Quantitative analysis of transgene protein, mRNA, and vector DNA following injection of an adenoviral vector harboring glial cell line-derived neurotrophic factor into the primate caudate nucleus

Molecular Therapy

Volumn 3, Issue 2, 2001, Pages 256-261

  Kozlowski, Dorothy A ^a   Bremer, Eric ^a   Redmond Jr , D Eugene ^b   George, David ^a   Larson, Beth ^a   Bohn, Martha C ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dopamine neurons; Gene therapy; Neurotrophic factor; Nigrostriatal system; Parkinson's disease; Real time RT PCR

Indexed keywords

BETA ACTIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; VIRUS PROTEIN; VIRUS VECTOR;

ADENOVIRUS; ANIMAL TISSUE; ARTICLE; CAUDATE NUCLEUS; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEGENERATIVE DISEASE; DNA VECTOR; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE DELETION; GENE EXPRESSION; GENE THERAPY; HISTOLOGY; HUMAN; INJECTION; MALE; MONKEY; NEUROPROTECTION; NONHUMAN; POLYMERASE CHAIN REACTION; PREDICTION; PRIMATE; QUANTITATIVE ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENE;

ADENOVIRIDAE; ANIMALIA; CERCOPITHECUS AETHIOPS; PRIMATES;

EID: 0034981133     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2000.0256     Document Type: Article

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