All components required for the eventual activation of muscle specific genes are localised in the subequatorial region of an uncleaved egg. Proc. Natl. Acad. Sci. USA 82, 139-143.
18. Gurdon, J. B. (1992). The generation of diversity and pattern in animal development. Cell 68, 185-199.
19. Gurdon, J. B., Harger, P., Mitchell, A. and Lemaire, P. (1994) Activin signalling and response to a morphogen gradient. Nature 371, 487-492.
20. Harland, R. M. (1991). In situ hybridization: an improved whole-mount method for Xenopus embryos. Methods Cell Biol. 36, 685-695.
21. Henry, G. L., Brivanlou, I. H., Kessler, D. S., Hemmati-Brivanlou, A. and Melton, D. A. (1996). TGF-β signals and a prepattern in Xenopus laevis endodermal development. Development 122, 1007-1015.
22. Hemmati-Brivanlou, A. and Harland, R. A. (1989). Expression of an engrailed-related protein is induced in the anterior neural ectoderm of early Xenopus embryos. Development 106, 611-617.
23. Hemmati-Brivanlou, A., Frank, D., Bolce, M. E., Brown, R. D., Sive, H. L. and Harland, R. M. (1990). Localization of specific mRNAs in Xenopus embryos by whole mount in situ hybridization. Development 110, 325-330.
24. Hemmati-Brivanlou, A. and Melton, D. A. (1992). A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature 359, 609-614.
25. Isaacs, H. V., Pownall, M. E. and Slack, J. M. W. (1994). eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J. 13, 4469-4481.
26. Jones, C. M., Kuehn, M. R., Hogan, B. L. M., Smith, J. C. and Wright, C. V. E. (1995). Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development 121, 3651-3662.
27. Jones, E. A. and Woodland, H. R. (1987). The development of animal cap cells in Xenopus: a measure of the start of animal cap competence to form mesoderm. Development 101, 557-563.
28. Kessler, D. S. and Melton, D. A. (1995). Induction of dorsal mesoderm by soluble mature Vg1 protein. Development 121, 2155-2164.
29. Kispert, A., Koschorz, B. and Herrmann, G. (1995). The T-protein encoded by Brachyury is a tissue specific transcription factor. EMBO J. 14, 4763-4772.
30. Kloc, M., Spohr, G. and Etkin, L. D. (1993). Translocation of repetitive RNA sequences with the germ plasm in Xenopus oocytes. Science 262, 1712-1714.
31. Ku, M. and Melton, D. A. (1993). X1wnt-11: a maternally expressed Xenopus wnt gene. Development 119, 1161-1173.
32. Lemaire, P. and Gurdon, J. B. (1994). A role for cytoplasmic determinants in mesoderm patterning: cell-autonomous activation of the goosecoid and Xwnt-8 genes along the dorsoventral axis of early Xenopus embryos. Development 120, 1191-1199.
33. Lemaire, P., Garrett, N. and Gurdon, J. B. (1995). Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis. Cell 81, 85-94.
34. Liang, P. and Pardee, A. B. (1992). Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257, 967-971.
35. Mosquera, L., Forristall, C., Zhou, Y. and King, M. L. (1993) A mRNA localized to the vegetal cortex of Xenopus oocytes encodes a protein with a nanos-like zinc linger domain. Development 117, 377-386.
36. Nieuwkoop, P. D. and Faber, J. (1967). Normal Table of Xenopus laevis (Daudin), 2nd ed. Amsterdam: North Holland.
37. Nishida, H. (1996). Vegetal cytoplasm promotes gastrulation and is responsible for specification of vegetal blastomeres in embryos of the ascidian Halocynthia roretzi. Development 122, 1271-1279.
38. Pflugfelder, G. O., Roth, H., Poeck, B., Kerscher, S., Schwartz, H., Jonschker, B. and Heisenberg, M. (1992). The lethal (1) optomotor-blind gene of Drosophila melanogaster is a major organizer of optic lobe development: isolation and characterization of the gene. Proc. Natl. Acad. Sci. USA 89, 1199-1203.
39. Rosa, F.M. (1989). Mix. 1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos. Cell 57, 965-974.
40. Ryan, K., Garrett, N., Mitchell, A. and Gurdon, J. B. (1996). Eomesodermin, a key early gene in Xenopus mesoderm differentiation. Cell, in press.
41. Schulte-Merker, S., Smith, J. C. and Dale, L. (1994). Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of BVg1 and activin: does activin play a role in mesoderm induction? EMBO J. 13, 3533-3541.
42. Schulte-Merker, S. and Smith, J. C. (1995). Mesoderm formation in response to Brachyury requires FGF signalling. Curr. Biol. 5, 62-67.
43. Slack, J. M. W. (1994). Inducing factors in Xenopus early embryos. Curr. Biol. 4, 116-126.
44. Smith, J. C., Price, B. M., Green, J. B. A., Weigel, D. and Herrmann, B. G. (1991). Expression of a Xenopus homolog of brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87.
45. Symes, K., Yaqoob, M. and Smith, J. C. (1988). Mesoderm induction in Xenopus laevis: responding cells must be in contact for mesoderm formation but suppression of epidermal differentiation can occur in single cells. Development, 104, 609-618.
46. Thompson, J. and Slack, J. M. (1992). Over-expression of fibroblast growth factors in Xenopus embryos. Mech. Dev. 38, 175-182.
47. Thomsen, G., Woolf, T., Whitman, M., Sokol, S., Vaughan, J., Vale, W. and Melton, D. A. (1990). Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell 63, 485-93.
48. Thomsen, G. H. and Melton, D. A. (1993). Processed Vg1 protein is an axial mesoderm inducer in Xenopus. Cell 74, 433-441.
49. Weeks, D. L. and Melton, D. A. (1987). A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-β. Cell 51, 861-867.
50. Wittbrodt, J. and Rosa, F. (1994). Disruption of mesoderm and axis formation in fish by ectopic expression of activin variants: the role of maternal activin. Genes Dev. 8, 1448-1462.