Universal DNA array detection of small insertions and deletions in BRCA1 and BRCA2

Nature Biotechnology

Volumn 18, Issue 5, 2000, Pages 561-564

  Favis, Reyna ^a   Day, Joseph P ^a   Gerry, Norman P ^a   Phelan, Catherine ^b   Narod, Steven ^b   Barany, Francis ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DNA; GENE PRODUCT;

ARTICLE; DNA HYBRIDIZATION; DNA SEQUENCE; FLUORESCENCE; FOUNDER EFFECT; FRAMESHIFT MUTATION; GENE DELETION; GENE INSERTION; HUMAN; JEW; LIGASE CHAIN REACTION; OLIGONUCLEOTIDE PROBE; ONCOGENE; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL;

BRCA1 PROTEIN; BRCA2 PROTEIN; DNA PRIMERS; FOUNDER EFFECT; FRAMESHIFT MUTATION; HUMANS; JEWS; MUTAGENESIS, INSERTIONAL; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEQUENCE DELETION; TRANSCRIPTION FACTORS;

EID: 0034121447     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/75452     Document Type: Article

References (16)

1. Kozal, M.J. et al. Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays. Nat. Med. 2, 753-759 (1996).
2. Belgrader, P., Marino, M., Lubin, M. & Barany, F. A multiplex PCR-ligase detection reaction assay tor human identity testing. Genome Sci. Technol. 1, 77-87 (1996).
3. Khanna, M. et al. Multiplex PCR/LDR for detection of K-ras mutations in primary colon tumors. Oncogens 18, 27-38 (1999).
4. Gerry, N. et al. Universal DNA microarray method (or multiplex detection of low abundance point mutations. J. Mol. Biol. 292, 251-262 (1999).
5. Rahman, N. & Stratton, M. The genetics of breast cancer susceptibility. Annu. Rev. Genet. 32, 95-121 (1998).
6. Hacia, J., Brody, L., Chee, M., Fodor, S. & Collins, F. Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-colour fluorescence analysis. Nat. Genet. 14, 441-447 (1996).
7. Ahrendt, S. et al. Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array. Proc. Natl. Acad. Sci. USA. 96, 7382-7387 (1999).
8. Hacia, J. Resequencing and mutational analysis using oligonucleotide microarrays. Nat. Genet. (Suppl.) 21, 42-47 (1999).
9. Syvanen, A.C. & Landegren, U. Detection of point mutations by solid-phase methods. Hum. Mutat. 3, 172-179 (1994).
10. Tong, J., Cao, W. & Barany, F. Biochemical properties of a high fidelity DNA ligase from Thermus species AK16D. Nucleic Acids Res. 27, 788-794 (1999).
11. Luo, J., Bergstrom, D.E. & Barany, F. Improving the fidelity of Thermus thermophilus DNA ligase. Nucleic Acids Res. 24, 3071-3078 (1996).
12. Zirvi, M. et al. Ligase-based detection of mononucleotide repeat sequences. Nucleic Acids Res. 27, e40 (1999).
13. Zirvi, M., Bergstrom, D.E., Saurage, A.S., Hammer, R.P. & Barany, F. Improved fidelity of thermostable ligases for detection of microsatellite repeat sequences using nucleoside analogs. Nucleic Acids Res. 27, e41 (1999).
14. Chakravarti, A. Population genetics - making sense out of sequence. Nat. Genet. 21, 56-60 (1999).
15. Luo, J. & Barany, F. Identification of essential residues in Thermus thermophilus DNA ligase. Nucleic Acids Res. 24, 3079-3085 (1996).
16. Barany, F. & Gelfand, D. Cloning, overexpression, and nucleotide sequence of a thermostable DNA ligase gene. Gene 109, 1-11 (1991).