A novel family of putative pheromone receptors in mammals with a topographically organized and sexually dimorphic distribution

Cell

Volumn 90, Issue 4, 1997, Pages 763-773

  Herrada, Gilles ^a   Dulac, Catherine ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; GLUTAMIC ACID; MEMBRANE RECEPTOR; PHEROMONE; PHEROMONE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DNA DETERMINATION; MEMBRANE BINDING; NEUROSECRETORY CELL; NONHUMAN; OLFACTORY EPITHELIUM; OLFACTORY SYSTEM; PRIORITY JOURNAL; RECEPTOR BINDING; SEQUENCE HOMOLOGY; SEX DIFFERENCE; VOMERONASAL ORGAN;

ANIMALIA; MAMMALIA;

EID: 0030788436     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80536-X     Document Type: Article

References (47)

1. i2 and adenylyl cyclase II as major components of a pheromone signaling cascade. J. Neurosci. 16, 909-918.
2. Berliner, D.L., Montibloch, L., Jenningswhite, C., and Diazsanchez, V. (1996). The functionality of the human vomeronasal organ (VNO)-evidence for steroid receptors. J. Steroid Biochem. Mol. Biol. 58, 259-265.
3. 2+-sensing receptor from bovine parathyroid. Nature 366, 575-580.
4. Buck, L., and Axel, R. (1991). A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 65, 175-187.
5. Dulac, C., and Axel, R. (1995). A novel family of genes encoding putative pheromone receptors in mammals. Cell 83, 195-206.
6. Gomeza, J., Joly, C., Kuhn, R., Knöpfel, T., Bockaert, J., and Pin, I.P. (1996). The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins. J. Biol. Chem. 271, 2199-2205.
7. Halpern, M. (1987). The organization and function of the vomeronasal system. Annu. Rev. Neurosci. 10, 325-362.
8. Halpern, M., Shapiro, L.S., and Jia, C. (1995). Differential localization of G proteins in the opossum vomeronasal system. Brain Res. 677, 157-161.
9. Henzel, W.J., Rodriguez, H., Singer, A.G., Stults, J.T., Macrides, F., Agosta, W.C., and Niall, H. (1988). The primary structure of aphrodisin. J. Biol. Chem. 263(32), 16682-16687.
10. Houamed, K.M., Kuijper, J.L., Gilbert, T.L., Haldeman, B.A., O'Hara, P.J., Mulvihill, E.R., Almers, W., and Hagen, F.S. (1991). Cloning, expression, and gene structure of a G-protein-coupled glutamate receptor from rat brain. Science 252, 1318-1321.
11. Humphrey, T. (1940). The development of the olfactory and the accessory formations in human embryos and fetuses. J. Comp. Neural. 73, 431-468.
12. Ichikawa, M., Takami, S., Osada, T., and Graziadei, P.C. (1994). Differential development of binding sites of two lectins in the vomeronasal axons of the rat accessory olfactory bulb. Dev. Brain Res. 78, 1-9.
13. Imamura, K., Mori, K., Fujita, S.C., and Obata, K. (1985). Immunocy-tochemical identification of subgroups of vomeronasal nerve fibers and their segregated terminations in the accessory olfactory bulb. Brain Res. 328, 362-366.
14. Jacobson, L. (1811). Description anatomique d'un organe observe dans les Mammiferes. Ann. Mus. Hist. Natn. Paris 18, 412-424.
15. Jiang, X.C., Inouchi, J., Wang, D., and Halpern, M. (1990). Purification and characterization of a chemoattractant from electric shock-induced earthworm secretion, its receptor binding, and signal transduction through the vomeronasal system of garter snakes. J. Biol. Chem. 265, 8736-8744.
16. B receptors uncovers similarity to metabotropic glutamate receptors. Nature 386, 239-246.
17. Kikuyama, S., Toyoda, F., Ohmiya, Y., Matsuda, K., Tanaka, S. and Hayashi, H. (1995). Sodefrin: a female-attracting peptide pheromone in newt cloacal glands. Science 267,1643-1645.
18. Kobilka, B.K., Kobilka, T.S., Daniel, K., Regan, J.W., Caron, M.G., and Lefkowitz, R.J. (1988). Chimeric a2-b2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity. Science 240, 1310-1316.
19. Liman, E.R. (1996). Pheromone transduction in the vomeronasal organ. Neurobiology 6, 487-493.
20. Masu, M., Tanbe, Y., Tsuchida, K., Shigemoto, R., and Nakanishi, S. (1991). Sequence and expression of a metabotropic glutamate receptor. Nature 349, 760-765.
21. Matsunami, H., and Buck, L.B. (1997). A multigene family encoding a diverse array of putative pheromone receptors in mammals. Cell, this issue, 90, 775-784.
22. Melrose, D.R., Reed, H.C., and Patterson, R.L. (1971). Androgen steroids associated with boar odour as an aid to the detection of oestrus in pig artificial insemination. Brit. Vet. J. 127, 497-502.
23. Menzies, R.A., Heth,G., Ikan, R., Weinstein, V., and Nevo, E. (1992). Sexual pheromones in lipids and other fractions from urine of the male mole rat, Spalax ehrenbergi, Physiol. Behav. 52, 741-747.
24. Mombaerts, P., Wang, F., Dulac, C., Chao, S., Nemes, A., Mendelsohn, M., Edmondson, J., and Axel, R. (1996). Visualizing an olfactory sensory map. Cell 87, 675-686.
25. Mori, K. (1987). Monoclonal antibodies (2C5 and 4C9) against lactoseries carbohydrates identify subsets of olfactory and vomeronasal receptor cells and their axons in the rabbit. Brain Res. 408, 215-221.
26. Murphy, M.R., and Schneider, G.E. (1970). Olfactory bulb removal eliminates mating behaviour in the male golden hamster. Science 167, 302-304.
27. Ngai, J., Chess, A., Dowling, M.M., Necles, N., Macagno, E.R., and Axel, R. (1993). Coding of olfactory information: topography of odorant receptor expression in the catfish olfactory epithelium. Cell 72, 667-680.
28. 2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism.Cell 75, 1297-1303.
29. Rasmussen, L.E.I., Lee, T.D., Roelof, W.L., Zang, A.J., and Daves, G.D. (1996). Insect pheromones in elephants. Nature 379, 684.
30. Ressler, K.J., Sullivan, S.L., and Buck, L.B. (1993). A zonal organization of odorant receptor gene expression in the olfactory epithelium. Cell 73, 597-609.
31. Ressler, K.J., Sullivan, S., and Buck, L.B. (1994). Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell 79, 1245-1255.
32. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, 2nd Ed. (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press).
33. Schaeren-Wiemers, N., and Gerfin-Moser, A. (1993). A single protocol to detect transcripts of various types and expression levels in neural tissue and cultures cells: in situ hybridization using digoxigenin-labeled cRNA probes. Histochemistry 100, 431-440.
34. Scheller, H.R., Jackson, F.J., McAllister, B., Schwartz, J.H., Kandel, R.E., and Axel, R. (1982). A family of genes that codes for EHL, a neuropeptide eliciting a stereotyped pattern of behavior in Aplysia. Cell 28, 707-719.
35. Sengupta, P., Chou, J.H., and Bargmann, C.I. (1996). ODR-10 encodes a seven transmembrane domain olfactory receptor required for responses to the odorant diacetyl. Cell 84, 899-909.
36. o, in the olfactory epithelium and the main olfactory bulb of rat. Acta Anat. 144, 167-171.
37. Singer, A.G., Macrides, F., Clancy, A.N., and Agosta, W.C. (1986). Purification and analysis of a proteinaceous aphrodisiac pheromone from hamster vaginal discharge. J. Biol. Chem. 261, 3323-3326.
38. Sorensen, P.W., Hara, T.J., Stacey, N.E., and Goetz, F.W. (1988). F prostaglandins function as potent olfactory stimulants that com prise the postovulatory female sex pheromone in goldfish. Biol. Reprod. 39, 1039-1050.
39. Strader, C.D., Sigal, I.S., Register, R.B.,Candelore, M.R., Rands, E., and Dixon, R.A.F. (1987). Identification of residues required for ligand binding to the b-adrenergic receptor. Proc. Natl. Acad. Sci. USA 84, 4348-4388.
40. Strader, C.D., Fong, T.M., Tota, M.R., and Underwood, D. (1994). Structure and function of G protein-coupled receptors. Annu. Rev. Biochem. 63, 101-132.
41. Sullivan, S.L., Bohm, S., Ressler, K.J., Horowitz, L.F., and Buck, L.B. (1995). Target independent pattern specification in the olfactory epithelium. Neuron 15, 779-789.
42. Troemel, E.R., Chou, J.H., Dwyer, N.D., Colbert, H.A., and Bargmann, C.I. (1995). Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans. Cell 83, 207-218.
43. Vassar, R., Ngai, J., and Axel, R. (1993). Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell 74, 309-318.
44. Vassar, R., Chao, S.K., Sitcheran, R., Nunez, J.M., Vosshall, L.B., and Axel, R. (1994). Topographic organization of sensory projections to the olfactory bulb. Cell 79, 981-991.
45. von Heijne, G. (1986). A new method for predicting signal sequence cleavage sites. Nucleic Acids Res. 14, 4683-4690.
46. Wilson, E. (1963). Pheromones. Sci. Am. 5, 2-11.
47. Wysocki, C.J. (1989). Vomeronasal chemoreception: its role in reproductive fitness and physiology. In Neural Control of Reproductive Function (New York: Alan R. Liss, Inc.), pp. 545-566.