Role of interleukin-12 in the induction of mucosal inflammation and abrogation of regulatory T cell function in chronic experimental colitis

European Journal of Immunology

Volumn 31, Issue 5, 2001, Pages 1550-1560

  Liu, Zhanju ^a   Geboes, Karel ^a   Heremans, Hubertine ^b   Overbergh, Lutgart ^a   Mathieu, Chantai ^a   Rutgeerts, Paul ^a   Ceuppens, Jan L ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

IL 12; Inflammatory bowel disease; Regulatory T cell; Scid mouse; Th1; Th2

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CYTOKINE; CYTOKINE ANTIBODY; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12; INTERLEUKIN 12 ANTIBODY; LYMPHOCYTE ANTIBODY; MESSENGER RNA; PROTEIN P40; UNCLASSIFIED DRUG;

ANALYSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL TRANSFER; CELLULAR IMMUNITY; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FEMALE; GENE INDUCTION; IN VITRO STUDY; LEUKOCYTE; LYMPHOCYTE FUNCTION; MACROPHAGE; MOUSE; MUCOSA INFLAMMATION; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCID MOUSE; SPLEEN CELL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH1 CELL; TIME; WASTING SYNDROME;

ANIMALS; ANTIBODIES; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; CHRONIC DISEASE; COLITIS; COLON; DISEASE MODELS, ANIMAL; FEMALE; IMMUNITY, MUCOSAL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON TYPE II; INTERLEUKIN-12; KINETICS; MICE; MICE, INBRED BALB C; MICE, SCID; RECURRENCE; RNA, MESSENGER; SPLEEN;

EID: 0034998259     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200105)31:5<1550::AID-IMMU1550>3.0.CO;2-3     Document Type: Article

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