Historical perspective on airway smooth muscle: The saga of a frustrated cell

Journal of Applied Physiology

Volumn 91, Issue 2, 2001, Pages 938-952

  Seow, C Y ^a   Fredberg, J J ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Asthma; Bronchospasm; Hyperresponsiveness; Myosin; Obstruction; Plasticity

Indexed keywords

MYOSIN;

AIRWAY; AIRWAY OBSTRUCTION; ARTICLE; ASTHMA; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CYTOSKELETON; MUSCLE FORCE; PLASTICITY; PRIORITY JOURNAL; PROTEIN BINDING; SMOOTH MUSCLE; SMOOTH MUSCLE CONTRACTILITY; TIDAL VOLUME;

EID: 0034911891     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2001.91.2.938     Document Type: Article

References (169)

1. Airway stability and heterogeneity in the constricted lung
2. Mechanical alterations of airway smooth muscle in a canine asthmatic model
3. Neural mechanisms in asthma: New developments
4. Airway smooth muscle in asthma
5. What determines asthma phenotype? Is it the interaction between allergy and the smooth muscle?
6. Central airways behave more stiffly during forced expiration in patients with asthma
7. Individual airway constrictor response heterogeneity to histamine assessed by high resolution computed tomography
8. Delayed distension of contracted airways with lung inflation in vivo
9. The myth of maximal airway responsiveness in vivo
10. Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response
11. Control of cross-bridge cycling by myosin light chain phosphorylation in mammalian smooth muscle
12. Neuropeptides and asthma
13. Pulmonary conductance and elastic recoil relationships in asthma and emphysema
14. Effect of histamine, serotonin, and acetylcholine on the peripheral airways
15. Constriction of isolated living liquid-filled dog and cat lungs with histamine
16. Thick myofilaments in contracted and relaxed mammalian smooth muscle cells
17. Light chain phosphorylation controls the conformation of vertebrate non-muscle and smooth muscle molecules
18. Effect of bronchomotor tone on static mechanical properties of lung and ventilation distribution
19. Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma
20. Active site trapping of nucleotide by smooth and non-muscle myosins
21. Myosin phosphorylation and the crossbridge cycle in arterial smooth muscle
22. Effects of lung volume on maximal methacholine-induced bronchoconstriction in normal humans
23. Contributions to the physiology of the lungs. Part I. The bronchial muscles, their innervation, and the action of drugs upon them
24. Human lung parenchyma responds to contractile stimulation
25. The capacity of air passages under varying physiological conditions
26. Bronchial responsiveness among inbred mouse strains. Role of airway smooth-muscle shortening velocity
27. Ueber die wirkung der bronchialmuskeln, nach einer neuen methode untersucht, und ueber asthma nervosum
28. Airway responsiveness in two inbred strains of mouse disparate in IgE and IL-4 production
29. Preparation of individual smooth muscle cells from the stomach of Bufo Marinus
30. Regulation of bronchomotor tone by lung inflation in asthmatic and nonasthmatic subjects
31. Frozen objects: Small airways, big breaths, and asthma
32. Tissue resistance and the contractile state of lung parenchyma
33. Nonhomogeneity of lung response to inhaled histamine assessed with alveolar capsules
34. Airway smooth muscle, tidal stretches, and dynamically determined contractile states
35. Perturbed equilibrium of myosin binding in airway smooth muscle and its implications in bronchospasm
36. Friction in airway smooth muscle: Mechanism, latch and implications in asthma
37. The regular occurrence of thick filaments in stretch mammalian smooth muscle
38. The site and state of myosin in intestinal smooth muscle
39. Caldesmon and calponin phosphorylation in regulation of smooth muscle contraction
40. Density of myosin filaments in the rat anococcygeus muscle, at rest and in contraction
41. Analysis of the birefringence of the smooth muscle, anococcygeus of the rat, at rest and in contraction
42. Actin compliance: Are you pulling my chain?
43. The variation in isometric tension with sarcomere length in vertebrate muscle fibres
44. Relaxation of activated airway smooth muscle: Relative potency of isoproterenol versus tidal stretch
45. Applicability of the sliding filament/crossbridge paradigm to smooth muscle
46. Contractile force of airway smooth muscle during cyclic length changes
47. Effect of length history on contractile behavior of canine tracheal smooth muscle
48. Mechanisms for the mechanical placticity of tracheal smooth muscle
49. Mechanical modulation of pressure-volume characteristics of contracted canine airways in vitro
50. Parenchymal interdependence and airway response to methacholine in excised dog lobes
51. Plasticity of airway smooth muscle stiffness and extensibility: Role of length-adaptive mechanisms
52. Contraction history modulates isotonic shortening velocity in smooth muscle
53. A model for the coregulation of smooth muscle actomyosin by caldesmon, calponin, tropomyosin, and the myosin regulatory light chain
54. 2+, crossbridge, phosphorylation, and contraction
55. Cross-bridge phosphorylation and regulation of latch state in smooth muscle
56. Regulation of shortening velocity by cross-bridge phosphorylation in smooth muscle
57. 2+ activates cross-bridge phosphorylation and latch state in smooth muscle
58. Molecular mechanisms of phenotypic plasticity in smooth muscle cells
59. Length vs. active force relationship in single isolated smooth muscle cells
60. A role for p38(MAPK)/HSP27 pathway in smooth muscle cell migration
61. Phosphorylation of caldesmon by ERK MAP kinases in smooth muscle
62. p38 mitogen-activated protein kinase expression and activation in smooth muscle
63. The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthma
64. The genetic basis of atopic asthma
65. Mechanisms of smooth muscle contraction
66. Antibodies probe for folded monomeric myosin in relaxed and contracted smooth muscle
67. Nonuniform expansion of constricted dog lungs
68. Muscle structure and theories of contraction
69. X-ray diffraction measurements of the extensibility of actin and myosin filaments in contracting muscle
70. Remodelling of the contractile apparatus of striated muscle stimulated electronically in a shortened position
71. Investigation and assessment of airway and lung inflammation: We now have the tools, what are the questions?
72. Airway caliber in healthy and asthmatic subjects: Effects of bronchial challenge and deep inspirations
73. ATP hydrolysis during contraction of permeabilized airway smooth muscle
74. Potential usefulness of inhibiting neural mechanisms in asthma
75. Neural mechanisms in asthma
76. Axial distortion of airways in the lung
77. Potent bronchoprotective effect of deep inspiration and its absence in asthma
78. Localization of myosin filaments in smooth muscle
79. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
80. Time course of increased airway narrowing caused by inhibition of deep inspiration during methacholine challenge
81. The mechanics of exaggerated airway narrowing in asthma: The role of smooth muscle
82. Myosin thick filament lability induced by mechanical strain in airway smooth muscle
83. Elasticity analysis of lung deformation problems
84. Lung parenchymal shear modulus, airway wall remodeling, and bronchial hyperresponsiveness
85. Functional significance of increased airway smooth muscle in asthma and COPD
86. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
87. Effects of lung inflation on airway and tissue responses to aerosol histamine
88. Smooth-muscle myosin heavy-chain SM-B isoform expression in developing and adult rat lung
89. Regional variability in the collateral resistance response to histamine in the dog: Effects of cyclooxygenase inhibition
90. Partitioning of pulmonary resistance during constriction in the dog: Effects of volume history
91. Temporal and regional variability of the collateral resistance response to histamine in canine lungs
92. Differential responses of tissue viscance and collateral resistance to histamine and leukotriene C4
93. Relationship between heterogeneous changes in airway morphometry and lung resistance and elastance
94. Simple freezing apparatus for resolving rapid metabolic events associated with smooth muscle activation
95. Airway obstruction and collateral ventilation
96. Bronchial hyperresponsiveness
97. The clinical relevance of respiratory muscle research
98. A hypothesis linking bronchial hyperreactivity and airway inflammation: Implications for therapy
99. A theoretical analysis of the effect of airway smooth muscle load on airway narrowing
100. Importance of time interval between FEV 1 measurements in a methacholine provocation test
101. Videomicroscopy of methacholine-induced contraction of individual airways in precisioncut lung slices
102. The contribution of airway smooth muscle to airway narrowing and airway hyperresponsiveness in disease
103. Respiration: Pulmonary mechanics
104. Stress distribution in lungs: A model of pulmonary elasticity
105. Actin polymerization stimulated by contractile activation regulates force development in canine tracheal smooth muscle
106. 2+-insensitive contraction and paxillin tyrosine phosphorylation in smooth muscle
107. On the theory of muscle contraction: Filament extensibility and the development of isometric force and stiffness
108. Perturbed equilibria of myosin binding in airway smooth muscle: Bondlength distributions, mechanics, and ATP metabolism
109. Geometric hysteresis in pulmonary surface-to-volume ratio during tidal breathing
110. On the functional consequences of bronchial basement membrane thickening
111. Force-velocity relation and myosin light chain phosphorylation in bovine coronary arterial smooth muscle
112. Heterogeneity of responsiveness of individual airways in cultured lung explants
113. Relationship between myosin phosphorylation and contractile capability of canine airway smooth muscle
114. Assessment of airway tone in asthma
115. Effect of deep inspiration on methacholine dose-response curves in normal subjects
116. Mechanics of airway narrowing
117. Limitation of airway smooth muscle shortening by cartilage stiffness and lung elastic recoil in rabbits
118. Muscle cells of hollow organs
119. What is special about smooth muscle? The significance of covalent crossbridge regulation
120. Effect of maturational changes in myosin content and morphometry on airway smooth muscle contraction
121. 4
122. Proteins of the contractile mechanism of mammalian smooth muscle and their possible location in the cell
123. Lung contractility: Disposition, quantities and physiological effects of a-actin in rat and guinea pig lungs
124. Rigidity of tracheae and bronchi during muscular constriction
125. Adenosine triphosphate activity and "thick filament" formation of chicken gizzard myosin in low salt media
126. Electron microscopic studies of myosin molecules from chicken gizzard muscle II: The effect of thiophosphorylation of the 20 K-dalton light chain on the ATP-induced change in the conformation of myosin monomers
127. Electronmicroscope studies of myosin molecules from chicken gizzard muscle. I. The formation of the intramolecular loop in the myosin tail
128. A perspective of respiratory mechanics
129. Airway closure and reopening assessed by the alveolar capsule oscillation technique
130. The comparative mechanics and morphology of airways in asthma and in chronic obstructive pulmonary-disease
131. Historical perspectives: Plasticity of mammalian skeletal muscle
132. Plasticity in canine airway smooth muscle
133. The organization of contractile filaments in a mammalian smooth muscle
134. Inhibition of myosin light chain kinase by p21-activated kinase
135. Hysteresis of contracted airway smooth muscle
136. Spontaneous peristaltic airway contractions propel lung liquid through the bronchial tree of intact and fetal lung explants
137. Deep inspiration-induced bronchoprotection is stronger than bronchodilation
138. The lack of the bronchoprotective and not the bronchodilatory ability of deep inspiration is associated with airway hyperresponsiveness
139. Series-to-parallel transition in the filament lattice of airway smooth muscle
140. Effect of tidal volume and frequency on airway responsiveness in mechanically ventilated rabbits
141. Mechanisms for the mechanical response of airway smooth muscle to length oscillations
142. An electronmicroscope study of the influence of divalent ions on myosin filament formation in chicken gizzard extracts and homogenate
143. Airway hyperresponsiveness in asthma: A problem of limited smooth muscle relaxation with inspiration
144. ++-linked phosphorylation of a light chain of vertebrate smooth muscle myosin
145. Perhaps airway smooth muscle dysfunction does contribute to bronchial hyperresponsiveness after all
146. Filament organization in vertebrate smooth muscle
147. Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II
148. Contractility in bronchial airway smooth muscle cells obtained from asthmatic subjects by endobronchial biopsy is increased
149. Avalanches and power-law behaviour in lung inflation
150. Structure and function of chicken gizzard myosin
151. Maximal airway responses in mature and immature rabbits during tidal ventilation
152. Airway muscle stereology: Implications for increased shortening in asthma
153. A bent monomeric conformation myosin from smooth muscle
154. Isometric and isotonic length-tension relations and variation in cell length in longitudinal smooth muscle from rabbit urinary bladder
155. X-ray diffraction evidence for the extensibility of actin and myosin filaments during muscle contraction
156. In vitro bronchial responsiveness in two highly inbred rat strains
157. Effect of chronic passive length change on airway smooth muscle length-tension relationship
158. Effect of length oscillation on the subsequent force development in swine tracheal smooth muscle
159. Rho A regulates sustained smooth muscle contraction through cytoskeletal reorganization of HSP27
160. Limitation of maximal bronchoconstriction in living dogs
161. X-ray diffraction study on mammalian visceral smooth muscle in resting and activated states
162. 2+-independent phosphorylation of myosin in rat caudal artery and chicken gizzard myofilaments
163. Regulation of tracheobronchial smooth muscle
164. A model of airway narrowing in asthma and in chronic obstructive pulmonary disease
165. The shape of the dose-response curve to histamine in asthmatic and normal subjects
166. Epidemiology of bronchial hyperresponsiveness
167. Polymerization of myosin on activation of rat anococcygeus smooth muscle
168. Evidence for modulation of smooth muscle force by the p38 MAP kinase/HSP27 pathway