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Volumn 12, Issue 2-3, 2001, Pages 189-205

X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOKINE; ENZYME ACTIVATOR; GROWTH FACTOR; GROWTH PROMOTOR; HEPATITIS B VIRUS X PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN P53; PROTEIN X; STAT PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANS ACTIVATORS; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; VIRUS PROTEIN;

EID: 0034954277     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6101(00)00034-4     Document Type: Review
Times cited : (146)

References (187)
  • 6
    • 0028306247 scopus 로고
    • Molecular events in the pathogenesis of hepadnavirus-associated hepatocellular carcinoma
    • (1994) Annu Rev Med , vol.45 , pp. 297-323
    • Robinson, W.S.1
  • 8
    • 0024391379 scopus 로고
    • Transcriptional activation of homologous and heterologous genes by the hepatitis B virus X gene product in cells permissive for viral replication
    • (1989) J Virol , vol.63 , Issue.9 , pp. 4019-4026
    • Colgrove, R.1    Simon, G.2    Ganem, D.3
  • 12
    • 0029148749 scopus 로고
    • Hepatitis B virus transgenic mice: Insights into the virus and the disease
    • (1995) Hepatology , vol.22 , Issue.4 PART 1 , pp. 1316-1325
    • Chisari, F.V.1
  • 13
    • 0031051107 scopus 로고    scopus 로고
    • Virus-induced anti-asialoglycoprotein receptor autoimmunity in experimental hepadnaviral hepatitis
    • (1997) Hepatology , vol.25 , Issue.3 , pp. 689-696
    • Diao, J.1    Michalak, T.I.2
  • 14
    • 0031801298 scopus 로고    scopus 로고
    • Complement-mediated cytotoxicity and inhibition of ligand binding to hepatocytes by woodchuck hepatitis virus-induced autoantibodies to asialoglycoprotein receptor
    • (1998) Hepatology , vol.27 , Issue.6 , pp. 1623-1631
    • Diao, J.1    Churchill, N.D.2    Michalak, T.I.3
  • 15
  • 26
    • 0034167525 scopus 로고    scopus 로고
    • Rous-Whipple Award Lecture. Viruses, immunity, and cancer: Lessons from hepatitis B
    • (2000) Am J Pathol , vol.156 , Issue.4 , pp. 1117-1132
    • Chisari, F.V.1
  • 32
    • 0025758192 scopus 로고
    • Hepatocyte growth factor (hepatoprotein A) rapidly increases in plasma before DNA synthesis and liver regeneration stimulated by partial hepatectomy and carbon tetrachloride administration
    • (1991) Hepatology , vol.13 , Issue.4 , pp. 743-750
    • Lindroos, P.M.1    Zarnegar, R.2    Michalopoulos, G.K.3
  • 39
    • 0030042425 scopus 로고    scopus 로고
    • Liver regeneration in fulminant hepatitis as evaluated by serum transforming growth factor alpha levels
    • (1996) Hepatology , vol.23 , Issue.2 , pp. 253-257
    • Tomiya, T.1    Fujiwara, K.2
  • 51
    • 0034658541 scopus 로고    scopus 로고
    • Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2548-2556
    • Hirano, T.1    Ishihara, K.2    Hibi, M.3
  • 53
    • 0033551802 scopus 로고    scopus 로고
    • Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways
    • (1999) J Biol Chem , vol.274 , Issue.33 , pp. 23013-23019
    • Chen, R.H.1    Chang, M.C.2    Su, Y.H.3    Tsai, Y.T.4    Kuo, M.L.5
  • 55
    • 33746521801 scopus 로고
    • Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies
    • (1993) N Engl J Med , vol.328 , Issue.25 , pp. 1828-1835
    • Friedman, S.L.1
  • 60
    • 0026584374 scopus 로고
    • In vitro apoptosis in the human hepatoma cell line induced by transforming growth factor beta 1
    • (1992) Cancer Res , vol.52 , Issue.2 , pp. 385-388
    • Lin, J.K.1    Chou, C.K.2
  • 62
    • 0032924764 scopus 로고    scopus 로고
    • Inhibition of rat hepatocyte proliferation by transforming growth factor beta and glucagon is associated with inhibition of ERK2 and p70 S6 kinase
    • (1999) Hepatology , vol.29 , Issue.5 , pp. 1418-1424
    • Dixon, M.1    Agius, L.2    Yeaman, S.J.3    Day, C.P.4
  • 64
    • 0029776373 scopus 로고    scopus 로고
    • Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis
    • (1996) Carcinogenesis , vol.17 , Issue.8 , pp. 1623-1632
    • James, N.H.1    Roberts, R.A.2
  • 65
    • 0033950358 scopus 로고    scopus 로고
    • The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis
    • (2000) Hepatology , vol.31 , Issue.2 , pp. 420-427
    • Roberts, R.A.1    James, N.H.2    Cosulich, S.C.3
  • 66
    • 0032529220 scopus 로고    scopus 로고
    • TGF-beta inhibits IL-12-induced activation of Jak-STAT pathway in T lymphocytes
    • (1998) J Immunol , vol.161 , Issue.4 , pp. 1772-1777
    • Bright, J.J.1    Sriram, S.2
  • 67
    • 0027679506 scopus 로고
    • Induction of apoptosis by transforming growth factor-beta 1 in the rat hepatoma cell line McA-RH7777: A possible association with tissue transglutaminase expression
    • (1993) Hepatology , vol.18 , Issue.4 , pp. 945-953
    • Fukuda, K.1    Kojiro, M.2    Chiu, J.F.3
  • 68
    • 0029883399 scopus 로고    scopus 로고
    • The retinoblastoma gene product inhibits TGF-beta1 induced apoptosis in primary rat hepatocytes and human HuH-7 hepatoma cells
    • (1996) Oncogene , vol.12 , Issue.9 , pp. 1909-1919
    • Fan, G.1    Ma, X.2    Kren, B.T.3    Steer, C.J.4
  • 77
    • 0032697485 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways
    • (1999) J Biol Chem , vol.274 , Issue.43 , pp. 30603-30610
    • Hu, W.H.1    Johnson, H.2    Shu, H.B.3
  • 78
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • published erratum appears in Genes Dev Feb 1 1999;13(3):371
    • (1998) Genes Dev , vol.12 , Issue.11 , pp. 1551-1570
    • Cryns, V.1    Yuan, J.2
  • 93
    • 0031806909 scopus 로고    scopus 로고
    • Adenovirus E1B 19,000-molecular-weight protein activates c-jun N-terminal kinase and c-jun-mediated transcription
    • (1998) Mol Cell Biol , vol.18 , Issue.7 , pp. 4012-4022
    • See, R.H.1    Shi, Y.2
  • 97
  • 103
    • 0032934156 scopus 로고    scopus 로고
    • Functional roles of STAT family proteins: Lessons from knockout mice
    • (1999) Stem Cells , vol.17 , Issue.3 , pp. 138-146
    • Akira, S.1
  • 109
    • 0030902570 scopus 로고    scopus 로고
    • Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma
    • (1997) Am J Pathol , vol.150 , Issue.4 , pp. 1141-1157
    • Feitelson, M.A.1    Duan, L.X.2
  • 115
    • 0029586749 scopus 로고
    • Hepatitis B virus HBx gene and hepatocarcinogenesis
    • (1995) Intervirology , vol.38 , Issue.3-4 , pp. 134-142
    • Koike, K.1
  • 128
    • 0034708234 scopus 로고    scopus 로고
    • Induction of apoptosis by the transactivating domains of the hepatitis B virus X gene leads to suppression of oncogenic transformation of primary rat embryo fibroblasts
    • (2000) Oncogene , vol.19 , Issue.9 , pp. 1173-1180
    • Schuster, R.1    Gerlich, W.H.2    Schaefer, S.3
  • 132
    • 0025299483 scopus 로고
    • The X protein of the hepatitis B virus acts as a transcription factor when targeted to its responsive element
    • (1990) EMBO J , vol.9 , Issue.6 , pp. 1889-1895
    • Unger, T.1    Shaul, Y.2
  • 134
    • 0028878098 scopus 로고
    • Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation
    • (1995) EMBO J , vol.14 , Issue.1 , pp. 143-150
    • Cheong, J.H.1    Yi, M.2    Lin, Y.3    Murakami, S.4
  • 136
    • 0029896752 scopus 로고    scopus 로고
    • The hepatitis B virus transactivator protein, HBx, interacts with single-stranded DNA (ssdna). Biochemical characterizations of the HBx-ssDNA interactions
    • (1996) J Biol Chem , vol.271 , Issue.26 , pp. 15443-15450
    • Qadri, I.1    Ferrari, M.E.2    Siddiqui, A.3
  • 137
    • 0030056043 scopus 로고    scopus 로고
    • Px, the HBV-encoded coactivator, interacts with components of the transcription machinery and stimulates transcription in a TAF-independent manner
    • (1996) EMBO J , vol.15 , Issue.13 , pp. 3413-3420
    • Haviv, I.1    Vaizel, D.2    Shaul, Y.3
  • 138
    • 0025176474 scopus 로고
    • Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors
    • (1990) Nature , vol.344 , Issue.6261 , pp. 72-74
    • Seto, E.1    Mitchell, P.J.2    Yen, T.S.3
  • 139
    • 0026526978 scopus 로고
    • Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C
    • (1992) J Virol , vol.66 , Issue.2 , pp. 983-991
    • Lucito, R.1    Schneider, R.J.2
  • 140
  • 151
    • 0029895723 scopus 로고    scopus 로고
    • Hepatitis B virus HBx protein induces transcription factor AP-1 by activation of extracellular signal-regulated and c-jun N-terminal mitogen-activated protein kinases
    • (1996) J Virol , vol.70 , Issue.8 , pp. 4978-4985
    • Benn, J.1    Su, F.2    Doria, M.3    Schneider, R.J.4
  • 152
    • 0029982621 scopus 로고    scopus 로고
    • Hepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteins
    • (1996) J Virol , vol.70 , Issue.7 , pp. 4558-4566
    • Su, F.1    Schneider, R.J.2
  • 163
    • 0032566516 scopus 로고    scopus 로고
    • HBx protein of hepatitis B virus activates Jak1-STAT signaling
    • (1998) J Biol Chem , vol.273 , Issue.39 , pp. 25510-25515
    • Lee, Y.H.1    Yun, Y.2
  • 164
    • 0029776419 scopus 로고    scopus 로고
    • Increased expression of the insulin-like growth factor I (IGF-I) receptor gene in hepatocellular carcinoma cell lines: Implications of IGF-I receptor gene activation by hepatitis B virus X gene product
    • (1996) Cancer Res , vol.56 , Issue.16 , pp. 3831-3836
    • Kim, S.O.1    Park, J.G.2    Lee, Y.I.3
  • 169
    • 0029102383 scopus 로고
    • CrmA-inhibitable cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein during Fas- and tumor necrosis factor-induced apoptosis
    • (1995) J Biol Chem , vol.270 , Issue.32 , pp. 18738-18741
    • Tewari, M.1    Beidler, D.R.2    Dixit, V.M.3
  • 172
    • 0033634781 scopus 로고    scopus 로고
    • TNF-alpha signals apoptosis through a bid-dependent conformational change in Bax that is inhibited by E1B 19K
    • (2000) Mol Cell , vol.6 , Issue.1 , pp. 53-63
    • Perez, D.1    White, E.2
  • 186
    • 0342905085 scopus 로고    scopus 로고
    • Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential
    • (2000) J Virol , vol.74 , Issue.6 , pp. 2840-2846
    • Rahmani, Z.1    Huh, K.W.2    Lasher, R.3    Siddiqui, A.4


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