Location of a constriction in the lumen of a transmembrane pore by targeted covalent attachment of polymer molecules

Journal of General Physiology

Volumn 117, Issue 3, 2001, Pages 239-251

  Movileanu, Liviu ^a   Cheley, Stephen ^a   Howorka, Stefan ^a   Braha, Orit ^a   Bayley, Hagan ^a,b  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

hemolysin; Cysteine scanning mutagenesis; Poly(ethylene glycol); Pore; Sulfhydryl reagent

Indexed keywords

CYSTEINE; HEMOLYSIN; ION; ION CHANNEL; MACROGOL DERIVATIVE; MEMBRANE PROTEIN; THIOL DERIVATIVE;

ANALYTIC METHOD; CONDUCTANCE; CONFERENCE PAPER; CONTROLLED STUDY; COVALENT BOND; CRYSTAL STRUCTURE; ELECTROPHYSIOLOGY; MOLECULAR WEIGHT; MUTAGENESIS; PROTEIN STRUCTURE; QUANTITATIVE ASSAY; STRUCTURE ANALYSIS; TRANSPORT KINETICS;

ANIMALS; BACTERIAL TOXINS; BINDING SITES; CELL MEMBRANE; CYSTEINE; HEMOLYSIN PROTEINS; ION CHANNELS; MUTAGENESIS, SITE-DIRECTED; POLYMERASE CHAIN REACTION; POLYMERS; PROTEIN CONFORMATION; RABBITS;

EID: 0035025417     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.117.3.239     Document Type: Conference Paper

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