-
1
-
-
0027506043
-
Multiple genes for G protein-coupled receptors and their expression in lingual epithelia
-
Abe, K., Kusakabe, Y., Tanemura, K., Emori, Y. and Arai, S. (1993a) Multiple genes for G protein-coupled receptors and their expression in lingual epithelia. FEBS Lett., 316, 253-256.
-
(1993)
FEBS Lett.
, vol.316
, pp. 253-256
-
-
Abe, K.1
Kusakabe, Y.2
Tanemura, K.3
Emori, Y.4
Arai, S.5
-
2
-
-
0027298698
-
Primary structure and cell-type specific expression of a gustatory G protein-coupled receptor related to olfactory receptors
-
Abe, K., Kusakabe, Y., Tanemura, K., Emori, Y. and Arai, S. (1993b) Primary structure and cell-type specific expression of a gustatory G protein-coupled receptor related to olfactory receptors. J. Biol. Chem., 268, 12033-12039.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 12033-12039
-
-
Abe, K.1
Kusakabe, Y.2
Tanemura, K.3
Emori, Y.4
Arai, S.5
-
3
-
-
85035172267
-
-
ADDAD (Association pour le Développement et la Diffusion de l'Analyse des Données), 4 Place Jussieu, 75005 Paris, France
-
ADDAD (Association pour le Développement et la Diffusion de l'Analyse des Données), 4 Place Jussieu, 75005 Paris, France.
-
-
-
-
4
-
-
0029623184
-
Computational methods to predict binding free energy in ligand-receptor complexes
-
Ajay and Murcko, M.A. (1995) Computational methods to predict binding free energy in ligand-receptor complexes. J. Med. Chem., 38, 4953-4967.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4953-4967
-
-
Ajay1
Murcko, M.A.2
-
6
-
-
0001635093
-
The Cambridge Crystallographic Data Centre: Computer-based search, retrieval, analysis and display of information
-
Allen, F.H., Bellard, S., Brice, M.D., Cartwright, B.A., Doubleday, A., Higgs, H., Hummelink, T., Hummelink-Peters, B.G., Kennard, O., Motherwell, W.D.S., Rodgers, J.R. and Watson, D.G. (1979) The Cambridge Crystallographic Data Centre: computer-based search, retrieval, analysis and display of information. Acta Crystallogr., B35, 2331-2339.
-
(1979)
Acta Crystallogr.
, vol.B35
, pp. 2331-2339
-
-
Allen, F.H.1
Bellard, S.2
Brice, M.D.3
Cartwright, B.A.4
Doubleday, A.5
Higgs, H.6
Hummelink, T.7
Hummelink-Peters, B.G.8
Kennard, O.9
Motherwell, W.D.S.10
Rodgers, J.R.11
Watson, D.G.12
-
7
-
-
11644328584
-
Systematic analysis of structural data as a research technique in organic chemistry
-
Allen, F.H., Kennard, O. and Taylor, R. (1983) Systematic analysis of structural data as a research technique in organic chemistry. Accts. Chem. Res., 16, 146-153.
-
(1983)
Accts. Chem. Res.
, vol.16
, pp. 146-153
-
-
Allen, F.H.1
Kennard, O.2
Taylor, R.3
-
9
-
-
0025737742
-
Design of enzyme inhibitors using iterative protein crystallographic analysis
-
Appelt, K., Bacquet, R.J., Bartlett, C.A., Booth, C.L.J., Freer, S.T., Fuhry, M.A.M., Gehring, M.R., Herrmann, S.M., Howland, E.F., Janson, C.A., Jones, T.R., Kan, C.-C., Kathardekar, V., Lewis, K.K., Marzoni, G.P., Matthews, D.A., Mohr, C., Moomaw, E.W., Morse, C.A., Oatley, S.J., Ogden, R.C., Reddy, M.R., Reich, S.H., Schoettlin, W.S., Smith, W.W., Varney, M.D., Villafranca, J.E., Ward, R.W., Webber, S., Webber, S.E., Welsh, K.M. and White, J. (1991) Design of enzyme inhibitors using iterative protein crystallographic analysis. J. Med. Chem., 34, 1925-1934.
-
(1991)
J. Med. Chem.
, vol.34
, pp. 1925-1934
-
-
Appelt, K.1
Bacquet, R.J.2
Bartlett, C.A.3
Booth, C.L.J.4
Freer, S.T.5
Fuhry, M.A.M.6
Gehring, M.R.7
Herrmann, S.M.8
Howland, E.F.9
Janson, C.A.10
Jones, T.R.11
Kan, C.-C.12
Kathardekar, V.13
Lewis, K.K.14
Marzoni, G.P.15
Matthews, D.A.16
Mohr, C.17
Moomaw, E.W.18
Morse, C.A.19
Oatley, S.J.20
Ogden, R.C.21
Reddy, M.R.22
Reich, S.H.23
Schoettlin, W.S.24
Smith, W.W.25
Varney, M.D.26
Villafranca, J.E.27
Ward, R.W.28
Webber, S.29
Webber, S.E.30
Welsh, K.M.31
White, J.32
more..
-
10
-
-
0017411710
-
The Protein Data Bank: A computer-based archival file for macromolecular structures
-
Bernstein, F.C., Koetzle, T.F., Williams, G.J., Meyer, E.E., Jr, Brice, M.D., Rodgers, J.R., Kennard, O., Shimanouchi, T. and Tasumi, M. (1977) The Protein Data Bank: a computer-based archival file for macromolecular structures. J. Mol. Biol., 112, 535-542.
-
(1977)
J. Mol. Biol.
, vol.112
, pp. 535-542
-
-
Bernstein, F.C.1
Koetzle, T.F.2
Williams, G.J.3
Meyer Jr., E.E.4
Brice, M.D.5
Rodgers, J.R.6
Kennard, O.7
Shimanouchi, T.8
Tasumi, M.9
-
11
-
-
0016995441
-
Structural relationships of sugars to taste
-
Birch, G.G. (1976) Structural relationships of sugars to taste. CRC Crit. Rev. Food Sci. Nutr., 8, 57-95.
-
(1976)
CRC Crit. Rev. Food Sci. Nutr.
, vol.8
, pp. 57-95
-
-
Birch, G.G.1
-
12
-
-
0003061163
-
Genetics of sensory thresholds: Individual taste reactions for different substances
-
Blakeslee, A.F. and Salmon, T.N. (1935) Genetics of sensory thresholds: individual taste reactions for different substances. Proc. Natl. Acad. Sci. USA, 21, 84-90.
-
(1935)
Proc. Natl. Acad. Sci. USA
, vol.21
, pp. 84-90
-
-
Blakeslee, A.F.1
Salmon, T.N.2
-
13
-
-
0026813925
-
The computer program LUDI: A new method for the de novo design of enzyme inhibitors
-
Böhm, H.-J. (1992a) The computer program LUDI: a new method for the de novo design of enzyme inhibitors. J. Comput.-Aided Mol. Des., 6, 61-78.
-
(1992)
J. Comput.-Aided Mol. Des.
, vol.6
, pp. 61-78
-
-
Böhm, H.-J.1
-
14
-
-
0027027467
-
LUDI: Rule-based automatic design of new substituents for enzyme inhibitor leads
-
Böhm, H.-J. (1992b) LUDI: rule-based automatic design of new substituents for enzyme inhibitor leads. J. Comput.-Aided Mol. Des., 6, 593-606.
-
(1992)
J. Comput.-Aided Mol. Des.
, vol.6
, pp. 593-606
-
-
Böhm, H.-J.1
-
15
-
-
0028454828
-
The development of a simple empirical scoring function to estimate the binding constant for a protein-ligand complex of known three-dimensional structure
-
Böhm, H.-J. (1994) The development of a simple empirical scoring function to estimate the binding constant for a protein-ligand complex of known three-dimensional structure. J. Comput.-Aided Mol. Des., 8, 243-256.
-
(1994)
J. Comput.-Aided Mol. Des.
, vol.8
, pp. 243-256
-
-
Böhm, H.-J.1
-
16
-
-
0024566942
-
New hydrogen-bond potentials for use in determining energetically favorable binding sites on molecules of known structure
-
Boobbyer, D.N.A., Goodford, P.J., McWhinnie, P.M. and Wade, R.C. (1989) New hydrogen-bond potentials for use in determining energetically favorable binding sites on molecules of known structure. J. Med. Chem., 32, 1083-1094.
-
(1989)
J. Med. Chem.
, vol.32
, pp. 1083-1094
-
-
Boobbyer, D.N.A.1
Goodford, P.J.2
McWhinnie, P.M.3
Wade, R.C.4
-
17
-
-
0028073739
-
Signal recognition and transduction in olfactory neurons
-
Breer, H., Raming, K. and Krieger, J. (1994) Signal recognition and transduction in olfactory neurons. Biochim. Biophys. Acta, 1224, 277-287.
-
(1994)
Biochim. Biophys. Acta
, vol.1224
, pp. 277-287
-
-
Breer, H.1
Raming, K.2
Krieger, J.3
-
18
-
-
0025825726
-
A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
-
Buck, L. and Axel, R. (1991) A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell, 65, 175-187.
-
(1991)
Cell
, vol.65
, pp. 175-187
-
-
Buck, L.1
Axel, R.2
-
20
-
-
0003626507
-
-
Cambridge Crystallographic Data Centre (CCDC), University Chemical Laboratory, Lensfield Road, Cambridge CB2 1EW, UK
-
Cambridge Structural Database (CSD) Cambridge Crystallographic Data Centre (CCDC), University Chemical Laboratory, Lensfield Road, Cambridge CB2 1EW, UK.
-
Cambridge Structural Database (CSD)
-
-
-
21
-
-
0027512202
-
The taste system of the channel catfish: From biophysics to behavior
-
Caprio, J., Brand, J.G., Teeter, J.H., Valentincic, T., Kalinoski, D.L., Kohbara, J., Kumazawa, T. and Wegert, S. (1993) The taste system of the channel catfish: from biophysics to behavior. Trends Neurosci., 16, 192-197.
-
(1993)
Trends Neurosci.
, vol.16
, pp. 192-197
-
-
Caprio, J.1
Brand, J.G.2
Teeter, J.H.3
Valentincic, T.4
Kalinoski, D.L.5
Kohbara, J.6
Kumazawa, T.7
Wegert, S.8
-
22
-
-
0016352763
-
Hydrophobic bonding and accessible surface area in proteins
-
Chothia, C. (1974) Hydrophobic bonding and accessible surface area in proteins. Nature, 248, 338-339.
-
(1974)
Nature
, vol.248
, pp. 338-339
-
-
Chothia, C.1
-
23
-
-
0010365987
-
-
The Quantum Chemistry Program Exchange, Indiana University, Bloomington, IN 47405, USA
-
Connolly, M.L. (1981) Molecular Surface Program (QCPE program no. 429). The Quantum Chemistry Program Exchange, Indiana University, Bloomington, IN 47405, USA.
-
(1981)
Molecular Surface Program (QCPE Program No. 429)
-
-
Connolly, M.L.1
-
24
-
-
0000538815
-
Analytical molecular surface calculation
-
Connolly, M.L. (1983) Analytical molecular surface calculation. J. Appl. Crystallogr., 16, 548-558.
-
(1983)
J. Appl. Crystallogr.
, vol.16
, pp. 548-558
-
-
Connolly, M.L.1
-
25
-
-
0023751431
-
Comparative Molecular Field Analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins
-
Cramer, R.D., III, Patterson, D.E. and Bunce, J.D. (1988) Comparative Molecular Field Analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins. J. Am. Chem. Soc., 110, 5959-5967.
-
(1988)
J. Am. Chem. Soc.
, vol.110
, pp. 5959-5967
-
-
Cramer III, R.D.1
Patterson, D.E.2
Bunce, J.D.3
-
26
-
-
0003146832
-
The developing practice of comparative molecular field analysis
-
Kubinyi, H. (ed.), ESCOM, Leiden
-
Cramer, R.D., III, DePreist, S.A., Patterson, D.E. and Hecht, P. (1993) The developing practice of comparative molecular field analysis. In Kubinyi, H. (ed.), 3D QSAR in Drug Design: Theory, Methods and Applications. ESCOM, Leiden, pp. 443-485.
-
(1993)
3D QSAR in Drug Design: Theory, Methods and Applications
, pp. 443-485
-
-
Cramer III, R.D.1
DePreist, S.A.2
Patterson, D.E.3
Hecht, P.4
-
27
-
-
0022430162
-
The search for functional correspondences in molecular structure between two dissimilar molecules
-
Danziger, D.J. and Dean, P.M. (1985) The search for functional correspondences in molecular structure between two dissimilar molecules. J. Theor. Biol., 116, 215-224.
-
(1985)
J. Theor. Biol.
, vol.116
, pp. 215-224
-
-
Danziger, D.J.1
Dean, P.M.2
-
28
-
-
0642295351
-
Molecular recognition: Blind-searching for regions of strong structural match on the surfaces of two dissimilar molecules
-
Dean, P.M., Callow, P. and Chau, P.-L. (1988) Molecular recognition: blind-searching for regions of strong structural match on the surfaces of two dissimilar molecules. J. Mol. Graphics, 6, 28-34.
-
(1988)
J. Mol. Graphics
, vol.6
, pp. 28-34
-
-
Dean, P.M.1
Callow, P.2
Chau, P.-L.3
-
29
-
-
24444468650
-
Ground states of molecules. 38. The MNDO method. Approximations and parameters
-
Dewar, M.J.S. and Thiel, W. (1977) Ground states of molecules. 38. The MNDO method. Approximations and parameters. J. Am. Chem. Soc., 99, 4899-4907.
-
(1977)
J. Am. Chem. Soc.
, vol.99
, pp. 4899-4907
-
-
Dewar, M.J.S.1
Thiel, W.2
-
30
-
-
0842341771
-
AM1: A new general purpose quantum mechanical molecular model
-
Dewar, M.J.S., Zoebisch, E.G., Healy, E.F. and Stewart, J.J.P. (1985) AM1: a new general purpose quantum mechanical molecular model. J. Am. Chem. Soc., 107, 3902-3909.
-
(1985)
J. Am. Chem. Soc.
, vol.107
, pp. 3902-3909
-
-
Dewar, M.J.S.1
Zoebisch, E.G.2
Healy, E.F.3
Stewart, J.J.P.4
-
31
-
-
0005552443
-
A comparison of neural and psychophysical responses to taste stimuli in man
-
Diamant, H., Oakley, B., Ström, L., Wells, C. and Zotterman, Y. (1965) A comparison of neural and psychophysical responses to taste stimuli in man. Acta Physiol. Scand., 64, 67-74.
-
(1965)
Acta Physiol. Scand.
, vol.64
, pp. 67-74
-
-
Diamant, H.1
Oakley, B.2
Ström, L.3
Wells, C.4
Zotterman, Y.5
-
32
-
-
0003222935
-
Physiology of the sweet taste
-
Ottoson, D. (ed.), Springer-Verlag, Berlin
-
Faurion, A. (1987) Physiology of the sweet taste. In Ottoson, D. (ed.), Progress in Sensory Physiology 8. Springer-Verlag, Berlin, pp. 129-201.
-
(1987)
Progress in Sensory Physiology 8
, pp. 129-201
-
-
Faurion, A.1
-
33
-
-
0006322585
-
The physiology of sweet taste and molecular receptors
-
Mathlouthi, M. and Birch, G.G. (eds), Elsevier, Amsterdam
-
Faurion, A. (1993) The physiology of sweet taste and molecular receptors. In Mathlouthi, M. and Birch, G.G. (eds), Sweet Taste Chemoreception. Elsevier, Amsterdam, pp. 291-316.
-
(1993)
Sweet Taste Chemoreception
, pp. 291-316
-
-
Faurion, A.1
-
34
-
-
0344621153
-
Sweet taste receptor mechanisms
-
Birch, G.G. and Parker, K.J. (eds), Applied Science, London
-
Faurion, A. and Mac Leod, P. (1982) Sweet taste receptor mechanisms. In Birch, G.G. and Parker, K.J. (eds), Nutritive Sweeteners. Applied Science, London, pp. 247-273.
-
(1982)
Nutritive Sweeteners
, pp. 247-273
-
-
Faurion, A.1
Mac Leod, P.2
-
35
-
-
0025236564
-
Taste as a highly discriminative system: A hamster intrapapillar single unit study with 18 compounds
-
Faurion A. and Vayssettes-Courchay C. (1990) Taste as a highly discriminative system: a hamster intrapapillar single unit study with 18 compounds. Brain Res., 512, 317-332.
-
(1990)
Brain Res.
, vol.512
, pp. 317-332
-
-
Faurion, A.1
Vayssettes-Courchay, C.2
-
36
-
-
0019219880
-
Sweet taste involves several distinct receptor mechanisms
-
Faurion, A., Saito, S. and Mac Leod, P. (1980) Sweet taste involves several distinct receptor mechanisms. Chem. Senses, 5, 107-121.
-
(1980)
Chem. Senses
, vol.5
, pp. 107-121
-
-
Faurion, A.1
Saito, S.2
Mac Leod, P.3
-
37
-
-
0021828928
-
Hydrogen bonding and biological specificity analysed by protein engineering
-
Fersht, A.R., Shi, J.-P., Knill-Jones, J., Lowe, D.M., Wilkinson, A.J., Blow, D.M., Brick, P., Carter, P., Waye, M.M.Y. and Winter, G. (1985) Hydrogen bonding and biological specificity analysed by protein engineering. Nature, 314, 235-238.
-
(1985)
Nature
, vol.314
, pp. 235-238
-
-
Fersht, A.R.1
Shi, J.-P.2
Knill-Jones, J.3
Lowe, D.M.4
Wilkinson, A.J.5
Blow, D.M.6
Brick, P.7
Carter, P.8
Waye, M.M.Y.9
Winter, G.10
-
39
-
-
9444225324
-
Molecular modelling approach to the structure of taste receptor sites
-
Kurihara, K., Suzuki, N. and Ogawa, H. (eds), Springer-Verlag, Berlin
-
Froloff, N., Faurion, A. and Mac Leod, P. (1994) Molecular modelling approach to the structure of taste receptor sites. In Kurihara, K., Suzuki, N. and Ogawa, H. (eds), Olfaction and Taste XI. Springer-Verlag, Berlin, p. 88.
-
(1994)
Olfaction and Taste XI
, pp. 88
-
-
Froloff, N.1
Faurion, A.2
Mac Leod, P.3
-
40
-
-
9444234821
-
Molecular modelling approach to the structure of taste receptor sites
-
abstract ECRO XI
-
Froloff, N., Faurion, A. and Mac Leod, P. (1995) Molecular modelling approach to the structure of taste receptor sites. Chem. Senses, 20, 82 (abstract ECRO XI).
-
(1995)
Chem. Senses
, vol.20
, pp. 82
-
-
Froloff, N.1
Faurion, A.2
Mac Leod, P.3
-
41
-
-
9444245597
-
Spectrophotometric determination of basicity constants. Part III. Phenylureas
-
Giffney, C.J. and O'Connor, C.J. (1975) Spectrophotometric determination of basicity constants. Part III. Phenylureas. J. Chem. Soc. Perkin Trans. II, 1206-1209.
-
(1975)
J. Chem. Soc. Perkin Trans. II
, pp. 1206-1209
-
-
Giffney, C.J.1
O'Connor, C.J.2
-
42
-
-
0009584429
-
Molecules and molecular crystals
-
Giacovazzo, C. (ed.), Oxford University Press, Oxford
-
Gilli, G. (1992) Molecules and molecular crystals. In Giacovazzo, C. (ed.), Fundamentals of Crystallography. Oxford University Press, Oxford, pp. 465-534.
-
(1992)
Fundamentals of Crystallography
, pp. 465-534
-
-
Gilli, G.1
-
43
-
-
0021871375
-
A computational procedure for determining energetically favorable binding sites on biologically important macromolecules
-
Goodford, P.J. (1985) A computational procedure for determining energetically favorable binding sites on biologically important macromolecules. J. Med. Chem., 28, 849-857.
-
(1985)
J. Med. Chem.
, vol.28
, pp. 849-857
-
-
Goodford, P.J.1
-
44
-
-
0025135112
-
Automated docking of substrates to proteins by simulated annealing
-
Goodsell, D.S. and Olson, A.J. (1990) Automated docking of substrates to proteins by simulated annealing. Proteins, 8, 195-202.
-
(1990)
Proteins
, vol.8
, pp. 195-202
-
-
Goodsell, D.S.1
Olson, A.J.2
-
45
-
-
0028929583
-
Free energy balance in protein folding
-
Honig, B. and Yang, A.-S. (1995) Free energy balance in protein folding. Adv. Protein Chem., 46, 27-58.
-
(1995)
Adv. Protein Chem.
, vol.46
, pp. 27-58
-
-
Honig, B.1
Yang, A.-S.2
-
46
-
-
0029019869
-
A continuum model for protein-protein interactions: Application to the docking problem
-
Jackson, R.M. and Sternberg, M.J.E. (1995) A continuum model for protein-protein interactions: application to the docking problem. J. Mol. Biol., 250, 258-275.
-
(1995)
J. Mol. Biol.
, vol.250
, pp. 258-275
-
-
Jackson, R.M.1
Sternberg, M.J.E.2
-
47
-
-
0027930292
-
Compass: Predicting biological activities from molecular surface properties. Performance comparisons on a steroid benchmark
-
Jain, A.N., Koile, K. and Chapman, D. (1994) Compass: predicting biological activities from molecular surface properties. Performance comparisons on a steroid benchmark. J. Med. Chem., 37, 2315-2327.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 2315-2327
-
-
Jain, A.N.1
Koile, K.2
Chapman, D.3
-
48
-
-
0028861437
-
Elusive affinities
-
Janin, J. (1995) Elusive affinities. Proteins, 21, 30-39.
-
(1995)
Proteins
, vol.21
, pp. 30-39
-
-
Janin, J.1
-
49
-
-
0026425975
-
Rusting of the lock and key model for protein-ligand binding
-
Jorgensen, W.L. (1991) Rusting of the lock and key model for protein-ligand binding. Science, 254, 954-955.
-
(1991)
Science
, vol.254
, pp. 954-955
-
-
Jorgensen, W.L.1
-
50
-
-
0008863560
-
Some factors in the interpretation of protein denaturation
-
Kauzmann, W. (1959) Some factors in the interpretation of protein denaturation. Adv. Protein Chem., 14, 1-63.
-
(1959)
Adv. Protein Chem.
, vol.14
, pp. 1-63
-
-
Kauzmann, W.1
-
51
-
-
0015403701
-
A molecular theory of sweet taste
-
Kier, L.B. (1972) A molecular theory of sweet taste. J. Pharmacol. Sci., 61, 1394-1397.
-
(1972)
J. Pharmacol. Sci.
, vol.61
, pp. 1394-1397
-
-
Kier, L.B.1
-
53
-
-
0027139338
-
Affinity and specificity of serine endopeptidase-protein inhibitor interactions. Empirical free energy calculations based on X-ray crystallographic structures
-
Krystek, S., Stouch, T. and Novotny, J. (1993) Affinity and specificity of serine endopeptidase-protein inhibitor interactions. Empirical free energy calculations based on X-ray crystallographic structures. J. Mol. Biol., 234, 661-679.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 661-679
-
-
Krystek, S.1
Stouch, T.2
Novotny, J.3
-
54
-
-
0025241890
-
MAD, un programme français de modélisation moléculaire ouvert
-
Lahana, R. (1990) MAD, un programme français de modélisation moléculaire ouvert. Le Technoscope de Biofutur, no. 34, 14-15.
-
(1990)
Le Technoscope de Biofutur
, vol.34
, pp. 14-15
-
-
Lahana, R.1
-
55
-
-
0001263817
-
Olfactory receptors
-
Lancet, D. and Ben-Arie, N. (1993) Olfactory receptors. Curr. Biol., 3, 668-674.
-
(1993)
Curr. Biol.
, vol.3
, pp. 668-674
-
-
Lancet, D.1
Ben-Arie, N.2
-
56
-
-
0026570977
-
CLIX: A search algorithm for finding novel ligands capable of binding proteins of known three-dimensional structure
-
Lawrence, M.C. and Davis, P.C. (1992) CLIX: a search algorithm for finding novel ligands capable of binding proteins of known three-dimensional structure. Proteins, 12, 31-41.
-
(1992)
Proteins
, vol.12
, pp. 31-41
-
-
Lawrence, M.C.1
Davis, P.C.2
-
57
-
-
0015222647
-
The interpretation of protein structures: Estimation of static accessibility
-
Lee, B. and Richards, F.M. (1971) The interpretation of protein structures: estimation of static accessibility. J. Mol. Biol., 55, 379-400.
-
(1971)
J. Mol. Biol.
, vol.55
, pp. 379-400
-
-
Lee, B.1
Richards, F.M.2
-
58
-
-
0023472974
-
The chemistry and biochemistry of the sweetness of sugars
-
Tipson, R.S. and Horton, D. (eds), Academic Press, San Diego, CA
-
Lee, C.-K. (1987) The chemistry and biochemistry of the sweetness of sugars. In Tipson, R.S. and Horton, D. (eds), Advances in Carbohydrate Chemistry and Biochemistry. Academic Press, San Diego, CA, Vol. 45, pp. 199-351.
-
(1987)
Advances in Carbohydrate Chemistry and Biochemistry
, vol.45
, pp. 199-351
-
-
Lee, C.-K.1
-
59
-
-
0024503067
-
Automated site-directed drug design: The concept of spacer skeletons for primary structure generation
-
Lewis, R.A. and Dean, P.M. (1989a) Automated site-directed drug design: the concept of spacer skeletons for primary structure generation. Proc. R. Soc. Lond. B Biol. Sci., 236, 125-140.
-
(1989)
Proc. R. Soc. Lond. B Biol. Sci.
, vol.236
, pp. 125-140
-
-
Lewis, R.A.1
Dean, P.M.2
-
60
-
-
0024501968
-
Automated site-directed drug design: The formation of molecular templates in primary structure generation
-
Lewis, R.A. and Dean, P.M. (1989b) Automated site-directed drug design: the formation of molecular templates in primary structure generation. Proc. R. Soc. Lond. B Biol. Sci., 236, 141-162.
-
(1989)
Proc. R. Soc. Lond. B Biol. Sci.
, vol.236
, pp. 141-162
-
-
Lewis, R.A.1
Dean, P.M.2
-
61
-
-
0344621146
-
Cross-adaptation taste studies in the human
-
Abstract ECRO XI
-
Lloret E., Martinez, J.-M. and Faurion, A. (1995) Cross-adaptation taste studies in the human. Chem. Senses, 20, 144 (Abstract ECRO XI).
-
(1995)
Chem. Senses
, vol.20
, pp. 144
-
-
Lloret, E.1
Martinez, J.-M.2
Faurion, A.3
-
62
-
-
85035180226
-
-
MAD (Molecular Advanced Design). Oxford Molecular Ltd, The Magdalen Centre, Oxford Science Park, Oxford OX4 4GA, UK
-
MAD (Molecular Advanced Design). Oxford Molecular Ltd, The Magdalen Centre, Oxford Science Park, Oxford OX4 4GA, UK.
-
-
-
-
63
-
-
0027548454
-
A fast new approach to pharmacophore mapping and its application to dopaminergic and benzodiazepine agonists
-
Martin, Y.C., Bures, M.G., Danaher, E.A., DeLazzer, J., Lico, I. and Pavlik, P.A. (1993) A fast new approach to pharmacophore mapping and its application to dopaminergic and benzodiazepine agonists. J. Comput.-Aided Mol. Des., 7, 83-102.
-
(1993)
J. Comput.-Aided Mol. Des.
, vol.7
, pp. 83-102
-
-
Martin, Y.C.1
Bures, M.G.2
Danaher, E.A.3
DeLazzer, J.4
Lico, I.5
Pavlik, P.A.6
-
64
-
-
0027323362
-
Identification of novel members of G-protein coupled receptor superfamily expressed in bovine taste tissue
-
Matsuoka, I., Mori, T., Aoki, J., Sato, T. and Kurihara, K. (1993) Identification of novel members of G-protein coupled receptor superfamily expressed in bovine taste tissue. Biochem. Biophys. Res. Commun., 194, 504-511.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.194
, pp. 504-511
-
-
Matsuoka, I.1
Mori, T.2
Aoki, J.3
Sato, T.4
Kurihara, K.5
-
65
-
-
5744249209
-
Equation of state calculations by fast computing machines
-
Metropolis, N., Rosenbluth, A.W., Rosenbluth, M.N., Teller, A.H. and Teller, E. (1953) Equation of state calculations by fast computing machines. J. Chem. Phys., 21, 1087-1092.
-
(1953)
J. Chem. Phys.
, vol.21
, pp. 1087-1092
-
-
Metropolis, N.1
Rosenbluth, A.W.2
Rosenbluth, M.N.3
Teller, A.H.4
Teller, E.5
-
66
-
-
85035182354
-
-
MOPAC. The Quantum Chemistry Program Exchange, Indiana University, Bloomington, IN 47405, USA
-
MOPAC. The Quantum Chemistry Program Exchange, Indiana University, Bloomington, IN 47405, USA.
-
-
-
-
67
-
-
85035181153
-
-
NAG (Numerical Algorithms Group Ltd), Mayfield House, 256 Banbury Road, Oxford OX2 7DE, UK
-
NAG (Numerical Algorithms Group Ltd), Mayfield House, 256 Banbury Road, Oxford OX2 7DE, UK.
-
-
-
-
68
-
-
0000238336
-
A simplex method for function minimisation
-
Neider, J.A. and Mead, R. (1965) A simplex method for function minimisation. Comput. J., 7, 308-313.
-
(1965)
Comput. J.
, vol.7
, pp. 308-313
-
-
Neider, J.A.1
Mead, R.2
-
69
-
-
0027278101
-
Binding-site modeling of the muscarinic m1 receptor: A combination of homology-based and indirect approaches
-
Nordvall, G. and Hacksell, U. (1993) Binding-site modeling of the muscarinic m1 receptor: a combination of homology-based and indirect approaches. J. Med. Chem., 36, 967-976.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 967-976
-
-
Nordvall, G.1
Hacksell, U.2
-
70
-
-
0021272299
-
Human saliva and taste responses to acids varying in anions, titratable acidity, and pH
-
Norris, M.B., Noble, A.C. and Pangborn, R.M. (1984) Human saliva and taste responses to acids varying in anions, titratable acidity, and pH. Physiol. Behav., 32, 237-244.
-
(1984)
Physiol. Behav.
, vol.32
, pp. 237-244
-
-
Norris, M.B.1
Noble, A.C.2
Pangborn, R.M.3
-
71
-
-
0024362070
-
On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5
-
Novotny, J., Bruccoleri, R.E. and Saul, F.A. (1989) On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5. Biochemistry, 28, 4735-4749.
-
(1989)
Biochemistry
, vol.28
, pp. 4735-4749
-
-
Novotny, J.1
Bruccoleri, R.E.2
Saul, F.A.3
-
72
-
-
0021845642
-
Odorant-sensitive adenylate cyclase may mediate olfactory reception
-
Pace, U., Hanski, E., Salomon, Y. and Lancet, D. (1985) Odorant-sensitive adenylate cyclase may mediate olfactory reception. Nature, 316, 255-258.
-
(1985)
Nature
, vol.316
, pp. 255-258
-
-
Pace, U.1
Hanski, E.2
Salomon, Y.3
Lancet, D.4
-
73
-
-
0026147785
-
Molecular structure matching by simulated annealing. IV. Classification of atom correspondences in sets of dissimilar molecules
-
Papadopoulos, M.C. and Dean, P.M. (1991) Molecular structure matching by simulated annealing. IV. Classification of atom correspondences in sets of dissimilar molecules. J. Comput.-Aided Mol. Des., 5, 119-133.
-
(1991)
J. Comput.-Aided Mol. Des.
, vol.5
, pp. 119-133
-
-
Papadopoulos, M.C.1
Dean, P.M.2
-
75
-
-
0003474751
-
-
Cambridge University Press, Cambridge
-
Press, W.H., Flannery, B.P., Teukolsky, S.A. and Vetterling, W.T. (eds) (1986) Numerical Recipes. The Art of Scientific Computing. Cambridge University Press, Cambridge.
-
(1986)
Numerical Recipes. The Art of Scientific Computing
-
-
Press, W.H.1
Flannery, B.P.2
Teukolsky, S.A.3
Vetterling, W.T.4
-
76
-
-
0027475469
-
Cloning and expression of odorant receptors
-
Raming, K., Krieger, J., Strotmann, J., Boekhoff, I., Kubick, S., Baumstark, C. and Breer, H. (1993) Cloning and expression of odorant receptors. Nature, 361, 353-356.
-
(1993)
Nature
, vol.361
, pp. 353-356
-
-
Raming, K.1
Krieger, J.2
Strotmann, J.3
Boekhoff, I.4
Kubick, S.5
Baumstark, C.6
Breer, H.7
-
77
-
-
0017429069
-
Areas, volumes, packing and protein structure
-
Richards, F. M. (1977) Areas, volumes, packing and protein structure. Annu. Rev. Biophys. Bioengng, 6, 151-176.
-
(1977)
Annu. Rev. Biophys. Bioengng
, vol.6
, pp. 151-176
-
-
Richards, F.M.1
-
78
-
-
0023202093
-
Taste receptor proteins
-
Sato, M. (1987) Taste receptor proteins. Chem. Senses, 12, 277-283.
-
(1987)
Chem. Senses
, vol.12
, pp. 277-283
-
-
Sato, M.1
-
80
-
-
0019409072
-
Multiple receptor sites mediate sweetness: Evidence from cross adaptation
-
Schiffman, S.S., Cahn, H. and Lindley, M.G. (1981) Multiple receptor sites mediate sweetness: evidence from cross adaptation. Pharmacol. Biochem. Behav., 15, 377-388.
-
(1981)
Pharmacol. Biochem. Behav.
, vol.15
, pp. 377-388
-
-
Schiffman, S.S.1
Cahn, H.2
Lindley, M.G.3
-
81
-
-
0020962398
-
Recognition of cholinergic agonists by the muscarinic receptor. 1. Acetylcholine and other agonists with the NCCOCC backbone
-
Schulman, J.M., Sabio, M.L. and Disch, R.L. (1983) Recognition of cholinergic agonists by the muscarinic receptor. 1. Acetylcholine and other agonists with the NCCOCC backbone. J. Med. Chem., 26, 817-823.
-
(1983)
J. Med. Chem.
, vol.26
, pp. 817-823
-
-
Schulman, J.M.1
Sabio, M.L.2
Disch, R.L.3
-
82
-
-
0014192965
-
Molecular theory of sweet taste
-
Shallenberger, R.S. and Acree, T.E. (1967) Molecular theory of sweet taste. Nature, 216, 480-482.
-
(1967)
Nature
, vol.216
, pp. 480-482
-
-
Shallenberger, R.S.1
Acree, T.E.2
-
83
-
-
0014667672
-
Sweet taste of D and L-sugars and amino-acids and the steric nature of their chemo-receptor site
-
Shallenberger, R.S., Acree, T.E. and Lee, C.Y. (1969) Sweet taste of D and L-sugars and amino-acids and the steric nature of their chemo-receptor site. Nature, 221, 555-556.
-
(1969)
Nature
, vol.221
, pp. 555-556
-
-
Shallenberger, R.S.1
Acree, T.E.2
Lee, C.Y.3
-
84
-
-
0026416668
-
Reconciling the magnitude of the microscopic and macroscopic hydrophobic effects
-
Sharp, K.A., Nicholls, A., Fine, R.F. and Honig, B. (1991) Reconciling the magnitude of the microscopic and macroscopic hydrophobic effects. Science, 252, 106-109.
-
(1991)
Science
, vol.252
, pp. 106-109
-
-
Sharp, K.A.1
Nicholls, A.2
Fine, R.F.3
Honig, B.4
-
85
-
-
0028905124
-
Binding of phosphorus-containing inhibitors to thermolysin studied by the Poisson-Boltzmann method
-
Shen, J. and Wendoloski, J. (1995) Binding of phosphorus-containing inhibitors to thermolysin studied by the Poisson-Boltzmann method. Protein Sci.,4, 373-381.
-
(1995)
Protein Sci.
, vol.4
, pp. 373-381
-
-
Shen, J.1
Wendoloski, J.2
-
86
-
-
0023009886
-
Photoaffinity labeling of thaumatin-binding protein in monkey circumvallate papillae
-
Shimazaki, K., Sato, M. and Nakao, M. (1986) Photoaffinity labeling of thaumatin-binding protein in monkey circumvallate papillae. Biochim. Biophys. Acta, 884, 291-298.
-
(1986)
Biochim. Biophys. Acta
, vol.884
, pp. 291-298
-
-
Shimazaki, K.1
Sato, M.2
Nakao, M.3
-
87
-
-
0001567217
-
Inherited taste deficiency
-
Snyder, L.H. (1931) Inherited taste deficiency. Science, 74, 151-152.
-
(1931)
Science
, vol.74
, pp. 151-152
-
-
Snyder, L.H.1
-
88
-
-
37049091573
-
1H nuclear magnetic resonance spectroscopic, potentiometric, and conductimetric methods
-
1H nuclear magnetic resonance spectroscopic, potentiometric, and conductimetric methods. J. Chem. Soc. Perkin Trans. II, 580-584.
-
(1977)
J. Chem. Soc. Perkin Trans. II
, pp. 580-584
-
-
Spillane, W.J.1
Thomson, J.B.2
-
90
-
-
0024361826
-
Sweet tastants stimulate adenylate cyclase coupled to GTP-binding protein in rat tongue membranes
-
Striem, B.J., Pace, U., Zehavi, U., Naim, M. and Lancet, D. (1989) Sweet tastants stimulate adenylate cyclase coupled to GTP-binding protein in rat tongue membranes. Biochem. J., 260, 121-126.
-
(1989)
Biochem. J.
, vol.260
, pp. 121-126
-
-
Striem, B.J.1
Pace, U.2
Zehavi, U.3
Naim, M.4
Lancet, D.5
-
91
-
-
0000162332
-
Benzene forms hydrogen bonds with water
-
Suzuki, S., Green, P.G., Bumgarner, R.E., Dasgupta, S., Goddard, W.A., III and Blake, G.A. (1992) Benzene forms hydrogen bonds with water. Science, 257, 942-945.
-
(1992)
Science
, vol.257
, pp. 942-945
-
-
Suzuki, S.1
Green, P.G.2
Bumgarner, R.E.3
Dasgupta, S.4
Goddard III, W.A.5
Blake, G.A.6
-
92
-
-
0028102849
-
Effect of conformational flexibility and solvation on receptor-ligand binding free energies
-
Vajda, S., Weng, Z., Rosenfeld, R. and DeLisi, C. (1994) Effect of conformational flexibility and solvation on receptor-ligand binding free energies. Biochemistry, 33, 13977-13988.
-
(1994)
Biochemistry
, vol.33
, pp. 13977-13988
-
-
Vajda, S.1
Weng, Z.2
Rosenfeld, R.3
DeLisi, C.4
-
93
-
-
0021954737
-
Structure-activity relationships in sweeteners. I. Nitroanilines, sulphamates, oximes, isocoumarins and dipeptides
-
van der Heijden, A., van der Wel, H. and Peer, H.G. (1985a) Structure-activity relationships in sweeteners. I. Nitroanilines, sulphamates, oximes, isocoumarins and dipeptides. Chem. Senses, 10, 57-72.
-
(1985)
Chem. Senses
, vol.10
, pp. 57-72
-
-
Van Der Heijden, A.1
Van Der Wel, H.2
Peer, H.G.3
-
94
-
-
0021912909
-
Structure-activity relationships in sweeteners. II. Saccharins, acesulfames, chlorosugars, tryptophans and ureas
-
van der Heijden, A., van der Wel, H. and Peer, H.G. (1985b) Structure-activity relationships in sweeteners. II. Saccharins, acesulfames, chlorosugars, tryptophans and ureas. Chem. Senses, 10, 73-88.
-
(1985)
Chem. Senses
, vol.10
, pp. 73-88
-
-
Van Der Heijden, A.1
Van Der Wel, H.2
Peer, H.G.3
-
95
-
-
0026554077
-
Crystal-structure-based design and synthesis of benz[cd]indole-containing inhibitors of thymidylate synthase
-
Varney, M.D., Marzoni, G.P., Palmer, C.L., Deal, J.G., Webber, S., Welsh, K.M., Bacquet, R.J., Bartlett, C.A., Morse, C.A., Booth, C.L.J., Herrmann, S.M., Howland, E.F., Ward, R.W. and White, J. (1992) Crystal-structure-based design and synthesis of benz[cd]indole-containing inhibitors of thymidylate synthase. J. Med. Chem., 35, 663-676.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 663-676
-
-
Varney, M.D.1
Marzoni, G.P.2
Palmer, C.L.3
Deal, J.G.4
Webber, S.5
Welsh, K.M.6
Bacquet, R.J.7
Bartlett, C.A.8
Morse, C.A.9
Booth, C.L.J.10
Herrmann, S.M.11
Howland, E.F.12
Ward, R.W.13
White, J.14
-
96
-
-
0028773887
-
Structure-based drug design: Progress, results and challenges
-
Verlinde, C.L.M.J. and Hol, W.G.J. (1994) Structure-based drug design: progress, results and challenges. Structure, 2, 577-587.
-
(1994)
Structure
, vol.2
, pp. 577-587
-
-
Verlinde, C.L.M.J.1
Hol, W.G.J.2
-
97
-
-
0027287506
-
Rational design of potent sialidase-based inhibitors of influenza virus replication
-
von Itzstein, M., Wu, W.-Y., Kok, G.B., Pegg, M.S., Dyason, J.C., Jin, B., Van Phan, T., Smythe, M.L., White, H.F., Oliver, S.W., Colman, P.M., Varghese, J.N., Ryan, D.M., Woods, J.M., Bethell, R.C., Hotham, V.J., Cameron, J.M. and Penn, C.R. (1993) Rational design of potent sialidase-based inhibitors of influenza virus replication. Nature, 363, 418-423.
-
(1993)
Nature
, vol.363
, pp. 418-423
-
-
Von Itzstein, M.1
Wu, W.-Y.2
Kok, G.B.3
Pegg, M.S.4
Dyason, J.C.5
Jin, B.6
Van Phan, T.7
Smythe, M.L.8
White, H.F.9
Oliver, S.W.10
Colman, P.M.11
Varghese, J.N.12
Ryan, D.M.13
Woods, J.M.14
Bethell, R.C.15
Hotham, V.J.16
Cameron, J.M.17
Penn, C.R.18
-
98
-
-
0027439587
-
Further development of hydrogen bond functions for use in determining energetically favorable binding sites on molecules of known structure. 1. Ligand probe groups with the ability to form two hydrogen bonds
-
Wade, R.C., Clark, K.J. and Goodford, P.J. (1993) Further development of hydrogen bond functions for use in determining energetically favorable binding sites on molecules of known structure. 1. Ligand probe groups with the ability to form two hydrogen bonds. J. Med. Chem., 36, 140-147.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 140-147
-
-
Wade, R.C.1
Clark, K.J.2
Goodford, P.J.3
-
99
-
-
0027510004
-
Further development of hydrogen bond functions for use in determining energetically favorable binding sites on molecules of known structure. 2. Ligand probe groups with the ability to form more than two hydrogen bonds
-
Wade, R.C. and Goodford, P.J. (1993) Further development of hydrogen bond functions for use in determining energetically favorable binding sites on molecules of known structure. 2. Ligand probe groups with the ability to form more than two hydrogen bonds. J. Med. Chem., 36, 148-156.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 148-156
-
-
Wade, R.C.1
Goodford, P.J.2
-
102
-
-
0025886180
-
Toward the semiquantitative estimation of binding constants. Guides for peptide-peptide binding in aqueous solution
-
Williams, D.H., Cox, J.P.L., Doig, A.J., Gardner, M., Gerhard, U., Kaye, P.T., Lal, A.R., Nicholls, I.A., Salter, C.J. and Mitchell, R.C. (1991). Toward the semiquantitative estimation of binding constants. Guides for peptide-peptide binding in aqueous solution. J. Am. Chem. Soc., 113, 7020-7030.
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 7020-7030
-
-
Williams, D.H.1
Cox, J.P.L.2
Doig, A.J.3
Gardner, M.4
Gerhard, U.5
Kaye, P.T.6
Lal, A.R.7
Nicholls, I.A.8
Salter, C.J.9
Mitchell, R.C.10
-
103
-
-
0027475726
-
Toward an estimation of binding constants in aqueous solution: Studies of associations of vancomycin group antibiotics
-
Williams, D.H., Searle, M.S., Mackay, J.P., Gerhard, U., Maplestone, R.A. (1993) Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics. Proc. Natl. Acad. Sci. USA, 90, 1172-1178.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1172-1178
-
-
Williams, D.H.1
Searle, M.S.2
Mackay, J.P.3
Gerhard, U.4
Maplestone, R.A.5
|