Applications of microarray technology in breast cancer research

Breast Cancer Research

Volumn 3, Issue 3, 2001, Pages 158-175

  Cooper, C S ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Drug discovery; Genetic gains and losses; Microarray design; Microarrays; Mutation detection; Tumour classification

Indexed keywords

17 ALLYLAMINO 17 DEMETHOXYGELANAMYCIN; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE; CHAPERONE; COMPOUND 52; CYCLOSPORIN A; DNA; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE INHIBITOR; DYCLONINE; FLUAROPIRIDOL; FLUOROURACIL; GYRASE INHIBITOR; MITOMYCIN; MITOXANTRONE; OXANTHRAZOLE; PORFIROMYCIN; PURVALANOL; TACROLIMUS; TUBULIN; TUBULIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; BREAST CANCER; CANCER RESEARCH; CARCINOGENESIS; CHROMOSOME; CONTROLLED STUDY; DNA MICROARRAY; DNA SEQUENCE; DRUG DEVELOPMENT; DRUG RESEARCH; HEALTH; HUMAN; HUMAN CELL; MEDICAL GENETICS; MEDICAL INFORMATION; MEDICAL TECHNOLOGY; MONITORING; MUTATION; NONHUMAN; REVIEW; TUMOR CLASSIFICATION;

BREAST NEOPLASMS; CHROMOSOME MAPPING; DNA, NEOPLASM; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENOME, HUMAN; HUMANS; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TRANSCRIPTION, GENETIC;

EID: 0035028333     PISSN: 14655411     EISSN: None     Source Type: Journal    
DOI: 10.1186/bcr291     Document Type: Review

References (99)

1. Gene expression informatics - Its all in your mine
2. DNA chips: State-of-the-art
3. Accessing genetic information with high-density DNA arrays
4. Expression monitoring by hybridisation to high-density oligonucleotide arrays
5. High density synthetic oligonucleotide arrays
6. Parallel human genome analysis: Microarray-based expression monitoring of 1000 genes
7. Use of a cDNA microarray to analyse gene expression patterns in human cancer
8. Microarray fabrication with covalent attachment of DNA using bubble jet technology
9. Rapid, high fidelity analysis of simple sequence repeats on an electronically active DNA microchip
10. Processing of cDNA and genomic kilo-base-size clones for massive screening, mapping and sequencing by hybridisation
11. Gene-representing cDNA clusters defined by hybridisation of 57,419 clones from infant brain libraries with short oligonucleotide probes
12. DNA sequence recognition by hybridisations to short oligomers: Experimental verification of the method on the E. coli genome
13. DNA analysis and diagnostics on oligonucleotide microchips
14. Molecular interactions on microarrays
15. Making and reading microarrays
16. Light-directed, spatially addressable parallel chemical synthesis
17. Light-generated oligonucleotide arrays for rapid DNA sequence analysis
18. Light-directed synthesis of high density oligonucleotide arrays using semiconductor photoresists
19. Enhanced high density oligonucleotide array-based sequence analysis using modified nucleoside triphosphates
20. The human CAS (cellular apoptosis susceptibility) gene mapping on chromosome 20q13 is amplified in BT474 breast cancer cells and part of aberrant chromosomes in breast and colon cancer cell lines
21. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer
22. A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines
23. Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
24. Prognostic importance of c-erbB-2 expression in breast cancer
25. Amplification of chromosomal region 20q13 in invasive breast cancer: Prognostic implications
26. Genome screening by comparative genomic hybridisation
27. High resolution analysis of DNA copy number variation using comparative genomic hybridisation to microarrays
28. Genome-wide analysis of DNA copy-number changes using cDNA microarrays
29. Detection of gene amplification by genomic hybridisation to cDNA microarrays
30. Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
31. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
32. Systematic variation in gene expression patterns in human cancer cell lines
33. Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays
34. In vivo gene expression profile analysis of human breast cancer progression
35. Molecular portraits of human breast tumours
36. DNA microarrays in drug discovery and development
37. A gene expression database for the molecular pharmacology of cancer
38. Drug target validation and identification of secondary drug target effects using DNA microarrays
39. Functional discovery via a compemdium of expression profiles
40. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors
41. Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone
42. Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-colour fluorescence analysis
43. Resequencing and mutational analysis using oligonucleotide microarrays
44. Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array
45. Elevated frequency and functional activity of a specific germ-line p53 intron mutation in familial breast cancer
46. Comparison of TP53 mutations identified by oligonucleotide microarray and conventional DNA sequence analysis
47. Comparative evaluation of three human immunodeficiency virus genotyping systems: The HIV-Genotype R method, the HIV PRT GeneChip assay and the HIV RT line probe assay
48. From gels to chips: 'Minisequencing' primer extension for analysis of point mutations and single nucleotide polymorphisms
49. Universal DNA array detection of small insertsions and deletions in BRCA1 and BRCA2
50. Universal DNA microarray method for multiplex detection of low abundance point mutations
51. Universal DNA microarray method for multiplex detection of low abundance point mutations
52. Mutation detection in K-ras, BRCA1, BRCA2, and p53 using PCR/LDR and a universal DNA microarray
53. cDNA miroarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene
54. Induction of GADD45 and JNK/SAPK-Dependent apoptosis following inducible expression of BRCA1
55. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth cell cycle signaling and adhesion
56. Analysis of p53-regulated gene expression patterns using oligonucleotide arrays
57. Fluorescent cDNA microarray hybridisation reveals complexity and heterogeneity of cellular genotoxic stress responses
58. Gene microarray identification of redox and mitochondrial elements that control resistance or sensitivity to apoptosis
59. Identification of eukaryotic mRNAs that are translated at reduced cap binding complex elF4F concentrations using a cDNA microarray
60. Large-scale identification of secreted and membrane-associated gene products using DNA microarrays
61. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
62. Identification of B94 (TNFAIP2) as a potential retinoic acid target gene in acute promyelocytic leukemia
63. Stimulation of B and T cells activates expression of transcription and differentiation factors
64. Activation changes the spectrum but not the diversity of genes expressed by T cells
65. Transcript imaging of the development of human T helper cells using oligonucleotide arrays
66. The transcriptional program in the response of human fibroblasts to serum
67. Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa tissue factor-induced transduction
68. Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays
69. Stimulation of peripheral cannabinoid receptor CB2 induces MCP-1 and IL-8 gene expression in human promyelocytic cell line HL60
70. Prostate-localised and androgen-regulated expression of the membrane-bound serine protease TMPRSS2
71. Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2 and 3 genes in colon tumor cells
72. Statistical analysis of array expression data as applied to the problem of tamoxifen resistance
73. Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomarvirus type 31
74. Hormone therapy failure in human prostate cancer: Analysis by complementary DNA and tissue microarrays
75. Microarray-based expression profiling in prostate tumors
76. Development of a prostate cDNA microarray and statistical gene expression analysis package
77. Identification of genes overexpressed in head and neck squamous cell carcinoma using a combination of complementary DNA subtraction and microarray analysis
78. Identification of differentially expressed genes in human prostate cancer using subtraction and microarray
79. Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes
80. Identification of genes differentially over-expressed in lung squamous cell carcinoma using combination of cDNA subtraction and microarray analysis
81. Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays
82. Molecular features of a human rhabdomyosracoma cell line with spontaneous metastatic progression
83. Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray
84. High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma
85. Vascular channel formation by human melanoma cells in vivo and in vitro: Vasculogenic mimicry
86. Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridisation
87. Novel strategy yields candidate Gsh-1 homeobox gene targets using hypothalamus progenitor cell lines
88. The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin
89. The genetic program of hematopoietic stem cells
90. Identification of Cd36 (fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
91. Antisense RNA amplfication: A linear amplification method for analysing the mRNA population from single living cells
92. Non-stoichiometric reduced complexity probes for cDNA arrays
93. High-fidelity mRNA amplification for gene profiling
94. Application of complementary DNA microarray technology to carcinogen identification, toxicology, and drug safety evaluation
95. Microarrays and toxicology: The advent of toxicogenomics
96. Tissue microarrays for high-throughput molecular profiling of tumor specimens